ATE315335T1 - Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung - Google Patents
Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendungInfo
- Publication number
- ATE315335T1 ATE315335T1 AT01989340T AT01989340T ATE315335T1 AT E315335 T1 ATE315335 T1 AT E315335T1 AT 01989340 T AT01989340 T AT 01989340T AT 01989340 T AT01989340 T AT 01989340T AT E315335 T1 ATE315335 T1 AT E315335T1
- Authority
- AT
- Austria
- Prior art keywords
- indolocarbazole
- anticancer agents
- relates
- compositions
- activity
- Prior art date
Links
- VVVPGLRKXQSQSZ-UHFFFAOYSA-N indolo[3,2-c]carbazole Chemical compound C1=CC=CC2=NC3=C4C5=CC=CC=C5N=C4C=CC3=C21 VVVPGLRKXQSQSZ-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229960005544 indolocarbazole Drugs 0.000 title 1
- 102000003915 DNA Topoisomerases Human genes 0.000 abstract 1
- 108090000323 DNA Topoisomerases Proteins 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/044—Pyrrole radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24446900P | 2000-10-31 | 2000-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE315335T1 true ATE315335T1 (de) | 2006-02-15 |
Family
ID=22922901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01989340T ATE315335T1 (de) | 2000-10-31 | 2001-10-29 | Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6605596B2 (de) |
| EP (1) | EP1341412B1 (de) |
| JP (1) | JP4060709B2 (de) |
| AT (1) | ATE315335T1 (de) |
| AU (2) | AU4344202A (de) |
| CA (1) | CA2426754C (de) |
| DE (1) | DE60116664T2 (de) |
| WO (1) | WO2002048166A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001062769A1 (fr) | 2000-02-24 | 2001-08-30 | Banyu Pharmaceutical Co., Ltd. | Procede de preparation de derives d'indolopyrrolocarbazole, leurs intermediaires, et procede de preparation des intermediaires |
| US7122526B2 (en) * | 2000-10-31 | 2006-10-17 | Nanosphere, Inc. | Indolocarbazole anticancer agents and methods of using same |
| KR101413988B1 (ko) * | 2012-04-25 | 2014-07-01 | (주)이스트소프트 | 문서의 이산분리시스템 및 방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5364858A (en) | 1987-03-31 | 1994-11-15 | Research Triangle Institute | Camptothecin analogs as potent inhibitors of topoisomerase I |
| US5106742A (en) | 1987-03-31 | 1992-04-21 | Wall Monroe E | Camptothecin analogs as potent inhibitors of topoisomerase I |
| US5559235A (en) | 1991-10-29 | 1996-09-24 | Glaxo Wellcome Inc. | Water soluble camptothecin derivatives |
| US5437996A (en) | 1992-11-24 | 1995-08-01 | Banyu Pharmaceutical Co., Ltd. | Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives |
| US5589365A (en) | 1991-11-29 | 1996-12-31 | Banyu Pharmaceutical Co., Ltd. | Process for producing glycosylated indolopyrrolocarbazole derivatives by culturing certain microorganisms |
| US5591842A (en) * | 1991-11-29 | 1997-01-07 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
| US5668271A (en) | 1991-11-29 | 1997-09-16 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
| DE4217964A1 (de) | 1992-05-30 | 1993-12-02 | Goedecke Ag | Indolocarbazol-Imide und deren Verwendung |
| US5804564A (en) | 1994-05-09 | 1998-09-08 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
| US5922860A (en) | 1994-05-09 | 1999-07-13 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
| AU3086495A (en) | 1994-08-02 | 1996-03-04 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazoles |
| AU6836696A (en) | 1995-09-05 | 1997-03-27 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
| US5859261A (en) | 1997-03-20 | 1999-01-12 | Eli Lilly And Company | Synthesis of indolylmaleimides |
-
2001
- 2001-10-29 AT AT01989340T patent/ATE315335T1/de not_active IP Right Cessation
- 2001-10-29 AU AU4344202A patent/AU4344202A/xx active Pending
- 2001-10-29 JP JP2002549697A patent/JP4060709B2/ja not_active Expired - Fee Related
- 2001-10-29 WO PCT/US2001/051338 patent/WO2002048166A1/en not_active Ceased
- 2001-10-29 EP EP01989340A patent/EP1341412B1/de not_active Expired - Lifetime
- 2001-10-29 CA CA002426754A patent/CA2426754C/en not_active Expired - Fee Related
- 2001-10-29 AU AU2002243442A patent/AU2002243442B2/en not_active Ceased
- 2001-10-29 US US10/057,260 patent/US6605596B2/en not_active Expired - Fee Related
- 2001-10-29 DE DE60116664T patent/DE60116664T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1341412A1 (de) | 2003-09-10 |
| WO2002048166A1 (en) | 2002-06-20 |
| CA2426754C (en) | 2008-03-25 |
| US20030087842A1 (en) | 2003-05-08 |
| AU2002243442B2 (en) | 2004-11-04 |
| AU4344202A (en) | 2002-06-24 |
| EP1341412B1 (de) | 2006-01-11 |
| JP4060709B2 (ja) | 2008-03-12 |
| CA2426754A1 (en) | 2002-06-20 |
| WO2002048166A8 (en) | 2003-01-03 |
| JP2004515554A (ja) | 2004-05-27 |
| DE60116664D1 (de) | 2006-04-06 |
| US6605596B2 (en) | 2003-08-12 |
| DE60116664T2 (de) | 2006-09-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TR200102029T2 (tr) | 1-Heterosiklil ikameli diarilaminler. | |
| UY26205A1 (es) | Derivados de indoloxoacetil piperazina antiviricos | |
| PT1140944E (pt) | Derivados de epotilona e sua utilizacao como agentes antitumorais | |
| DE69824029D1 (de) | Bicyclische kinase inhibitoren | |
| ATE450251T1 (de) | Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung | |
| DE69925276D1 (de) | Stoffe und zusammensetzungen für die verabreichung aktiver substanzen | |
| ID27535A (id) | Turunan pirasola sebagai inhibitor p-38 map kinase | |
| AU3652102A (en) | Compounds and their uses | |
| DE60029799D1 (de) | Verbindungen, verfahren und pharmazeutische zubereitungen zur behandlung von zellschäden wie zum beispiel schäden an nerven- oder kerzgefässgewebe | |
| EP1071474A4 (de) | Substituierte porphyrine | |
| AU2003228770A8 (en) | Substituted pyrazolopyrimidines | |
| TW200510407A (en) | Novel pyrrolodihydroisoquinolines as PDE 10 inhibitors | |
| PT998460E (pt) | Novos derivados de tetrazole | |
| ATE426628T1 (de) | Polyurethanderivatzusammensetzungen und verfahren zu ihrer herstellung | |
| TW200514772A (en) | Novel tetrahydropyridine derivatives | |
| DE60021381D1 (de) | Chinonverbindungen zur behandlung von krankheiten | |
| DE60013098D1 (de) | Zusammensetzung zur hautdesinfizierung | |
| DK1276491T3 (da) | Tamandarin- og didemnin-analoger og fremgangsmåder til fremstilling og anvendelse af dem | |
| ATE383345T1 (de) | Quinoxalin-3-on-verdindungen als orexin-rezeptor antagonisten. | |
| ATE202483T1 (de) | Immuntolerante prothrombinkomplex-präparation | |
| TNSN05133A1 (en) | Imidazoquinoline derivatives as adenosine a3 receptor ligands | |
| BR0318521A (pt) | arilindenopiridinas e arilindenopirimidinas e métodos terapêuticos e profiláticos relacionados | |
| AR028947A1 (es) | Compuestos novedosos | |
| WO2002024867A3 (en) | Novel compositions and methods for lymphoma and leukemia | |
| DE60116664D1 (de) | Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |