ATE320260T1 - Schwefelhaltige phosphonoformat-derivate und deren verwendung. - Google Patents
Schwefelhaltige phosphonoformat-derivate und deren verwendung.Info
- Publication number
- ATE320260T1 ATE320260T1 AT99933950T AT99933950T ATE320260T1 AT E320260 T1 ATE320260 T1 AT E320260T1 AT 99933950 T AT99933950 T AT 99933950T AT 99933950 T AT99933950 T AT 99933950T AT E320260 T1 ATE320260 T1 AT E320260T1
- Authority
- AT
- Austria
- Prior art keywords
- hsv
- derivatives
- compounds
- prodrugs
- proposed
- Prior art date
Links
- ZJAOAACCNHFJAH-UHFFFAOYSA-N phosphonoformic acid Chemical class OC(=O)P(O)(O)=O ZJAOAACCNHFJAH-UHFFFAOYSA-N 0.000 title abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title 1
- 229910052717 sulfur Inorganic materials 0.000 title 1
- 239000011593 sulfur Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229940002612 prodrug Drugs 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- 108700025333 4'-azido-Phe(6)- herpes simplex virus H2 (6-15) Proteins 0.000 abstract 1
- 241000709661 Enterovirus Species 0.000 abstract 1
- 208000007766 Kaposi sarcoma Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000004097 bone metabolism Effects 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000006454 hepatitis Diseases 0.000 abstract 1
- 231100000283 hepatitis Toxicity 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3886—Acids containing the structure -C(=X)-P(=X)(XH)2 or NC-P(=X)(XH)2, (X = O, S, Se)
- C07F9/3891—Acids containing the structure -C(=X)-P(=X)(XH)2, (X = O, S, Se)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4062—Esters of acids containing the structure -C(=X)-P(=X)(XR)2 or NC-P(=X)(XR)2, (X = O, S, Se)
- C07F9/4065—Esters of acids containing the structure -C(=X)-P(=X)(XR)2, (X = O, S, Se)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/42—Halides thereof
- C07F9/425—Acid or estermonohalides thereof, e.g. RP(=X)(YR)(Hal) (X, Y = O, S; R = H, or hydrocarbon group)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9265098P | 1998-07-13 | 1998-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE320260T1 true ATE320260T1 (de) | 2006-04-15 |
Family
ID=22234346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99933950T ATE320260T1 (de) | 1998-07-13 | 1999-07-13 | Schwefelhaltige phosphonoformat-derivate und deren verwendung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6441214B1 (de) |
| EP (1) | EP1094821B1 (de) |
| AT (1) | ATE320260T1 (de) |
| AU (1) | AU4989099A (de) |
| CA (1) | CA2336791C (de) |
| DE (1) | DE69930387T2 (de) |
| ES (1) | ES2259838T3 (de) |
| WO (1) | WO2000002566A1 (de) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3033891A (en) * | 1959-11-27 | 1962-05-08 | Monsanto Chemicals | Mono salts of o-hydrocarbyl-carboalkylthiol phosphonic acids |
| US4033749A (en) * | 1973-07-23 | 1977-07-05 | E. I, Du Pont De Nemours And Company | Alkoxycarbonylphosphonic acid derivative brush control agents |
| US3943201A (en) * | 1973-07-23 | 1976-03-09 | E. I. Du Pont De Nemours And Comapny | Alkoxy carboxycarbonylphosphonic acid esters |
| UST986003I4 (en) | 1979-02-21 | 1979-09-04 | Method for controlling herbaceous weeds | |
| US5183812A (en) | 1989-06-21 | 1993-02-02 | Mckenna Charles E | Preparation and use of thiophosphonates and thio-analogues of phosphonoformic acid |
| US5072032A (en) | 1989-06-21 | 1991-12-10 | Mckenna Charles E | Preparation and use of thiophosphonates and thio-analogues of phosphonoformic acid |
| EP0831842A4 (de) * | 1995-06-06 | 1998-08-19 | Univ Southern California | Verfahren und mittel zur hemmung der vermehrung des cytomegalovirus |
| US5869469A (en) | 1997-08-18 | 1999-02-09 | Queen's University At Kingston | Phosphonocarboxylate compounds for treating amyloidosis |
-
1999
- 1999-07-13 AU AU49890/99A patent/AU4989099A/en not_active Abandoned
- 1999-07-13 WO PCT/US1999/015775 patent/WO2000002566A1/en not_active Ceased
- 1999-07-13 US US09/352,237 patent/US6441214B1/en not_active Expired - Fee Related
- 1999-07-13 CA CA2336791A patent/CA2336791C/en not_active Expired - Fee Related
- 1999-07-13 AT AT99933950T patent/ATE320260T1/de not_active IP Right Cessation
- 1999-07-13 EP EP99933950A patent/EP1094821B1/de not_active Expired - Lifetime
- 1999-07-13 DE DE69930387T patent/DE69930387T2/de not_active Expired - Fee Related
- 1999-07-13 ES ES99933950T patent/ES2259838T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69930387D1 (de) | 2006-05-11 |
| US6441214B1 (en) | 2002-08-27 |
| EP1094821B1 (de) | 2006-03-15 |
| CA2336791A1 (en) | 2000-01-20 |
| DE69930387T2 (de) | 2006-12-07 |
| CA2336791C (en) | 2010-01-26 |
| WO2000002566A1 (en) | 2000-01-20 |
| ES2259838T3 (es) | 2006-10-16 |
| EP1094821A4 (de) | 2002-04-10 |
| AU4989099A (en) | 2000-02-01 |
| EP1094821A1 (de) | 2001-05-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU644095B2 (en) | Antiviral compounds | |
| WO1998004290A3 (en) | Compositions comprising an inducing agent and an anti-viral agent for the treatment of blood, viral and cellular disorders | |
| MY117892A (en) | Therapeutic compounds | |
| DK1914237T3 (da) | Antivirale fosfonatesterforbindelser | |
| FI20001231A7 (fi) | 2-Deoksi-2,3-didehydro-N-asetyylineuramiinihapon johdannaisia ja niiden analogeja ja niiden käyttö antiviraalisina aineina | |
| FR2816838B1 (fr) | Utilisation de derives de l'acide 2-oxothiazolidine- 4-carboxylique comme agents prodesquamants | |
| ATE116637T1 (de) | Sulfonische stilbenderivate zur behandlung von viruserkrankungen. | |
| DE69624813D1 (de) | Robustaflavon und dessen derivate als antivirales mittel | |
| ES2109260T3 (es) | Eritrocitos transformados, procedimiento para prepararlos y su utilizacion en composiciones farmaceuticas. | |
| BR9916041A (pt) | Composto, composição farmacêutica, e, métodospara inibir a replicação de um vìrus do herpes epara tratar um paciente sofrendo de uma infecçãopor vìrus do herpes | |
| NZ324380A (en) | Therapeutic benzimidazole compounds and their use in treatment of virus infections | |
| ATE253368T1 (de) | Verwendung von bisphosphonaten zur prophylaxe und zur behandlung von infektiösen prozessen | |
| DE69731483D1 (de) | Beta-l-dioxolanuridin-analoge zur behandlung und vorbeugung von durch ebv, vzv bzw. hv-8 verursachten viralen infektionen | |
| BR9916046A (pt) | Composto, composição farmacêutica, e, processos para inibir a replicação de um vìrus herpes e para tratamento de um paciente que sofra de uma infecção do vìrus herpes | |
| BR9814053A (pt) | Diésteres lipofìlicos de agentes de quelação | |
| ATE320260T1 (de) | Schwefelhaltige phosphonoformat-derivate und deren verwendung. | |
| TR199900523T2 (xx) | Vir�s k�kenli hastal�klar�n tedavisi i�in farmas�tik bile�imler. | |
| BR9916084A (pt) | Composto, composição farmacêutica, e, processos para inibir a replicação de um vìrus da herpes, e para tratar um paciente sofrendo de uma infecção por vìrus da herpes | |
| RU94016333A (ru) | Лекарственное средство для лечения вирусных заболеваний | |
| DE69422980D1 (de) | Extrakte von Piliostigma thonningii, deren Verwendung und diese enthaltende Zubereitungen | |
| HK1084335A (en) | Compositions comprising an inducing agent and an anti-viral agent for the treatment of blood, viral and cellular disorders | |
| AR025145A1 (es) | Derivados de tiourea que contienen diaminopiridina, composicion farmaceutica que los contienen, y el uso de dichos derivados para la manufactura de unmedicamento para tratar virus herpes | |
| DOP2005000261A (es) | Compuestos de 3h-oxazolo y 3h-tiazolo [4,5-d] pirrimidin-2-ona 3,5-disustituida y 3,5,7-trisustituida y profarmacos de los mismo |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1094821 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |