ATE314345T1 - N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung - Google Patents

N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung

Info

Publication number
ATE314345T1
ATE314345T1 AT00941870T AT00941870T ATE314345T1 AT E314345 T1 ATE314345 T1 AT E314345T1 AT 00941870 T AT00941870 T AT 00941870T AT 00941870 T AT00941870 T AT 00941870T AT E314345 T1 ATE314345 T1 AT E314345T1
Authority
AT
Austria
Prior art keywords
aromatic
bis
phenyl
disubstituted
hydroxy
Prior art date
Application number
AT00941870T
Other languages
English (en)
Inventor
Donglu Bai
Weizhou Chen
Yunxin Bu
Yiping Wang
Yueli Dong
Aili Kang
Original Assignee
Shanghai Inst Materia Medica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica filed Critical Shanghai Inst Materia Medica
Application granted granted Critical
Publication of ATE314345T1 publication Critical patent/ATE314345T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00941870T 1999-12-10 2000-07-03 N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung ATE314345T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB99124236XA CN1172908C (zh) 1999-12-10 1999-12-10 N-取代苄基或苯基芳香磺酰胺化合物及其用途
PCT/CN2000/000187 WO2001042204A1 (en) 1999-12-10 2000-07-03 N-substituted benzyl or phenyl aromatic sulfamides compounds and the use thereof

Publications (1)

Publication Number Publication Date
ATE314345T1 true ATE314345T1 (de) 2006-01-15

Family

ID=5283321

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00941870T ATE314345T1 (de) 1999-12-10 2000-07-03 N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung

Country Status (7)

Country Link
US (1) US6605635B1 (de)
EP (1) EP1245561B1 (de)
JP (1) JP4015853B2 (de)
CN (1) CN1172908C (de)
AT (1) ATE314345T1 (de)
DE (1) DE60025270T2 (de)
WO (1) WO2001042204A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220736C (zh) * 2000-12-15 2005-09-28 舒飞士特种化工有限公司 辐射固化油墨印刷和涂布技术中颜料和/或染料的表面官能化作用
EP2501381B1 (de) * 2009-11-17 2017-07-26 Huya Bioscience International LLC Behandlung von vorhofflimmern
EP2501380B1 (de) * 2009-11-17 2016-01-27 Huya Bioscience International LLC Langsame infusion von sulcardin und seinen salzen
CN113453677A (zh) 2018-12-13 2021-09-28 沪亚生物国际有限责任公司 用于治疗急性心房颤动的舒卡定施用
SG11202108160YA (en) * 2019-01-29 2021-08-30 Huya Bioscience International Llc Sulcardine salts
EP3968979A4 (de) 2019-05-15 2023-03-01 Bexson Biomedical, Inc. Ketaminformulierung für subkutane injektion
IL298907A (en) * 2020-06-12 2023-02-01 Huyabio Int Llc Administering sulcardin for the treatment of acute atrial fibrillation
JP2023551145A (ja) 2020-11-18 2023-12-07 ベクソン バイオメディカル，インク． 医薬化合物の錯化剤塩製剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059620A (en) 1985-12-27 1991-10-22 The Du Pont Merck Pharmaceutical Company Aryl substituted aminomethyl benzene derivatives

Also Published As

Publication number Publication date
CN1299813A (zh) 2001-06-20
EP1245561B1 (de) 2005-12-28
DE60025270T2 (de) 2006-08-17
JP4015853B2 (ja) 2007-11-28
EP1245561A1 (de) 2002-10-02
US6605635B1 (en) 2003-08-12
DE60025270D1 (de) 2006-02-02
JP2003516385A (ja) 2003-05-13
WO2001042204A1 (en) 2001-06-14
CN1172908C (zh) 2004-10-27
EP1245561A4 (de) 2003-04-23

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Legal Events

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