ATE312349T1 - Differentielle diagnose von neurodegeneration - Google Patents
Differentielle diagnose von neurodegenerationInfo
- Publication number
- ATE312349T1 ATE312349T1 AT99934543T AT99934543T ATE312349T1 AT E312349 T1 ATE312349 T1 AT E312349T1 AT 99934543 T AT99934543 T AT 99934543T AT 99934543 T AT99934543 T AT 99934543T AT E312349 T1 ATE312349 T1 AT E312349T1
- Authority
- AT
- Austria
- Prior art keywords
- neurodegeneration
- differential diagnosis
- methods
- quantification
- relates
- Prior art date
Links
- 230000004770 neurodegeneration Effects 0.000 title abstract 4
- 238000003748 differential diagnosis Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000003556 assay Methods 0.000 abstract 2
- 230000000926 neurological effect Effects 0.000 abstract 2
- 238000011002 quantification Methods 0.000 abstract 2
- 238000011895 specific detection Methods 0.000 abstract 2
- 101150004420 RAB3A gene Proteins 0.000 abstract 1
- 108010057722 Synaptosomal-Associated Protein 25 Proteins 0.000 abstract 1
- 102000004183 Synaptosomal-Associated Protein 25 Human genes 0.000 abstract 1
- 102000003802 alpha-Synuclein Human genes 0.000 abstract 1
- 108090000185 alpha-Synuclein Proteins 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 abstract 1
- 239000013068 control sample Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Eye Examination Apparatus (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98870148 | 1998-07-03 | ||
| EP98870236 | 1998-11-03 | ||
| EP99870069 | 1999-04-09 | ||
| PCT/EP1999/004483 WO2000002053A2 (en) | 1998-07-03 | 1999-06-29 | Differential diagnosis of neurodegeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312349T1 true ATE312349T1 (de) | 2005-12-15 |
Family
ID=27239769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99934543T ATE312349T1 (de) | 1998-07-03 | 1999-06-29 | Differentielle diagnose von neurodegeneration |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1095278B1 (de) |
| JP (3) | JP2002519702A (de) |
| CN (1) | CN1316055A (de) |
| AT (1) | ATE312349T1 (de) |
| AU (1) | AU754062B2 (de) |
| BR (1) | BR9911291A (de) |
| CA (1) | CA2329523A1 (de) |
| DE (1) | DE69928809T2 (de) |
| DK (1) | DK1095278T3 (de) |
| ES (1) | ES2255280T3 (de) |
| WO (1) | WO2000002053A2 (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| WO2002075317A2 (en) * | 2001-03-15 | 2002-09-26 | Novartis Ag | Screening for drugs against disorders associated with schizophrenia |
| AU2002321931A1 (en) * | 2001-11-20 | 2003-06-10 | Atgen Co., Ltd. | Novel peptides conferring environmental stress resistance and fusion proteins including said peptides |
| GB0203446D0 (en) * | 2002-02-14 | 2002-04-03 | Univ Lancaster | Detection and/or monitoring of synuclein-related diseases |
| US9034337B2 (en) | 2003-10-31 | 2015-05-19 | Prothena Biosciences Limited | Treatment and delay of outset of synucleinopathic and amyloidogenic disease |
| WO2005001483A2 (en) * | 2003-06-27 | 2005-01-06 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts | Methods for diagnisis and differential diagnosis of dementia disorders |
| WO2005047860A2 (en) | 2003-11-08 | 2005-05-26 | Elan Pharmaceuticals, Inc. | Antibodies to alpha-synuclein |
| US7598049B2 (en) * | 2003-11-19 | 2009-10-06 | Satoris, Inc. | Methods for diagnosis of Alzheimer's Disease in blood samples |
| US20060094064A1 (en) * | 2003-11-19 | 2006-05-04 | Sandip Ray | Methods and compositions for diagnosis, stratification, and monitoring of alzheimer's disease and other neurological disorders in body fluids |
| DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
| AT500321B1 (de) * | 2003-12-30 | 2006-02-15 | Red Bull Gmbh | Verfahren zur diagnose des down-syndroms |
| DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
| US8399241B2 (en) * | 2004-12-01 | 2013-03-19 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| JP5445844B2 (ja) * | 2006-11-17 | 2014-03-19 | フリードリッヒ−アレクサンダー−ユニバースィタット アーランゲン−ニュールンベルグ | 血管性認知症の鑑別診断のための生体外の方法 |
| PL2583978T3 (pl) * | 2007-02-23 | 2016-07-29 | Prothena Biosciences Ltd Co | Profilaktyka i leczenie chorób synukleinopatycznych i amyloidogennych |
| EP2020602A1 (de) * | 2007-08-02 | 2009-02-04 | Araclon Biotech | Hochempfindliche Immuntests und Kits zur Bestimmung biologisch interessanter Peptide und Proteine |
| JP2009052933A (ja) * | 2007-08-24 | 2009-03-12 | Rakuno Gakuen | プリオン病の検出方法及び診断キット |
| WO2009039586A2 (en) * | 2007-09-28 | 2009-04-02 | Powmri Limited | Biomarkers for parkinson's disease |
| US8501465B2 (en) | 2007-12-21 | 2013-08-06 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| ES2709048T3 (es) | 2008-04-29 | 2019-04-15 | Bioarctic Ab | Anticuerpos y vacunas para su uso en métodos terapéuticos y diagnósticos para trastornos relacionados con alfasinucleína |
| WO2009152607A1 (en) * | 2008-06-16 | 2009-12-23 | Ottawa Hospital Research Institute | Methods and kits for diagnosing neurodegenerative disease |
| CA2774274A1 (en) * | 2009-09-16 | 2011-03-24 | United Arab Emirates University | Diagnostic agent for parkinson's disease |
| JP6063378B2 (ja) | 2010-01-26 | 2017-01-18 | バンヤン・バイオマーカーズ・インコーポレイテッド | アルギニノコハク酸合成酵素に関係する組成物および方法 |
| CN110655573B (zh) | 2010-02-26 | 2023-07-18 | 生命北极神经科学公司 | 原细纤维结合抗体及其治疗和诊断帕金森氏症、路易体痴呆和其他α-共核蛋白病的应用 |
| US20130029362A1 (en) * | 2010-04-01 | 2013-01-31 | Andreas Jeromin | Markers and assays for detection of neurotoxicity |
| GB201011420D0 (en) | 2010-07-06 | 2010-08-18 | United Arab Emirates Universit | Method for diagnosis |
| RU2441240C1 (ru) * | 2010-10-05 | 2012-01-27 | Государственное образовательное учреждение высшего профессионального образования "Московский государственный медико-стоматологический университет" Министерства здравоохранения и социального развития Российской Федерации | Способ диагностики аксонально-демиелинизирующих полиневропатий |
| UA118441C2 (uk) * | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| US10942190B2 (en) | 2014-01-21 | 2021-03-09 | Shimadzu Corporation | Measurement method for amyloid precursor protein cleavage peptides |
| ES2933952T3 (es) | 2014-05-22 | 2023-02-15 | Shimadzu Corp | Biomarcador indirecto para evaluar la acumulación de péptido beta amiloide intracerebral y método para el análisis del mismo |
| WO2016038084A1 (en) * | 2014-09-10 | 2016-03-17 | AbbVie Deutschland GmbH & Co. KG | Rgma fragment based diagnostic assay |
| EP4424704A3 (de) | 2015-09-16 | 2024-12-25 | Shimadzu Corporation | Multiplex-biomarker zur verwendung bei der beurteilung des akkumulationszustands von amyloid b im gehirn und analyseverfahren für besagte beurteilung |
| EP3242134A1 (de) * | 2016-05-04 | 2017-11-08 | Euroimmun Medizinische Labordiagnostika AG | Assay zur diagnose einer neurologischen krankheit |
| IL266652B2 (en) * | 2016-11-16 | 2024-11-01 | Nanosomix Inc | Quantification of subpopulations of exosomes and diagnosis of neurodegenerative disorders |
| US10364286B2 (en) * | 2016-12-22 | 2019-07-30 | H. Lundbeck A/S | Monoclonal anti-alpha-synuclein antibodies for preventing tau aggregation |
| GB201814807D0 (en) * | 2018-09-12 | 2018-10-24 | Univ Newcastle | Dementia Biomarkers |
| LT3660509T (lt) * | 2018-11-29 | 2022-05-10 | Hugel Inc. | Ląstelių panaudojimu paremtas būdas botulino toksino aktyvumui nustatyti |
| GB202005732D0 (en) * | 2020-04-20 | 2020-06-03 | Synpromics Ltd | Regulatory nucleic acid sequences |
| HRP20250812T1 (hr) | 2020-06-26 | 2025-09-12 | Bioarctic Ab | Antitijela koja vežu alfa-sinuklein protofibril |
| WO2022115705A2 (en) * | 2020-11-30 | 2022-06-02 | Enigma Biointelligence, Inc. | Non-invasive assessment of alzheimer's disease |
-
1999
- 1999-06-29 WO PCT/EP1999/004483 patent/WO2000002053A2/en not_active Ceased
- 1999-06-29 JP JP2000558397A patent/JP2002519702A/ja active Pending
- 1999-06-29 DK DK99934543T patent/DK1095278T3/da active
- 1999-06-29 CN CN99810286.5A patent/CN1316055A/zh active Pending
- 1999-06-29 BR BR9911291-4A patent/BR9911291A/pt not_active IP Right Cessation
- 1999-06-29 CA CA002329523A patent/CA2329523A1/en not_active Abandoned
- 1999-06-29 ES ES99934543T patent/ES2255280T3/es not_active Expired - Lifetime
- 1999-06-29 DE DE69928809T patent/DE69928809T2/de not_active Expired - Lifetime
- 1999-06-29 AU AU50290/99A patent/AU754062B2/en not_active Ceased
- 1999-06-29 AT AT99934543T patent/ATE312349T1/de active
- 1999-06-29 EP EP99934543A patent/EP1095278B1/de not_active Expired - Lifetime
-
2005
- 2005-11-10 JP JP2005326503A patent/JP2006091025A/ja active Pending
-
2009
- 2009-10-28 JP JP2009247559A patent/JP4580455B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1316055A (zh) | 2001-10-03 |
| ES2255280T3 (es) | 2006-06-16 |
| HK1036834A1 (en) | 2002-01-18 |
| WO2000002053A2 (en) | 2000-01-13 |
| JP4580455B2 (ja) | 2010-11-10 |
| BR9911291A (pt) | 2001-12-04 |
| EP1095278B1 (de) | 2005-12-07 |
| DE69928809D1 (de) | 2006-01-12 |
| DK1095278T3 (da) | 2006-04-18 |
| JP2010019864A (ja) | 2010-01-28 |
| WO2000002053A3 (en) | 2000-02-24 |
| EP1095278A2 (de) | 2001-05-02 |
| AU5029099A (en) | 2000-01-24 |
| JP2002519702A (ja) | 2002-07-02 |
| DE69928809T2 (de) | 2006-08-31 |
| CA2329523A1 (en) | 2000-01-13 |
| AU754062B2 (en) | 2002-10-31 |
| JP2006091025A (ja) | 2006-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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