ATE321356T1 - Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrens - Google Patents

Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrens

Info

Publication number
ATE321356T1
ATE321356T1 AT02718000T AT02718000T ATE321356T1 AT E321356 T1 ATE321356 T1 AT E321356T1 AT 02718000 T AT02718000 T AT 02718000T AT 02718000 T AT02718000 T AT 02718000T AT E321356 T1 ATE321356 T1 AT E321356T1
Authority
AT
Austria
Prior art keywords
ions
ecd
trapping
electron
electron capture
Prior art date
Application number
AT02718000T
Other languages
English (en)
Inventor
Roman Zubarev
Original Assignee
Univ Syddansk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Syddansk filed Critical Univ Syddansk
Application granted granted Critical
Publication of ATE321356T1 publication Critical patent/ATE321356T1/de

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/0054—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by an electron beam, e.g. electron impact dissociation, electron capture dissociation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
AT02718000T 2001-03-22 2002-03-22 Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrens ATE321356T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27762101P 2001-03-22 2001-03-22
DKPA200100478 2001-03-22
US34836802P 2002-01-16 2002-01-16
DKPA200200069 2002-01-16

Publications (1)

Publication Number Publication Date
ATE321356T1 true ATE321356T1 (de) 2006-04-15

Family

ID=27439840

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02718000T ATE321356T1 (de) 2001-03-22 2002-03-22 Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrens

Country Status (6)

Country Link
US (1) US6958472B2 (de)
EP (1) EP1371083B1 (de)
AT (1) ATE321356T1 (de)
CA (1) CA2441776A1 (de)
DE (1) DE60210056T2 (de)
WO (1) WO2002078048A1 (de)

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US20020115056A1 (en) * 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
DE10297199T5 (de) * 2001-09-10 2004-08-12 Varian Australia Pty. Ltd., Mulgrave Vorrichtung und Verfahren zur Elementaren Massenspektrometrie
AU2002328668B2 (en) * 2001-09-10 2006-09-28 Agilent Technologies Australia (M) Pty Ltd Apparatus and method for elemental mass spectrometry
DE10213652B4 (de) * 2002-03-27 2008-02-21 Bruker Daltonik Gmbh Verfahren zur Bestrahlung von Ionen in einer Ionenzyklotronresonanz-Falle mit Elektronen und/oder Photonen
EP1549923B1 (de) * 2002-05-31 2012-10-17 PerkinElmer Health Sciences, Inc. Fragmentierungsverfahren für die massenspektrometrie
US6919562B1 (en) 2002-05-31 2005-07-19 Analytica Of Branford, Inc. Fragmentation methods for mass spectrometry
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
CA2800040C (en) * 2002-10-29 2015-12-29 Target Discovery, Inc. Method for increasing ionization efficiency in mass spectroscopy
US6958475B1 (en) * 2003-01-09 2005-10-25 Colby Steven M Electron source
JP2006521006A (ja) * 2003-03-03 2006-09-14 ブリガム・ヤング・ユニバーシティ 直交加速飛行時間型質量分析のための新規な電子イオン化源
US7227133B2 (en) 2003-06-03 2007-06-05 The University Of North Carolina At Chapel Hill Methods and apparatus for electron or positron capture dissociation
DE10325579B4 (de) * 2003-06-05 2007-10-11 Bruker Daltonik Gmbh Ionenfragmentierung durch Elektroneneinfang in linearen Ionenfallen
DE10325582B4 (de) 2003-06-05 2009-01-15 Bruker Daltonik Gmbh Ionenfragmentierung durch Elektroneneinfang in Hochfrequenz-Ionenfallen mit magnetischer Führung der Elektronen
US6800851B1 (en) * 2003-08-20 2004-10-05 Bruker Daltonik Gmbh Electron-ion fragmentation reactions in multipolar radiofrequency fields
US7026613B2 (en) 2004-01-23 2006-04-11 Thermo Finnigan Llc Confining positive and negative ions with fast oscillating electric potentials
GB0404106D0 (en) * 2004-02-24 2004-03-31 Shimadzu Res Lab Europe Ltd An ion trap and a method for dissociating ions in an ion trap
GB2414855A (en) * 2004-03-30 2005-12-07 Thermo Finnigan Llc Ion fragmentation by electron capture
US7038200B2 (en) * 2004-04-28 2006-05-02 Bruker Daltonik Gmbh Ion cyclotron resonance mass spectrometer
DE102004025262A1 (de) * 2004-05-19 2005-12-22 Bruker Daltonik Gmbh Massenspektrometer mit Ionenfragmentierung durch Elektroneneinfang
JP4806214B2 (ja) 2005-01-28 2011-11-02 株式会社日立ハイテクノロジーズ 電子捕獲解離反応装置
DE102005005743B4 (de) * 2005-02-07 2007-06-06 Bruker Daltonik Gmbh Ionenfragmentierung durch Beschuss mit Neutralteilchen
GB0523806D0 (en) * 2005-11-23 2006-01-04 Micromass Ltd Mass spectrometer
GB0523811D0 (en) * 2005-11-23 2006-01-04 Micromass Ltd Mass stectrometer
GB2432712B (en) * 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
JP4621744B2 (ja) 2005-11-28 2011-01-26 株式会社日立製作所 イオンガイド装置、イオン反応装置、及び質量分析装置
GB0609253D0 (en) * 2006-05-10 2006-06-21 Micromass Ltd Mass spectrometer
WO2008092259A1 (en) * 2007-01-31 2008-08-07 University Of Manitoba Electron capture dissociation in a mass spectrometer
DE102007017236B4 (de) * 2007-04-12 2011-03-31 Bruker Daltonik Gmbh Einführung von Ionen in ein Magnetfeld
US8723113B2 (en) * 2008-05-30 2014-05-13 The State of Oregon Acting by and through the State Board of Higher Education of behalf of Oregon State University Radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers
WO2010002819A1 (en) 2008-07-01 2010-01-07 Waters Technologies Corporation Stacked-electrode peptide-fragmentation device
US7952067B2 (en) * 2008-10-06 2011-05-31 Quest Diagnostics Investments Incorporated Methods for detecting vitamin C by mass spectrometry
WO2010044370A1 (ja) * 2008-10-14 2010-04-22 株式会社日立製作所 質量分析装置および質量分析方法
US8575542B1 (en) * 2012-04-18 2013-11-05 Bruker Daltonics, Inc. Method and device for gas-phase ion fragmentation
EP2883237B1 (de) * 2012-08-16 2020-11-25 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Elektromagnetostatische elektroneninduzierte dissoziationszelle
US9105454B2 (en) * 2013-11-06 2015-08-11 Agilent Technologies, Inc. Plasma-based electron capture dissociation (ECD) apparatus and related systems and methods
JP6835210B2 (ja) * 2017-04-10 2021-02-24 株式会社島津製作所 イオン分析装置及びイオン解離方法
WO2020230063A1 (en) * 2019-05-13 2020-11-19 Dh Technologies Development Pte. Ltd. Background reduction in top-down antibody analysis
JP7424508B2 (ja) * 2020-11-02 2024-01-30 株式会社島津製作所 イオン分析装置

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US4731533A (en) 1986-10-15 1988-03-15 Vestec Corporation Method and apparatus for dissociating ions by electron impact
US4988869A (en) 1989-08-21 1991-01-29 The Regents Of The University Of California Method and apparatus for electron-induced dissociation of molecular species
US5340983A (en) 1992-05-18 1994-08-23 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method and apparatus for mass analysis using slow monochromatic electrons
US5374828A (en) * 1993-09-15 1994-12-20 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Electron reversal ionizer for detection of trace species using a spherical cathode
DE10058706C1 (de) * 2000-11-25 2002-02-28 Bruker Daltonik Gmbh Ionenfragmentierung durch Elektroneneinfang in Hochfrequenz-Ionenfallen
DE10213652B4 (de) * 2002-03-27 2008-02-21 Bruker Daltonik Gmbh Verfahren zur Bestrahlung von Ionen in einer Ionenzyklotronresonanz-Falle mit Elektronen und/oder Photonen

Also Published As

Publication number Publication date
WO2002078048A1 (en) 2002-10-03
US6958472B2 (en) 2005-10-25
DE60210056T2 (de) 2006-11-16
EP1371083A1 (de) 2003-12-17
EP1371083B1 (de) 2006-03-22
DE60210056D1 (de) 2006-05-11
US20040155180A1 (en) 2004-08-12
CA2441776A1 (en) 2002-10-03

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