ATE314864T1 - Verfahren zur schützung gegen ionisierende strahlung oder chemotherapeutisches-arzneimittel- schaden durch in vivo gentherapie - Google Patents

Verfahren zur schützung gegen ionisierende strahlung oder chemotherapeutisches-arzneimittel- schaden durch in vivo gentherapie

Info

Publication number
ATE314864T1
ATE314864T1 AT99921357T AT99921357T ATE314864T1 AT E314864 T1 ATE314864 T1 AT E314864T1 AT 99921357 T AT99921357 T AT 99921357T AT 99921357 T AT99921357 T AT 99921357T AT E314864 T1 ATE314864 T1 AT E314864T1
Authority
AT
Austria
Prior art keywords
subject
ionizing radiation
gene therapy
protection against
vivo gene
Prior art date
Application number
AT99921357T
Other languages
English (en)
Inventor
Joel S Greenberger
Original Assignee
Univ Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh filed Critical Univ Pittsburgh
Application granted granted Critical
Publication of ATE314864T1 publication Critical patent/ATE314864T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99921357T 1998-05-11 1999-05-07 Verfahren zur schützung gegen ionisierende strahlung oder chemotherapeutisches-arzneimittel- schaden durch in vivo gentherapie ATE314864T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/075,532 US6221848B1 (en) 1998-05-11 1998-05-11 Protection of the esophagus from chemotherapeutic or irradiation damage by gene therapy

Publications (1)

Publication Number Publication Date
ATE314864T1 true ATE314864T1 (de) 2006-02-15

Family

ID=22126381

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99921357T ATE314864T1 (de) 1998-05-11 1999-05-07 Verfahren zur schützung gegen ionisierende strahlung oder chemotherapeutisches-arzneimittel- schaden durch in vivo gentherapie

Country Status (10)

Country Link
US (1) US6221848B1 (de)
EP (1) EP1077728B1 (de)
JP (1) JP2002514608A (de)
AT (1) ATE314864T1 (de)
AU (1) AU769805B2 (de)
CA (1) CA2331569A1 (de)
DE (1) DE69929327T2 (de)
ES (1) ES2257049T3 (de)
PT (1) PT1077728E (de)
WO (1) WO1999058154A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887856B1 (en) * 1993-10-15 2005-05-03 University Of Pittsburgh Protection from ionizing irradiation or chemotherapeutic drug damage by in vivo gene therapy
EP2300607A2 (de) * 2008-06-26 2011-03-30 Spectrum Health Innovations, LLC Verfahren zur behandlung und verhinderung von strahlungsschäden mithilfe genetisch modifizierter mesenchymaler stammzellen
WO2009158563A1 (en) * 2008-06-26 2009-12-30 Spectrum Health Method for treating or preventing radiation damage by in vivo gene therapy
US20140199368A1 (en) * 2010-11-15 2014-07-17 University of Pittsburg-Of the Commonwealth System of Higher Education-Office of Technolology Manage Intraesophageal administration of targeted nitroxide agents for protection against ionizing irradiation-induced esophagitis
WO2022244757A1 (ja) * 2021-05-18 2022-11-24 株式会社Ｌｔｔバイオファーマ 抗癌剤の投与に伴う障害を治療又は予防するための医薬組成物
WO2023224135A1 (ko) * 2022-05-16 2023-11-23 주식회사 제노포커스 수퍼옥시드 디스뮤타제 및 이의 점막염 예방 또는 치료용 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980286A (en) 1985-07-05 1990-12-25 Whitehead Institute For Biomedical Research In vivo introduction and expression of foreign genetic material in epithelial cells
DE3854872D1 (de) 1987-03-14 1996-02-22 Boehringer Ingelheim Int Humane Mangan-Superoxiddismutase (hMn-SOD)
US5858784A (en) 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
US5843641A (en) * 1993-02-26 1998-12-01 Massachusetts Institute Of Technology Methods for the daignosis, of familial amyotrophic lateral sclerosis
WO1994021283A1 (en) 1993-03-24 1994-09-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for inhibiting pulmonary oxygen toxicity using manganese superoxide dismutase
US5599712A (en) * 1993-10-15 1997-02-04 University Of Pittsburgh Protection from ionizing irradiation or chemotherapeutic drug damage by in vivo gene therapy
US5985261A (en) * 1996-06-28 1999-11-16 National Jewish Medical And Research Center Use of thioredoxin-like molecules for induction of MnSOD to treat oxidative damage

Also Published As

Publication number Publication date
WO1999058154A1 (en) 1999-11-18
AU769805B2 (en) 2004-02-05
EP1077728A1 (de) 2001-02-28
CA2331569A1 (en) 1999-11-18
PT1077728E (pt) 2006-05-31
AU3859399A (en) 1999-11-29
US6221848B1 (en) 2001-04-24
ES2257049T3 (es) 2006-07-16
DE69929327D1 (de) 2006-03-30
EP1077728B1 (de) 2006-01-04
DE69929327T2 (de) 2006-09-07
JP2002514608A (ja) 2002-05-21

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Legal Events

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