ATE321356T1 - Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrens - Google Patents
Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrensInfo
- Publication number
- ATE321356T1 ATE321356T1 AT02718000T AT02718000T ATE321356T1 AT E321356 T1 ATE321356 T1 AT E321356T1 AT 02718000 T AT02718000 T AT 02718000T AT 02718000 T AT02718000 T AT 02718000T AT E321356 T1 ATE321356 T1 AT E321356T1
- Authority
- AT
- Austria
- Prior art keywords
- ions
- ecd
- trapping
- electron
- electron capture
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 230000005264 electron capture Effects 0.000 title abstract 2
- 238000004949 mass spectrometry Methods 0.000 title abstract 2
- 150000002500 ions Chemical class 0.000 abstract 6
- 238000001211 electron capture detection Methods 0.000 abstract 4
- 238000010894 electron beam technology Methods 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 1
- 230000005686 electrostatic field Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
- H01J49/0054—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by an electron beam, e.g. electron impact dissociation, electron capture dissociation
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27762101P | 2001-03-22 | 2001-03-22 | |
| DKPA200100478 | 2001-03-22 | ||
| US34836802P | 2002-01-16 | 2002-01-16 | |
| DKPA200200069 | 2002-01-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE321356T1 true ATE321356T1 (de) | 2006-04-15 |
Family
ID=27439840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02718000T ATE321356T1 (de) | 2001-03-22 | 2002-03-22 | Massenspektrometrisches verfahren mit elektroneneinfang durch ionen und massenspektrometer zum durchführen des verfahrens |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6958472B2 (de) |
| EP (1) | EP1371083B1 (de) |
| AT (1) | ATE321356T1 (de) |
| CA (1) | CA2441776A1 (de) |
| DE (1) | DE60210056T2 (de) |
| WO (1) | WO2002078048A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020115056A1 (en) * | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
| GB2396961B (en) * | 2001-09-10 | 2005-05-11 | Varian Australia | Apparatus and method for elemental mass spectrometry |
| AU2002328668B2 (en) * | 2001-09-10 | 2006-09-28 | Agilent Technologies Australia (M) Pty Ltd | Apparatus and method for elemental mass spectrometry |
| DE10213652B4 (de) * | 2002-03-27 | 2008-02-21 | Bruker Daltonik Gmbh | Verfahren zur Bestrahlung von Ionen in einer Ionenzyklotronresonanz-Falle mit Elektronen und/oder Photonen |
| US6919562B1 (en) | 2002-05-31 | 2005-07-19 | Analytica Of Branford, Inc. | Fragmentation methods for mass spectrometry |
| WO2003102545A2 (en) * | 2002-05-31 | 2003-12-11 | Analytica Of Branford, Inc. | Fragmentation methods for mass spectrometry |
| GB0305796D0 (en) | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
| EP1579187B1 (de) | 2002-10-29 | 2012-12-19 | Target Discovery, Inc. | Verfahren zur erhöhung der ionisierungseffizienz bei der massenspektroskopie |
| US6958475B1 (en) * | 2003-01-09 | 2005-10-25 | Colby Steven M | Electron source |
| JP2006521006A (ja) * | 2003-03-03 | 2006-09-14 | ブリガム・ヤング・ユニバーシティ | 直交加速飛行時間型質量分析のための新規な電子イオン化源 |
| US7227133B2 (en) * | 2003-06-03 | 2007-06-05 | The University Of North Carolina At Chapel Hill | Methods and apparatus for electron or positron capture dissociation |
| DE10325579B4 (de) * | 2003-06-05 | 2007-10-11 | Bruker Daltonik Gmbh | Ionenfragmentierung durch Elektroneneinfang in linearen Ionenfallen |
| DE10325582B4 (de) * | 2003-06-05 | 2009-01-15 | Bruker Daltonik Gmbh | Ionenfragmentierung durch Elektroneneinfang in Hochfrequenz-Ionenfallen mit magnetischer Führung der Elektronen |
| US6800851B1 (en) * | 2003-08-20 | 2004-10-05 | Bruker Daltonik Gmbh | Electron-ion fragmentation reactions in multipolar radiofrequency fields |
| US7026613B2 (en) | 2004-01-23 | 2006-04-11 | Thermo Finnigan Llc | Confining positive and negative ions with fast oscillating electric potentials |
| GB0404106D0 (en) * | 2004-02-24 | 2004-03-31 | Shimadzu Res Lab Europe Ltd | An ion trap and a method for dissociating ions in an ion trap |
| GB2414855A (en) * | 2004-03-30 | 2005-12-07 | Thermo Finnigan Llc | Ion fragmentation by electron capture |
| US7038200B2 (en) * | 2004-04-28 | 2006-05-02 | Bruker Daltonik Gmbh | Ion cyclotron resonance mass spectrometer |
| DE102004025262A1 (de) * | 2004-05-19 | 2005-12-22 | Bruker Daltonik Gmbh | Massenspektrometer mit Ionenfragmentierung durch Elektroneneinfang |
| JP4806214B2 (ja) | 2005-01-28 | 2011-11-02 | 株式会社日立ハイテクノロジーズ | 電子捕獲解離反応装置 |
| DE102005005743B4 (de) * | 2005-02-07 | 2007-06-06 | Bruker Daltonik Gmbh | Ionenfragmentierung durch Beschuss mit Neutralteilchen |
| GB0523806D0 (en) * | 2005-11-23 | 2006-01-04 | Micromass Ltd | Mass spectrometer |
| GB2432712B (en) * | 2005-11-23 | 2007-12-27 | Micromass Ltd | Mass spectrometer |
| GB0523811D0 (en) * | 2005-11-23 | 2006-01-04 | Micromass Ltd | Mass stectrometer |
| US8049169B2 (en) * | 2005-11-28 | 2011-11-01 | Hitachi, Ltd. | Ion guide device, ion reactor, and mass analyzer |
| GB0609253D0 (en) * | 2006-05-10 | 2006-06-21 | Micromass Ltd | Mass spectrometer |
| WO2008092259A1 (en) * | 2007-01-31 | 2008-08-07 | University Of Manitoba | Electron capture dissociation in a mass spectrometer |
| DE102007017236B4 (de) * | 2007-04-12 | 2011-03-31 | Bruker Daltonik Gmbh | Einführung von Ionen in ein Magnetfeld |
| US8723113B2 (en) * | 2008-05-30 | 2014-05-13 | The State of Oregon Acting by and through the State Board of Higher Education of behalf of Oregon State University | Radio-frequency-free hybrid electrostatic/magnetostatic cell for transporting, trapping, and dissociating ions in mass spectrometers |
| WO2010002819A1 (en) | 2008-07-01 | 2010-01-07 | Waters Technologies Corporation | Stacked-electrode peptide-fragmentation device |
| US7952067B2 (en) * | 2008-10-06 | 2011-05-31 | Quest Diagnostics Investments Incorporated | Methods for detecting vitamin C by mass spectrometry |
| US20110204221A1 (en) * | 2008-10-14 | 2011-08-25 | Hiroyuki Satake | Mass spectrometer and method of mass spectrometry |
| US8575542B1 (en) * | 2012-04-18 | 2013-11-05 | Bruker Daltonics, Inc. | Method and device for gas-phase ion fragmentation |
| US9305760B2 (en) * | 2012-08-16 | 2016-04-05 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Electron source for an RF-free electronmagnetostatic electron-induced dissociation cell and use in a tandem mass spectrometer |
| US9105454B2 (en) * | 2013-11-06 | 2015-08-11 | Agilent Technologies, Inc. | Plasma-based electron capture dissociation (ECD) apparatus and related systems and methods |
| US11075067B2 (en) * | 2017-04-10 | 2021-07-27 | Shimadzu Corporation | Ion analysis device and ion dissociation method |
| JP7645809B2 (ja) * | 2019-05-13 | 2025-03-14 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | トップダウン抗体解析における背景低減 |
| US20230386814A1 (en) * | 2020-11-02 | 2023-11-30 | Shimadzu Corporation | Ion Analyzer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4731533A (en) * | 1986-10-15 | 1988-03-15 | Vestec Corporation | Method and apparatus for dissociating ions by electron impact |
| US4988869A (en) * | 1989-08-21 | 1991-01-29 | The Regents Of The University Of California | Method and apparatus for electron-induced dissociation of molecular species |
| US5340983A (en) * | 1992-05-18 | 1994-08-23 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Method and apparatus for mass analysis using slow monochromatic electrons |
| US5374828A (en) * | 1993-09-15 | 1994-12-20 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Electron reversal ionizer for detection of trace species using a spherical cathode |
| DE10058706C1 (de) * | 2000-11-25 | 2002-02-28 | Bruker Daltonik Gmbh | Ionenfragmentierung durch Elektroneneinfang in Hochfrequenz-Ionenfallen |
| DE10213652B4 (de) * | 2002-03-27 | 2008-02-21 | Bruker Daltonik Gmbh | Verfahren zur Bestrahlung von Ionen in einer Ionenzyklotronresonanz-Falle mit Elektronen und/oder Photonen |
-
2002
- 2002-03-22 US US10/471,454 patent/US6958472B2/en not_active Expired - Fee Related
- 2002-03-22 EP EP02718000A patent/EP1371083B1/de not_active Expired - Lifetime
- 2002-03-22 CA CA002441776A patent/CA2441776A1/en not_active Abandoned
- 2002-03-22 WO PCT/DK2002/000195 patent/WO2002078048A1/en not_active Ceased
- 2002-03-22 AT AT02718000T patent/ATE321356T1/de not_active IP Right Cessation
- 2002-03-22 DE DE60210056T patent/DE60210056T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60210056T2 (de) | 2006-11-16 |
| EP1371083A1 (de) | 2003-12-17 |
| CA2441776A1 (en) | 2002-10-03 |
| EP1371083B1 (de) | 2006-03-22 |
| WO2002078048A1 (en) | 2002-10-03 |
| DE60210056D1 (de) | 2006-05-11 |
| US20040155180A1 (en) | 2004-08-12 |
| US6958472B2 (en) | 2005-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |