ATE318928T1 - Verfahren zum nachweis von serine/threonine kinase aktivität - Google Patents
Verfahren zum nachweis von serine/threonine kinase aktivitätInfo
- Publication number
- ATE318928T1 ATE318928T1 AT01980238T AT01980238T ATE318928T1 AT E318928 T1 ATE318928 T1 AT E318928T1 AT 01980238 T AT01980238 T AT 01980238T AT 01980238 T AT01980238 T AT 01980238T AT E318928 T1 ATE318928 T1 AT E318928T1
- Authority
- AT
- Austria
- Prior art keywords
- kinase activity
- threonine kinase
- detecting
- detecting serine
- serine
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 101001059454 Homo sapiens Serine/threonine-protein kinase MARK2 Proteins 0.000 title 1
- 102100028904 Serine/threonine-protein kinase MARK2 Human genes 0.000 title 1
- 102000009516 Protein Serine-Threonine Kinases Human genes 0.000 abstract 2
- 108010009341 Protein Serine-Threonine Kinases Proteins 0.000 abstract 2
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00117457A EP1182263A1 (de) | 2000-08-11 | 2000-08-11 | Verfahren zum Nachweis einer Threonin- oder Serinkinasenaktivität |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE318928T1 true ATE318928T1 (de) | 2006-03-15 |
Family
ID=8169514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01980238T ATE318928T1 (de) | 2000-08-11 | 2001-08-08 | Verfahren zum nachweis von serine/threonine kinase aktivität |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20030235873A1 (de) |
| EP (2) | EP1182263A1 (de) |
| AT (1) | ATE318928T1 (de) |
| AU (1) | AU2002212133A1 (de) |
| DE (1) | DE60117591T2 (de) |
| DK (1) | DK1328657T3 (de) |
| WO (1) | WO2002014542A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7195884B2 (en) | 2002-07-19 | 2007-03-27 | Promega Corp. | Methods and kits for transferases |
| US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US7381825B2 (en) | 2003-03-17 | 2008-06-03 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| GB2402938B (en) * | 2003-06-17 | 2005-11-09 | Medical Res Council | Kinase assay |
| EP1824831A2 (de) | 2004-12-16 | 2007-08-29 | Takeda San Diego, Inc. | Histondeacetylase-inhibitoren |
| EP1896436A2 (de) | 2005-05-11 | 2008-03-12 | Takeda San Diego, Inc. | Inhibitoren der histondeacetylase |
| EA200800321A1 (ru) | 2005-07-14 | 2008-06-30 | Такеда Сан Диего, Инк. | Ингибиторы гистондеацетилазы |
| US20080227222A1 (en) * | 2007-03-13 | 2008-09-18 | Cullum Malford E | Method for the detection of target molecules by fluorescence polarization using peptide mimics |
| GB0822010D0 (en) * | 2008-12-02 | 2009-01-07 | Imp Innovations Ltd | Assay |
| CN107454899B (zh) | 2014-10-27 | 2020-05-29 | 大学健康网络 | Ripk2抑制剂及用其治疗癌症的方法 |
| CN108535309B (zh) * | 2018-04-16 | 2020-06-09 | 安徽工业大学 | 一种原位测量低碳合金钢中Fe3C析出量的方法 |
| CN114088945A (zh) * | 2021-10-19 | 2022-02-25 | 山东师范大学 | 组蛋白乙酰化修饰酶的hat和/或hct活性的检测方法和抑制剂筛选方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4537861A (en) * | 1983-02-03 | 1985-08-27 | Elings Virgil B | Apparatus and method for homogeneous immunoassay |
| US6596476B1 (en) * | 1989-12-22 | 2003-07-22 | Abbott Laboratories | Hepatitis C assay |
| US5733734A (en) * | 1991-08-14 | 1998-03-31 | The Trustees Of The University Of Pennsylvania | Method of screening for Alzheimer's disease or disease associated with the accumulation of paired helical filaments |
| US20010004522A1 (en) * | 1997-10-28 | 2001-06-21 | Thomas J. Burke | Kinase activity measurement using fluorescence polarization |
| ATE248189T1 (de) * | 1997-11-07 | 2003-09-15 | Vasopharm Biotech Gmbh | Antikörper gegen vasp (vasodilator-stimulated phosphoprotein), hybridomzellen für deren gewinnung, und deren verwendung |
| DK1036192T3 (da) * | 1997-12-05 | 2003-06-10 | Upjohn Co | Fluorescensbaserede screeningsanalyser med høj hastighedforproteinkinaser og phosphataser |
-
2000
- 2000-08-11 EP EP00117457A patent/EP1182263A1/de not_active Withdrawn
-
2001
- 2001-08-08 AU AU2002212133A patent/AU2002212133A1/en not_active Abandoned
- 2001-08-08 DK DK01980238T patent/DK1328657T3/da active
- 2001-08-08 AT AT01980238T patent/ATE318928T1/de not_active IP Right Cessation
- 2001-08-08 DE DE60117591T patent/DE60117591T2/de not_active Expired - Lifetime
- 2001-08-08 EP EP01980238A patent/EP1328657B1/de not_active Expired - Lifetime
- 2001-08-08 WO PCT/EP2001/009186 patent/WO2002014542A2/en not_active Ceased
- 2001-08-13 US US10/344,509 patent/US20030235873A1/en not_active Abandoned
-
2009
- 2009-07-20 US US12/505,680 patent/US20100021939A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1328657A2 (de) | 2003-07-23 |
| DE60117591D1 (de) | 2006-04-27 |
| EP1328657B1 (de) | 2006-03-01 |
| US20100021939A1 (en) | 2010-01-28 |
| AU2002212133A1 (en) | 2002-02-25 |
| EP1182263A1 (de) | 2002-02-27 |
| DK1328657T3 (da) | 2006-07-03 |
| WO2002014542A3 (en) | 2003-05-08 |
| DE60117591T2 (de) | 2006-12-28 |
| WO2002014542A2 (en) | 2002-02-21 |
| US20030235873A1 (en) | 2003-12-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69827557D1 (de) | Vorrichtung zum Ausrichten von Teilen. | |
| DE60231968D1 (de) | Vorrichtung zum autentifizieren von organismen | |
| DE60027711D1 (de) | Verbesserte vorrichtung zum nachweis von myokardischämie | |
| DE60312422D1 (de) | Verbessertes Verfahren zum Einbetten von Dickschichtkomponenten | |
| DE60206536D1 (de) | Vorrichtung zum Halten von Schrauben | |
| DE60032438D1 (de) | Verbessertes Verfahren zum Einbetten von passiven Bauteilen | |
| DE60138486D1 (de) | Verfahren zum nachweis von liganden | |
| DE60213710D1 (de) | Vorrichtung zur Planarisierung von Wafern | |
| DE69417504D1 (de) | Vorrichtung zum nachweis von oberflächenfehlern | |
| DE60019885D1 (de) | Vorrichtung zum Reparieren von Rädern | |
| ATE318928T1 (de) | Verfahren zum nachweis von serine/threonine kinase aktivität | |
| DE69930404D1 (de) | Methode zum nachweis von analyten | |
| DE69923189D1 (de) | Vorrichtung zum Spannen von Risern | |
| DE60214645D1 (de) | Vorrichtung zum Detektieren von magnetischer Flüssigkeit | |
| DE60136355D1 (de) | Verfahren zum entwickeln von werkzeugen | |
| DE59804574D1 (de) | Vorrichtung zum Glätten von Hemden | |
| DE50105519D1 (de) | Vorrichtung zum Aufnehmen von Mikrodissektaten | |
| DE50111035D1 (de) | Verfahren zur detektion des von einer probe kommenden lichtes | |
| DE50202905D1 (de) | Verfahren zum löten von werkstücken | |
| EP1305625A4 (de) | Verfahren zum immunnachweis von epitopen | |
| DE50213031D1 (de) | Verfahren zum sortieren von sendungen auf automatischen sortiereinrichtungen | |
| DE60106395D1 (de) | Verfahren zum lesen von elektronischen etiketten mittels gleichzeitiger identifizierung ihres kodes | |
| DE60216594D1 (de) | Vorrichtung zum aufkonzentrieren von schlamm | |
| DE50014979D1 (de) | Datenverarbeitungsvorrichtung zum parallelen Verarbeiten von unabhängigen Prozessen (Threads) | |
| DE50310455D1 (de) | Vorrichtung zum Ausrichten von blattförmigen Gegenständen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |