ATE307809T1 - Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung - Google Patents

Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung

Info

Publication number
ATE307809T1
ATE307809T1 AT99954472T AT99954472T ATE307809T1 AT E307809 T1 ATE307809 T1 AT E307809T1 AT 99954472 T AT99954472 T AT 99954472T AT 99954472 T AT99954472 T AT 99954472T AT E307809 T1 ATE307809 T1 AT E307809T1
Authority
AT
Austria
Prior art keywords
pyrimidine derivatives
production
novel pyrimidine
novel
possess
Prior art date
Application number
AT99954472T
Other languages
English (en)
Inventor
Jong Wook Lee
Bong Yong Lee
Chang Seop Kim
Seung Kyu Lee
Song Jin Lee
Original Assignee
Yuhan Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp Ltd filed Critical Yuhan Corp Ltd
Application granted granted Critical
Publication of ATE307809T1 publication Critical patent/ATE307809T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99954472T 1998-11-17 1999-11-09 Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung ATE307809T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980049164A KR100272471B1 (ko) 1998-11-17 1998-11-17 신규의 피리미딘 유도체 및 그의 제조방법
PCT/KR1999/000669 WO2000029403A1 (en) 1998-11-17 1999-11-09 Novel pyrimidine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
ATE307809T1 true ATE307809T1 (de) 2005-11-15

Family

ID=36201265

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99954472T ATE307809T1 (de) 1998-11-17 1999-11-09 Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung

Country Status (17)

Country Link
US (1) US6545008B1 (de)
EP (1) EP1131312B1 (de)
JP (1) JP2002530280A (de)
KR (1) KR100272471B1 (de)
CN (1) CN1159312C (de)
AT (1) ATE307809T1 (de)
AU (1) AU762098B2 (de)
BR (1) BR9915323A (de)
CA (1) CA2351644A1 (de)
DE (1) DE69927997T2 (de)
ES (1) ES2251234T3 (de)
HK (1) HK1041000B (de)
HU (1) HUP0104533A3 (de)
MX (1) MXPA01004457A (de)
RU (1) RU2236407C2 (de)
TR (1) TR200101388T2 (de)
WO (1) WO2000029403A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0110338D0 (en) * 2001-04-27 2001-06-20 Sb Pharmco Inc Novel processes
WO2005009980A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
EP1974730A1 (de) 2003-11-03 2008-10-01 AstraZeneca AB Imidazo[1,2-a]pyridin-Derivate zur Behandlung von Schlafstörungen durch stummen gastroösophagealen Reflux
BRPI0616575A2 (pt) * 2005-09-27 2011-06-21 Irm Llc compostos e composições contendo diarilamina, seu uso como moduladores de receptores de c-kit bem como método para sua produção
MX2012000275A (es) 2009-07-09 2012-02-08 Raqualia Pharma Inc Antagonista de bomba de acido para el tratamiento de enfermedades involucradas en la motilidad gastrointestinal anormal.
EA035349B1 (ru) 2012-11-21 2020-05-29 ПиТиСи ТЕРАПЬЮТИКС, ИНК. ЗАМЕЩЕННЫЕ ПИРИМИДИНОВЫЕ ОБРАТНЫЕ ИНГИБИТОРЫ Bmi-1
WO2015030847A1 (en) 2013-08-30 2015-03-05 Ptc Therapeutics, Inc. Substituted pyrimidine bmi-1 inhibitors
WO2015076800A1 (en) 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors
AU2019340402B2 (en) 2018-08-17 2025-04-03 Ptc Therapeutics, Inc. Method for treating pancreatic cancer

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
FR2640582B1 (fr) 1988-12-21 1991-08-16 Gerard Megret Procede d'habillage d'elements de boites montees et installation pour la mise en oeuvre de ce procede
EP0388838B1 (de) 1989-03-22 1996-01-10 Ciba-Geigy Ag Schädlingsbekämpfungsmittel
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
EP0556310B1 (de) 1990-11-06 1995-07-05 Pfizer Inc. Chinazolinderivate um die antitumorwirkung zu verbessern
ES2068714T3 (es) 1991-04-17 1995-04-16 Pfizer Derivados de pirimidina para aumentar la actividad antitumoral.
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
DK0640599T3 (da) 1993-08-26 1998-09-28 Ono Pharmaceutical Co 4-Aminopyrimidin-derivater
WO1995010506A1 (en) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyl-n-arylpyrimidinamines and derivatives thereof
CN1102144C (zh) * 1994-08-13 2003-02-26 株式会社柳韩洋行 新的嘧啶衍生物及其制备方法
WO1997042186A1 (en) * 1996-05-04 1997-11-13 Yuhan Corporation Process for preparation of pyrimidine derivatives
BR9712392A (pt) * 1996-10-29 2000-01-25 Yuhan Corp Processos para preparar 5,6-dimetil-2-(4-fluorofenil-amino) -4- (1-metil-1,2,3,4 - tetraidroisoquinolin - 2 -il) pirimidina, 4 - halogeno - 2 - (4 - fluorofenilamino) -5,6 -dimetil-pirimidina e 1-metil-1,2,3,4-tetraidroisoquinolina, e, derivado de pirimidina
IN188411B (de) 1997-03-27 2002-09-21 Yuhan Corp

Also Published As

Publication number Publication date
ES2251234T3 (es) 2006-04-16
HUP0104533A3 (en) 2003-01-28
AU1081200A (en) 2000-06-05
US6545008B1 (en) 2003-04-08
MXPA01004457A (es) 2004-04-05
DE69927997T2 (de) 2006-07-27
JP2002530280A (ja) 2002-09-17
CN1326453A (zh) 2001-12-12
EP1131312A1 (de) 2001-09-12
HK1041000A1 (en) 2002-06-28
HK1041000B (zh) 2004-12-31
WO2000029403A1 (en) 2000-05-25
AU762098B2 (en) 2003-06-19
KR100272471B1 (ko) 2000-11-15
EP1131312B1 (de) 2005-10-26
KR20000032633A (ko) 2000-06-15
DE69927997D1 (de) 2005-12-01
RU2236407C2 (ru) 2004-09-20
HUP0104533A2 (hu) 2002-04-29
BR9915323A (pt) 2001-08-07
CA2351644A1 (en) 2000-05-25
TR200101388T2 (tr) 2001-10-22
CN1159312C (zh) 2004-07-28

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