ATE322016T1 - Screeningsverfahren zur änderung zirkadiane- rhythmus-eiweisse - Google Patents
Screeningsverfahren zur änderung zirkadiane- rhythmus-eiweisseInfo
- Publication number
- ATE322016T1 ATE322016T1 AT00939629T AT00939629T ATE322016T1 AT E322016 T1 ATE322016 T1 AT E322016T1 AT 00939629 T AT00939629 T AT 00939629T AT 00939629 T AT00939629 T AT 00939629T AT E322016 T1 ATE322016 T1 AT E322016T1
- Authority
- AT
- Austria
- Prior art keywords
- alter
- ability
- directed
- phosphorylation
- circadian rhythm
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000027288 circadian rhythm Effects 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000012216 screening Methods 0.000 title 1
- 102000007001 Period Circadian Proteins Human genes 0.000 abstract 3
- 108010047728 Period Circadian Proteins Proteins 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000026731 phosphorylation Effects 0.000 abstract 3
- 238000006366 phosphorylation reaction Methods 0.000 abstract 3
- 230000015556 catabolic process Effects 0.000 abstract 2
- 238000006731 degradation reaction Methods 0.000 abstract 2
- 230000003993 interaction Effects 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Electrophonic Musical Instruments (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32774599A | 1999-06-08 | 1999-06-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE322016T1 true ATE322016T1 (de) | 2006-04-15 |
Family
ID=23277866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00939629T ATE322016T1 (de) | 1999-06-08 | 2000-06-07 | Screeningsverfahren zur änderung zirkadiane- rhythmus-eiweisse |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6555328B1 (de) |
| EP (1) | EP1183541B1 (de) |
| JP (1) | JP4583682B2 (de) |
| KR (1) | KR100722176B1 (de) |
| AT (1) | ATE322016T1 (de) |
| AU (1) | AU767800B2 (de) |
| BR (1) | BR0011437A (de) |
| CA (1) | CA2375450C (de) |
| DE (1) | DE60026998T2 (de) |
| IL (2) | IL146729A0 (de) |
| MX (1) | MXPA01011417A (de) |
| NO (3) | NO330241B1 (de) |
| NZ (1) | NZ514603A (de) |
| WO (1) | WO2000075669A1 (de) |
| ZA (1) | ZA200108962B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6476188B1 (en) | 1998-06-19 | 2002-11-05 | The Rockefeller University | Clock gene and methods of use thereof |
| US6436628B1 (en) | 1998-06-19 | 2002-08-20 | The Rockefeller University | Methods of identifying an agent which modulates period and doubletime protein interaction |
| KR100722176B1 (ko) * | 1999-06-08 | 2007-05-29 | 아벤티스 파마슈티칼스 인크. | 일주기 리듬 단백질을 변화시키기 위한 스크리닝 방법 |
| US7659387B1 (en) * | 1999-11-18 | 2010-02-09 | University Of Virginia | Transgenic mammals introduced a Period 1 promoter that confers rhythmical expression |
| GB0103110D0 (en) * | 2000-08-25 | 2001-03-28 | Aventis Pharma Inc | A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1 |
| EP1358315A4 (de) * | 2001-01-11 | 2005-11-16 | Univ Utah Res Found | Identifizierung eines advanced-sleep-phase-syndrom-gens im menschen |
| AU2003278333A1 (en) * | 2002-10-25 | 2004-05-13 | University Of Surrey | Polymorphism in the per3 gene as a indicator in the diagnosis and treatment of circadian rhythm sleep disorders |
| US20060134619A1 (en) * | 2002-11-27 | 2006-06-22 | Louis Ptacek | Casein kinase i epsilon and casein kinase i delta and sleep in humans |
| AU2005277460A1 (en) * | 2004-08-19 | 2006-03-02 | Aventis Pharmaceuticals Inc. | 3-arylthioindole-2-carboxamide derivatives and analogs thereof as inhibitors of casein kinase I epsilon |
| JO2629B1 (en) * | 2004-08-19 | 2012-06-24 | افينتيس فارما سوتيكالز انك | Branched carboxylic acid amides containing thienobirol, carboxylic acid amides containing pyrolithiazole, and the like as kinase inhibitors casein epsilon |
| JO2724B1 (en) * | 2004-08-19 | 2013-09-15 | افينتس فارماسوتيكالز انك | 3-Alternative-5 -6-Amino Alkyl Indole-2-Carboxyl Acid Amide and Related Isotopes as Casein Kinase Inhibitors |
| JP2009538597A (ja) * | 2006-05-31 | 2009-11-12 | 独立行政法人放射線医学総合研究所 | 光誘導性周期的発現遺伝子及び体内時計システムに影響を与える物質のスクリーニング方法 |
| JP5518479B2 (ja) * | 2006-10-25 | 2014-06-11 | ザ ロックフェラー ユニヴァーシティ | Ａβ関連障害の処置のための方法およびその組成物 |
| FR2918986B1 (fr) | 2007-07-19 | 2009-09-04 | Sanofi Aventis Sa | Derives de 6-cycloamino-3-(pyridazin-4-yl)imidazo[1,2-b]- pyridazine, leur preparation et leur application en therapeutique |
| CN105744948B (zh) * | 2013-10-14 | 2020-03-24 | 南京大学 | 进食节律提前综合征的识别方法及其应用 |
| KR101600144B1 (ko) * | 2013-12-20 | 2016-03-04 | 서울대학교산학협력단 | 일주기 리듬 수면장애 및 시차 부적응에 대한 예방 또는 치료제 스크리닝 방법 |
| BR112016016098A2 (pt) | 2014-01-09 | 2017-08-08 | Intracellular Therapies Inc | Compostos orgânicos |
| WO2017083835A1 (en) * | 2015-11-13 | 2017-05-18 | The Trustees Of Columbia University In The City Of New York | Inhibition of tor complex 2 increases immunity against bacterial infection |
| US20250066778A1 (en) * | 2022-01-03 | 2025-02-27 | The Johns Hopkins University | Methods and materials for treating heart attack |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1157137A (ja) * | 1997-08-28 | 1999-03-02 | Sanyo Bussan Kk | 遊技機用特別図柄表示装置 |
| KR100246893B1 (ko) * | 1997-12-29 | 2000-05-01 | 윤종용 | 전자렌지용 도어 |
| AU3976099A (en) * | 1998-05-07 | 1999-11-23 | President & Fellows Of Harvard College, The | Compositions and methods involving regulation of mammalian circadian rhythms |
| KR100722176B1 (ko) * | 1999-06-08 | 2007-05-29 | 아벤티스 파마슈티칼스 인크. | 일주기 리듬 단백질을 변화시키기 위한 스크리닝 방법 |
-
2000
- 2000-06-07 KR KR1020017015764A patent/KR100722176B1/ko not_active Expired - Fee Related
- 2000-06-07 NZ NZ514603A patent/NZ514603A/en not_active IP Right Cessation
- 2000-06-07 EP EP00939629A patent/EP1183541B1/de not_active Expired - Lifetime
- 2000-06-07 AT AT00939629T patent/ATE322016T1/de active
- 2000-06-07 DE DE60026998T patent/DE60026998T2/de not_active Expired - Lifetime
- 2000-06-07 AU AU54689/00A patent/AU767800B2/en not_active Ceased
- 2000-06-07 WO PCT/US2000/015633 patent/WO2000075669A1/en not_active Ceased
- 2000-06-07 MX MXPA01011417A patent/MXPA01011417A/es active IP Right Grant
- 2000-06-07 IL IL14672900A patent/IL146729A0/xx active IP Right Grant
- 2000-06-07 JP JP2001501893A patent/JP4583682B2/ja not_active Expired - Fee Related
- 2000-06-07 CA CA002375450A patent/CA2375450C/en not_active Expired - Fee Related
- 2000-06-07 BR BR0011437-5A patent/BR0011437A/pt not_active Application Discontinuation
- 2000-06-07 US US09/589,462 patent/US6555328B1/en not_active Expired - Lifetime
-
2001
- 2001-10-30 ZA ZA200108962A patent/ZA200108962B/en unknown
- 2001-11-25 IL IL146729A patent/IL146729A/en not_active IP Right Cessation
- 2001-12-06 NO NO20015972A patent/NO330241B1/no not_active IP Right Cessation
-
2010
- 2010-03-23 NO NO20100430A patent/NO20100430L/no not_active Application Discontinuation
- 2010-03-23 NO NO20100431A patent/NO20100431L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100722176B1 (ko) | 2007-05-29 |
| AU5468900A (en) | 2000-12-28 |
| NO330241B1 (no) | 2011-03-14 |
| AU767800B2 (en) | 2003-11-27 |
| US6555328B1 (en) | 2003-04-29 |
| CA2375450C (en) | 2009-04-28 |
| NO20100431L (no) | 2002-02-05 |
| KR20020033101A (ko) | 2002-05-04 |
| NO20100430L (no) | 2002-02-05 |
| JP4583682B2 (ja) | 2010-11-17 |
| JP2003501074A (ja) | 2003-01-14 |
| DE60026998T2 (de) | 2007-04-05 |
| BR0011437A (pt) | 2002-03-05 |
| NO20015972D0 (no) | 2001-12-06 |
| CA2375450A1 (en) | 2000-12-14 |
| WO2000075669A1 (en) | 2000-12-14 |
| EP1183541A1 (de) | 2002-03-06 |
| MXPA01011417A (es) | 2002-06-04 |
| ZA200108962B (en) | 2003-01-30 |
| IL146729A (en) | 2007-06-17 |
| IL146729A0 (en) | 2002-07-25 |
| DE60026998D1 (de) | 2006-05-18 |
| NZ514603A (en) | 2003-10-31 |
| EP1183541B1 (de) | 2006-03-29 |
| NO20015972L (no) | 2002-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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| EEIH | Change in the person of patent owner |