ATE307809T1 - Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung - Google Patents

Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung

Info

Publication number
ATE307809T1
ATE307809T1 AT99954472T AT99954472T ATE307809T1 AT E307809 T1 ATE307809 T1 AT E307809T1 AT 99954472 T AT99954472 T AT 99954472T AT 99954472 T AT99954472 T AT 99954472T AT E307809 T1 ATE307809 T1 AT E307809T1
Authority
AT
Austria
Prior art keywords
pyrimidine derivatives
production
novel pyrimidine
novel
possess
Prior art date
Application number
AT99954472T
Other languages
English (en)
Inventor
Jong Wook Lee
Bong Yong Lee
Chang Seop Kim
Seung Kyu Lee
Song Jin Lee
Original Assignee
Yuhan Corp Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp Ltd filed Critical Yuhan Corp Ltd
Application granted granted Critical
Publication of ATE307809T1 publication Critical patent/ATE307809T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT99954472T 1998-11-17 1999-11-09 Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung ATE307809T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980049164A KR100272471B1 (ko) 1998-11-17 1998-11-17 신규의 피리미딘 유도체 및 그의 제조방법
PCT/KR1999/000669 WO2000029403A1 (en) 1998-11-17 1999-11-09 Novel pyrimidine derivatives and processes for the preparation thereof

Publications (1)

Publication Number Publication Date
ATE307809T1 true ATE307809T1 (de) 2005-11-15

Family

ID=36201265

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99954472T ATE307809T1 (de) 1998-11-17 1999-11-09 Neuartige pyrimidin-derivate und verfahren zu ihrer herstellung

Country Status (17)

Country Link
US (1) US6545008B1 (de)
EP (1) EP1131312B1 (de)
JP (1) JP2002530280A (de)
KR (1) KR100272471B1 (de)
CN (1) CN1159312C (de)
AT (1) ATE307809T1 (de)
AU (1) AU762098B2 (de)
BR (1) BR9915323A (de)
CA (1) CA2351644A1 (de)
DE (1) DE69927997T2 (de)
ES (1) ES2251234T3 (de)
HK (1) HK1041000B (de)
HU (1) HUP0104533A3 (de)
MX (1) MXPA01004457A (de)
RU (1) RU2236407C2 (de)
TR (1) TR200101388T2 (de)
WO (1) WO2000029403A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0110338D0 (en) * 2001-04-27 2001-06-20 Sb Pharmco Inc Novel processes
WO2005009980A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
KR20060099524A (ko) 2003-11-03 2006-09-19 아스트라제네카 아베 무증상 위식도 역류의 치료를 위한 이미다조[1,2-ａ]피리딘유도체
KR101415426B1 (ko) * 2005-09-27 2014-07-04 아이알엠 엘엘씨 디아릴아민-함유 화합물 및 조성물, 및 ｃ-ｋｉｔ 수용체의조절제로서의 그의 용도
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
NZ746607A (en) 2012-11-21 2019-11-29 Ptc Therapeutics Inc Substituted reverse pyrimidine bmi-1 inhibitors
EA034866B1 (ru) 2013-08-30 2020-03-31 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Замещенные пиримидиновые ингибиторы bmi-1
WO2015076800A1 (en) 2013-11-21 2015-05-28 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine bmi-1 inhibitors
EP3836932A2 (de) 2018-08-17 2021-06-23 PTC Therapeutics, Inc. Verfahren zur behandlung von bauchspeicheldrüsenkrebs

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
FR2640582B1 (fr) 1988-12-21 1991-08-16 Gerard Megret Procede d'habillage d'elements de boites montees et installation pour la mise en oeuvre de ce procede
DE59010042D1 (de) 1989-03-22 1996-02-22 Ciba Geigy Ag Schädlingsbekämpfungsmittel
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
DK0556310T3 (da) 1990-11-06 1995-08-21 Pfizer Quinazolinderivater til forhøjelse af antitumoraktivitet
CZ390992A3 (en) 1991-04-17 1994-03-16 Pfizer Pyrimidine derivatives, process of their preparation and use as substances for increase of anti-tumor activity
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
DK0640599T3 (da) 1993-08-26 1998-09-28 Ono Pharmaceutical Co 4-Aminopyrimidin-derivater
WO1995010506A1 (en) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyl-n-arylpyrimidinamines and derivatives thereof
JP2896532B2 (ja) * 1994-08-13 1999-05-31 ユーハン コーポレーション 新規なピリミジン誘導体およびその製造方法
CN1190427C (zh) * 1996-05-04 2005-02-23 株式会社柳韩洋行 制备嘧啶衍生物的方法
WO1998018784A1 (en) * 1996-10-29 1998-05-07 Yuhan Corporation Process for preparation of pyrimidine derivatives
IN188411B (de) 1997-03-27 2002-09-21 Yuhan Corp

Also Published As

Publication number Publication date
AU1081200A (en) 2000-06-05
KR100272471B1 (ko) 2000-11-15
MXPA01004457A (es) 2004-04-05
EP1131312B1 (de) 2005-10-26
HUP0104533A2 (hu) 2002-04-29
HK1041000B (zh) 2004-12-31
CN1159312C (zh) 2004-07-28
KR20000032633A (ko) 2000-06-15
DE69927997D1 (de) 2005-12-01
US6545008B1 (en) 2003-04-08
JP2002530280A (ja) 2002-09-17
HUP0104533A3 (en) 2003-01-28
DE69927997T2 (de) 2006-07-27
BR9915323A (pt) 2001-08-07
ES2251234T3 (es) 2006-04-16
HK1041000A1 (en) 2002-06-28
RU2236407C2 (ru) 2004-09-20
CA2351644A1 (en) 2000-05-25
TR200101388T2 (tr) 2001-10-22
EP1131312A1 (de) 2001-09-12
CN1326453A (zh) 2001-12-12
WO2000029403A1 (en) 2000-05-25
AU762098B2 (en) 2003-06-19

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