ATE308755T1 - Pränatale diagnostische verfahren in vitro - Google Patents

Pränatale diagnostische verfahren in vitro

Info

Publication number
ATE308755T1
ATE308755T1 AT98908222T AT98908222T ATE308755T1 AT E308755 T1 ATE308755 T1 AT E308755T1 AT 98908222 T AT98908222 T AT 98908222T AT 98908222 T AT98908222 T AT 98908222T AT E308755 T1 ATE308755 T1 AT E308755T1
Authority
AT
Austria
Prior art keywords
embryonic
fetal
cells
blood cells
red blood
Prior art date
Application number
AT98908222T
Other languages
English (en)
Inventor
Ann Burchell
School Medical
Robert Hume
Original Assignee
Univ Dundee
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9704876.3A external-priority patent/GB9704876D0/en
Application filed by Univ Dundee filed Critical Univ Dundee
Application granted granted Critical
Publication of ATE308755T1 publication Critical patent/ATE308755T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Treatment Of Sludge (AREA)
  • Eye Examination Apparatus (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT98908222T 1997-03-08 1998-03-03 Pränatale diagnostische verfahren in vitro ATE308755T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9704876.3A GB9704876D0 (en) 1997-03-08 1997-03-08 Diagnostic methods
US6752097P 1997-12-04 1997-12-04
PCT/GB1998/000656 WO1998040746A1 (en) 1997-03-08 1998-03-03 Prenatal diagnostic methods

Publications (1)

Publication Number Publication Date
ATE308755T1 true ATE308755T1 (de) 2005-11-15

Family

ID=26311146

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908222T ATE308755T1 (de) 1997-03-08 1998-03-03 Pränatale diagnostische verfahren in vitro

Country Status (15)

Country Link
US (1) US6331395B1 (de)
EP (1) EP0974056B1 (de)
JP (1) JP2001514751A (de)
CN (1) CN1260046A (de)
AT (1) ATE308755T1 (de)
AU (1) AU738401B2 (de)
BR (1) BR9808219A (de)
CA (1) CA2283416A1 (de)
DE (1) DE69832161T2 (de)
DK (1) DK0974056T3 (de)
ES (1) ES2255150T3 (de)
GB (1) GB2326943B (de)
NO (1) NO994358D0 (de)
PL (1) PL335543A1 (de)
WO (1) WO1998040746A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000071987A2 (en) * 1999-05-25 2000-11-30 John Philip Isolation and culturing of fetal cells
GB0022017D0 (en) * 2000-09-08 2000-10-25 Univ Dundee Cell assays
EP1569510B1 (de) 2002-09-27 2011-11-02 The General Hospital Corporation Mikrofluidische vorrichtung zur zelltrennung und verwendungen davon
GB0415644D0 (en) * 2004-07-13 2004-08-18 Riverside Biosciences Ltd Monoclonal antibody
US20060105353A1 (en) * 2004-11-16 2006-05-18 Jalal Syed M Non-invasive prenatal fetal cell diagnostic method
US7439062B2 (en) * 2004-12-23 2008-10-21 Biocept, Inc. Beads for capturing target cells from bodily fluid
US20070196820A1 (en) 2005-04-05 2007-08-23 Ravi Kapur Devices and methods for enrichment and alteration of cells and other particles
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US8614419B2 (en) * 2008-03-28 2013-12-24 The Ohio State University Rapid diagnosis of a disease condition using infrared spectroscopy
CA2719489A1 (en) 2008-03-28 2009-10-01 The Ohio State University Rapid diagnosis of a disease condition using infrared spectroscopy
EP2526183A4 (de) 2010-01-21 2017-05-03 Biocep Ltd. Magnetische trennung seltener zellen
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
WO2016045022A1 (zh) * 2014-09-25 2016-03-31 深圳华大基因科技有限公司 用于孕妇外周血样的保存液和孕妇外周血样的保存方法
CN111948404B (zh) * 2020-08-03 2023-04-07 融智生物科技(青岛)有限公司 用于筛查地中海贫血的特征蛋白标记组合物、质谱模型及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641628A (en) * 1989-11-13 1997-06-24 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
WO1991007660A1 (en) * 1989-11-13 1991-05-30 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal dna
US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
DE4222573C1 (de) * 1992-05-16 1993-08-12 Dorothee Dr. 4400 Muenster De Ahlert
US5460942A (en) * 1993-09-10 1995-10-24 The United States Of America As Represented By The Department Of Health And Human Services The catalytic moiety of the glucose-6-phosphatase system: the gene and protein and related mutations
US5714325A (en) * 1993-09-24 1998-02-03 New England Medical Center Hospitals Prenatal diagnosis by isolation of fetal granulocytes from maternal blood
JPH10507632A (ja) * 1994-09-20 1998-07-28 ミルテニー バイオテック,インコーポレイティド 母体からの胎児血液の濃縮
GB9603249D0 (en) * 1996-02-16 1996-04-17 Univ Nottingham Foetal cell analysis
GB2313377B (en) * 1996-05-20 1998-07-01 Sumitomo Chemical Co Kit for diagnosis of hepatitis C and alcoholic cirrhosis
US5731156A (en) * 1996-10-21 1998-03-24 Applied Imaging, Inc. Use of anti-embryonic hemoglobin antibodies to identify fetal cells
US5859699A (en) 1997-02-07 1999-01-12 Arcturus Engineering, Inc. Laser capture microdissection analysis vessel

Also Published As

Publication number Publication date
JP2001514751A (ja) 2001-09-11
AU6630398A (en) 1998-09-29
EP0974056A1 (de) 2000-01-26
GB9820505D0 (en) 1998-11-11
DK0974056T3 (da) 2005-12-05
CA2283416A1 (en) 1998-09-17
NO994358L (no) 1999-09-08
DE69832161T2 (de) 2006-04-20
CN1260046A (zh) 2000-07-12
DE69832161D1 (de) 2005-12-08
US6331395B1 (en) 2001-12-18
NO994358D0 (no) 1999-09-08
BR9808219A (pt) 2000-05-16
AU738401B2 (en) 2001-09-20
GB2326943A (en) 1999-01-06
GB2326943B (en) 1999-06-16
ES2255150T3 (es) 2006-06-16
PL335543A1 (en) 2000-04-25
EP0974056B1 (de) 2005-11-02
WO1998040746A1 (en) 1998-09-17

Similar Documents

Publication Publication Date Title
DE69832161D1 (de) Pränatale diagnostische verfahren in vitro
AU4920097A (en) Use of anti-embryonic hemoglobin antibodies to identify fetal cells
Loewendorf et al. Normal human pregnancy results in maternal immune activation in the periphery and at the uteroplacental interface
ATE162631T1 (de) Ein nichtinvasives verfahren zur trennung und zum nachweis von fetaler dna
DE69633940D1 (de) Verfahren zur isolierung von zellen
ATE292282T1 (de) Verfahren zur zellseparation unter verwendung von immunorosetten
WO2007121276A3 (en) Enrichment of circulating fetal dna
ATE278803T1 (de) Verfahren zur überwachung der proteasomeinhibitorarzneimitteleffekte
ATE496288T1 (de) Gleichzeitige mehrfachanalyse klinischer proben
CA2140278A1 (en) Enriching and identyfing fetal cells in maternal blood for in situ hybridization
ATE354674T1 (de) Verfahren zur erkennung von transplantabstossungen
Clausen et al. Recommendation for validation and quality assurance of non‐invasive prenatal testing for foetal blood groups and implications for IVD risk classification according to EU regulations
DE59914830D1 (de) Verfahren und testbesteck zur beurteilung der oxid messung ihrer antiradikalen aktivität
ATE412896T1 (de) Pränatales down-syndrom-testverfahren unter benutzung von hyperglykosyliertem gonadotropin
Calabrese et al. Detection of chromosomal aneuploidies in fetal cells isolated from maternal blood using single‐chromosome dual‐probe FISH analysis
ATE163971T1 (de) Verfahren zur isolierung von fetalen zytotrophoblastzellen
PT1003458E (pt) Teste de funcao hepatica
NZ337700A (en) Prenatal diagnostic methods by separating maternal from fetal blood using conventional chromatographis techniques followed by typing fetal blood for genatic defects
DE69839876D1 (de) Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung
Voullaire et al. Fetal nucleated red blood cells from CVS washings: an aid to development of first trimester non‐invasive prenatal diagnosis
ES2169146T3 (es) Iniciadores y sondas destinadas para la amplificacion y para la deteccion del acido nucleico del citomegalovirus.
ATE179522T1 (de) Verfahren und mittel zum nachweis von krankheitszuständen aus änderungen im östrogenstoffwechsel
Quarta1ABCDEFG et al. Multiparameter flow cytometry characterization of MHC class I negative mouse bone marrow cells
CA2068660A1 (en) Non-invasive method for isolation and detection of fetal dna

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0974056

Country of ref document: EP

REN Ceased due to non-payment of the annual fee