ATE310840T1 - Verfahren zur herstellung von seidenfibroinvliesstoffen - Google Patents

Verfahren zur herstellung von seidenfibroinvliesstoffen

Info

Publication number
ATE310840T1
ATE310840T1 AT01976631T AT01976631T ATE310840T1 AT E310840 T1 ATE310840 T1 AT E310840T1 AT 01976631 T AT01976631 T AT 01976631T AT 01976631 T AT01976631 T AT 01976631T AT E310840 T1 ATE310840 T1 AT E310840T1
Authority
AT
Austria
Prior art keywords
silk
silk fibroin
nonwoven fabrics
kda
producing silk
Prior art date
Application number
AT01976631T
Other languages
English (en)
Inventor
Ubaldo Armato
Pra Ilaria Dal
Kemal Kesenci
Claudio Migliaresi
Antonella Motta
Original Assignee
Consorzio Per Gli Studi Uni
Ubaldo Armato
Pra Ilaria Dal
Kemal Kesenci
Claudio Migliaresi
Antonella Motta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consorzio Per Gli Studi Uni, Ubaldo Armato, Pra Ilaria Dal, Kemal Kesenci, Claudio Migliaresi, Antonella Motta filed Critical Consorzio Per Gli Studi Uni
Application granted granted Critical
Publication of ATE310840T1 publication Critical patent/ATE310840T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225—Fibrin; Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01D—MECHANICAL METHODS OR APPARATUS IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS
    • D01D5/00—Formation of filaments, threads, or the like
    • D01D5/40—Formation of filaments, threads, or the like by applying a shearing force to a dispersion or solution of filament formable polymers, e.g. by stirring
    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • D01F4/02—Monocomponent artificial filaments or the like of proteins; Manufacture thereof from fibroin
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H1/00—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres
    • D04H1/40—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties
    • D04H1/42—Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties characterised by the use of certain kinds of fibres insofar as this use has no preponderant influence on the consolidation of the fleece
    • D04H1/4266—Natural fibres not provided for in group D04H1/425
    • D—TEXTILES; PAPER
    • D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
    • D04H—MAKING TEXTILE FABRICS, e.g. FROM FIBRES OR FILAMENTARY MATERIAL; FABRICS MADE BY SUCH PROCESSES OR APPARATUS, e.g. FELTS, NON-WOVEN FABRICS; COTTON-WOOL; WADDING ; NON-WOVEN FABRICS FROM STAPLE FIBRES, FILAMENTS OR YARNS, BONDED WITH AT LEAST ONE WEB-LIKE MATERIAL DURING THEIR CONSOLIDATION
    • D04H3/00—Non-woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length
    • D04H3/015—Natural yarns or filaments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Textile Engineering (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Mechanical Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Artificial Filaments (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Woven Fabrics (AREA)
AT01976631T 2000-10-02 2001-09-28 Verfahren zur herstellung von seidenfibroinvliesstoffen ATE310840T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000VR000096A IT1316885B1 (it) 2000-10-02 2000-10-02 Procedimento per la preparazione di un tessuto non tessuto in fibroinadi seta.
PCT/IT2001/000501 WO2002029141A1 (en) 2000-10-02 2001-09-28 Method for the preparation of a non-woven silk fibroin fabrics

Publications (1)

Publication Number Publication Date
ATE310840T1 true ATE310840T1 (de) 2005-12-15

Family

ID=11461889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01976631T ATE310840T1 (de) 2000-10-02 2001-09-28 Verfahren zur herstellung von seidenfibroinvliesstoffen

Country Status (8)

Country Link
US (1) US7285637B2 (de)
EP (1) EP1327014B1 (de)
AT (1) ATE310840T1 (de)
AU (1) AU2001295891A1 (de)
DE (1) DE60115271T2 (de)
ES (1) ES2254500T3 (de)
IT (1) IT1316885B1 (de)
WO (1) WO2002029141A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002367580A1 (en) * 2001-05-16 2003-09-22 Tracy C. Grikscheit Tissue-engineered organs
ES2321915T3 (es) 2001-10-25 2009-06-15 University Of Connecticut Composiciones de fibroina y metodos para preparar las mismas.
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
US20110009960A1 (en) * 2001-11-16 2011-01-13 Allergan, Inc. Prosthetic fabric structure
JP2005515309A (ja) * 2002-01-09 2005-05-26 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー ポリペプチド繊維およびそれらの製造方法
WO2004000915A2 (en) * 2002-06-24 2003-12-31 Tufts University Silk biomaterials and methods of use thereof
US7842780B2 (en) 2003-01-07 2010-11-30 Trustees Of Tufts College Silk fibroin materials and use thereof
PT2426241E (pt) * 2003-03-11 2013-08-30 Allergan Inc Dispositivos médicos à base de fibras de seda imunoneutras
EP3231846A1 (de) 2003-04-10 2017-10-18 Tufts University Konzentrierte wässrige seidenfibroinlösung und verwendung davon
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
CA2608862C (en) 2004-06-11 2020-05-05 Trustees Of Tufts College Silk-based drug delivery system
KR100762928B1 (ko) 2004-10-29 2007-10-04 재단법인서울대학교산학협력재단 견 피브로인 나노섬유로 이루어진 부직포 형태의 골조직유도 재생용 차폐막 및 그 제조방법
JP2010522583A (ja) 2007-02-27 2010-07-08 トラスティーズ オブ タフツ カレッジ 組織工学的に作製された絹製臓器
CA2682701A1 (en) 2007-03-20 2008-09-25 Serica Technologies, Inc. Prosthetic device and method of manufacturing the same
EA019118B1 (ru) 2007-05-29 2014-01-30 Трастиз Оф Тафтс Колледж Способ желатинизации фиброина шелка и регулирования времени желатинизации, способ инкапсуляции по меньшей мере одного компонента в фиброин шелка (варианты)
WO2009100280A2 (en) * 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
GB0807868D0 (en) 2008-04-30 2008-06-04 Knight David P Cartilage repair material and a method for the preparation thereof
WO2009140588A1 (en) * 2008-05-15 2009-11-19 Trustees Of Tufts College Silk polymer-based adenosine release: therapeutic potential for epilepsy
US8501172B2 (en) * 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
MX2011003618A (es) 2008-10-09 2011-06-16 Tufts College Peliculas de seda modificadas que contienen glicerol.
US9308070B2 (en) * 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
US9326840B2 (en) 2008-12-15 2016-05-03 Allergan, Inc. Prosthetic device and method of manufacturing the same
CN105063875A (zh) 2008-12-15 2015-11-18 阿勒根公司 制造用于假体装置的编织网的方法
US9204953B2 (en) 2008-12-15 2015-12-08 Allergan, Inc. Biocompatible surgical scaffold with varying stretch
US9204954B2 (en) 2008-12-15 2015-12-08 Allergan, Inc. Knitted scaffold with diagonal yarn
WO2011008842A2 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
CA2773956A1 (en) * 2009-09-11 2011-03-17 Allergan, Inc. Prosthetic device and method of manufacturing the same
JP2013506058A (ja) 2009-09-28 2013-02-21 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 延伸したシルクｅｇｅｌ繊維およびその製造方法
IN2012DN02358A (de) 2009-09-29 2015-08-21 Tufts College
US9603971B2 (en) 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
US8309689B2 (en) 2010-05-20 2012-11-13 Taipei Medical University High yield dialysis-free process for producing organosoluble regenerated silk fibroin
JP6081358B2 (ja) 2010-09-01 2017-02-15 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 絹フィブロインおよびポリエチレングリコールをベースとする生体材料
EP4218891A1 (de) 2010-10-19 2023-08-02 Trustees Of Tufts College Mikronadeln auf seidenfibroinbasis und verfahren zur herstellung davon
US10335519B2 (en) 2011-04-20 2019-07-02 Trustees Of Tufts College Dynamic silk coatings for implantable devices
ES2856873T3 (es) 2012-02-06 2021-09-28 Childrens Medical Center Biomaterial multicapa para la regeneración de tejidos y la cicatrización de las heridas
WO2013152265A1 (en) * 2012-04-06 2013-10-10 Trustees Of Tufts College Methods of producing and using silk microfibers
KR101313898B1 (ko) 2012-04-27 2013-09-30 서울대학교산학협력단 히알루론산―도파민 컨쥬게이트로 표면이 개질된 하이드록시아파타이트 나노입자를 포함하는 실크피브로인 나노섬유 및 이를 이용한 지지체
EP2712955A1 (de) 2012-09-27 2014-04-02 Ludwig Boltzmann Gesellschaft GmbH Produkt aus Seide
CN103446623B (zh) * 2013-09-18 2015-03-11 中国人民解放军军事医学科学院卫生装备研究所 一种组织工程表皮模型的构建方法
CN103668782B (zh) * 2013-11-29 2016-05-11 温州医科大学 超薄多孔复合纳米纤维仿生Bruch’s膜的静电纺丝制备方法
KR101573838B1 (ko) * 2014-06-13 2015-12-07 대한민국 누에고치를 이용한 인공 생체막 및 이의 제조방법
KR101714545B1 (ko) * 2014-06-26 2017-03-15 대한민국 골조직 형성 촉진용 차폐막의 제조방법 및 이를 이용하여 제조된 골조직 형성 촉진용 차폐막
KR101570717B1 (ko) 2014-08-04 2015-11-24 대한민국 누에고치를 이용한 치과용 차폐막 및 이의 제조방법
US9394355B2 (en) 2014-08-20 2016-07-19 Silk Technologies, Ltd. Fibroin-derived protein composition
US10611888B2 (en) 2015-04-23 2020-04-07 Rowan University Processes of increasing crystallinity alignment of protein films and products thereof
CN109069698B (zh) * 2016-03-31 2022-03-29 澳大利亚耳科学研究所 改善的丝纤蛋白甘油膜
WO2018006037A1 (en) * 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
AU2017310520A1 (en) 2016-08-12 2019-03-21 Silk Technologies, Ltd. Silk-derived protein for treating inflammation
WO2018195048A1 (en) * 2017-04-17 2018-10-25 Rowan University Solution blow spun protein-based polymer fibers and products comprising same
US20200188178A1 (en) * 2018-12-18 2020-06-18 National Taiwan University Of Science And Technology Double-layer dressing containing silk fibroin and a method for making the same
US12615142B2 (en) * 2021-02-03 2026-04-28 Gwangju Institute Of Science And Technology PUF ID and PUF ID reader
CN116392636A (zh) * 2023-03-29 2023-07-07 深圳高性能医疗器械国家研究院有限公司 蚕丝修复补片及其制备方法
CN116712612B (zh) * 2023-07-13 2025-08-26 上海市肺科医院（上海市职业病防治院） 一种具有微环境调节功能的组织工程仿生气管支架及其制备方法

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US976977A (en) 1908-11-27 1910-11-29 Carl Rudolf Baumann Process for obtaining silk fibroin.
US5171505A (en) * 1990-11-28 1992-12-15 E. I. Du Pont De Nemours And Company Process for spinning polypeptide fibers
DE19841649A1 (de) 1998-09-11 2000-04-27 Thueringisches Inst Textil Verfahren zur Herstellung und produktorientierten Verarbeitung von konzentrierten Lösungen fibrillärer Proteine in NMMNO-Monohydrat

Also Published As

Publication number Publication date
ITVR20000096A1 (it) 2002-04-02
ITVR20000096A0 (it) 2000-10-02
DE60115271T2 (de) 2006-08-24
EP1327014A1 (de) 2003-07-16
US20040097709A1 (en) 2004-05-20
IT1316885B1 (it) 2003-05-13
US7285637B2 (en) 2007-10-23
WO2002029141A1 (en) 2002-04-11
ES2254500T3 (es) 2006-06-16
DE60115271D1 (de) 2005-12-29
AU2001295891A1 (en) 2002-04-15
EP1327014B1 (de) 2005-11-23

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