ATE308114T1 - Verfahren und vorrichtung zur clusterfragmentation - Google Patents
Verfahren und vorrichtung zur clusterfragmentationInfo
- Publication number
- ATE308114T1 ATE308114T1 AT00956226T AT00956226T ATE308114T1 AT E308114 T1 ATE308114 T1 AT E308114T1 AT 00956226 T AT00956226 T AT 00956226T AT 00956226 T AT00956226 T AT 00956226T AT E308114 T1 ATE308114 T1 AT E308114T1
- Authority
- AT
- Austria
- Prior art keywords
- cluster
- fragmentation
- analysis
- reaction partner
- cluster fragmentation
- Prior art date
Links
- 238000013467 fragmentation Methods 0.000 title abstract 6
- 238000006062 fragmentation reaction Methods 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F03—MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
- F03H—PRODUCING A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
- F03H1/00—Using plasma to produce a reactive propulsive thrust
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J27/00—Ion beam tubes
- H01J27/02—Ion sources; Ion guns
- H01J27/026—Cluster ion sources
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/02—Details
- H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
- H01J49/0459—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
- H01J49/0463—Desorption by laser or particle beam, followed by ionisation as a separate step
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H3/00—Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
- H05H3/02—Molecular or atomic-beam generation, e.g. resonant beam generation
Landscapes
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Plasma & Fusion (AREA)
- Analytical Chemistry (AREA)
- Optics & Photonics (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Electron Tubes For Measurement (AREA)
- Treating Waste Gases (AREA)
- Electrotherapy Devices (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19934173A DE19934173A1 (de) | 1999-07-21 | 1999-07-21 | Verfahren und Vorrichtung zur Clusterfragmentation |
| PCT/EP2000/006956 WO2001008196A2 (de) | 1999-07-21 | 2000-07-20 | Verfahren und vorrichtung zur clusterfragmentation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE308114T1 true ATE308114T1 (de) | 2005-11-15 |
Family
ID=7915529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00956226T ATE308114T1 (de) | 1999-07-21 | 2000-07-20 | Verfahren und vorrichtung zur clusterfragmentation |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7247845B1 (de) |
| EP (1) | EP1200984B1 (de) |
| JP (1) | JP2003505704A (de) |
| AT (1) | ATE308114T1 (de) |
| DE (2) | DE19934173A1 (de) |
| WO (1) | WO2001008196A2 (de) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6989528B2 (en) * | 2003-06-06 | 2006-01-24 | Ionwerks, Inc. | Gold implantation/deposition of biological samples for laser desorption three dimensional depth profiling of tissues |
| DE102004051785B4 (de) | 2004-10-25 | 2008-04-24 | Bruker Daltonik Gmbh | Proteinprofile mit Luft-MALDI |
| US7723678B2 (en) * | 2006-04-04 | 2010-05-25 | Agilent Technologies, Inc. | Method and apparatus for surface desorption ionization by charged particles |
| US8835880B2 (en) * | 2006-10-31 | 2014-09-16 | Fei Company | Charged particle-beam processing using a cluster source |
| JP5023886B2 (ja) * | 2007-08-28 | 2012-09-12 | 株式会社島津製作所 | 大気圧maldi質量分析装置 |
| US9144627B2 (en) | 2007-09-14 | 2015-09-29 | Exogenesis Corporation | Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby |
| US11199769B2 (en) | 2010-08-23 | 2021-12-14 | Exogenesis Corporation | Method and apparatus for neutral beam processing based on gas cluster ion beam technology |
| US10181402B2 (en) | 2010-08-23 | 2019-01-15 | Exogenesis Corporation | Method and apparatus for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
| US10202684B2 (en) | 2010-08-23 | 2019-02-12 | Exogenesis Corporation | Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
| US20170303383A1 (en) * | 2010-08-23 | 2017-10-19 | Exogenesis Corporation | Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
| US10825685B2 (en) | 2010-08-23 | 2020-11-03 | Exogenesis Corporation | Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby |
| US9799488B2 (en) * | 2010-08-23 | 2017-10-24 | Exogenesis Corporation | Method and apparatus for neutral beam processing based on gas cluster ion beam technology |
| CN103180030B (zh) * | 2010-08-23 | 2017-04-12 | 艾克索乔纳斯公司 | 基于气体团簇离子束技术的中性射束处理方法和设备 |
| US10670960B2 (en) | 2010-08-23 | 2020-06-02 | Exogenesis Corporation | Enhanced high aspect ratio etch performance using accelerated neutral beams derived from gas-cluster ion beams |
| US10556042B2 (en) | 2011-08-19 | 2020-02-11 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
| CA2845762C (en) | 2011-08-22 | 2019-01-08 | Exogenesis Corporation | Drug delivery system and method of manufacturing thereof |
| US9315798B2 (en) | 2011-08-22 | 2016-04-19 | Exogenesis Corporation | Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby |
| EP3699950B1 (de) | 2011-12-28 | 2026-01-28 | Micromass UK Limited | Kollisionsionengenerator und separator |
| JP5984424B2 (ja) * | 2012-02-27 | 2016-09-06 | 国立大学法人京都大学 | 基板洗浄方法、基板洗浄装置及び真空処理装置 |
| DE102012008259B4 (de) * | 2012-04-25 | 2014-06-26 | Bruker Daltonik Gmbh | Ionenerzeugung in Massenspektrometern durch Clusterbeschuss |
| DE102012011648B4 (de) | 2012-06-08 | 2018-06-14 | Bruker Daltonik Gmbh | Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie |
| DE102012011647B4 (de) | 2012-06-08 | 2020-07-02 | Bruker Daltonik Gmbh | Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie |
| GB201307792D0 (en) * | 2013-04-30 | 2013-06-12 | Ionoptika Ltd | Use of a water cluster ion beam for sample analysis |
| CA2977900A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Collision surface for improved ionisation |
| CA2978165A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Improved ionisation of gaseous samples |
| EP3264989B1 (de) | 2015-03-06 | 2023-12-20 | Micromass UK Limited | Spektrometrische analyse |
| JP6800875B2 (ja) | 2015-03-06 | 2020-12-16 | マイクロマス ユーケー リミテッド | 急速蒸発イオン化質量分析(「reims」)装置に連結されたイオンアナライザのための流入器具 |
| US11037774B2 (en) | 2015-03-06 | 2021-06-15 | Micromass Uk Limited | Physically guided rapid evaporative ionisation mass spectrometry (“REIMS”) |
| GB2551294B (en) | 2015-03-06 | 2021-03-17 | Micromass Ltd | Liquid trap or separator for electrosurgical applications |
| US11031222B2 (en) | 2015-03-06 | 2021-06-08 | Micromass Uk Limited | Chemically guided ambient ionisation mass spectrometry |
| US11139156B2 (en) * | 2015-03-06 | 2021-10-05 | Micromass Uk Limited | In vivo endoscopic tissue identification tool |
| WO2016142691A1 (en) | 2015-03-06 | 2016-09-15 | Micromass Uk Limited | Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of swabs and biopsy samples |
| US10978284B2 (en) | 2015-03-06 | 2021-04-13 | Micromass Uk Limited | Imaging guided ambient ionisation mass spectrometry |
| GB2556436B (en) | 2015-03-06 | 2022-01-26 | Micromass Ltd | Cell population analysis |
| GB2554206B (en) | 2015-03-06 | 2021-03-24 | Micromass Ltd | Spectrometric analysis of microbes |
| CN107533032A (zh) | 2015-03-06 | 2018-01-02 | 英国质谱公司 | 用于从块状组织直接映射的原位电离质谱测定成像平台 |
| EP3265822B1 (de) | 2015-03-06 | 2021-04-28 | Micromass UK Limited | Gewebeanalyse mittels massenspektrometrie oder ionenmobilitätsspektrometrie |
| GB201517195D0 (en) | 2015-09-29 | 2015-11-11 | Micromass Ltd | Capacitively coupled reims technique and optically transparent counter electrode |
| WO2017178833A1 (en) | 2016-04-14 | 2017-10-19 | Micromass Uk Limited | Spectrometric analysis of plants |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755344A (en) * | 1980-04-11 | 1988-07-05 | The United States Of America As Represented By The United States Department Of Energy | Method and apparatus for the production of cluster ions |
| US4378499A (en) * | 1981-03-31 | 1983-03-29 | The Bendix Corporation | Chemical conversion for ion mobility detectors using surface interactions |
| US5053343A (en) * | 1985-02-15 | 1991-10-01 | Environmental Technologies Group, Inc. | Selective ionization of gas constituents using electrolytic reactions |
| IL81375A (en) * | 1987-01-23 | 1990-11-05 | Univ Ramot | Method and apparatus for producing ions by surface ionization of energy-rich molecules and atoms |
| US4851669A (en) * | 1988-06-02 | 1989-07-25 | The Regents Of The University Of California | Surface-induced dissociation for mass spectrometry |
| US4935623A (en) * | 1989-06-08 | 1990-06-19 | Hughes Aircraft Company | Production of energetic atom beams |
| US5051582A (en) | 1989-09-06 | 1991-09-24 | The United States Of America As Represented By The Secretary Of The Air Force | Method for the production of size, structure and composition of specific-cluster ions |
| US5239820A (en) | 1991-11-18 | 1993-08-31 | California Institute Of Technology | Electric propulsion using C60 molecules |
| US5338931A (en) * | 1992-04-23 | 1994-08-16 | Environmental Technologies Group, Inc. | Photoionization ion mobility spectrometer |
| US5780862A (en) * | 1994-01-11 | 1998-07-14 | Siess; Harold E. | Method and apparatus for generating ions |
| US5577092A (en) * | 1995-01-25 | 1996-11-19 | Kublak; Glenn D. | Cluster beam targets for laser plasma extreme ultraviolet and soft x-ray sources |
| DE19617011C2 (de) * | 1996-04-27 | 2000-11-02 | Bruker Daltonik Gmbh | Matrixkomponentengemisch für die matrixunterstützte Laserdesorption und Ionisierung sowie Verfahren zur Zubereitung eines Matrixkomponentengemisches |
| US5767511A (en) * | 1996-07-25 | 1998-06-16 | Raytheon Company | Mean cluster size determination using water capture |
-
1999
- 1999-07-21 DE DE19934173A patent/DE19934173A1/de not_active Ceased
-
2000
- 2000-07-20 EP EP00956226A patent/EP1200984B1/de not_active Expired - Lifetime
- 2000-07-20 JP JP2001512616A patent/JP2003505704A/ja active Pending
- 2000-07-20 AT AT00956226T patent/ATE308114T1/de not_active IP Right Cessation
- 2000-07-20 DE DE50011459T patent/DE50011459D1/de not_active Expired - Lifetime
- 2000-07-20 WO PCT/EP2000/006956 patent/WO2001008196A2/de not_active Ceased
- 2000-07-20 US US10/031,542 patent/US7247845B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1200984A2 (de) | 2002-05-02 |
| WO2001008196A3 (de) | 2001-12-06 |
| DE50011459D1 (de) | 2005-12-01 |
| WO2001008196A2 (de) | 2001-02-01 |
| JP2003505704A (ja) | 2003-02-12 |
| DE19934173A1 (de) | 2001-01-25 |
| EP1200984B1 (de) | 2005-10-26 |
| US7247845B1 (en) | 2007-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |