ATE318834T1 - Lipide mit aminoxygruppe - Google Patents
Lipide mit aminoxygruppeInfo
- Publication number
- ATE318834T1 ATE318834T1 AT01270543T AT01270543T ATE318834T1 AT E318834 T1 ATE318834 T1 AT E318834T1 AT 01270543 T AT01270543 T AT 01270543T AT 01270543 T AT01270543 T AT 01270543T AT E318834 T1 ATE318834 T1 AT E318834T1
- Authority
- AT
- Austria
- Prior art keywords
- lipids
- aminooxy group
- group
- acting
- provides
- Prior art date
Links
- -1 AMINOOXY GROUP Chemical group 0.000 title abstract 2
- 150000002632 lipids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000837 carbohydrate group Chemical group 0.000 abstract 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2000/004767 WO2001048233A1 (en) | 1999-12-23 | 2000-12-12 | Viral core protein-cationic lipid-nucleic acid-delivery complexes |
| GB0113781A GB2372502B (en) | 2000-12-12 | 2001-06-06 | Carbohydrate compounds containing cholesterol and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE318834T1 true ATE318834T1 (de) | 2006-03-15 |
Family
ID=26243759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01270543T ATE318834T1 (de) | 2000-12-12 | 2001-12-05 | Lipide mit aminoxygruppe |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1351972B1 (de) |
| JP (2) | JP2004522722A (de) |
| CN (2) | CN1524125A (de) |
| AT (1) | ATE318834T1 (de) |
| AU (3) | AU2002220894A1 (de) |
| CA (2) | CA2431896A1 (de) |
| DE (1) | DE60117465T2 (de) |
| ES (1) | ES2259007T3 (de) |
| RU (2) | RU2290409C2 (de) |
| WO (2) | WO2002048170A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0129121D0 (en) * | 2001-12-05 | 2002-01-23 | Ic Vec Ltd | Compound |
| WO2006115416A2 (en) * | 2005-04-25 | 2006-11-02 | Ge Healthcare As | Liposomes |
| JP5069920B2 (ja) * | 2007-02-08 | 2012-11-07 | 公益財団法人東京都医学総合研究所 | マンノース6−リン酸−ポリエチレングリコール結合体 |
| GB2458473A (en) | 2008-03-17 | 2009-09-23 | Imuthes Ltd | 3'-O-allyl- and 3'-O-carboxymethyl- 2'-aminosaccharide derivatives, & amides thereof with peptides, as adjuvants |
| GB0908963D0 (en) | 2009-05-22 | 2009-07-01 | Imuthes Ltd | Compositions |
| JP5936002B2 (ja) | 2010-11-19 | 2016-06-15 | 北海道公立大学法人 札幌医科大学 | 組合わせ医薬製剤 |
| CZ307452B6 (cs) * | 2016-11-03 | 2018-09-05 | Vysoká škola chemicko-technologická v Praze | Aminooxylipidy pro konstrukci samoskladných liposomálních systémů umožňujících jejich následnou modifikaci biologicky funkčními molekulami |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL31160A0 (en) * | 1967-12-04 | 1969-01-29 | Bayer Ag | Basically substituted oximes of 5h-dibenzo-(a,d)-10,11-dihydro-cyclohepten-5-one and their production |
| NL6818074A (de) * | 1968-12-17 | 1970-06-19 | ||
| CH574396A5 (de) * | 1969-12-29 | 1976-04-15 | Richter Gedeon Vegyeszet | |
| US4189431A (en) * | 1975-08-04 | 1980-02-19 | The Board of Trustees of Leland Stanford Junior University | Alkinyl terminating groups in biogenetic-like cyclizations to steroids |
| US5283185A (en) * | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
| US5510510A (en) * | 1994-05-10 | 1996-04-23 | Bristol-Meyers Squibb Company | Inhibitors of farnesyl protein transferase |
| DE69727384T2 (de) * | 1996-05-24 | 2004-11-04 | IC-VEC Ltd. | Polykatonische sterin-derivate zur transfektion |
| DE69736840T2 (de) * | 1996-12-24 | 2007-08-09 | Sirna Therapeutics, Inc., Boulder | Synthese von nukleosiden und polynukleotiden |
-
2001
- 2001-12-05 RU RU2003120455/04A patent/RU2290409C2/ru not_active IP Right Cessation
- 2001-12-05 WO PCT/GB2001/005385 patent/WO2002048170A1/en not_active Ceased
- 2001-12-05 ES ES01270543T patent/ES2259007T3/es not_active Expired - Lifetime
- 2001-12-05 CN CNA018226000A patent/CN1524125A/zh active Pending
- 2001-12-05 AT AT01270543T patent/ATE318834T1/de not_active IP Right Cessation
- 2001-12-05 CA CA002431896A patent/CA2431896A1/en not_active Abandoned
- 2001-12-05 JP JP2002550095A patent/JP2004522722A/ja active Pending
- 2001-12-05 CN CNB018225276A patent/CN100482676C/zh not_active Expired - Fee Related
- 2001-12-05 WO PCT/GB2001/005383 patent/WO2002048380A2/en not_active Ceased
- 2001-12-05 EP EP01270543A patent/EP1351972B1/de not_active Expired - Lifetime
- 2001-12-05 RU RU2003120456/15A patent/RU2003120456A/ru not_active Application Discontinuation
- 2001-12-05 JP JP2002549701A patent/JP2004520301A/ja active Pending
- 2001-12-05 AU AU2002220894A patent/AU2002220894A1/en not_active Abandoned
- 2001-12-05 CA CA002364392A patent/CA2364392A1/en not_active Abandoned
- 2001-12-05 AU AU2002222128A patent/AU2002222128B2/en not_active Ceased
- 2001-12-05 DE DE60117465T patent/DE60117465T2/de not_active Expired - Lifetime
- 2001-12-05 AU AU2212802A patent/AU2212802A/xx active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1524125A (zh) | 2004-08-25 |
| AU2002220894A1 (en) | 2002-06-24 |
| DE60117465T2 (de) | 2006-11-02 |
| AU2212802A (en) | 2002-06-24 |
| WO2002048380A2 (en) | 2002-06-20 |
| RU2003120455A (ru) | 2005-01-10 |
| RU2003120456A (ru) | 2005-01-27 |
| DE60117465D1 (de) | 2006-04-27 |
| RU2290409C2 (ru) | 2006-12-27 |
| CA2364392A1 (en) | 2002-06-12 |
| CA2431896A1 (en) | 2002-06-20 |
| EP1351972A1 (de) | 2003-10-15 |
| WO2002048380A3 (en) | 2002-10-24 |
| JP2004520301A (ja) | 2004-07-08 |
| ES2259007T3 (es) | 2006-09-16 |
| JP2004522722A (ja) | 2004-07-29 |
| CN100482676C (zh) | 2009-04-29 |
| EP1351972B1 (de) | 2006-03-01 |
| HK1057048A1 (en) | 2004-03-12 |
| CN1489597A (zh) | 2004-04-14 |
| AU2002222128B2 (en) | 2007-06-21 |
| WO2002048170A1 (en) | 2002-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE429901T1 (de) | Selbstformende thermodynamisch stabile liposome | |
| WO2001095884A3 (en) | Liposomal benzoquinazoline thymidylate synthase inhibitor formulations | |
| WO2002072011A3 (en) | Stabilized therapeutic and imaging agents | |
| EA200300337A1 (ru) | Полиарилкарбоксамиды, применимые в качестве агентов, снижающих содержание липидов | |
| MA26886A1 (fr) | Acides malonamiques et leurs derives, utiles comme ligands de recepteurs thyroidiens. | |
| TR200102856T1 (tr) | Antitümör ajanları olarak C7 ester ikameli taksanlar. | |
| AU1833600A (en) | Cannabimimetic lipid amides as useful medications | |
| MY126897A (en) | Anticonvulsant derivatives useful for preventing the development of type ii diabetes mellitus and syndrome x | |
| BR9604825A (pt) | Citostáticos modificados por carboidratos | |
| SE9600647D0 (sv) | Ny användning | |
| AU3874300A (en) | Dynamic ad targeting by an internet server | |
| ATE318834T1 (de) | Lipide mit aminoxygruppe | |
| DK0930077T3 (da) | Cyclodextrinpræparater indeholdende et avermectin- eller milbemycinderivat | |
| DE60041351D1 (de) | Gssytem | |
| WO2000003724A1 (en) | Preparations for immunotherapy for cancer having bacterial somatic constituent as the active ingredient | |
| IT1281228B1 (it) | Macchina operatrice, in particolare macchina impacchettatrice per sigarette, o simili. | |
| IT1262269B (it) | Macchina confezionatrice, in particolare macchina impacchettatrice, di sigarette o simili. | |
| ATE345778T1 (de) | (ester)-lysolecithine in liposomen | |
| EA200000160A1 (ru) | Новые соли с полезными органолептическими свойствами | |
| AU2002222695A1 (en) | Novel 4'-demethyl-4'-o-substituted-1-deoxypodophyllotoxin derivative and geometric isomer thereof, process for the preparation thereof and anti-cancer composition comprising the same | |
| AU3315200A (en) | 1,5-anhydro-d-fructose substituted with a hydrophobic group for use as anti-oxidant and/or emulsifier | |
| ATE211383T1 (de) | Topische aciclovir-zubereitung | |
| AU7384401A (en) | Active substance conjugates with intracellularly active ligands | |
| IT1309303B1 (it) | Macchina impacchettarice di sigarette. | |
| IT1304044B1 (it) | Macchina confezionatrice di sigarette. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |