ATE311877T1 - Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion - Google Patents

Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion

Info

Publication number: ATE311877T1
Authority: AT; Austria
Prior art keywords: production; apoprotein; inhibitors; reducing agents; lower alkylene
Prior art date: 1998-02-24

Application number

AT99905282T

Other languages

English (en)

Inventor

Akira Yamamoto

Original Assignee

Taiho Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-24

Filing date

1999-02-23

Publication date

2005-12-15

1999-02-23 Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd

2005-12-15 Application granted granted Critical

2005-12-15 Publication of ATE311877T1 publication Critical patent/ATE311877T1/de

Links

239000003112 inhibitor Substances 0.000 title abstract 2
108010012927 Apoprotein(a) Proteins 0.000 title 1
239000003638 chemical reducing agent Substances 0.000 title 1
125000002947 alkylene group Chemical group 0.000 abstract 3
102100040214 Apolipoprotein(a) Human genes 0.000 abstract 2
101710115418 Apolipoprotein(a) Proteins 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
125000004450 alkenylene group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000005529 alkyleneoxy group Chemical group 0.000 abstract 1
WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical class OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)

AT99905282T 1998-02-24 1999-02-23 Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion ATE311877T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP4200498		1998-02-24
PCT/JP1999/000798 WO1999043318A1 (en)	1998-02-24	1999-02-23	Lp(a)-LOWERING AGENTS AND APOPROTEIN (a) PRODUCTION INHIBTORS

Publications (1)

Publication Number	Publication Date
ATE311877T1 true ATE311877T1 (de)	2005-12-15

Family

ID=12624057

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99905282T ATE311877T1 (de)	1998-02-24	1999-02-23	Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion

Country Status (7)

Country	Link
US (1)	US6166036A (de)
EP (1)	EP1000620B1 (de)
JP (1)	JP3412829B2 (de)
AT (1)	ATE311877T1 (de)
DE (1)	DE69928749T2 (de)
ES (1)	ES2255245T3 (de)
WO (1)	WO1999043318A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR101943676B1 (ko)	2011-06-28	2019-01-29	메르크 파텐트 게엠베하	금속 착물
KR101903216B1 (ko)	2011-10-20	2018-10-01	메르크 파텐트 게엠베하	유기 전계발광 소자용 재료
JPWO2015186747A1 (ja) *	2014-06-04	2017-07-13	元夫通	４−置換安息香酸誘導体の固体分散体、その製造方法およびそれを含む医薬組成物
US20180318279A1 (en) *	2015-10-23	2018-11-08	Rush University Medical Center	Topical compositions providing pain relief and methods of use thereof
TW202509024A (zh) *	2023-05-19	2025-03-01	大陸商深圳信立泰藥業股份有限公司	一種磺醯胺類化合物及其製備方法和醫藥用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5231184A (en) *	1987-11-23	1993-07-27	Janssen Pharmaceutica N.V.	Pridazinamine derivatives
ES2087097T3 (es) *	1989-04-19	1996-07-16	Otsuka Pharma Co Ltd	Derivados de acidos fenilcarboxilicos que contienen un heterociclo.
JPH04112868A (ja) *	1990-09-03	1992-04-14	Otsuka Pharmaceut Co Ltd	置換ヘテロ環を有するフェニルカルボン酸誘導体
CA2122705C (en) *	1992-09-11	1997-11-18	Taiho Pharmaceutical Co., Ltd.	Optically active 1-phenylpyrrolidone derivative, intermediate for producing the same, and process for producing both

1999
- 1999-02-23 DE DE69928749T patent/DE69928749T2/de not_active Expired - Fee Related
- 1999-02-23 WO PCT/JP1999/000798 patent/WO1999043318A1/ja not_active Ceased
- 1999-02-23 US US09/403,495 patent/US6166036A/en not_active Expired - Fee Related
- 1999-02-23 JP JP54339299A patent/JP3412829B2/ja not_active Expired - Fee Related
- 1999-02-23 AT AT99905282T patent/ATE311877T1/de not_active IP Right Cessation
- 1999-02-23 ES ES99905282T patent/ES2255245T3/es not_active Expired - Lifetime
- 1999-02-23 EP EP99905282A patent/EP1000620B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69928749D1 (de)	2006-01-12
DE69928749T2 (de)	2006-06-29
EP1000620A1 (de)	2000-05-17
JP3412829B2 (ja)	2003-06-03
ES2255245T3 (es)	2006-06-16
EP1000620B1 (de)	2005-12-07
EP1000620A4 (de)	2004-03-17
US6166036A (en)	2000-12-26
WO1999043318A1 (en)	1999-09-02

Legal Events

Date	Code	Title	Description
2006-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
PT976748E (pt)	2004-03-31	Derivados de pirrolidina com actividade inibidora de fosfolipase a2
DE60315265D1 (de)	2007-09-13	Stickstoffhaltige heterocyclische verbindung und arzneimittel davon
ATE537158T1 (de)	2011-12-15	M-stage-kinesin-inhibitor
PT928788E (pt)	2003-04-30	Compostos farmaceuticamente activos
IL124944A (en)	2003-06-24	Quinolonecarboxylic acid derivatives or their salts and pharmaceutical compositions containing them
DE69813605D1 (de)	2003-05-22	Benzofuranderivate
ATE271045T1 (de)	2004-07-15	Sauerstoffhaltige heterocyclische verbindungen
ATE252074T1 (de)	2003-11-15	Phenylalkylcarbonsäure-derivate
DE60223904D1 (de)	2008-01-17	Benzylaminanalogen
KR920701240A (ko)	1992-08-11	글루타티온 유도체
EP0801065A4 (de)	1998-02-25	1,4-dihydropyridinverbindungen und sie enthaltende medizinische zusammensetzungen
ATE311877T1 (de)	2005-12-15	Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion
ATE174593T1 (de)	1999-01-15	Neue bisoxadiazolidinderivate
MX9206930A (es)	1993-06-01	Nuevos compuestos
EP0680960A4 (de)	1997-05-14	Imidazolverbindung.
ATE171622T1 (de)	1998-10-15	Antiallergische zusammensetzung enthaltend eine phosphorsäurediester-verbindung
EP0982029A4 (de)	2002-07-03	Vorbeugende /heilmittel fuer arteriosklerose
IL151880A0 (en)	2003-04-10	Triazole derivatives and pharmaceutical compositions containing the same
ATE251632T1 (de)	2003-10-15	Phosphonsäure-diester-derivate
ES2111637T3 (es)	1998-03-16	Derivado de benzotiadiazina.
DE69837628D1 (de)	2007-05-31	Aminderivate, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel
DE60238847D1 (de)	2011-02-17	Pyrimidinderivate enthaltendes medikament