ATE322249T1 - System zur abgabe einer tobramycin-formulierung - Google Patents
System zur abgabe einer tobramycin-formulierungInfo
- Publication number
- ATE322249T1 ATE322249T1 AT02771857T AT02771857T ATE322249T1 AT E322249 T1 ATE322249 T1 AT E322249T1 AT 02771857 T AT02771857 T AT 02771857T AT 02771857 T AT02771857 T AT 02771857T AT E322249 T1 ATE322249 T1 AT E322249T1
- Authority
- AT
- Austria
- Prior art keywords
- delivery system
- formulation delivery
- tobramycin
- less
- tobramycin formulation
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- NLVFBUXFDBBNBW-PBSUHMDJSA-N tobramycin Chemical compound N[C@@H]1C[C@H](O)[C@@H](CN)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](N)[C@H](O)[C@@H](CO)O2)O)[C@H](N)C[C@@H]1N NLVFBUXFDBBNBW-PBSUHMDJSA-N 0.000 title abstract 2
- 229960000707 tobramycin Drugs 0.000 title abstract 2
- 229940126574 aminoglycoside antibiotic Drugs 0.000 abstract 2
- 239000002647 aminoglycoside antibiotic agent Substances 0.000 abstract 2
- 239000000443 aerosol Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29223401P | 2001-05-18 | 2001-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE322249T1 true ATE322249T1 (de) | 2006-04-15 |
Family
ID=23123791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02771857T ATE322249T1 (de) | 2001-05-18 | 2002-05-17 | System zur abgabe einer tobramycin-formulierung |
Country Status (11)
| Country | Link |
|---|---|
| US (8) | US20030143162A1 (de) |
| EP (2) | EP2186508A3 (de) |
| JP (2) | JP2004534763A (de) |
| AT (1) | ATE322249T1 (de) |
| AU (1) | AU2010210026A1 (de) |
| CA (1) | CA2447600C (de) |
| DE (1) | DE60210402T2 (de) |
| DK (1) | DK1320355T3 (de) |
| ES (1) | ES2261735T3 (de) |
| PT (1) | PT1320355E (de) |
| WO (1) | WO2002094217A1 (de) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW465235B (en) | 1998-09-17 | 2001-11-21 | United Video Properties Inc | Electronic program guide with digital storage |
| ATE322249T1 (de) * | 2001-05-18 | 2006-04-15 | Chiron Corp | System zur abgabe einer tobramycin-formulierung |
| US20040022740A1 (en) * | 2001-07-10 | 2004-02-05 | Baker William R. | Macrolide formulations for inhalation and methods of treatment of endobronchial infections |
| EP1424889A4 (de) * | 2001-08-20 | 2008-04-02 | Transave Inc | Verfahren zur behandlung von lungenkarzinomen |
| WO2003053411A1 (en) | 2001-12-19 | 2003-07-03 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| US8245708B2 (en) * | 2002-05-07 | 2012-08-21 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| US7607436B2 (en) * | 2002-05-06 | 2009-10-27 | The Research Foundation Of State University Of New York | Methods, devices and formulations for targeted endobronchial therapy |
| US20040101553A1 (en) * | 2002-08-02 | 2004-05-27 | Transave, Inc. | Platinum aggregates and process for producing the same |
| US9186322B2 (en) * | 2002-08-02 | 2015-11-17 | Insmed Incorporated | Platinum aggregates and process for producing the same |
| AU2002953095A0 (en) * | 2002-11-29 | 2002-12-19 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
| EP3738591A3 (de) | 2003-03-10 | 2021-03-24 | Merck Sharp & Dohme Corp. | Neuartige antibakterielle wirkstoffe |
| EP1673074B1 (de) * | 2003-10-15 | 2007-01-03 | PARI GmbH Spezialisten für effektive Inhalation | Flüssige zubereitung enthaltend tobramycin |
| US20070065522A1 (en) * | 2004-03-18 | 2007-03-22 | Transave, Inc. | Administration of high potency platinum compound formulations by inhalation |
| CN1976711A (zh) * | 2004-03-18 | 2007-06-06 | 特兰萨维股份有限公司 | 通过吸入给药顺铂 |
| WO2005110022A2 (en) | 2004-05-17 | 2005-11-24 | Corus Pharma, Inc. | Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections |
| AU2005245018A1 (en) * | 2004-05-21 | 2005-12-01 | Transave, Inc. | Treatment of lung diseases and pre-lung disease conditions |
| HRP20130076T1 (hr) | 2004-06-18 | 2013-03-31 | Novartis Ag | Formulacije tobramicina za lijeäśenje endobronhijalnih infekcija |
| EP1811963A4 (de) * | 2004-11-08 | 2010-01-06 | Transave Inc | Verfahren zur krebsbehandlung mit intraperitoneal verabreichten platinverbindungsformulierungen auf lipidbasis |
| AU2013206401B2 (en) * | 2005-09-29 | 2016-06-23 | Novartis Ag | Antibiotic formulations, unit doses, kits, and methods |
| JP2009510077A (ja) * | 2005-09-29 | 2009-03-12 | ネクター セラピューティックス | 抗生物質製剤、単位用量、キットおよび方法 |
| US20070190180A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intravenously |
| WO2007056236A2 (en) * | 2005-11-08 | 2007-05-18 | Transave, Inc. | Methods of treating cancer with lipid-based platinum compound formulations administered intravenously |
| US9107824B2 (en) | 2005-11-08 | 2015-08-18 | Insmed Incorporated | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US20070190182A1 (en) * | 2005-11-08 | 2007-08-16 | Pilkiewicz Frank G | Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally |
| US20070122350A1 (en) * | 2005-11-30 | 2007-05-31 | Transave, Inc. | Safe and effective methods of administering therapeutic agents |
| PL1962805T3 (pl) | 2005-12-08 | 2017-01-31 | Insmed Incorporated | Kompozycje środków przeciwzapalnych oparte na lipidach do leczenia infekcji płucnych |
| WO2007070875A1 (en) * | 2005-12-15 | 2007-06-21 | Aerosol Science Laboratories, Inc. | Treatment of active infections and related compositions |
| JP2008199905A (ja) * | 2007-02-16 | 2008-09-04 | Snow Brand Milk Prod Co Ltd | 乳酸菌生残性向上剤 |
| US9453042B2 (en) | 2007-10-25 | 2016-09-27 | Cempra Pharmaceuticals, Inc. | Process for the preparation of macrolide antibacterial agents |
| EP2260510A1 (de) * | 2008-04-02 | 2010-12-15 | Nxp B.V. | Verfahren zur herstellung eines halbleiterbauelements und halbleiterbauelement |
| CN107854477A (zh) | 2008-10-24 | 2018-03-30 | 森普拉制药公司 | 使用含三唑的大环内酯治疗抗性疾病的方法 |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| CN108310000A (zh) | 2009-09-10 | 2018-07-24 | 森普拉制药公司 | 治疗疟疾、结核病和mac疾病的方法 |
| US8975386B2 (en) | 2010-03-22 | 2015-03-10 | Cempra Pharmaceuticals, Inc. | Crystalline forms of a macrolide, and uses therefor |
| CN102917708B (zh) | 2010-05-20 | 2015-11-25 | 森普拉制药公司 | 制备大环内酯和酮内酯及其中间体的方法 |
| KR102012418B1 (ko) * | 2010-07-12 | 2019-08-20 | 셀리아 파마슈티칼즈 에이피에스 | 에어로졸화에 의한 토브라마이신의 투여에 의한 폐 감염의 치료 |
| KR20180110181A (ko) | 2010-09-10 | 2018-10-08 | 셈프라 파마슈티컬스, 인크. | 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드 |
| RU2014101763A (ru) | 2011-07-12 | 2015-08-20 | Кардис Фарма Корпорейшн | Композиции комбинаций амикацина и фосфомицина, способы и системы для лечения вентилятор-ассоциированной пневмонии и вентилятор-ассоциированного трахеоброхита |
| US8826904B2 (en) | 2011-07-12 | 2014-09-09 | Cardeas Pharma Corporation | Formulations of aminoglycoside and fosfomycin combinations and methods and systems for treatment of ventilator associated pneumonia (VAP) and ventilator associated tracheal (VAT) bronchitis |
| SG11201405895UA (en) | 2012-03-27 | 2014-10-30 | Cempra Pharmaceuticals Inc | Parenteral formulations for administering macrolide antibiotics |
| GB201208080D0 (en) | 2012-05-09 | 2012-06-20 | Norton Healthcare Ltd | Tobramycin formulation |
| CN115414384A (zh) | 2012-09-04 | 2022-12-02 | 埃莱森制药有限责任公司 | 用顺铂脂质复合物预防癌症的肺部复发 |
| RU2018135921A (ru) | 2012-11-29 | 2019-02-05 | Инсмед Инкорпорейтед | Стабилизированные составы ванкомицина |
| UA117673C2 (uk) | 2013-01-11 | 2018-09-10 | Кселлія Фармасьютікалз Апс | Поліміксини, композиція, спосіб одержання і спосіб застосування (варіанти) |
| US9861616B2 (en) | 2013-03-14 | 2018-01-09 | Cempra Pharmaceuticals, Inc. | Methods for treating respiratory diseases and formulations therefor |
| MX356772B (es) | 2013-03-15 | 2018-06-13 | Cempra Pharmaceuticals Inc | Procesos convergentes para la preparacion de agentes antibacterianos macrolidos. |
| MX376012B (es) | 2014-05-15 | 2025-03-07 | Insmed Inc | Metodos para tratar infecciones pulmonares micobacterianas no tuberculosas. |
| KR20170032348A (ko) | 2014-07-09 | 2017-03-22 | 셀리아 파마슈티칼즈 에이피에스 | 저 치환된 폴리믹신 및 이의 조성물 |
| KR102433278B1 (ko) | 2014-10-03 | 2022-08-16 | 셀리아 파마슈티칼즈 에이피에스 | 조성물 |
| RU2702335C2 (ru) | 2014-10-03 | 2019-10-08 | Кселлия Фармасьютикалз Апс | Ингаляционное устройство |
| US10617703B2 (en) | 2014-12-10 | 2020-04-14 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11793783B2 (en) | 2015-08-05 | 2023-10-24 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US11690815B2 (en) | 2015-08-05 | 2023-07-04 | Cmpd Licensing Llc | Hyperkeratotic skin condition treatments and compositions |
| US11446236B2 (en) | 2015-08-05 | 2022-09-20 | Cmpd Licensing, Llc | Topical antimicrobial compositions and methods of formulating the same |
| US11278590B2 (en) | 2015-08-05 | 2022-03-22 | Cmpd Licensing, Llc | Compositions and methods for treating nail infections |
| US11684567B2 (en) | 2015-08-05 | 2023-06-27 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US10898491B2 (en) | 2015-12-18 | 2021-01-26 | Cmpd Licensing, Llc | Compositions and methods for treating an infection |
| US10898455B2 (en) | 2016-01-07 | 2021-01-26 | Cmpd Licensing, Llc | Urea cream formulations |
| US10525025B2 (en) | 2016-11-17 | 2020-01-07 | Cmpd Licensing, Llc | Compounded compositions and methods for treating pain |
| US9999604B2 (en) | 2016-11-17 | 2018-06-19 | Cmpd Licensing, Llc | Compounded solutions of diclofenac and lidocaine and methods |
| JP7460534B2 (ja) | 2018-03-30 | 2024-04-02 | インスメッド インコーポレイテッド | リポソーム医薬品の連続製造方法 |
| US20210113467A1 (en) | 2018-05-02 | 2021-04-22 | Robert Worsham | Methods for the manufacture of liposomal drug formulations |
| WO2020163416A1 (en) * | 2019-02-05 | 2020-08-13 | Mylan Inc | Devices and methods for tobramycin inhalation treatment |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3993223A (en) | 1974-07-25 | 1976-11-23 | American Home Products Corporation | Dispensing container |
| US4502616A (en) | 1982-01-04 | 1985-03-05 | Health Care Concepts, Inc. | Single use vial |
| GB8801655D0 (en) | 1988-01-26 | 1988-02-24 | Waverley Pharma Ltd | Ampoules |
| DE68904082T2 (de) | 1988-01-28 | 1993-07-29 | Lameplast Srl | Flaeschchenkette fuer pharmazeutische, kosmetische und andere produkte. |
| GB8802349D0 (en) | 1988-02-03 | 1988-03-02 | Waverley Pharma Ltd | Ampoule with luer |
| DE3916840A1 (de) | 1988-09-21 | 1990-03-29 | Bernd Hansen | Ampulle |
| US5409125A (en) | 1989-12-11 | 1995-04-25 | Aktiebolaget Astra | Unit dose container |
| CA2027690A1 (en) | 1990-10-18 | 1992-04-19 | Christian Laing | Plastic ampul |
| FR2687066A1 (fr) | 1992-02-06 | 1993-08-13 | Oreal | Ampoule autocassable. |
| US5508269A (en) | 1994-10-19 | 1996-04-16 | Pathogenesis Corporation | Aminoglycoside formulation for aerosolization |
| US5758637A (en) * | 1995-08-31 | 1998-06-02 | Aerogen, Inc. | Liquid dispensing apparatus and methods |
| US6083922A (en) | 1996-04-02 | 2000-07-04 | Pathogenesis, Corp. | Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis |
| CA2355775A1 (en) | 1998-12-17 | 2000-06-22 | Pathogenesis Corporation | Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic |
| SE9902627D0 (sv) * | 1999-07-08 | 1999-07-08 | Siemens Elema Ab | Medical nebulizer |
| DE19953317C1 (de) | 1999-11-05 | 2001-02-01 | Pari Gmbh | Inhalationsvernebler |
| ATE322249T1 (de) | 2001-05-18 | 2006-04-15 | Chiron Corp | System zur abgabe einer tobramycin-formulierung |
-
2002
- 2002-05-17 AT AT02771857T patent/ATE322249T1/de active
- 2002-05-17 CA CA2447600A patent/CA2447600C/en not_active Expired - Fee Related
- 2002-05-17 US US10/151,701 patent/US20030143162A1/en not_active Abandoned
- 2002-05-17 EP EP09015943A patent/EP2186508A3/de not_active Withdrawn
- 2002-05-17 DK DK02771857T patent/DK1320355T3/da active
- 2002-05-17 WO PCT/US2002/015999 patent/WO2002094217A1/en not_active Ceased
- 2002-05-17 JP JP2002590936A patent/JP2004534763A/ja active Pending
- 2002-05-17 DE DE60210402T patent/DE60210402T2/de not_active Revoked
- 2002-05-17 EP EP02771857A patent/EP1320355B1/de not_active Revoked
- 2002-05-17 PT PT02771857T patent/PT1320355E/pt unknown
- 2002-05-17 ES ES02771857T patent/ES2261735T3/es not_active Expired - Lifetime
-
2003
- 2003-12-22 US US10/743,529 patent/US6890907B2/en not_active Expired - Lifetime
-
2004
- 2004-07-01 US US10/883,143 patent/US20040265241A1/en not_active Abandoned
-
2005
- 2005-05-10 US US11/125,670 patent/US20050207987A1/en not_active Abandoned
- 2005-05-10 US US11/126,108 patent/US20050201947A1/en not_active Abandoned
-
2007
- 2007-10-24 US US11/923,486 patent/US7825095B2/en not_active Expired - Lifetime
-
2009
- 2009-08-07 JP JP2009185305A patent/JP2009269923A/ja active Pending
-
2010
- 2010-08-09 AU AU2010210026A patent/AU2010210026A1/en not_active Abandoned
- 2010-09-17 US US12/884,505 patent/US20110005518A1/en not_active Abandoned
-
2011
- 2011-11-14 US US13/295,228 patent/US8507454B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009269923A (ja) | 2009-11-19 |
| JP2004534763A (ja) | 2004-11-18 |
| DK1320355T3 (da) | 2006-07-31 |
| US20040265241A1 (en) | 2004-12-30 |
| US20080095717A1 (en) | 2008-04-24 |
| EP2186508A2 (de) | 2010-05-19 |
| CA2447600C (en) | 2015-10-20 |
| EP2186508A3 (de) | 2010-08-25 |
| WO2002094217A1 (en) | 2002-11-28 |
| US20050207987A1 (en) | 2005-09-22 |
| US20040131555A1 (en) | 2004-07-08 |
| CA2447600A1 (en) | 2002-11-28 |
| US20030143162A1 (en) | 2003-07-31 |
| PT1320355E (pt) | 2006-08-31 |
| ES2261735T3 (es) | 2006-11-16 |
| US20120101055A1 (en) | 2012-04-26 |
| US6890907B2 (en) | 2005-05-10 |
| US8507454B2 (en) | 2013-08-13 |
| US7825095B2 (en) | 2010-11-02 |
| DE60210402T2 (de) | 2006-12-07 |
| EP1320355A1 (de) | 2003-06-25 |
| DE60210402D1 (de) | 2006-05-18 |
| EP1320355B1 (de) | 2006-04-05 |
| AU2010210026A1 (en) | 2010-09-02 |
| US20050201947A1 (en) | 2005-09-15 |
| US20110005518A1 (en) | 2011-01-13 |
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