ATE311382T1 - Verfahren zur herstellung von 2-carbamoyl- pyridinen - Google Patents

Verfahren zur herstellung von 2-carbamoyl- pyridinen

Info

Publication number
ATE311382T1
ATE311382T1 AT99114893T AT99114893T ATE311382T1 AT E311382 T1 ATE311382 T1 AT E311382T1 AT 99114893 T AT99114893 T AT 99114893T AT 99114893 T AT99114893 T AT 99114893T AT E311382 T1 ATE311382 T1 AT E311382T1
Authority
AT
Austria
Prior art keywords
pyridines
carbamoyl
producing
carbamoylation
concerned
Prior art date
Application number
AT99114893T
Other languages
English (en)
Inventor
Uwe Klinkhammer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE311382T1 publication Critical patent/ATE311382T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT99114893T 1998-08-10 1999-07-30 Verfahren zur herstellung von 2-carbamoyl- pyridinen ATE311382T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98114978 1998-08-10

Publications (1)

Publication Number Publication Date
ATE311382T1 true ATE311382T1 (de) 2005-12-15

Family

ID=8232437

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99114893T ATE311382T1 (de) 1998-08-10 1999-07-30 Verfahren zur herstellung von 2-carbamoyl- pyridinen

Country Status (10)

Country Link
US (1) US6103902A (de)
EP (1) EP0979822B1 (de)
JP (1) JP3344972B2 (de)
KR (1) KR100362081B1 (de)
CN (1) CN1117746C (de)
AT (1) ATE311382T1 (de)
CA (1) CA2279796C (de)
DE (1) DE69928610T2 (de)
DK (1) DK0979822T3 (de)
ES (1) ES2252894T3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6670362B2 (en) 2000-09-20 2003-12-30 Pfizer Inc. Pyridazine endothelin antagonists
CN107531677A (zh) * 2015-02-25 2018-01-02 法尔玛赞公司 用于制备托匹司他及其中间体的方法
CN105669542A (zh) * 2016-03-08 2016-06-15 南京师范大学 一种直接催化氧化法合成吡啶伯酰胺化合物的方法
CA3197265A1 (en) * 2020-11-05 2022-05-12 Timo Rager A stable crystalline hydrate of clazosentan disodium salt
EP4582086A3 (de) * 2021-12-17 2025-07-23 Idorsia Pharmaceuticals Ltd Clazosentan-dinatriumsalz, dessen herstellung und pharmazeutische zusammensetzungen damit

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW313568B (de) * 1994-12-20 1997-08-21 Hoffmann La Roche

Also Published As

Publication number Publication date
JP3344972B2 (ja) 2002-11-18
US6103902A (en) 2000-08-15
CN1117746C (zh) 2003-08-13
CA2279796C (en) 2003-09-30
KR100362081B1 (ko) 2002-11-23
JP2000063377A (ja) 2000-02-29
ES2252894T3 (es) 2006-05-16
CA2279796A1 (en) 2000-02-10
DE69928610T2 (de) 2006-08-10
KR20000017194A (ko) 2000-03-25
EP0979822B1 (de) 2005-11-30
CN1245803A (zh) 2000-03-01
DK0979822T3 (da) 2006-03-27
EP0979822A1 (de) 2000-02-16
DE69928610D1 (de) 2006-01-05

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