ATE317268T1 - Verwendung eines h1-antagonisten und von rimexolon als sicheres steroid zur behandlung von rhinitis - Google Patents
Verwendung eines h1-antagonisten und von rimexolon als sicheres steroid zur behandlung von rhinitisInfo
- Publication number
- ATE317268T1 ATE317268T1 AT02804694T AT02804694T ATE317268T1 AT E317268 T1 ATE317268 T1 AT E317268T1 AT 02804694 T AT02804694 T AT 02804694T AT 02804694 T AT02804694 T AT 02804694T AT E317268 T1 ATE317268 T1 AT E317268T1
- Authority
- AT
- Austria
- Prior art keywords
- rimexolone
- antagonist
- treat rhinitis
- safe steroid
- safe
- Prior art date
Links
- 206010039083 rhinitis Diseases 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 title abstract 2
- 239000000938 histamine H1 antagonist Substances 0.000 title 1
- QTTRZHGPGKRAFB-OOKHYKNYSA-N rimexolone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CC)(C)[C@@]1(C)C[C@@H]2O QTTRZHGPGKRAFB-OOKHYKNYSA-N 0.000 title 1
- 229960001487 rimexolone Drugs 0.000 title 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 239000000043 antiallergic agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33737101P | 2001-12-05 | 2001-12-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE317268T1 true ATE317268T1 (de) | 2006-02-15 |
Family
ID=23320292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02804694T ATE317268T1 (de) | 2001-12-05 | 2002-11-18 | Verwendung eines h1-antagonisten und von rimexolon als sicheres steroid zur behandlung von rhinitis |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20040242638A1 (de) |
| EP (1) | EP1467762B1 (de) |
| JP (1) | JP2005511724A (de) |
| KR (1) | KR20050044550A (de) |
| CN (1) | CN1599625A (de) |
| AT (1) | ATE317268T1 (de) |
| AU (1) | AU2002366567B2 (de) |
| BR (1) | BR0214643A (de) |
| CA (1) | CA2468749A1 (de) |
| CY (1) | CY1105607T1 (de) |
| DE (1) | DE60209154T2 (de) |
| DK (1) | DK1467762T3 (de) |
| ES (1) | ES2258175T3 (de) |
| MX (1) | MXPA04005417A (de) |
| PL (1) | PL369630A1 (de) |
| WO (1) | WO2003049770A1 (de) |
| ZA (1) | ZA200403813B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2389530B (en) * | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| CA2495830C (en) | 2002-08-30 | 2012-08-21 | Altana Pharma Ag | The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis |
| CA2504200A1 (en) * | 2002-11-12 | 2004-05-27 | Alcon, Inc. | The use of an anti-allergy agent and a steroid to treat allergic rhinitis |
| US20050255154A1 (en) | 2004-05-11 | 2005-11-17 | Lena Pereswetoff-Morath | Method and composition for treating rhinitis |
| US20070020330A1 (en) | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
| PL2486942T3 (pl) | 2004-11-24 | 2019-05-31 | Meda Pharmaceuticals Inc | Kompozycje zawierające azelastynę oraz sposoby ich stosowania |
| US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
| WO2006097458A1 (en) * | 2005-03-15 | 2006-09-21 | Nycomed Gmbh | Novel combination |
| PT1919450E (pt) * | 2005-09-01 | 2014-09-10 | Meda Ab | Composição lipossomal contendo anti-histamínico e corticosteróide e sua utilização para a preparação de um medicamento para o tratamento de rinite e distúrbios relacionados |
| WO2008098122A2 (en) * | 2007-02-08 | 2008-08-14 | Inspire Pharmaceuticals, Inc. | Method for treating allergic rhinitis without adverse effects |
| US20100008868A1 (en) * | 2007-11-27 | 2010-01-14 | Harry Dugger | Sustained remission of atopic dermatitis |
| PT3943069T (pt) | 2009-03-17 | 2025-02-21 | Nicox Ophthalmics Inc | Formulações oftálmicas de cetirizina e métodos de utilização |
| US8569273B2 (en) | 2009-03-17 | 2013-10-29 | Aciex Therapeutics, Inc. | Ophthalmic formulations of cetirizine and methods of use |
| JP5683719B2 (ja) | 2011-01-04 | 2015-03-11 | イスタ・ファーマシューティカルズ・インコーポレイテッドＩｓｔａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | ベポタスチン組成物 |
| AU2021291684A1 (en) * | 2020-06-15 | 2022-12-08 | Alkem Laboratories Limited | Combination of alcaftadine and a corticosteroid |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5879983A (ja) * | 1981-11-06 | 1983-05-13 | Kanebo Ltd | 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物 |
| US5223493A (en) * | 1984-12-28 | 1993-06-29 | Alcon Laboratories, Inc. | Anti-inflammatory compounds for ophthalmic use |
| GB8520662D0 (en) * | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4923892A (en) * | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| US5149694A (en) * | 1988-03-09 | 1992-09-22 | Alcon Laboratories, Inc. | Combination of tobramycin and dexamethasone for topical ophthalmic use |
| US5192780A (en) * | 1989-12-18 | 1993-03-09 | Alcon Laboratories, Inc. | Methods using antiallergics and antihistamines |
| JP3527256B2 (ja) * | 1992-12-09 | 2004-05-17 | ロート製薬株式会社 | 抗アレルギー点眼剤 |
| US5668133A (en) * | 1992-12-09 | 1997-09-16 | Alcon Laboratories, Inc. | Ophthalmic compositions comprising emedastine and methods for their use |
| US5420120A (en) * | 1993-12-17 | 1995-05-30 | Alcon Laboratories, Inc. | Anti-inflammatory glucocorticoid compounds for topical ophthalmic use |
| US5595997A (en) * | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
| US5641805A (en) * | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| WO1997001337A1 (en) * | 1995-06-29 | 1997-01-16 | Mcneil-Ppc, Inc. | The combination of topical nasal antihistamines and topical nasal steroids |
| DE19947234A1 (de) * | 1999-09-30 | 2001-04-05 | Asta Medica Ag | Neue Kombination von Loteprednol und Antihistaminika |
| CN1376066A (zh) * | 1999-11-18 | 2002-10-23 | 爱尔康公司 | H1拮抗剂和安全类固醇的治疗眼病的用途 |
-
2002
- 2002-11-18 AT AT02804694T patent/ATE317268T1/de active
- 2002-11-18 CN CNA028240197A patent/CN1599625A/zh active Pending
- 2002-11-18 MX MXPA04005417A patent/MXPA04005417A/es active IP Right Grant
- 2002-11-18 PL PL02369630A patent/PL369630A1/xx not_active Application Discontinuation
- 2002-11-18 KR KR1020047007701A patent/KR20050044550A/ko not_active Ceased
- 2002-11-18 US US10/497,619 patent/US20040242638A1/en not_active Abandoned
- 2002-11-18 CA CA002468749A patent/CA2468749A1/en not_active Abandoned
- 2002-11-18 WO PCT/US2002/036915 patent/WO2003049770A1/en not_active Ceased
- 2002-11-18 BR BR0214643-6A patent/BR0214643A/pt not_active IP Right Cessation
- 2002-11-18 AU AU2002366567A patent/AU2002366567B2/en not_active Ceased
- 2002-11-18 DK DK02804694T patent/DK1467762T3/da active
- 2002-11-18 DE DE60209154T patent/DE60209154T2/de not_active Expired - Lifetime
- 2002-11-18 ES ES02804694T patent/ES2258175T3/es not_active Expired - Lifetime
- 2002-11-18 EP EP02804694A patent/EP1467762B1/de not_active Expired - Lifetime
- 2002-11-18 JP JP2003550819A patent/JP2005511724A/ja active Pending
-
2004
- 2004-05-18 ZA ZA2004/03813A patent/ZA200403813B/en unknown
-
2006
- 2006-05-02 CY CY20061100563T patent/CY1105607T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005511724A (ja) | 2005-04-28 |
| ZA200403813B (en) | 2005-07-27 |
| CN1599625A (zh) | 2005-03-23 |
| AU2002366567B2 (en) | 2006-11-16 |
| DK1467762T3 (da) | 2006-04-10 |
| KR20050044550A (ko) | 2005-05-12 |
| US20040242638A1 (en) | 2004-12-02 |
| EP1467762B1 (de) | 2006-02-08 |
| BR0214643A (pt) | 2004-11-03 |
| WO2003049770A1 (en) | 2003-06-19 |
| CA2468749A1 (en) | 2003-06-19 |
| MXPA04005417A (es) | 2004-10-11 |
| AU2002366567A1 (en) | 2003-06-23 |
| ES2258175T3 (es) | 2006-08-16 |
| DE60209154T2 (de) | 2006-08-10 |
| EP1467762A1 (de) | 2004-10-20 |
| CY1105607T1 (el) | 2010-07-28 |
| DE60209154D1 (de) | 2006-04-20 |
| PL369630A1 (en) | 2005-05-02 |
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| UEP | Publication of translation of european patent specification |
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