ATE322252T1 - Verfahren zur herstellung und sammlung von kristallinen partikeln - Google Patents

Verfahren zur herstellung und sammlung von kristallinen partikeln

Info

Publication number
ATE322252T1
ATE322252T1 AT01943684T AT01943684T ATE322252T1 AT E322252 T1 ATE322252 T1 AT E322252T1 AT 01943684 T AT01943684 T AT 01943684T AT 01943684 T AT01943684 T AT 01943684T AT E322252 T1 ATE322252 T1 AT E322252T1
Authority
AT
Austria
Prior art keywords
producing
crystalline particles
collecting crystalline
particles
collecting
Prior art date
Application number
AT01943684T
Other languages
English (en)
Inventor
Robert William Lancaster
Hardev Singh
Andrew Lewis Theopilus
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE322252T1 publication Critical patent/ATE322252T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
AT01943684T 2000-06-29 2001-06-29 Verfahren zur herstellung und sammlung von kristallinen partikeln ATE322252T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0015981.4A GB0015981D0 (en) 2000-06-29 2000-06-29 Novel process for preparing crystalline particles

Publications (1)

Publication Number Publication Date
ATE322252T1 true ATE322252T1 (de) 2006-04-15

Family

ID=9894682

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01943684T ATE322252T1 (de) 2000-06-29 2001-06-29 Verfahren zur herstellung und sammlung von kristallinen partikeln

Country Status (9)

Country Link
US (1) US20030181432A1 (de)
EP (1) EP1294359B1 (de)
JP (1) JP2004500983A (de)
AT (1) ATE322252T1 (de)
AU (1) AU2001266218A1 (de)
DE (1) DE60118558T2 (de)
ES (1) ES2260236T3 (de)
GB (1) GB0015981D0 (de)
WO (1) WO2002000198A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7498019B2 (en) 2001-05-24 2009-03-03 Alexza Pharmaceuticals, Inc. Delivery of compounds for the treatment of headache through an inhalation route
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Pharmaceuticals, Inc. Delivery of drug esters through an inhalation route
WO2002094241A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of compounds for the treatment of migraine through an inhalation route
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
WO2002094243A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of sumatriptan, frovatriptan or naratriptan through an inhalation route
WO2002094242A1 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of rizatriptan or zolmitriptan through an inhalation route
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
WO2002094238A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of anti-migraine compounds through an inhalation route
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
EP1423096B1 (de) * 2001-08-29 2006-08-16 Dow Global Technologies Inc. Verfahren zur herstellung kristalliner arzneimittelteilchen durch ausfällung
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
JP4748584B2 (ja) * 2003-01-31 2011-08-17 水ｉｎｇ株式会社 晶析法による液中イオンの除去方法及び装置
WO2004076403A1 (en) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Sumatriptan crystalline forms, pharmaceutical compositions and methods
ATE510174T1 (de) 2003-05-21 2011-06-15 Alexza Pharmaceuticals Inc Schlag gezündete unabhängige heizeinheit
GB0406069D0 (en) * 2004-03-17 2004-04-21 Thompson James Process
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
WO2006010078A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Polymorphic form of naratriptan hydrochloride
AU2004322756B2 (en) 2004-08-12 2011-04-14 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
US8420122B2 (en) 2006-04-28 2013-04-16 Merck Sharp & Dohme Corp. Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same
CA2650395A1 (en) * 2006-04-28 2007-11-08 Schering Corporation Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same
JP2010500356A (ja) * 2006-08-09 2010-01-07 グラクソ グループ リミテッド ラクトースの製造方法
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
GB0705159D0 (en) 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) * 2007-06-18 2007-07-25 Prosonix Ltd Process
BR112012017556A2 (pt) * 2010-01-15 2016-08-16 Lithera Inc formulações de torta liofilizada
WO2013009591A1 (en) * 2011-07-08 2013-01-17 Pfizer Limited Process for the preparation of fluticasone propionate form 1
PT3517541T (pt) 2012-05-08 2020-08-28 Nicox Ophthalmics Inc Forma polimórfica de propionato de fluticasona
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
EP2705838A1 (de) * 2012-09-06 2014-03-12 Xspray Microparticles Ab Tiotropium-Zubereitungen
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
JP2018126699A (ja) * 2017-02-09 2018-08-16 水ｉｎｇ株式会社 晶析方法及び晶析装置
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

Family Cites Families (13)

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Publication number Priority date Publication date Assignee Title
US3154395A (en) * 1961-01-30 1964-10-27 Universal Oil Prod Co Continuous fractional crystallization process
US3984409A (en) * 1973-08-09 1976-10-05 Pfizer Inc. Cyclic n-substituted derivatives of 1,4-benzene disulphonamide
NL7501406A (en) * 1975-02-06 1976-08-10 Dso Pharmachim Crystallisation of tetracycline hydrochloride - accelerated by subjecting to high-frequency vibrations, with purer, less toxic prod. formed
CA2044706C (en) * 1990-06-15 2003-02-25 Michael Midler Jr. Crystallization method to improve crystal structure and size
GB9313650D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
EA002039B1 (ru) * 1997-09-03 2001-12-24 Мерк Энд Ко., Инк. Способ повышения оптической чистоты 2r-[1-гидрокси-1-трифторметил-3-циклопропилпропин-2-ил]-4-хлоранилина
JP2001527085A (ja) * 1997-12-29 2001-12-25 クラリオン ファーマスーティカルズ インコーポレイテッド Ｎ−ｈｅｔ置換グリセロホスホエタノールアミン類
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
US6566516B1 (en) * 1998-08-31 2003-05-20 Nof Corporation High purity polysaccharide containing a hydrophobic group and process for producing it
SE9802974D0 (sv) * 1998-09-03 1998-09-03 Astra Ab New crystalline forms
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
AU755470B2 (en) * 1999-01-29 2002-12-12 Bristol-Myers Squibb Company Sonic impinging jet crystallization apparatus and process

Also Published As

Publication number Publication date
ES2260236T3 (es) 2006-11-01
EP1294359A1 (de) 2003-03-26
AU2001266218A1 (en) 2002-01-08
DE60118558T2 (de) 2006-08-24
US20030181432A1 (en) 2003-09-25
DE60118558D1 (de) 2006-05-18
JP2004500983A (ja) 2004-01-15
WO2002000198A1 (en) 2002-01-03
GB0015981D0 (en) 2000-08-23
EP1294359B1 (de) 2006-04-05

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