ATE312936T1 - Methode und katalytisches system zur stereoselektiven invertierung eines chiralen zentrums in einer chemischen verbindung - Google Patents

Methode und katalytisches system zur stereoselektiven invertierung eines chiralen zentrums in einer chemischen verbindung

Info

Publication number
ATE312936T1
ATE312936T1 AT01920132T AT01920132T ATE312936T1 AT E312936 T1 ATE312936 T1 AT E312936T1 AT 01920132 T AT01920132 T AT 01920132T AT 01920132 T AT01920132 T AT 01920132T AT E312936 T1 ATE312936 T1 AT E312936T1
Authority
AT
Austria
Prior art keywords
chiral center
chemical compound
catalytic system
stereoselectively
stereoselective
Prior art date
Application number
AT01920132T
Other languages
English (en)
Inventor
Weiguo Liu
Scott Laneman
David John Ager
Paul Phillip Taylor
Original Assignee
Excelsyn Molecular Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Excelsyn Molecular Dev Ltd filed Critical Excelsyn Molecular Dev Ltd
Application granted granted Critical
Publication of ATE312936T1 publication Critical patent/ATE312936T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT01920132T 2000-02-23 2001-02-22 Methode und katalytisches system zur stereoselektiven invertierung eines chiralen zentrums in einer chemischen verbindung ATE312936T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51088200A 2000-02-23 2000-02-23
PCT/US2001/005688 WO2001062948A2 (en) 2000-02-23 2001-02-22 Method and catalyst system for stereoselectively inverting a chiral center of a chemical compound

Publications (1)

Publication Number Publication Date
ATE312936T1 true ATE312936T1 (de) 2005-12-15

Family

ID=24032576

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01920132T ATE312936T1 (de) 2000-02-23 2001-02-22 Methode und katalytisches system zur stereoselektiven invertierung eines chiralen zentrums in einer chemischen verbindung

Country Status (7)

Country Link
US (1) US6365380B2 (de)
EP (1) EP1257659B1 (de)
JP (1) JP2003523750A (de)
AT (1) ATE312936T1 (de)
AU (1) AU2001247218A1 (de)
DE (1) DE60115849T2 (de)
WO (1) WO2001062948A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SV2003000617A (es) * 2000-08-31 2003-01-13 Lilly Co Eli Inhibidores de la proteasa peptidomimetica ref. x-14912m
US7202070B2 (en) * 2000-10-31 2007-04-10 Biocatalytics, Inc. Method for reductive amination of a ketone using a mutated enzyme
GB0206415D0 (en) * 2002-03-19 2002-05-01 Glaxo Group Ltd Deracemisation of amines
WO2006113085A2 (en) * 2005-03-28 2006-10-26 Biocatalytics, Inc. D-amino acid dehydrogenase and method of making d-amino acids
US8133717B2 (en) 2006-12-22 2012-03-13 Richmond Chemical Corporation Stereoinversion of amino acids in a single reactor
EP2132322A4 (de) * 2007-03-02 2013-02-20 Richmond Chemical Corp Verfahren zur erhöhung der ausbeute und verbesserung der reinigung von produkten aus transaminasereaktionen
PL2225271T3 (pl) * 2007-12-03 2013-12-31 Italfarmaco Spa Nowe nieselektywne analogi somatostatyny
EP2067786A1 (de) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Neue nichtselektive Analoga von Somatostatin
CN110938580A (zh) * 2019-12-26 2020-03-31 江南大学 一种提高d-酪氨酸生产效率的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1767389A1 (de) 1968-05-06 1971-09-02 Bayer Ag Verfahren zur Abtrennung von Pyrogenen aus Rohpraeparaten von L-Asparaginase
CH586233A5 (de) 1971-01-18 1977-03-31 Pentapharm Ag
HU193902B (en) 1983-09-01 1987-12-28 Genetics Inst Process for preparing l-amino acids by means of transamination
GB8700462D0 (en) 1987-01-09 1987-02-11 Shell Int Research Alkene derivatives
US5135860A (en) 1991-11-06 1992-08-04 E. I. Du Pont De Nemours And Company Process for preparing glyoxylic acid/aminomethylphosphonic acid mixtures
US5364797A (en) 1993-05-20 1994-11-15 Mobil Oil Corp. Sensor device containing mesoporous crystalline material
GB9410388D0 (en) 1994-05-24 1994-07-13 Erba Carlo Spa Method for the preparation of 9-amino camptothecin
JPH08322591A (ja) * 1995-06-02 1996-12-10 Sumitomo Pharmaceut Co Ltd 光学分割により光学的に純粋な１，２，３，４−テトラヒドロキノリン−２−酢酸エステル類を得る方法
US5728555A (en) 1996-09-30 1998-03-17 Monsanto Company Preparation of d-amino acids by direct fermentative means
US5922183A (en) 1997-06-23 1999-07-13 Eic Laboratories, Inc. Metal oxide matrix biosensors

Also Published As

Publication number Publication date
US20010021519A1 (en) 2001-09-13
US6365380B2 (en) 2002-04-02
AU2001247218A1 (en) 2001-09-03
EP1257659A2 (de) 2002-11-20
DE60115849T2 (de) 2006-08-03
EP1257659B1 (de) 2005-12-14
WO2001062948A3 (en) 2002-03-07
DE60115849D1 (de) 2006-01-19
JP2003523750A (ja) 2003-08-12
WO2001062948A2 (en) 2001-08-30

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