ATE311183T1 - Enalaprilmaleat enthaltende, stabile, feste arzneimittel - Google Patents

Enalaprilmaleat enthaltende, stabile, feste arzneimittel

Info

Publication number: ATE311183T1
Authority: AT; Austria
Prior art keywords: stable; enalaprilmaleate; products containing; medicinal products; solid medicinal
Prior art date: 1999-05-03

Application number

AT00920968T

Other languages

English (en)

Inventor

Indu Bhushan

Jitendra K Somani

Original Assignee

Ranbaxy Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-03

Filing date

2000-05-03

Publication date

2005-12-15

1999-05-03 Priority claimed from US09/304,413 external-priority patent/US6296871B1/en

2000-05-03 Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE311183T1 publication Critical patent/ATE311183T1/de

Links

108010061435 Enalapril Proteins 0.000 title abstract 2
229960000309 enalapril maleate Drugs 0.000 title abstract 2
OYFJQPXVCSSHAI-QFPUQLAESA-N enalapril maleate Chemical compound OC(=O)\C=C/C(O)=O.C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 OYFJQPXVCSSHAI-QFPUQLAESA-N 0.000 title abstract 2
239000007787 solid Substances 0.000 title abstract 2
229940126601 medicinal product Drugs 0.000 title 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 2
OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
239000011976 maleic acid Substances 0.000 abstract 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid group Chemical group C(\C=C/C(=O)O)(=O)O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Inorganic Chemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT00920968T 1999-05-03 2000-05-03 Enalaprilmaleat enthaltende, stabile, feste arzneimittel ATE311183T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US09/304,413 US6296871B1 (en)	1998-04-12	1999-05-03	Stable solid pharmaceutical compositions containing enalapril maleate
PCT/IB2000/000569 WO2000066116A2 (en)	1999-05-03	2000-05-03	Stable solid pharmaceutical compositions containing enalapril maleate

Publications (1)

Publication Number	Publication Date
ATE311183T1 true ATE311183T1 (de)	2005-12-15

Family

ID=23176416

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00920968T ATE311183T1 (de)	1999-05-03	2000-05-03	Enalaprilmaleat enthaltende, stabile, feste arzneimittel

Country Status (6)

Country	Link
EP (1)	EP1178793B1 (de)
AT (1)	ATE311183T1 (de)
AU (1)	AU4137300A (de)
DE (1)	DE60024439D1 (de)
MY (1)	MY121470A (de)
WO (1)	WO2000066116A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001019348A1 (en) *	1999-09-17	2001-03-22	Mylan Pharmaceuticals Inc.	Stabilization of enalapril maleate with maleic acid
WO2012085249A2 (en) *	2010-12-24	2012-06-28	Krka, D.D., Novo Mesto	Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts
PH12013501442B1 (en)	2011-01-07	2018-04-20	Novartis Ag	Immunosuppressant formulations
CN104984317A (zh) *	2015-07-20	2015-10-21	广州帝奇医药技术有限公司	含有依那普利的药物组合物及其制备方法
CL2024001316A1 (es) *	2024-04-29	2025-04-25	Laboratorios Andromaco S A	Composición farmacéutica que comprende enalapril maleato, uso y proceso de preparación.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4743450A (en) *	1987-02-24	1988-05-10	Warner-Lambert Company	Stabilized compositions
CA2128199C (en) *	1994-07-15	1997-02-04	Bernard Charles Sherman	Stable solid pharmaceutical compositions containing enalapril maleate
IT1282650B1 (it) *	1996-02-19	1998-03-31	Jagotec Ag	Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
HU222497B1 (hu) *	1996-12-18	2003-07-28	Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt.	Enalapril-maleátot tartalmazó stabilizált gyógyszerkészítmény és eljárás előállítására

2000
- 2000-05-02 MY MYPI20001881A patent/MY121470A/en unknown
- 2000-05-03 AU AU41373/00A patent/AU4137300A/en not_active Abandoned
- 2000-05-03 WO PCT/IB2000/000569 patent/WO2000066116A2/en not_active Ceased
- 2000-05-03 EP EP00920968A patent/EP1178793B1/de not_active Expired - Lifetime
- 2000-05-03 AT AT00920968T patent/ATE311183T1/de not_active IP Right Cessation
- 2000-05-03 DE DE60024439T patent/DE60024439D1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1178793A2 (de)	2002-02-13
WO2000066116A2 (en)	2000-11-09
AU4137300A (en)	2000-11-17
EP1178793B1 (de)	2005-11-30
DE60024439D1 (de)	2006-01-05
WO2000066116A3 (en)	2001-06-28
MY121470A (en)	2006-01-28

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Legal Events

Date	Code	Title	Description
2006-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties