ATE308114T1 - Verfahren und vorrichtung zur clusterfragmentation - Google Patents

Verfahren und vorrichtung zur clusterfragmentation

Info

Publication number
ATE308114T1
ATE308114T1 AT00956226T AT00956226T ATE308114T1 AT E308114 T1 ATE308114 T1 AT E308114T1 AT 00956226 T AT00956226 T AT 00956226T AT 00956226 T AT00956226 T AT 00956226T AT E308114 T1 ATE308114 T1 AT E308114T1
Authority
AT
Austria
Prior art keywords
cluster
fragmentation
analysis
reaction partner
cluster fragmentation
Prior art date
Application number
AT00956226T
Other languages
English (en)
Inventor
Christoph Gebhardt
Hartmut Schroeder
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of ATE308114T1 publication Critical patent/ATE308114T1/de

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F03MACHINES OR ENGINES FOR LIQUIDS; WIND, SPRING, OR WEIGHT MOTORS; PRODUCING MECHANICAL POWER OR A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03HPRODUCING A REACTIVE PROPULSIVE THRUST, NOT OTHERWISE PROVIDED FOR
    • F03H1/00Using plasma to produce a reactive propulsive thrust
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J27/00Ion beam tubes
    • H01J27/02Ion sources; Ion guns
    • H01J27/026Cluster ion sources
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0459Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for solid samples
    • H01J49/0463Desorption by laser or particle beam, followed by ionisation as a separate step
    • HELECTRICITY
    • H05ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05HPLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H3/00Production or acceleration of neutral particle beams, e.g. molecular or atomic beams
    • H05H3/02Molecular or atomic-beam generation, e.g. resonant beam generation

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Plasma & Fusion (AREA)
  • Analytical Chemistry (AREA)
  • Optics & Photonics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Electron Tubes For Measurement (AREA)
  • Treating Waste Gases (AREA)
  • Electrotherapy Devices (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
AT00956226T 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation ATE308114T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19934173A DE19934173A1 (de) 1999-07-21 1999-07-21 Verfahren und Vorrichtung zur Clusterfragmentation
PCT/EP2000/006956 WO2001008196A2 (de) 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation

Publications (1)

Publication Number Publication Date
ATE308114T1 true ATE308114T1 (de) 2005-11-15

Family

ID=7915529

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00956226T ATE308114T1 (de) 1999-07-21 2000-07-20 Verfahren und vorrichtung zur clusterfragmentation

Country Status (6)

Country Link
US (1) US7247845B1 (de)
EP (1) EP1200984B1 (de)
JP (1) JP2003505704A (de)
AT (1) ATE308114T1 (de)
DE (2) DE19934173A1 (de)
WO (1) WO2001008196A2 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989528B2 (en) * 2003-06-06 2006-01-24 Ionwerks, Inc. Gold implantation/deposition of biological samples for laser desorption three dimensional depth profiling of tissues
DE102004051785B4 (de) 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
US7723678B2 (en) * 2006-04-04 2010-05-25 Agilent Technologies, Inc. Method and apparatus for surface desorption ionization by charged particles
US8835880B2 (en) * 2006-10-31 2014-09-16 Fei Company Charged particle-beam processing using a cluster source
JP5023886B2 (ja) * 2007-08-28 2012-09-12 株式会社島津製作所 大気圧maldi質量分析装置
US9144627B2 (en) 2007-09-14 2015-09-29 Exogenesis Corporation Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby
US11199769B2 (en) 2010-08-23 2021-12-14 Exogenesis Corporation Method and apparatus for neutral beam processing based on gas cluster ion beam technology
US10181402B2 (en) 2010-08-23 2019-01-15 Exogenesis Corporation Method and apparatus for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US10202684B2 (en) 2010-08-23 2019-02-12 Exogenesis Corporation Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US20170303383A1 (en) * 2010-08-23 2017-10-19 Exogenesis Corporation Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US10825685B2 (en) 2010-08-23 2020-11-03 Exogenesis Corporation Method for neutral beam processing based on gas cluster ion beam technology and articles produced thereby
US9799488B2 (en) * 2010-08-23 2017-10-24 Exogenesis Corporation Method and apparatus for neutral beam processing based on gas cluster ion beam technology
CN103180030B (zh) * 2010-08-23 2017-04-12 艾克索乔纳斯公司 基于气体团簇离子束技术的中性射束处理方法和设备
US10670960B2 (en) 2010-08-23 2020-06-02 Exogenesis Corporation Enhanced high aspect ratio etch performance using accelerated neutral beams derived from gas-cluster ion beams
US10556042B2 (en) 2011-08-19 2020-02-11 Exogenesis Corporation Drug delivery system and method of manufacturing thereof
CA2845762C (en) 2011-08-22 2019-01-08 Exogenesis Corporation Drug delivery system and method of manufacturing thereof
US9315798B2 (en) 2011-08-22 2016-04-19 Exogenesis Corporation Methods for improving the bioactivity characteristics of a surface and objects with surfaces improved thereby
EP3699950B1 (de) 2011-12-28 2026-01-28 Micromass UK Limited Kollisionsionengenerator und separator
JP5984424B2 (ja) * 2012-02-27 2016-09-06 国立大学法人京都大学 基板洗浄方法、基板洗浄装置及び真空処理装置
DE102012008259B4 (de) * 2012-04-25 2014-06-26 Bruker Daltonik Gmbh Ionenerzeugung in Massenspektrometern durch Clusterbeschuss
DE102012011648B4 (de) 2012-06-08 2018-06-14 Bruker Daltonik Gmbh Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie
DE102012011647B4 (de) 2012-06-08 2020-07-02 Bruker Daltonik Gmbh Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie
GB201307792D0 (en) * 2013-04-30 2013-06-12 Ionoptika Ltd Use of a water cluster ion beam for sample analysis
CA2977900A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Collision surface for improved ionisation
CA2978165A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Improved ionisation of gaseous samples
EP3264989B1 (de) 2015-03-06 2023-12-20 Micromass UK Limited Spektrometrische analyse
JP6800875B2 (ja) 2015-03-06 2020-12-16 マイクロマス ユーケー リミテッド 急速蒸発イオン化質量分析(「reims」)装置に連結されたイオンアナライザのための流入器具
US11037774B2 (en) 2015-03-06 2021-06-15 Micromass Uk Limited Physically guided rapid evaporative ionisation mass spectrometry (“REIMS”)
GB2551294B (en) 2015-03-06 2021-03-17 Micromass Ltd Liquid trap or separator for electrosurgical applications
US11031222B2 (en) 2015-03-06 2021-06-08 Micromass Uk Limited Chemically guided ambient ionisation mass spectrometry
US11139156B2 (en) * 2015-03-06 2021-10-05 Micromass Uk Limited In vivo endoscopic tissue identification tool
WO2016142691A1 (en) 2015-03-06 2016-09-15 Micromass Uk Limited Rapid evaporative ionisation mass spectrometry ("reims") and desorption electrospray ionisation mass spectrometry ("desi-ms") analysis of swabs and biopsy samples
US10978284B2 (en) 2015-03-06 2021-04-13 Micromass Uk Limited Imaging guided ambient ionisation mass spectrometry
GB2556436B (en) 2015-03-06 2022-01-26 Micromass Ltd Cell population analysis
GB2554206B (en) 2015-03-06 2021-03-24 Micromass Ltd Spectrometric analysis of microbes
CN107533032A (zh) 2015-03-06 2018-01-02 英国质谱公司 用于从块状组织直接映射的原位电离质谱测定成像平台
EP3265822B1 (de) 2015-03-06 2021-04-28 Micromass UK Limited Gewebeanalyse mittels massenspektrometrie oder ionenmobilitätsspektrometrie
GB201517195D0 (en) 2015-09-29 2015-11-11 Micromass Ltd Capacitively coupled reims technique and optically transparent counter electrode
WO2017178833A1 (en) 2016-04-14 2017-10-19 Micromass Uk Limited Spectrometric analysis of plants

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755344A (en) * 1980-04-11 1988-07-05 The United States Of America As Represented By The United States Department Of Energy Method and apparatus for the production of cluster ions
US4378499A (en) * 1981-03-31 1983-03-29 The Bendix Corporation Chemical conversion for ion mobility detectors using surface interactions
US5053343A (en) * 1985-02-15 1991-10-01 Environmental Technologies Group, Inc. Selective ionization of gas constituents using electrolytic reactions
IL81375A (en) * 1987-01-23 1990-11-05 Univ Ramot Method and apparatus for producing ions by surface ionization of energy-rich molecules and atoms
US4851669A (en) * 1988-06-02 1989-07-25 The Regents Of The University Of California Surface-induced dissociation for mass spectrometry
US4935623A (en) * 1989-06-08 1990-06-19 Hughes Aircraft Company Production of energetic atom beams
US5051582A (en) 1989-09-06 1991-09-24 The United States Of America As Represented By The Secretary Of The Air Force Method for the production of size, structure and composition of specific-cluster ions
US5239820A (en) 1991-11-18 1993-08-31 California Institute Of Technology Electric propulsion using C60 molecules
US5338931A (en) * 1992-04-23 1994-08-16 Environmental Technologies Group, Inc. Photoionization ion mobility spectrometer
US5780862A (en) * 1994-01-11 1998-07-14 Siess; Harold E. Method and apparatus for generating ions
US5577092A (en) * 1995-01-25 1996-11-19 Kublak; Glenn D. Cluster beam targets for laser plasma extreme ultraviolet and soft x-ray sources
DE19617011C2 (de) * 1996-04-27 2000-11-02 Bruker Daltonik Gmbh Matrixkomponentengemisch für die matrixunterstützte Laserdesorption und Ionisierung sowie Verfahren zur Zubereitung eines Matrixkomponentengemisches
US5767511A (en) * 1996-07-25 1998-06-16 Raytheon Company Mean cluster size determination using water capture

Also Published As

Publication number Publication date
EP1200984A2 (de) 2002-05-02
WO2001008196A3 (de) 2001-12-06
DE50011459D1 (de) 2005-12-01
WO2001008196A2 (de) 2001-02-01
JP2003505704A (ja) 2003-02-12
DE19934173A1 (de) 2001-01-25
EP1200984B1 (de) 2005-10-26
US7247845B1 (en) 2007-07-24

Similar Documents

Publication Publication Date Title
ATE308114T1 (de) Verfahren und vorrichtung zur clusterfragmentation
WO2004097369A3 (en) Fragmentation-based methods and systems for de novo sequencing
DE60329582D1 (de) Verfahren und vorrichtung zur cache-promotion
AU2002365508A1 (en) Apparatus and method for modification of magnetically immobilized biomolecules
AU3365095A (en) High throughput screening method for sequences or genetic alterations in nucleic acids
DE60011390D1 (de) Verfahren und vorrichtung zur identifikation oder karakterisierung von polypeptiden
EP1845460A3 (de) Verfahren und Vorrichtung zur Datenverarbeitung
DE60028732D1 (de) Verfahren zur erhaltung der dns-integrität
BR0214907A (pt) Método para fluoração de um artigo poroso, artigo, e, aparelho para fluoração de um substrato
DE60213803D1 (en) Happier mapping
DE59912351D1 (de) System und verfahren zur identifizierung und authentifizierung von zubehör, hilfs- und/oder betriebsstoffen für technische geräte
DE69940601D1 (de) Verfahren zur markierung von rns
EA200300495A1 (ru) Способ обработки скважины
ATE348204T1 (de) Verfahren zur gewinnung von lithium
EP1329938A3 (de) Ionenbestrahlungsgerät
DE69508617D1 (de) Vorrichtung zur dürchführung von magnetischen zyklusreactionen
NZ510873A (en) Characterising polypeptides through cleavage and mass spectrometry
MX2023014557A (es) Sistemas crispr-transposon para modificacion de adn.
PT98564A (pt) Processo para a realizacao de processos catalizados por enzimas com cristais reticulados como forma de imobilizacao de enzimas e dispositivos que os contem
EP0964425A3 (de) Apparat zur Bearbeitung eines Werkstücks mit einem gleichmässig neutralisierten Ionenstrahl
DE69940187D1 (de) Verfahren und Vorrichtung zur Übertragung von Ionen zwischen einer Atmosphärendruckionenquelle und einem Ionenfallenmassenspektrometer
AU2003211041A1 (en) Method and system for accelerating the conversion process between encryption schemes
ATE403864T1 (de) Verfahren zur identifizierung von substanzen, die die aktivität von hyperpolarisations-aktivierten kationen-kanälen modulieren
BR0114595A (pt) Uso de um composto que rompe esteróide sexual que sinaliza para o timo no tratamento de um distúrbio de células t
DE60124289D1 (de) Verfahren zur herstellung von 21-hydroxy-6,19-oxidoprogesteron (21oh-6op)

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee