ATE323724T1 - Mpl-liganden analoga - Google Patents

Mpl-liganden analoga

Info

Publication number
ATE323724T1
ATE323724T1 AT96906617T AT96906617T ATE323724T1 AT E323724 T1 ATE323724 T1 AT E323724T1 AT 96906617 T AT96906617 T AT 96906617T AT 96906617 T AT96906617 T AT 96906617T AT E323724 T1 ATE323724 T1 AT E323724T1
Authority
AT
Austria
Prior art keywords
mpl ligand
analogs
ligand analogue
mpl
amino acids
Prior art date
Application number
AT96906617T
Other languages
English (en)
Inventor
Steven G Elliott
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/388,779 external-priority patent/US5696250A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE323724T1 publication Critical patent/ATE323724T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
AT96906617T 1995-02-15 1996-02-13 Mpl-liganden analoga ATE323724T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/388,779 US5696250A (en) 1995-02-15 1995-02-15 DNA encoding megakaryocyte growth and development factor analogs
US08/591,070 US5756083A (en) 1995-02-15 1996-02-09 Mpl ligand analogs

Publications (1)

Publication Number Publication Date
ATE323724T1 true ATE323724T1 (de) 2006-05-15

Family

ID=27012437

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96906617T ATE323724T1 (de) 1995-02-15 1996-02-13 Mpl-liganden analoga

Country Status (10)

Country Link
EP (1) EP0811064B1 (de)
JP (1) JP3836877B2 (de)
CN (1) CN1161468C (de)
AT (1) ATE323724T1 (de)
AU (1) AU691410B2 (de)
CA (1) CA2209298C (de)
DE (1) DE69636052T2 (de)
MX (1) MX9705943A (de)
NZ (1) NZ303588A (de)
WO (1) WO1996025498A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8192955B1 (en) 1994-01-03 2012-06-05 Genentech, Inc. Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
US8241900B1 (en) 1994-01-03 2012-08-14 Genentech, Inc. mpl ligand
US8357513B1 (en) 1994-01-03 2013-01-22 Genentech, Inc. Nucleic acids encoding mpl ligand (thrombopoietin) and fragments thereof
US5989538A (en) * 1995-02-15 1999-11-23 Amgen Inc. Mpl ligand analogs
PT1538202E (pt) * 1996-09-13 2014-04-22 Shire Human Genetic Therapies Produção de alga-galactosidase a humana
JP2001501619A (ja) * 1996-10-04 2001-02-06 アムジェン インコーポレーテッド ｍｐｌリガンドを含有する医薬組成物
US20030228666A1 (en) 1998-06-30 2003-12-11 Daewoong Pharmaceutical Co., Ltd. Novel human thrombopoietin mutein
KR20000006549A (ko) * 1998-06-30 2000-01-25 윤재승 생체내혈소판증식효능이향상된신규한트롬보포이에틴유도체
EP1216037A2 (de) 1999-09-21 2002-06-26 Emory University Verfahren und zusammensetzungen zur behandlung von bluttplätchen-zusammenhängenden krankheiten, mit mpl hemmenden agenten
AU2003271194A1 (en) * 2003-10-09 2005-04-21 Daewoong Co., Ltd. Process for purifying human thrombopoietin with high content of sialic acid
KR101040396B1 (ko) 2009-01-20 2011-06-09 한올바이오파마주식회사 변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법
WO2013130604A1 (en) * 2012-02-27 2013-09-06 Biogen Idec Ma Inc. High-throughput method for sialic acid quantitation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19500030A1 (de) * 1994-01-03 1995-07-06 Genentech Inc Thrombopoietin
SG47030A1 (en) * 1994-01-03 1998-03-20 Genentech Inc Thrombopoietin
EP0668352A1 (de) * 1994-02-14 1995-08-23 Kirin Brewery Company, Ltd. Protein mit TPO-Aktivität
DE69503849T2 (de) * 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
AU4163196A (en) * 1994-11-30 1996-06-19 Zymogenetics Inc. Low molecular weight thrombopoietin
US6254870B1 (en) * 1995-02-03 2001-07-03 G. D. Searle & Co. Thrombopoietin: IL-3 fusion protein

Also Published As

Publication number Publication date
EP0811064A2 (de) 1997-12-10
JP3836877B2 (ja) 2006-10-25
DE69636052T2 (de) 2007-04-12
MX9705943A (es) 1997-10-31
CA2209298A1 (en) 1996-08-22
HK1009151A1 (en) 1999-09-10
WO1996025498A3 (en) 1997-03-20
CA2209298C (en) 2001-12-18
CN1182453A (zh) 1998-05-20
DE69636052D1 (de) 2006-05-24
HK1005807A1 (en) 1999-01-29
AU691410B2 (en) 1998-05-14
NZ303588A (en) 1999-02-25
AU4994696A (en) 1996-09-04
CN1161468C (zh) 2004-08-11
WO1996025498A2 (en) 1996-08-22
JPH11500904A (ja) 1999-01-26
EP0811064B1 (de) 2006-04-19

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties