ATE322252T1 - Verfahren zur herstellung und sammlung von kristallinen partikeln - Google Patents

Verfahren zur herstellung und sammlung von kristallinen partikeln

Info

Publication number
ATE322252T1
ATE322252T1 AT01943684T AT01943684T ATE322252T1 AT E322252 T1 ATE322252 T1 AT E322252T1 AT 01943684 T AT01943684 T AT 01943684T AT 01943684 T AT01943684 T AT 01943684T AT E322252 T1 ATE322252 T1 AT E322252T1
Authority
AT
Austria
Prior art keywords
producing
crystalline particles
collecting crystalline
particles
collecting
Prior art date
Application number
AT01943684T
Other languages
English (en)
Inventor
Robert William Lancaster
Hardev Singh
Andrew Lewis Theopilus
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE322252T1 publication Critical patent/ATE322252T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT01943684T 2000-06-29 2001-06-29 Verfahren zur herstellung und sammlung von kristallinen partikeln ATE322252T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0015981.4A GB0015981D0 (en) 2000-06-29 2000-06-29 Novel process for preparing crystalline particles

Publications (1)

Publication Number Publication Date
ATE322252T1 true ATE322252T1 (de) 2006-04-15

Family

ID=9894682

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01943684T ATE322252T1 (de) 2000-06-29 2001-06-29 Verfahren zur herstellung und sammlung von kristallinen partikeln

Country Status (9)

Country Link
US (1) US20030181432A1 (de)
EP (1) EP1294359B1 (de)
JP (1) JP2004500983A (de)
AT (1) ATE322252T1 (de)
AU (1) AU2001266218A1 (de)
DE (1) DE60118558T2 (de)
ES (1) ES2260236T3 (de)
GB (1) GB0015981D0 (de)
WO (1) WO2002000198A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094241A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of compounds for the treatment of migraine through an inhalation route
WO2002094243A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of sumatriptan, frovatriptan or naratriptan through an inhalation route
US7498019B2 (en) 2001-05-24 2009-03-03 Alexza Pharmaceuticals, Inc. Delivery of compounds for the treatment of headache through an inhalation route
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
WO2002094242A1 (en) 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of rizatriptan or zolmitriptan through an inhalation route
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
JP2005503425A (ja) 2001-05-24 2005-02-03 アレックザ モレキュラー デリヴァリー コーポレイション 所定の吸入ルートによる薬剤エステルの送出
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
WO2002094238A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of anti-migraine compounds through an inhalation route
WO2003032951A1 (en) * 2001-08-29 2003-04-24 Dow Global Technologies Inc. A process for preparing crystalline drug particles by means of precipitation
GB0208608D0 (en) * 2002-04-13 2002-05-22 Glaxo Group Ltd Composition
ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
EP1593417A4 (de) * 2003-01-31 2007-02-28 Ebara Corp Verfahren und vorrichtung zur ionenentfernung aus einer flüssigkeit mittels kristallisierung
WO2004076403A1 (en) * 2003-02-24 2004-09-10 Transform Pharmaceuticals, Inc. Sumatriptan crystalline forms, pharmaceutical compositions and methods
US20040234916A1 (en) 2003-05-21 2004-11-25 Alexza Molecular Delivery Corporation Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
GB0406069D0 (en) * 2004-03-17 2004-04-21 Thompson James Process
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
WO2006010078A2 (en) * 2004-07-08 2006-01-26 Dr. Reddy's Laboratories Ltd. Polymorphic form of naratriptan hydrochloride
EP1781360A1 (de) 2004-08-12 2007-05-09 Alexza Pharmaceuticals, Inc. Aerosol-arzneiabgabevorrichtung mit perkussiv aktivierten wärmepackungen
US20080193518A1 (en) * 2006-04-28 2008-08-14 Schering Corporation Process for the precipitation and isolation of 6,6-Dimethyl-3-Aza Bicyclo [3.1.0] Hexane-Amide compounds by controlled precipitation and pharmaceutical formulations containing same
US8420122B2 (en) 2006-04-28 2013-04-16 Merck Sharp & Dohme Corp. Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same
JP2010500356A (ja) * 2006-08-09 2010-01-07 グラクソ グループ リミテッド ラクトースの製造方法
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
GB0705159D0 (en) 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) * 2007-06-18 2007-07-25 Prosonix Ltd Process
GB2487868B (en) * 2010-01-15 2014-12-10 Neothetics Inc Lyophilized cake formulations
AU2012282936B2 (en) * 2011-07-08 2016-11-10 Pfizer Limited Process for the preparation of fluticasone propionate form 1
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
EP2847207B1 (de) 2012-05-08 2019-03-27 Nicox Ophthalmics, Inc. Nanokristalle von Fluticasonpropionat
EP2705838A1 (de) * 2012-09-06 2014-03-12 Xspray Microparticles Ab Tiotropium-Zubereitungen
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
JP2018126699A (ja) * 2017-02-09 2018-08-16 水ｉｎｇ株式会社 晶析方法及び晶析装置
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3154395A (en) * 1961-01-30 1964-10-27 Universal Oil Prod Co Continuous fractional crystallization process
US3984409A (en) * 1973-08-09 1976-10-05 Pfizer Inc. Cyclic n-substituted derivatives of 1,4-benzene disulphonamide
NL7501406A (en) * 1975-02-06 1976-08-10 Dso Pharmachim Crystallisation of tetracycline hydrochloride - accelerated by subjecting to high-frequency vibrations, with purer, less toxic prod. formed
ES2078447T3 (es) * 1990-06-15 1995-12-16 Merck & Co Inc Un procedimiento de cristalizacion para mejorar la estructura y el tamaño de los cristales.
GB9313650D0 (en) * 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
BR9811437A (pt) * 1997-09-03 2000-08-22 Merck & Co Inc Processo para aumentar a pureza óptica do r-amino álcool
KR20010033747A (ko) * 1997-12-29 2001-04-25 태듀스 피. 프러스 Ｎ-Ｈｅｔ-치환 글리세로포스포에탄올아민
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
US6566516B1 (en) * 1998-08-31 2003-05-20 Nof Corporation High purity polysaccharide containing a hydrophobic group and process for producing it
SE9802974D0 (sv) * 1998-09-03 1998-09-03 Astra Ab New crystalline forms
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
TR200101891T2 (tr) * 1999-01-29 2001-12-21 Bristol-Myers Squibb Company Sonik etkili jet kristalleşme aparat ve cihazı.

Also Published As

Publication number Publication date
ES2260236T3 (es) 2006-11-01
JP2004500983A (ja) 2004-01-15
DE60118558T2 (de) 2006-08-24
US20030181432A1 (en) 2003-09-25
WO2002000198A1 (en) 2002-01-03
GB0015981D0 (en) 2000-08-23
EP1294359A1 (de) 2003-03-26
DE60118558D1 (de) 2006-05-18
EP1294359B1 (de) 2006-04-05
AU2001266218A1 (en) 2002-01-08

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