ATE308049T1 - Verfahren zur identifizierung von verbindungen die das mehrschichtige squamosus epithelium gegen schädliche substanzen schützen - Google Patents

Verfahren zur identifizierung von verbindungen die das mehrschichtige squamosus epithelium gegen schädliche substanzen schützen

Info

Publication number
ATE308049T1
ATE308049T1 AT01959274T AT01959274T ATE308049T1 AT E308049 T1 ATE308049 T1 AT E308049T1 AT 01959274 T AT01959274 T AT 01959274T AT 01959274 T AT01959274 T AT 01959274T AT E308049 T1 ATE308049 T1 AT E308049T1
Authority
AT
Austria
Prior art keywords
squamosus
protect
layer
harmful substances
identifying compounds
Prior art date
Application number
AT01959274T
Other languages
English (en)
Inventor
Nelia A Tobey
Roy C Orlando
Original Assignee
Univ Tulane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tulane filed Critical Univ Tulane
Application granted granted Critical
Publication of ATE308049T1 publication Critical patent/ATE308049T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01959274T 2000-07-28 2001-07-26 Verfahren zur identifizierung von verbindungen die das mehrschichtige squamosus epithelium gegen schädliche substanzen schützen ATE308049T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62619600A 2000-07-28 2000-07-28
PCT/US2001/023717 WO2002010767A2 (en) 2000-07-28 2001-07-26 Assay methods for identifying compounds which may protect stratified squamous epithelium against damage by noxious substances

Publications (1)

Publication Number Publication Date
ATE308049T1 true ATE308049T1 (de) 2005-11-15

Family

ID=24509364

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01959274T ATE308049T1 (de) 2000-07-28 2001-07-26 Verfahren zur identifizierung von verbindungen die das mehrschichtige squamosus epithelium gegen schädliche substanzen schützen

Country Status (8)

Country Link
EP (1) EP1352247B1 (de)
AR (1) AR030000A1 (de)
AT (1) ATE308049T1 (de)
AU (1) AU2001280847A1 (de)
CA (1) CA2418377A1 (de)
DE (1) DE60114460T2 (de)
PE (1) PE20020227A1 (de)
WO (1) WO2002010767A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402660B2 (en) 2000-08-02 2008-07-22 The Johns Hopkins University Endothelial cell expression patterns
WO2007045247A2 (en) * 2005-10-19 2007-04-26 Enkam Pharmaceuticals A/S Fibroblast growth factor receptor-derived peptides
WO2010138851A2 (en) 2009-05-29 2010-12-02 The University Of North Carolina At Chapel Hill E-cadherin as a biomarker of gastroesophageal reflux disease
CN106471130A (zh) * 2014-05-09 2017-03-01 杰克逊实验室 鉴定改变iRhom多肽活性的化合物的方法及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189056A (en) * 1989-12-19 1993-02-23 University Of North Carolina At Chapel Hill Protection of moist stratified squamous epithelia against damage from noxious luminal agents

Also Published As

Publication number Publication date
WO2002010767A3 (en) 2003-07-17
CA2418377A1 (en) 2002-02-07
AR030000A1 (es) 2003-07-23
EP1352247B1 (de) 2005-10-26
DE60114460T2 (de) 2006-07-13
WO2002010767A2 (en) 2002-02-07
DE60114460D1 (de) 2005-12-01
PE20020227A1 (es) 2002-04-02
EP1352247A2 (de) 2003-10-15
AU2001280847A1 (en) 2002-02-13

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