ATE319715T1 - Antikonvulsive pseudofructopyranose sulfamate - Google Patents

Antikonvulsive pseudofructopyranose sulfamate

Info

Publication number
ATE319715T1
ATE319715T1 AT95904333T AT95904333T ATE319715T1 AT E319715 T1 ATE319715 T1 AT E319715T1 AT 95904333 T AT95904333 T AT 95904333T AT 95904333 T AT95904333 T AT 95904333T AT E319715 T1 ATE319715 T1 AT E319715T1
Authority
AT
Austria
Prior art keywords
pseudofructopyranose
sulfamates
anticonvulsive
disclosed
compound
Prior art date
Application number
AT95904333T
Other languages
English (en)
Inventor
Michael J Costanzo
Bruce E Maryanoff
David F Mccomsey
Samuel O Nortey
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/337,597 external-priority patent/US5498629A/en
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE319715T1 publication Critical patent/ATE319715T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D497/00Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Confectionery (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
AT95904333T 1993-12-23 1994-12-15 Antikonvulsive pseudofructopyranose sulfamate ATE319715T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17339993A 1993-12-23 1993-12-23
US08/337,597 US5498629A (en) 1993-12-23 1994-11-10 Anticonvulsant pseudofructopyranose sulfamates

Publications (1)

Publication Number Publication Date
ATE319715T1 true ATE319715T1 (de) 2006-03-15

Family

ID=26869093

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95904333T ATE319715T1 (de) 1993-12-23 1994-12-15 Antikonvulsive pseudofructopyranose sulfamate

Country Status (13)

Country Link
EP (1) EP0736029B1 (de)
JP (1) JP3555032B2 (de)
AT (1) ATE319715T1 (de)
AU (1) AU695336B2 (de)
CA (1) CA2179733C (de)
DE (1) DE69434652T2 (de)
DK (1) DK0736029T3 (de)
ES (1) ES2260761T3 (de)
IL (1) IL112098A (de)
NZ (1) NZ277725A (de)
PT (1) PT736029E (de)
RU (1) RU2139875C1 (de)
WO (1) WO1995017406A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000061138A1 (en) * 1999-04-08 2000-10-19 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful in treating chronic neurodegenerative disorders
JP2003505465A (ja) 1999-07-26 2003-02-12 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 急性虚血により引き起こされる神経変性の処置において有用な三環式単糖誘導体
DK1471871T3 (da) * 2001-02-02 2007-09-17 Ortho Mcneil Pharm Inc Behandling af neurologisk dysfunktion omfattende fructopyranosesulfamater og erytropoietin
WO2003039563A1 (en) * 2001-11-06 2003-05-15 Ortho-Mcneil Pharmaceutical Inc. Treatment and prevention of paresthesia comprising co-therapy with anticonvulsant derivatives and potassium
US7060725B2 (en) * 2002-05-13 2006-06-13 Janssen Pharmaceutica N.V. Substituted sulfamate anticonvulsant derivatives
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
JP2008545650A (ja) 2005-05-20 2008-12-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ スルファミド誘導体の製造方法
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8492431B2 (en) 2005-12-19 2013-07-23 Janssen Pharmaceutica, N.V. Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity
US8716231B2 (en) 2005-12-19 2014-05-06 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
EP2026790A2 (de) 2006-05-19 2009-02-25 Janssen Pharmaceutica, N.V. Kombinationstherapie zur behandlung von epilepsie und assoziierten erkrankungen
US8809385B2 (en) 2008-06-23 2014-08-19 Janssen Pharmaceutica Nv Crystalline form of (2S)-(-)-N-(6-chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-sulfamide
US8815939B2 (en) 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
WO2015088271A1 (en) * 2013-12-12 2015-06-18 Bio-Pharm Solutions, Co., Ltd. Sulfamate derivative compound for use in preventing or treating epilepsy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997585A (en) * 1974-12-30 1976-12-14 Ortho Pharmaceutical Corporation Aliphatic sulfamates
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
US4792569A (en) * 1987-08-27 1988-12-20 Mcneilab, Inc. Anticonvulsant phenethyl sulfamates
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates

Also Published As

Publication number Publication date
EP0736029B1 (de) 2006-03-08
AU695336B2 (en) 1998-08-13
IL112098A0 (en) 1995-03-15
NZ277725A (en) 1998-04-27
AU1306795A (en) 1995-07-10
DE69434652D1 (de) 2006-05-04
DK0736029T3 (da) 2006-05-15
JP3555032B2 (ja) 2004-08-18
JPH09507070A (ja) 1997-07-15
CA2179733A1 (en) 1995-06-29
DE69434652T2 (de) 2007-03-01
PT736029E (pt) 2006-05-31
EP0736029A1 (de) 1996-10-09
RU2139875C1 (ru) 1999-10-20
WO1995017406A1 (en) 1995-06-29
IL112098A (en) 1997-07-13
ES2260761T3 (es) 2006-11-01
CA2179733C (en) 2007-03-27

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