ATE314345T1 - N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung - Google Patents

N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung

Info

Publication number
ATE314345T1
ATE314345T1 AT00941870T AT00941870T ATE314345T1 AT E314345 T1 ATE314345 T1 AT E314345T1 AT 00941870 T AT00941870 T AT 00941870T AT 00941870 T AT00941870 T AT 00941870T AT E314345 T1 ATE314345 T1 AT E314345T1
Authority
AT
Austria
Prior art keywords
aromatic
bis
phenyl
disubstituted
hydroxy
Prior art date
Application number
AT00941870T
Other languages
English (en)
Inventor
Donglu Bai
Weizhou Chen
Yunxin Bu
Yiping Wang
Yueli Dong
Aili Kang
Original Assignee
Shanghai Inst Materia Medica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica filed Critical Shanghai Inst Materia Medica
Application granted granted Critical
Publication of ATE314345T1 publication Critical patent/ATE314345T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00941870T 1999-12-10 2000-07-03 N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung ATE314345T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB99124236XA CN1172908C (zh) 1999-12-10 1999-12-10 N-取代苄基或苯基芳香磺酰胺化合物及其用途
PCT/CN2000/000187 WO2001042204A1 (en) 1999-12-10 2000-07-03 N-substituted benzyl or phenyl aromatic sulfamides compounds and the use thereof

Publications (1)

Publication Number Publication Date
ATE314345T1 true ATE314345T1 (de) 2006-01-15

Family

ID=5283321

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00941870T ATE314345T1 (de) 1999-12-10 2000-07-03 N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung

Country Status (7)

Country Link
US (1) US6605635B1 (de)
EP (1) EP1245561B1 (de)
JP (1) JP4015853B2 (de)
CN (1) CN1172908C (de)
AT (1) ATE314345T1 (de)
DE (1) DE60025270T2 (de)
WO (1) WO2001042204A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030064824A (ko) * 2000-12-15 2003-08-02 유씨비 소시에떼아노님 조사 경화성 잉크 프린팅 및 코팅 적용을 위한 안료및/또는 염료의 표면 작용성화 방법
PL3311810T3 (pl) * 2009-11-17 2022-12-05 Huyabio International, Llc Zastosowanie sulkardyny do leczenia migotania przedsionków
CN102869357A (zh) * 2009-11-17 2013-01-09 沪亚生物国际有限责任公司 舒欣啶及其盐的缓慢滴注
US11364223B2 (en) 2018-12-13 2022-06-21 Huyabio International, Llc Sulcardine administration for treatment of acute atrial fibrillation
AU2020216925B2 (en) 2019-01-29 2022-09-15 Huyabio International, Llc Sulcardine salts
WO2020232274A1 (en) 2019-05-15 2020-11-19 Bexson Biomedical, Inc. Ketamine formulation for subcutaneous injection
CA3182015A1 (en) * 2020-06-12 2021-12-16 Gary Elliott Sulcardine administration for treatment of acute atrial fibrillation
EP4247340A4 (de) 2020-11-18 2024-10-02 Bexson Biomedical, Inc. Komplexbildnersalzformulierungen von pharmazeutischen verbindungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059620A (en) 1985-12-27 1991-10-22 The Du Pont Merck Pharmaceutical Company Aryl substituted aminomethyl benzene derivatives

Also Published As

Publication number Publication date
DE60025270T2 (de) 2006-08-17
JP2003516385A (ja) 2003-05-13
EP1245561B1 (de) 2005-12-28
CN1172908C (zh) 2004-10-27
JP4015853B2 (ja) 2007-11-28
DE60025270D1 (de) 2006-02-02
WO2001042204A1 (en) 2001-06-14
EP1245561A4 (de) 2003-04-23
CN1299813A (zh) 2001-06-20
EP1245561A1 (de) 2002-10-02
US6605635B1 (en) 2003-08-12

Similar Documents

Publication Publication Date Title
ATE428421T1 (de) Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften
ATE248837T1 (de) Chinuclidin-acrylamide
EP1201239A4 (de) Cyclische amine als ccr3 antagonisten
MA28010A1 (fr) Derives de piperazine et leur utilisation comme agents therapeutiques
BR0307351A (pt) Composto, composição farmacêutica, método para tratar uma condição ou estado de doença mediados pela atividade de p38 quinase ou mediados por citocinas produzidas pela atividade de p38 quinase, uso de um composto, e, processo para preparar um composto
NO20082136L (no) 1,5-substituerte indol-2-yl-amidderivater
ATE537141T1 (de) Bicycloesterderivat
DE60045508D1 (de) Dalda-analoge und ihre verwendung
DE3852085D1 (de) Substituierte N-(1-Alkyl-3-hydroxy-4-piperidinyl)benzamide.
DE69803048D1 (de) Aminosulfonylharnstoffe mit herbizider wirkung
DE60025270D1 (de) N-substituierte benzyl oder phenyl arylsulfamide und ihre verwendung
WO2004041802A8 (en) 4(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain or gastrointestinal disorders
NO20052699L (no) 4(fenylpiperazinyl-metyl)benzamid-derivater og deres anvendelse ved behandling av smerte og gastrointestinale lidelser.
NO20023001L (no) Substituerte piperazinderivater som MTP inhibitorer
ATE327980T1 (de) 3-heterocyclyl-substituierte benzoesäurederivate
ES2124861T3 (es) Derivados de aminoacidos y su utilizacion como inhibidores de la encefalinasa.
PT1254905E (pt) 4-(2-piridil) piperizinas possuindo actividade agonista do receptor 5ht7
DK0916670T3 (da) Pyrrolo[3,2-b]pyridiner og deres anvendelse som 5-HT1f-agonister
ES2101373T3 (es) Tetrahidrociclopent(b)indol-metaminas y compuestos relacionados, un procedimiento para su preparacion y su uso como medicamentos.
DE60123528D1 (de) Verwendung eines Mittels zur Verbesserung der Astrozytenfunktion zur Behandlung von Parkinsons Krankheit
ATE440835T1 (de) Heterozyklische harnstoff-derivate für die behandlung von schmerzen.
DK1104419T3 (da) N-substituerede azabicyloheptan-derivater, deres fremstilling og anvendelse
EP1325918A4 (de) Herzmuskelzellen-apoptose hemmstoffe und behandlung/vorbeugung von herzkrankheiten
ATE457305T1 (de) Neue 3-phenylpropionsäurederivate zur behandlung von diabetes
ATE283269T1 (de) 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties