ATE321549T1 - Bromierte hexahydroxybiphenylderivate - Google Patents

Bromierte hexahydroxybiphenylderivate

Info

Publication number
ATE321549T1
ATE321549T1 AT96921528T AT96921528T ATE321549T1 AT E321549 T1 ATE321549 T1 AT E321549T1 AT 96921528 T AT96921528 T AT 96921528T AT 96921528 T AT96921528 T AT 96921528T AT E321549 T1 ATE321549 T1 AT E321549T1
Authority
AT
Austria
Prior art keywords
derivatives
hexahydroxybiphenyl
brominated
ddb
hiv activity
Prior art date
Application number
AT96921528T
Other languages
English (en)
Inventor
Kuo-Hsiung Lee
Yoshiki Kashiwada
Lan Xie
Louis Mark Cosentino
Mark Manak
Jing-Xi Xie
Tan Street Nong
Yung-Chi Cheng
Robert E Kilkuskie
Original Assignee
Univ North Carolina
Panacos Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina, Panacos Pharmaceuticals Inc filed Critical Univ North Carolina
Application granted granted Critical
Publication of ATE321549T1 publication Critical patent/ATE321549T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
AT96921528T 1995-06-07 1996-06-07 Bromierte hexahydroxybiphenylderivate ATE321549T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/477,939 US5612341A (en) 1995-06-07 1995-06-07 Brominated hexahydroxybiphenyl derivatives

Publications (1)

Publication Number Publication Date
ATE321549T1 true ATE321549T1 (de) 2006-04-15

Family

ID=23897936

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921528T ATE321549T1 (de) 1995-06-07 1996-06-07 Bromierte hexahydroxybiphenylderivate

Country Status (9)

Country Link
US (1) US5612341A (de)
EP (1) EP0837677B1 (de)
AT (1) ATE321549T1 (de)
AU (1) AU6273596A (de)
DE (1) DE69635990T2 (de)
DK (1) DK0837677T3 (de)
ES (1) ES2264140T3 (de)
PT (1) PT837677E (de)
WO (1) WO1996040111A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1332131A2 (de) 2000-11-07 2003-08-06 Bristol-Myers Squibb Company Säurederivate und ihre verwendung als inhibitoren von serinproteasen
US6906192B2 (en) 2000-11-07 2005-06-14 Bristol Myers Squibb Company Processes for the preparation of acid derivatives useful as serine protease inhibitors
JP2004517060A (ja) 2000-11-07 2004-06-10 ブリストルーマイヤーズ スクイブ カンパニー セリンプロテアーゼ抑制剤として有用な酸誘導体
US6768007B2 (en) 2001-03-13 2004-07-27 Panacos Pharmaceuticals, Inc. Substituted 3′,4′-di-O-camphanoyl-(+)-cis-khellactone analogs, compositions thereof, and methods for using thereof
CN1173968C (zh) * 2002-10-11 2004-11-03 常俊标 卤代六羟基联苯衍生物的制法及药物用途
WO2008057420A2 (en) 2006-11-03 2008-05-15 Panacos Pharmaceuticals, Inc. Extended triterpene derivatives
CN102532150A (zh) * 2012-02-27 2012-07-04 中国药科大学 一种烷氧基二苯并吖庚因类化合物、其制备方法及医药用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR880701233A (ko) * 1986-05-27 1988-07-26 쓰무라 아끼라 새로운 비페닐 유도체와 그의 제조 방법 및 용도
US5264594A (en) * 1986-05-27 1993-11-23 Tsumura & Co. Biphenyl derivative and preparation and use thereof
HU202855B (en) * 1986-06-13 1991-04-29 Tsumura & Co Process for producing new biphenyl derivatives and pharmaceutical compositions containing them as active components
JPH0660142B2 (ja) * 1989-06-02 1994-08-10 田辺製薬株式会社 ビフェニル誘導体、その製法及びその合成中間体
US4868207A (en) * 1988-07-28 1989-09-19 Taisho Pharmaceutical Co., Ltd. Bis (methylenedioxy) biphenyl compounds useful for the treatment of liver diseases
WO1990004968A1 (en) * 1988-10-31 1990-05-17 University Of North Carolina At Chapel Hill Inhibition of human retroviruses
US5159069A (en) * 1988-12-20 1992-10-27 Yamanouchi Pharmaceutical Co., Ltd. Sulfated tannins and their salts
US5233057A (en) * 1989-06-02 1993-08-03 Tanabe Seiyaku Co., Ltd. Biphenyl derivatives, process for preparing the same and intermediates therefor
US5182404A (en) * 1989-06-02 1993-01-26 Tanabe Seiyake Co., Ltd. Biphenyl derivatives, process for preparing the same and intermediates therefor
AU5850894A (en) * 1992-12-23 1994-07-19 Procept, Inc. Novel agents for inhibition of hiv infectivity and use therefor

Also Published As

Publication number Publication date
DE69635990D1 (de) 2006-05-18
EP0837677B1 (de) 2006-03-29
EP0837677A4 (de) 1999-12-15
DE69635990T2 (de) 2006-12-21
WO1996040111A1 (en) 1996-12-19
PT837677E (pt) 2006-08-31
DK0837677T3 (da) 2006-07-31
EP0837677A1 (de) 1998-04-29
AU6273596A (en) 1996-12-30
US5612341A (en) 1997-03-18
ES2264140T3 (es) 2006-12-16

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