ATE308553T1 - Nukleinsäurevermittelter elektronentransfer - Google Patents

Nukleinsäurevermittelter elektronentransfer

Info

Publication number
ATE308553T1
ATE308553T1 AT97928853T AT97928853T ATE308553T1 AT E308553 T1 ATE308553 T1 AT E308553T1 AT 97928853 T AT97928853 T AT 97928853T AT 97928853 T AT97928853 T AT 97928853T AT E308553 T1 ATE308553 T1 AT E308553T1
Authority
AT
Austria
Prior art keywords
nucleic acid
complexes
electron transfer
mediated electron
moieties
Prior art date
Application number
AT97928853T
Other languages
English (en)
Inventor
Thomas J Meade
Thomas W Welch
Original Assignee
Amersham Biosciences Sv Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amersham Biosciences Sv Corp filed Critical Amersham Biosciences Sv Corp
Application granted granted Critical
Publication of ATE308553T1 publication Critical patent/ATE308553T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT97928853T 1996-06-07 1997-06-04 Nukleinsäurevermittelter elektronentransfer ATE308553T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65998796A 1996-06-07 1996-06-07
PCT/US1997/009739 WO1997046568A1 (en) 1996-06-07 1997-06-04 Nucleic acid mediated electron transfer

Publications (1)

Publication Number Publication Date
ATE308553T1 true ATE308553T1 (de) 2005-11-15

Family

ID=24647650

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97928853T ATE308553T1 (de) 1996-06-07 1997-06-04 Nukleinsäurevermittelter elektronentransfer

Country Status (7)

Country Link
EP (1) EP0923595B1 (de)
JP (1) JP2000511904A (de)
AT (1) ATE308553T1 (de)
AU (1) AU738189B2 (de)
CA (1) CA2257534A1 (de)
DE (1) DE69734520D1 (de)
WO (1) WO1997046568A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
US5620850A (en) 1994-09-26 1997-04-15 President And Fellows Of Harvard College Molecular recognition at surfaces derivatized with self-assembled monolayers
US7381525B1 (en) 1997-03-07 2008-06-03 Clinical Micro Sensors, Inc. AC/DC voltage apparatus for detection of nucleic acids
US7014992B1 (en) 1996-11-05 2006-03-21 Clinical Micro Sensors, Inc. Conductive oligomers attached to electrodes and nucleoside analogs
AU1656299A (en) * 1997-12-16 1999-07-05 University Of Saskatchewan Conductive metal-containing nucleic acids
CA2229386A1 (en) * 1997-12-16 1999-06-16 The University Of Saskatchewan Conductive metal-containing nucleic acids
US7087148B1 (en) 1998-06-23 2006-08-08 Clinical Micro Sensors, Inc. Binding acceleration techniques for the detection of analytes
JP2002518998A (ja) * 1998-06-24 2002-07-02 セラセンス、インク. ヌクレオチドシーケンスの電気化学的認識用マルチセンサーアレイおよび方法
US6740518B1 (en) 1998-09-17 2004-05-25 Clinical Micro Sensors, Inc. Signal detection techniques for the detection of analytes
WO2000024941A1 (en) 1998-10-27 2000-05-04 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
US20020004593A1 (en) * 1998-11-13 2002-01-10 Thomas J. Meade Methods of making modified nucleosides
DE19964220C2 (de) 1998-11-23 2003-07-03 Friz Biochem Gmbh Verfahren zur Herstellung einer modifizierten leitfähigen Oberfläche
US7160869B2 (en) 1998-12-16 2007-01-09 University Of Saskatchewan Biologically active metal-containing nucleic acids
DE19901761A1 (de) * 1999-01-18 1999-07-01 Gerhard Dr Hartwich Verfahren zur elektrochemischen Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen
US7312087B2 (en) 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US20020177135A1 (en) 1999-07-27 2002-11-28 Doung Hau H. Devices and methods for biochip multiplexing
US6787339B1 (en) 2000-10-02 2004-09-07 Motorola, Inc. Microfluidic devices having embedded metal conductors and methods of fabricating said devices
WO2003018834A2 (de) 2001-08-25 2003-03-06 Friz Biochem Gmbh Verdrängungsassay zur detektion von nukleinsäureoligomer-hybridisierungsereignissen
EP2330407B1 (de) 2001-09-14 2013-05-29 ARKRAY, Inc. Verfahren, Werkzeug und Vorrichtung zur Messung der Konzentration
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
CA2651815A1 (en) 2006-05-10 2007-11-22 Dxterity Diagnostics Detection of nucleic acid targets using chemically reactive oligonucleotide probes
CA2757300C (en) 2009-04-01 2018-01-09 Dxterity Diagnostics Incorporated Chemical ligation dependent probe amplification (clpa)
US9745616B2 (en) 2011-05-17 2017-08-29 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
CN106879252B (zh) 2014-06-10 2020-07-17 德克斯特里蒂诊断公司 用于收集和稳定生物样品的装置及方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112974A (en) * 1985-01-18 1992-05-12 The Trustees Of Columbia University In The City Of New York Mixed ligand complexes and uses thereof as binding agents to DNA
JPS63238166A (ja) * 1987-03-26 1988-10-04 Mitsubishi Electric Corp 有機電子素子材料
CA2094785A1 (en) * 1992-05-08 1993-11-09 Jean Gariepy Metal chelating peptide
US5591578A (en) * 1993-12-10 1997-01-07 California Institute Of Technology Nucleic acid mediated electron transfer
DK0871773T3 (da) * 1995-06-27 2002-12-09 Univ North Carolina Elektrokemisk detektion af nukleinsyrehybridisering

Also Published As

Publication number Publication date
EP0923595B1 (de) 2005-11-02
AU3301497A (en) 1998-01-05
DE69734520D1 (de) 2005-12-08
EP0923595A1 (de) 1999-06-23
WO1997046568A1 (en) 1997-12-11
AU738189B2 (en) 2001-09-13
CA2257534A1 (en) 1997-12-11
JP2000511904A (ja) 2000-09-12

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Legal Events

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