ATE312349T1 - Differentielle diagnose von neurodegeneration - Google Patents
Differentielle diagnose von neurodegenerationInfo
- Publication number
- ATE312349T1 ATE312349T1 AT99934543T AT99934543T ATE312349T1 AT E312349 T1 ATE312349 T1 AT E312349T1 AT 99934543 T AT99934543 T AT 99934543T AT 99934543 T AT99934543 T AT 99934543T AT E312349 T1 ATE312349 T1 AT E312349T1
- Authority
- AT
- Austria
- Prior art keywords
- neurodegeneration
- differential diagnosis
- methods
- quantification
- relates
- Prior art date
Links
- 230000004770 neurodegeneration Effects 0.000 title abstract 4
- 238000003748 differential diagnosis Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000003556 assay Methods 0.000 abstract 2
- 230000000926 neurological effect Effects 0.000 abstract 2
- 238000011002 quantification Methods 0.000 abstract 2
- 238000011895 specific detection Methods 0.000 abstract 2
- 101150004420 RAB3A gene Proteins 0.000 abstract 1
- 108010057722 Synaptosomal-Associated Protein 25 Proteins 0.000 abstract 1
- 102000004183 Synaptosomal-Associated Protein 25 Human genes 0.000 abstract 1
- 102000003802 alpha-Synuclein Human genes 0.000 abstract 1
- 108090000185 alpha-Synuclein Proteins 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 abstract 1
- 239000013068 control sample Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Eye Examination Apparatus (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98870148 | 1998-07-03 | ||
| EP98870236 | 1998-11-03 | ||
| EP99870069 | 1999-04-09 | ||
| PCT/EP1999/004483 WO2000002053A2 (en) | 1998-07-03 | 1999-06-29 | Differential diagnosis of neurodegeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312349T1 true ATE312349T1 (de) | 2005-12-15 |
Family
ID=27239769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99934543T ATE312349T1 (de) | 1998-07-03 | 1999-06-29 | Differentielle diagnose von neurodegeneration |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1095278B1 (de) |
| JP (3) | JP2002519702A (de) |
| CN (1) | CN1316055A (de) |
| AT (1) | ATE312349T1 (de) |
| AU (1) | AU754062B2 (de) |
| BR (1) | BR9911291A (de) |
| CA (1) | CA2329523A1 (de) |
| DE (1) | DE69928809T2 (de) |
| DK (1) | DK1095278T3 (de) |
| ES (1) | ES2255280T3 (de) |
| WO (1) | WO2000002053A2 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| AU2002256677A1 (en) * | 2001-03-15 | 2002-10-03 | Novartis Ag | Screening for drugs against disorders associated with schizophrenia |
| EP1451217A4 (de) * | 2001-11-20 | 2005-10-12 | Atgen Co Ltd | Neue peptide, die resistenz gegen umweltstress verleihen, und diese peptide enthaltende fusionsproteine |
| GB0203446D0 (en) * | 2002-02-14 | 2002-04-03 | Univ Lancaster | Detection and/or monitoring of synuclein-related diseases |
| US9034337B2 (en) | 2003-10-31 | 2015-05-19 | Prothena Biosciences Limited | Treatment and delay of outset of synucleinopathic and amyloidogenic disease |
| WO2005001483A2 (en) * | 2003-06-27 | 2005-01-06 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts | Methods for diagnisis and differential diagnosis of dementia disorders |
| US7674599B2 (en) | 2003-11-08 | 2010-03-09 | Elan Pharmaceuticals, Inc. | Methods of using antibodies to detect alpha-synuclein in fluid samples |
| ES2411455T3 (es) * | 2003-11-19 | 2013-07-05 | Rules-Based Medicine, Inc. | Procedimiento para el diagnóstico y la monitorización de la enfermedad de Alzheimer |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| AT500321B1 (de) * | 2003-12-30 | 2006-02-15 | Red Bull Gmbh | Verfahren zur diagnose des down-syndroms |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| US8399241B2 (en) * | 2004-12-01 | 2013-03-19 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| CA2669848A1 (en) * | 2006-11-17 | 2008-05-22 | Friedrich-Alexander-Universitaet Erlangen-Nuernberg | Method of differentially diagnosing dementias |
| JP5558834B2 (ja) * | 2007-02-23 | 2014-07-23 | ヤンセン アルツハイマー イミュノセラピー | シヌクレイノパチーおよびアミロイド形成疾患（ａｍｙｌｏｉｄｏｇｅｎｉｃｄｉｓｅａｓｅ）の予防および処置 |
| EP2020602A1 (de) * | 2007-08-02 | 2009-02-04 | Araclon Biotech | Hochempfindliche Immuntests und Kits zur Bestimmung biologisch interessanter Peptide und Proteine |
| JP2009052933A (ja) * | 2007-08-24 | 2009-03-12 | Rakuno Gakuen | プリオン病の検出方法及び診断キット |
| WO2009039586A2 (en) * | 2007-09-28 | 2009-04-02 | Powmri Limited | Biomarkers for parkinson's disease |
| WO2009086306A1 (en) | 2007-12-21 | 2009-07-09 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| JP5747414B2 (ja) | 2008-04-29 | 2015-07-15 | バイオアークティック ニューロサイエンス アーベー | α−シヌクレイン関連疾患についての治療および診断方法における使用のための抗体およびワクチン |
| WO2009152607A1 (en) * | 2008-06-16 | 2009-12-23 | Ottawa Hospital Research Institute | Methods and kits for diagnosing neurodegenerative disease |
| US20120190652A1 (en) * | 2009-09-16 | 2012-07-26 | United Arab Emirates University | Diagnostic agent for parkinson's disease |
| CA2784919A1 (en) | 2010-01-26 | 2011-07-26 | Banyan Biomarkers, Inc. | Compositions and methods relating to argininosuccinate synthetase |
| NO2539366T3 (de) | 2010-02-26 | 2018-04-07 | ||
| CA2809737A1 (en) * | 2010-04-01 | 2011-10-06 | Banyan Biomarkers, Inc. | Markers and assays for detection of neurotoxicity |
| GB201011420D0 (en) | 2010-07-06 | 2010-08-18 | United Arab Emirates Universit | Method for diagnosis |
| RU2441240C1 (ru) * | 2010-10-05 | 2012-01-27 | Государственное образовательное учреждение высшего профессионального образования "Московский государственный медико-стоматологический университет" Министерства здравоохранения и социального развития Российской Федерации | Способ диагностики аксонально-демиелинизирующих полиневропатий |
| UA118441C2 (uk) * | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| US10942190B2 (en) | 2014-01-21 | 2021-03-09 | Shimadzu Corporation | Measurement method for amyloid precursor protein cleavage peptides |
| CN106574930B (zh) | 2014-05-22 | 2019-09-03 | 株式会社岛津制作所 | 评价脑内的淀粉样蛋白β肽蓄积状态的替代性生物标记物和其分析方法 |
| WO2016038084A1 (en) * | 2014-09-10 | 2016-03-17 | AbbVie Deutschland GmbH & Co. KG | Rgma fragment based diagnostic assay |
| US11268965B2 (en) | 2015-09-16 | 2022-03-08 | Shimadzu Corporation | Multiplex biomarker for use in evaluation of state of accumulation of amyloid B in brain, and analysis method for said evaluation |
| EP3242134A1 (de) * | 2016-05-04 | 2017-11-08 | Euroimmun Medizinische Labordiagnostika AG | Assay zur diagnose einer neurologischen krankheit |
| IL266652B2 (en) * | 2016-11-16 | 2024-11-01 | Nanosomix Inc | Quantification of subpopulations of exosomes and diagnosis of neurodegenerative disorders |
| US10364286B2 (en) * | 2016-12-22 | 2019-07-30 | H. Lundbeck A/S | Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation |
| GB201814807D0 (en) * | 2018-09-12 | 2018-10-24 | Univ Newcastle | Dementia Biomarkers |
| EP3660509B1 (de) * | 2018-11-29 | 2022-03-09 | Hugel Inc. | Zellbasiertes verfahren zur bestimmung der aktivität von botulinumtoxin |
| GB202005732D0 (en) * | 2020-04-20 | 2020-06-03 | Synpromics Ltd | Regulatory nucleic acid sequences |
| MD4172199T2 (ro) | 2020-06-26 | 2025-09-30 | Bioarctic Ab | Anticorpi care leagă protofibrila de alfa-sinucleină |
| US20240003918A1 (en) * | 2020-11-30 | 2024-01-04 | Enigma Biointelligence, Inc. | Non-invasive assessment of alzheimer's disease |
-
1999
- 1999-06-29 WO PCT/EP1999/004483 patent/WO2000002053A2/en not_active Ceased
- 1999-06-29 CA CA002329523A patent/CA2329523A1/en not_active Abandoned
- 1999-06-29 ES ES99934543T patent/ES2255280T3/es not_active Expired - Lifetime
- 1999-06-29 AU AU50290/99A patent/AU754062B2/en not_active Ceased
- 1999-06-29 JP JP2000558397A patent/JP2002519702A/ja active Pending
- 1999-06-29 EP EP99934543A patent/EP1095278B1/de not_active Expired - Lifetime
- 1999-06-29 DE DE69928809T patent/DE69928809T2/de not_active Expired - Lifetime
- 1999-06-29 BR BR9911291-4A patent/BR9911291A/pt not_active IP Right Cessation
- 1999-06-29 CN CN99810286.5A patent/CN1316055A/zh active Pending
- 1999-06-29 DK DK99934543T patent/DK1095278T3/da active
- 1999-06-29 AT AT99934543T patent/ATE312349T1/de active
-
2005
- 2005-11-10 JP JP2005326503A patent/JP2006091025A/ja active Pending
-
2009
- 2009-10-28 JP JP2009247559A patent/JP4580455B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1095278A2 (de) | 2001-05-02 |
| EP1095278B1 (de) | 2005-12-07 |
| JP2002519702A (ja) | 2002-07-02 |
| CN1316055A (zh) | 2001-10-03 |
| DE69928809T2 (de) | 2006-08-31 |
| HK1036834A1 (en) | 2002-01-18 |
| BR9911291A (pt) | 2001-12-04 |
| JP2010019864A (ja) | 2010-01-28 |
| DK1095278T3 (da) | 2006-04-18 |
| DE69928809D1 (de) | 2006-01-12 |
| WO2000002053A3 (en) | 2000-02-24 |
| JP2006091025A (ja) | 2006-04-06 |
| JP4580455B2 (ja) | 2010-11-10 |
| AU754062B2 (en) | 2002-10-31 |
| AU5029099A (en) | 2000-01-24 |
| ES2255280T3 (es) | 2006-06-16 |
| CA2329523A1 (en) | 2000-01-13 |
| WO2000002053A2 (en) | 2000-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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