ATE307588T1 - Pharmazeutische formulierung enhaltend midazolam zur buccalen verabreichung - Google Patents
Pharmazeutische formulierung enhaltend midazolam zur buccalen verabreichungInfo
- Publication number
- ATE307588T1 ATE307588T1 AT02258924T AT02258924T ATE307588T1 AT E307588 T1 ATE307588 T1 AT E307588T1 AT 02258924 T AT02258924 T AT 02258924T AT 02258924 T AT02258924 T AT 02258924T AT E307588 T1 ATE307588 T1 AT E307588T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical formulation
- formulation containing
- midazolam
- buccal administration
- containing midazolam
- Prior art date
Links
- 229960003793 midazolam Drugs 0.000 title abstract 2
- DDLIGBOFAVUZHB-UHFFFAOYSA-N midazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NC=C2CN=C1C1=CC=CC=C1F DDLIGBOFAVUZHB-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- XYGVIBXOJOOCFR-BTJKTKAUSA-N (z)-but-2-enedioic acid;8-chloro-6-(2-fluorophenyl)-1-methyl-4h-imidazo[1,5-a][1,4]benzodiazepine Chemical compound OC(=O)\C=C/C(O)=O.C12=CC(Cl)=CC=C2N2C(C)=NC=C2CN=C1C1=CC=CC=C1F XYGVIBXOJOOCFR-BTJKTKAUSA-N 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 230000001037 epileptic effect Effects 0.000 abstract 1
- 229960004653 midazolam maleate Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0130964.0A GB0130964D0 (en) | 2001-12-24 | 2001-12-24 | Pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE307588T1 true ATE307588T1 (de) | 2005-11-15 |
Family
ID=9928404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02258924T ATE307588T1 (de) | 2001-12-24 | 2002-12-20 | Pharmazeutische formulierung enhaltend midazolam zur buccalen verabreichung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6936605B2 (de) |
| EP (1) | EP1323422B8 (de) |
| AT (1) | ATE307588T1 (de) |
| DE (1) | DE60206871T2 (de) |
| ES (1) | ES2250594T3 (de) |
| GB (1) | GB0130964D0 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0400804D0 (en) | 2004-01-14 | 2004-02-18 | Innoscience Technology Bv | Pharmaceutical compositions |
| KR100755872B1 (ko) | 2006-10-02 | 2007-09-05 | 충남대학교산학협력단 | 미다졸람을 함유하는 염증 예방 및 치료용 약제학적 조성물 |
| US20080138383A1 (en) * | 2006-12-07 | 2008-06-12 | Jonathan David Bortz | Compositions and methods for treating seizures |
| US20080275030A1 (en) | 2007-01-19 | 2008-11-06 | Sveinbjorn Gizurarson | Methods and Compositions for the Delivery of a Therapeutic Agent |
| WO2010025316A1 (en) * | 2008-08-29 | 2010-03-04 | Jeffrey Comanor | Composition and methods for relief of neuropathological pain |
| US8932645B2 (en) | 2008-08-29 | 2015-01-13 | Coastal Biologic Solutions | Composition and methods for relief of chemical sensitivity |
| GB2481407B (en) | 2010-06-22 | 2012-05-23 | Special Products Ltd | A rapid onset liquid midazolam composition for buccal administration |
| WO2019186515A1 (en) * | 2018-03-30 | 2019-10-03 | Ftf Pharma Private Limited | Liquid pharmaceutical compositions of antiepileptic drugs |
| EP3886856A4 (de) * | 2018-11-29 | 2022-01-19 | Zucco Sassi Yonezawa Siviglia, Debora | Verfahren zur behandlung oder vorbeugung von anfällen in zusammenhang mit einer epileptischen erkrankung |
| US11446262B2 (en) | 2018-11-29 | 2022-09-20 | Debora Zucco Sassi Yonezawa Siviglia | Neuroquiescence—a treatment for neurodevelopmental and neurodegenerative bioelectrical dysregulation and demyelination |
| EP3982970A1 (de) | 2019-06-12 | 2022-04-20 | F. Hoffmann-La Roche AG | Neue behandlung von sma |
| CN113209013B (zh) * | 2021-06-24 | 2023-04-07 | 新疆特丰药业股份有限公司 | 一种咪达唑仑液体制剂及其制备方法和用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6049080A (ja) * | 1983-08-27 | 1985-03-18 | Hayashibara Biochem Lab Inc | 摺動部シ−ル剤 |
| GB9717770D0 (en) | 1997-08-21 | 1997-10-29 | Scherer Ltd R P | Pharmaceutical composition |
| US6319510B1 (en) | 1999-04-20 | 2001-11-20 | Alayne Yates | Gum pad for delivery of medication to mucosal tissues |
| WO2001030391A2 (en) | 1999-10-27 | 2001-05-03 | Farmarc Nederland Bv | Pharmaceutical composition containing midazolam |
-
2001
- 2001-12-24 GB GBGB0130964.0A patent/GB0130964D0/en not_active Ceased
-
2002
- 2002-12-12 US US10/317,518 patent/US6936605B2/en not_active Expired - Lifetime
- 2002-12-20 EP EP02258924A patent/EP1323422B8/de not_active Expired - Lifetime
- 2002-12-20 AT AT02258924T patent/ATE307588T1/de not_active IP Right Cessation
- 2002-12-20 ES ES02258924T patent/ES2250594T3/es not_active Expired - Lifetime
- 2002-12-20 DE DE60206871T patent/DE60206871T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20030130267A1 (en) | 2003-07-10 |
| DE60206871T2 (de) | 2006-06-08 |
| EP1323422B8 (de) | 2006-03-08 |
| HK1057699A1 (en) | 2004-04-16 |
| EP1323422A1 (de) | 2003-07-02 |
| DE60206871D1 (de) | 2005-12-01 |
| EP1323422B1 (de) | 2005-10-26 |
| GB0130964D0 (en) | 2002-02-13 |
| ES2250594T3 (es) | 2006-04-16 |
| US6936605B2 (en) | 2005-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |