ATE320420T1 - Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver - Google Patents

Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver

Info

Publication number: ATE320420T1
Authority: AT; Austria
Prior art keywords: group; ring; optically active; hydrogen atom; atom
Prior art date: 1999-10-22

Application number

AT00969902T

Other languages

English (en)

Inventor

Isao Aoki

Mari Adachi

Mitsuru Kawada

Toru Yamano

Naohiro Taya

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-22

Filing date

2000-10-19

Publication date

2006-04-15

2000-10-19 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2006-04-15 Application granted granted Critical

2006-04-15 Publication of ATE320420T1 publication Critical patent/ATE320420T1/de

Links

230000003287 optical effect Effects 0.000 title abstract 2
UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical class C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
229910052799 carbon Inorganic materials 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 3
125000001183 hydrocarbyl group Chemical group 0.000 abstract 3
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
206010006187 Breast cancer Diseases 0.000 abstract 1
208000026310 Breast neoplasm Diseases 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
206010036976 Prostatism Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001721 carbon Chemical group 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000002790 naphthalenes Chemical class 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1
125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5027—Polyphosphines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/6574—Esters of oxyacids of phosphorus
- C07F9/65744—Esters of oxyacids of phosphorus condensed with carbocyclic or heterocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Dermatology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT00969902T 1999-10-22 2000-10-19 Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver ATE320420T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP30157699		1999-10-22
JP30157099		1999-10-22

Publications (1)

Publication Number	Publication Date
ATE320420T1 true ATE320420T1 (de)	2006-04-15

Family

ID=26562752

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00969902T ATE320420T1 (de)	1999-10-22	2000-10-19	Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver

Country Status (7)

Country	Link
US (1)	US6800778B1 (de)
EP (1)	EP1227085B1 (de)
AT (1)	ATE320420T1 (de)
AU (1)	AU7949900A (de)
CA (1)	CA2388483A1 (de)
DE (1)	DE60026725T2 (de)
WO (1)	WO2001030763A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2328973A1 (en)	1998-04-23	1999-10-28	Akio Ojida	Naphthalene derivatives, their production and use
PE20010781A1 (es)	1999-10-22	2001-08-08	Takeda Chemical Industries Ltd	Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion
JP4725760B2 (ja) *	2000-03-13	2011-07-13	東ソー株式会社	光学活性リン酸エステル誘導体及びその用途
DE60144246D1 (de) *	2000-11-20	2011-04-28	Takeda Pharmaceutical	Imidazolderivate, verfahren zu deren herstellung und deren verwendung
US6878831B2 (en)	2000-12-28	2005-04-12	Takeda Chemical Industries, Ltd.	Process for preparing optically active 2,3-dihydrobenzofuran compounds
GB0521582D0 (en)	2005-10-22	2005-11-30	Depuy Int Ltd	An implant for supporting a spinal column
GB0600662D0 (en)	2006-01-13	2006-02-22	Depuy Int Ltd	Spinal support rod kit
US8348952B2 (en)	2006-01-26	2013-01-08	Depuy International Ltd.	System and method for cooling a spinal correction device comprising a shape memory material for corrective spinal surgery
GB0720762D0 (en)	2007-10-24	2007-12-05	Depuy Spine Sorl	Assembly for orthopaedic surgery
CZ201535A3 (cs) *	2015-01-21	2016-08-03	Zentiva, K.S.	Nové možnosti chirální resoluce bedaquilinu
CN107602464B (zh) *	2016-07-12	2020-02-18	宜昌人福药业有限责任公司	利用光学拆分制备双芳基喹啉类抗生素的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT951631B (it) *	1971-03-18	1973-07-10	Richardson Merrell Spa	Composti utili per la separazione di isomeri ottici geometrici e strutturali e relativo procedimen to di sintesi
NL8403224A (nl)	1984-10-24	1986-05-16	Oce Andeno Bv	Dioxafosforinanen, de bereiding ervan en de toepassing voor het splitsen van optisch actieve verbindingen.
GB8719886D0 (en) *	1987-08-22	1987-09-30	British Petroleum Co Plc	Carboxylic acid esters/acids
NL1004346C2 (nl) *	1996-10-23	1998-04-24	Dsm Nv	Werkwijze voor het scheiden van een mengsel van enantiomeren in een geschikt oplosmiddel.
CA2328973A1 (en) *	1998-04-23	1999-10-28	Akio Ojida	Naphthalene derivatives, their production and use

2000
- 2000-10-19 DE DE60026725T patent/DE60026725T2/de not_active Expired - Lifetime
- 2000-10-19 EP EP00969902A patent/EP1227085B1/de not_active Expired - Lifetime
- 2000-10-19 WO PCT/JP2000/007282 patent/WO2001030763A1/ja not_active Ceased
- 2000-10-19 US US10/111,211 patent/US6800778B1/en not_active Expired - Fee Related
- 2000-10-19 CA CA002388483A patent/CA2388483A1/en not_active Abandoned
- 2000-10-19 AU AU79499/00A patent/AU7949900A/en not_active Abandoned
- 2000-10-19 AT AT00969902T patent/ATE320420T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP1227085B1 (de)	2006-03-15
US6800778B1 (en)	2004-10-05
EP1227085A1 (de)	2002-07-31
CA2388483A1 (en)	2001-05-03
WO2001030763A1 (en)	2001-05-03
DE60026725T2 (de)	2006-09-07
DE60026725D1 (de)	2006-05-11
AU7949900A (en)	2001-05-08
EP1227085A4 (de)	2003-06-18

Legal Events

Date	Code	Title	Description
2006-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE3775882D1 (de)	1992-02-20	Substituierte 6-fluor-4-oxo-1,4-dihydrochinolin-3-carbonsaeuren ; deren derivate; diese verbindung enthaltende pharmazeutische zubereitungen und verfahren zur herstellung dieser verbindungen.
BR9914451A (pt)	2001-05-22	Composto de oxazol, processo para sua preparação, composição farmacêutica compreendendo dito composto, uso da composição e métodos de tratamento
DK1583524T3 (da)	2006-12-27	Bis(thiohydrazidamid)-forbindelser til behandling af multilægemiddel-resistent cancer
BR0211262A (pt)	2004-07-20	Tienopirimidinodionas e seu uso na modulação de doenças autoimunes
BR0010391A (pt)	2002-07-02	Composto, composição farmacêutica, método de preparação de um composto, e, uso de um composto
ES2054826T3 (es)	1994-08-16	Peptidos con actividad inhibidora de colagenasa.
ATE264268T1 (de)	2004-04-15	Verfahren zur herstellung von zsm-5 und zsm-11
ATE320420T1 (de)	2006-04-15	Verfahren zur herstellung von optisch aktiven naphthalinderivaten und darin eingesetzte optische resolver
AT384424B (de)	1987-11-10	Verfahren zur herstellung von neuen 3-hydroxy-2-oxo-pyrrolidinderivaten und ihren salzen
ATE251624T1 (de)	2003-10-15	Granulatimide-derivate zur behandlung von krebs
ATE211474T1 (de)	2002-01-15	Galanthamin derivate, verfahren zu ihrer herstellung und ihre verwendung als medikamente
ES2073258T3 (es)	1995-08-01	Nuevos derivados de la urea, su preparacion y su aplicacion en terapeutica.
ATE204868T1 (de)	2001-09-15	2-aryl-3-aminoaryloxynaphthylverbindungen, zwischenverbindungen, zusammensetzungen und verfahren
BR0005557A (pt)	2001-07-17	Compostos diidrofuro[3,4-b] quinolin-1-ona, processo para a preparação dos mesmos e composições farmacêuticas contendo os mesmos
DE69820481D1 (de)	2004-01-22	Verfahren zur herstellung von cholecalciferol-derivaten und zwischenverbindungen
ATE48276T1 (de)	1989-12-15	1,6-naphthyridin-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel.
DE3752124D1 (de)	1997-11-13	Verfahren zur Herstellung von Penem Derivaten und Zwischenprodukte zu dieser Herstellung
ATE246682T1 (de)	2003-08-15	Benzothiazinderivate
ATE290869T1 (de)	2005-04-15	Verwendung von vitamin d derivaten zur herstellung eines medikaments zur behandlung von bösartigen tumormetastase
DE69808922D1 (de)	2002-11-28	Thiazolobenzoheterocyclen, ihre herstellung und diese enthaltende phatrmazeutische zubereitungen
DK0555351T3 (da)	1995-06-06	Oxysulfonylcarbamater
ATE8389T1 (de)	1984-07-15	Amino-alkoxy-pyrazole, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
ATE118346T1 (de)	1995-03-15	Verwendung von bis(4-hydroxyphenylthio)methan- derivaten zur behandlung von diabetes mellitus.
BR9815448A (pt)	2001-10-16	Derivados de imino-aza-antraciclinona para o tratamento de amiloidose
DE3880861D1 (de)	1993-06-17	1-dethia-2-thia-cephalosporansaeurederivate, verfahren zur herstellung, ihre verwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen.