ATE310524T1 - Modulatoren der methylierung zur kontrolle von bakterieller virulenz - Google Patents

Modulatoren der methylierung zur kontrolle von bakterieller virulenz

Info

Publication number
ATE310524T1
ATE310524T1 AT00939727T AT00939727T ATE310524T1 AT E310524 T1 ATE310524 T1 AT E310524T1 AT 00939727 T AT00939727 T AT 00939727T AT 00939727 T AT00939727 T AT 00939727T AT E310524 T1 ATE310524 T1 AT E310524T1
Authority
AT
Austria
Prior art keywords
methylation
modulators
bacterial virulence
controlling bacterial
virulence
Prior art date
Application number
AT00939727T
Other languages
English (en)
Inventor
Mingxu Xu
Qinghong Han
Yuying Tan
Original Assignee
Anticancer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anticancer Inc filed Critical Anticancer Inc
Application granted granted Critical
Publication of ATE310524T1 publication Critical patent/ATE310524T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Cookers (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT00939727T 1999-06-09 2000-06-09 Modulatoren der methylierung zur kontrolle von bakterieller virulenz ATE310524T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13830799P 1999-06-09 1999-06-09
PCT/US2000/015865 WO2000074686A1 (en) 1999-06-09 2000-06-09 Modulators of methylation for control of bacterial virulence

Publications (1)

Publication Number Publication Date
ATE310524T1 true ATE310524T1 (de) 2005-12-15

Family

ID=22481445

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00939727T ATE310524T1 (de) 1999-06-09 2000-06-09 Modulatoren der methylierung zur kontrolle von bakterieller virulenz

Country Status (8)

Country Link
US (1) US6632430B2 (de)
EP (1) EP1183034B1 (de)
JP (1) JP2003501391A (de)
AT (1) ATE310524T1 (de)
AU (1) AU784794B2 (de)
CA (1) CA2375383C (de)
DE (1) DE60024257T2 (de)
WO (1) WO2000074686A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026155B2 (en) * 1999-02-02 2006-04-11 Regents Of The University Of California Method of reducing bacterial proliferation
ATE531813T1 (de) * 2001-12-31 2011-11-15 Anticancer Inc System zur überwachung einer bakteriellen tumorbehandlung
US7264819B2 (en) * 2003-06-23 2007-09-04 Anticancer, Inc. Lyase treatment for P. carinii
US9200251B1 (en) 2011-03-31 2015-12-01 David Gordon Bermudes Bacterial methionine analogue and methionine synthesis inhibitor anticancer, antiinfective and coronary heart disease protective microcins and methods of treatment therewith

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455727A (en) 1977-10-07 1979-05-04 Sankyo Co Ltd Method for preventing growth of mold
US4381004A (en) 1981-01-15 1983-04-26 Biomedics, Inc. Extracorporeal system for treatment of infectious and parasitic diseases
US4507287A (en) 1983-06-20 1985-03-26 Dixon Glen J Preparation and method for the treatment of acne
US4996308A (en) * 1988-03-25 1991-02-26 Merrell Dow Pharmaceuticals Inc. Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group
ZA894534B (en) * 1988-06-20 1990-03-28 Merrell Dow Pharma Novel neplanocin derivatives
HU204843B (en) * 1988-09-27 1992-02-28 Merrell Dow Pharma Process for producing 2'-halogen-methylidene adenosine derivatives and pharmaceutical compositions comprising same
US6001840A (en) 1990-03-06 1999-12-14 Southern Research Institute Methods of treatment of viral infections using carbocyclic deoxyguanosine analogs
US5872104A (en) * 1994-12-27 1999-02-16 Oridigm Corporation Combinations and methods for reducing antimicrobial resistance

Also Published As

Publication number Publication date
US6632430B2 (en) 2003-10-14
CA2375383A1 (en) 2000-12-14
WO2000074686A1 (en) 2000-12-14
JP2003501391A (ja) 2003-01-14
AU784794B2 (en) 2006-06-22
DE60024257T2 (de) 2006-07-20
EP1183034B1 (de) 2005-11-23
EP1183034A1 (de) 2002-03-06
US20030138414A1 (en) 2003-07-24
CA2375383C (en) 2008-07-29
DE60024257D1 (de) 2005-12-29
AU5476900A (en) 2000-12-28

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Legal Events

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