ATE325575T1 - Optischer sensor zur in-situ messung von analyten - Google Patents

Optischer sensor zur in-situ messung von analyten

Info

Publication number
ATE325575T1
ATE325575T1 AT01982427T AT01982427T ATE325575T1 AT E325575 T1 ATE325575 T1 AT E325575T1 AT 01982427 T AT01982427 T AT 01982427T AT 01982427 T AT01982427 T AT 01982427T AT E325575 T1 ATE325575 T1 AT E325575T1
Authority
AT
Austria
Prior art keywords
sensor
skin
analytes
optical sensor
situ measurement
Prior art date
Application number
AT01982427T
Other languages
English (en)
Inventor
Bo Petersson
Anders Weber
Original Assignee
Precisense As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precisense As filed Critical Precisense As
Application granted granted Critical
Publication of ATE325575T1 publication Critical patent/ATE325575T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685—Microneedles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT01982427T 2000-10-13 2001-10-12 Optischer sensor zur in-situ messung von analyten ATE325575T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0025147.0A GB0025147D0 (en) 2000-10-13 2000-10-13 Optical sensor for in situ measurement of analytes

Publications (1)

Publication Number Publication Date
ATE325575T1 true ATE325575T1 (de) 2006-06-15

Family

ID=9901242

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01982427T ATE325575T1 (de) 2000-10-13 2001-10-12 Optischer sensor zur in-situ messung von analyten

Country Status (15)

Country Link
US (1) US6671527B2 (de)
EP (1) EP1324691B1 (de)
JP (1) JP3873023B2 (de)
AT (1) ATE325575T1 (de)
AU (2) AU1401602A (de)
CA (1) CA2425337C (de)
CY (1) CY1105129T1 (de)
DE (1) DE60119556T2 (de)
DK (1) DK1324691T3 (de)
ES (1) ES2263671T3 (de)
GB (1) GB0025147D0 (de)
NO (1) NO334509B1 (de)
NZ (1) NZ525567A (de)
PT (1) PT1324691E (de)
WO (1) WO2002030275A1 (de)

Families Citing this family (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
CN100385232C (zh) 1998-08-26 2008-04-30 医药及科学传感器公司 基于光学的感测装置
US7553280B2 (en) 2000-06-29 2009-06-30 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
MXPA03010064A (es) * 2001-05-04 2004-03-09 Sensors For Med & Science Inc Dispositivo de deteccion electro-optico con canal de referencia.
AU2002312521A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
ATE497731T1 (de) 2001-06-12 2011-02-15 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
ES2336081T3 (es) 2001-06-12 2010-04-08 Pelikan Technologies Inc. Dispositivo de puncion de auto-optimizacion con medios de adaptacion a variaciones temporales en las propiedades cutaneas.
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
CA2448681C (en) 2001-06-12 2014-09-09 Pelikan Technologies, Inc. Integrated blood sampling analysis system with multi-use sampling module
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP1469903A2 (de) * 2001-09-28 2004-10-27 BioValve Technologies, Inc. Mikronadel mit membran
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
GB0204640D0 (en) 2002-02-27 2002-04-10 Torsana Diabetes Diagnostics A Injection apparatus
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7244265B2 (en) 2002-04-19 2007-07-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
EP1501402A4 (de) 2002-04-19 2008-07-02 Pelikan Technologies Inc Vorrichtung und verfahren für eine lanzette mit variabler geschwindigkeit
US7485128B2 (en) 2002-04-19 2009-02-03 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7481776B2 (en) 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
CA2509382A1 (en) * 2002-12-17 2004-07-08 Todd C. Zion Stimuli-responsive systems for controlled drug delivery
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
CN1806475B (zh) * 2003-04-15 2013-07-03 医药及科学传感器公司 具有集成天线的印刷电路装置和具有集成印刷电路板天线的可植入传感器处理系统
US7473548B2 (en) 2003-04-25 2009-01-06 Medtronic, Inc. Optical detector for enzyme activation
EP1628567B1 (de) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Verfahren und vorrichtung zur injektion von flüssigkeit
EP1633235B1 (de) 2003-06-06 2014-05-21 Sanofi-Aventis Deutschland GmbH Gerät für die entnahme von körperflüssigkeiten und analyten-nachweis
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7604592B2 (en) 2003-06-13 2009-10-20 Pelikan Technologies, Inc. Method and apparatus for a point of care device
US7632234B2 (en) * 2003-08-29 2009-12-15 Medtronic, Inc. Implantable biosensor devices for monitoring cardiac marker molecules
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US7496392B2 (en) 2003-11-26 2009-02-24 Becton, Dickinson And Company Fiber optic device for sensing analytes
US7787923B2 (en) * 2003-11-26 2010-08-31 Becton, Dickinson And Company Fiber optic device for sensing analytes and method of making same
GB0329161D0 (en) 2003-12-16 2004-01-21 Precisense As Reagant for detecting an analyte
GB0329849D0 (en) 2003-12-23 2004-01-28 Precisense As Fluorometers
EP1706026B1 (de) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
GB0411162D0 (en) * 2004-05-19 2004-06-23 Precisense As Optical sensor for in vivo detection of analyte
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
JP5502279B2 (ja) * 2004-10-28 2014-05-28 エコー セラピューティクス， インコーポレイテッド ヒドロゲルを使用した検体のサンプリングおよび分析のためのシステムおよび方法
GB0426822D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426823D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
DE502005005099D1 (de) * 2005-03-23 2008-10-02 Roche Diagnostics Gmbh Verfahren zur Bestimmung der Glucosekonzentration durch Fluoreszenzpolarisation
US7308292B2 (en) 2005-04-15 2007-12-11 Sensors For Medicine And Science, Inc. Optical-based sensing devices
US7704704B2 (en) * 2005-09-28 2010-04-27 The Texas A&M University System Implantable system for glucose monitoring using fluorescence quenching
US7687608B2 (en) 2005-10-19 2010-03-30 Smartcells, Inc. Methods for reducing the mitogenicity of lectin compositions
US20070173706A1 (en) * 2005-11-11 2007-07-26 Isense Corporation Method and apparatus for insertion of a sensor
US9615851B2 (en) 2005-11-11 2017-04-11 Waveform Technologies, Inc. Method and apparatus for insertion of a sensor
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US20100202966A1 (en) * 2006-03-28 2010-08-12 Yossi Gross Implantable Sensor
US7809441B2 (en) 2006-05-17 2010-10-05 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
WO2008042902A2 (en) 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US8560059B2 (en) * 2007-03-09 2013-10-15 Covidien Lp System and methods for optical sensing and drug delivery using microneedles
US7713196B2 (en) 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
WO2008131361A2 (en) * 2007-04-20 2008-10-30 Becton, Dickinson And Company Biosensors for measuring analytes in the interstitial fluid
GB0716159D0 (en) 2007-08-17 2007-09-26 Precisense As Injection apparatus
WO2009024521A2 (en) 2007-08-17 2009-02-26 Precisense A/S Injection apparatus for making an injection at a predetermined depth in the skin
CN100591388C (zh) * 2008-01-04 2010-02-24 南京大学 一种微针阵列注射器的制备方法
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
EP2174586B1 (de) * 2008-10-02 2014-12-10 EyeSense AG Implantierbares Sensorelement
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9517023B2 (en) 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
JP2011001469A (ja) * 2009-06-18 2011-01-06 Terumo Corp 蛍光ハイドロゲルビーズの製造方法
JP5380174B2 (ja) * 2009-06-18 2014-01-08 テルモ株式会社 蛍光ハイドロゲルビーズおよびそれを用いた体内埋め込み用の糖類測定用センサー
US10376213B2 (en) 2009-06-30 2019-08-13 Waveform Technologies, Inc. System, method and apparatus for sensor insertion
JP2013508119A (ja) 2009-10-26 2013-03-07 エムキネティクス， インコーポレイテッド 神経、筋肉および身体組織の電磁刺激のための方法および装置
JP2013519483A (ja) * 2010-02-19 2013-05-30 ライトシップ メディカル リミテッド 皮下グルコースセンサ
US8795595B2 (en) 2010-04-07 2014-08-05 Medtronic Minimed, Inc. Sensor substrate systems and methods
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP5214036B2 (ja) 2010-04-20 2013-06-19 パナソニック株式会社 生体に含有される生体成分の濃度を測定する方法
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
CN101905856B (zh) * 2010-06-11 2012-10-10 北京大学 一种用于透皮给药的平面空心微针的制备方法
WO2012046423A1 (ja) 2010-10-06 2012-04-12 パナソニック株式会社 生体に含有される生体成分の濃度を測定する方法
WO2012048150A1 (en) 2010-10-06 2012-04-12 Profusa, Inc. Tissue-integrating sensors
US8509868B2 (en) 2011-04-12 2013-08-13 Panasonic Corporation Method for measuring a concentration of a biogenic substance contained in a living body
US9642568B2 (en) 2011-09-06 2017-05-09 Medtronic Minimed, Inc. Orthogonally redundant sensor systems and methods
US8999720B2 (en) 2011-11-17 2015-04-07 Medtronic Minimed, Inc. Aqueous radiation protecting formulations and methods for making and using them
WO2014115516A1 (ja) 2013-01-25 2014-07-31 パナソニック株式会社 生体内における被検物質の濃度を計測する計測方法、および、計測装置
EP2970318B1 (de) 2013-03-14 2018-11-21 Profusa, Inc. Sauerstoffsensoren mit einem polymer und einem lumineszenzfarbstoff
WO2014158988A1 (en) 2013-03-14 2014-10-02 Profusa, Inc. Method and device for correcting optical signals
WO2014185067A1 (ja) 2013-05-17 2014-11-20 パナソニックＩｐマネジメント株式会社 センサ埋込装置およびセンサ埋込システム
US10219729B2 (en) 2013-06-06 2019-03-05 Profusa, Inc. Apparatus and methods for detecting optical signals from implanted sensors
US9636034B2 (en) 2013-10-23 2017-05-02 Verily Life Sciences Llc Non-invasive analyte detection system with modulation source
US10542918B2 (en) 2013-10-23 2020-01-28 Verily Life Sciences Llc Modulation of a response signal to distinguish between analyte and background signals
US9936905B2 (en) 2013-10-25 2018-04-10 Medtronic Minimed, Inc. Sensor with optical interface
AU2015264090A1 (en) * 2014-05-21 2016-12-15 Invention Development Management Company, Llc Tattoo and tattoo applicator for animal lifecycle monitoring
US9910035B1 (en) 2014-07-16 2018-03-06 Verily Life Sciences Llc Polyvalent functionalized nanoparticle-based in vivo diagnostic system
US9820690B1 (en) 2014-07-16 2017-11-21 Verily Life Sciences Llc Analyte detection system
US9874554B1 (en) 2014-07-16 2018-01-23 Verily Life Sciences Llc Aptamer-based in vivo diagnostic system
EP3206567A1 (de) 2014-10-13 2017-08-23 Glusense, Ltd. Analytmessvorrichtung
US20160354500A1 (en) 2015-06-02 2016-12-08 Medtronic Minimed, Inc. Protective agents against e-beam irradiation for proteins in optical sensing chemistry
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
EP3445872A1 (de) 2016-04-20 2019-02-27 Glusense Ltd. Fret-basierte glucosedetektionsmoleküle
CN110352036B (zh) 2016-12-21 2022-11-15 普罗菲尤萨股份有限公司 可聚合的近红外染料
WO2018119400A1 (en) 2016-12-22 2018-06-28 Profusa, Inc. System and single-channel luminescent sensor for and method of determining analyte value
US10543288B2 (en) 2017-04-28 2020-01-28 Medtronic Minimed, Inc. Modified-dextrans for use in optical glucose assays
US10792378B2 (en) 2017-04-28 2020-10-06 Medtronics Minimed, Inc. Using a blue-shifted reference dye in an optical glucose assay
CN108968976B (zh) 2017-05-31 2022-09-13 心脏起搏器股份公司 具有化学传感器的植入式医疗设备
WO2019023093A1 (en) 2017-07-26 2019-01-31 Cardiac Pacemakers, Inc. SYSTEMS AND METHODS FOR POSTURE DISAMBIGULATION
CN109381195B (zh) 2017-08-10 2023-01-10 心脏起搏器股份公司 包括电解质传感器融合的系统和方法
CN109419515B (zh) 2017-08-23 2023-03-24 心脏起搏器股份公司 具有分级激活的可植入化学传感器
CN109864746B (zh) 2017-12-01 2023-09-29 心脏起搏器股份公司 用于医学装置的多模式分析物传感器
CN109864747B (zh) 2017-12-05 2023-08-25 心脏起搏器股份公司 多模式分析物传感器光电子接口
WO2019142913A1 (ja) * 2018-01-18 2019-07-25 国立大学法人東京大学 ３次元組織内のグルコース濃度マッピングのための蛍光マイクロ粒子
KR20210040953A (ko) 2018-06-27 2021-04-14 프로퓨사 인코퍼레이티드 근적외선 글루코스 센서
TWI723731B (zh) * 2019-08-02 2021-04-01 華廣生技股份有限公司 生物感測器之植入裝置及其植入方法
US12551145B2 (en) 2020-10-29 2026-02-17 Cardiac Pacemakers, Inc. Integrated thermo-photonic chemical sensor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
DE2655801C2 (de) * 1976-12-09 1986-06-26 Kernforschungsanlage Jülich GmbH, 5170 Jülich Injizierbare Suspension von Membranvesikeln aus Erythrozyten und Verfahren zur Herstellung der Suspension
US4344438A (en) 1978-08-02 1982-08-17 The United States Of America As Represented By The Department Of Health, Education And Welfare Optical sensor of plasma constituents
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5101814A (en) * 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US6040194A (en) * 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
US5149655A (en) 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
TW360548B (en) 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
ATE278801T1 (de) 1995-11-22 2004-10-15 Medtronic Minimed Inc Detektion von biologischen molekülen unter verwendung von chemischer amplifikation und optischem sensor
GB9605690D0 (en) 1996-03-19 1996-05-22 Oxford Biosciences Ltd Particle delivery
US6232130B1 (en) * 1997-06-04 2001-05-15 Sensor Technologies, Inc. Method for detecting or quantifying carbohydrate containing compounds
EP1086214B1 (de) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Mikronadel-einrichtungen und verfahren zur deren herstellung
GB9814506D0 (en) 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
JP2002532165A (ja) 1998-12-18 2002-10-02 メドトロニック ミニメド インコーポレイテッド 医療装置と共に使われる、微小突刺し部材を備える挿入セット及びそのような挿入セットの使用方法

Also Published As

Publication number Publication date
WO2002030275A1 (en) 2002-04-18
NO20031685D0 (no) 2003-04-11
DK1324691T3 (da) 2006-09-11
JP3873023B2 (ja) 2007-01-24
DE60119556D1 (de) 2006-06-14
CA2425337A1 (en) 2002-04-18
JP2004510527A (ja) 2004-04-08
CA2425337C (en) 2012-01-10
DE60119556T2 (de) 2007-01-25
AU1401602A (en) 2002-04-22
EP1324691A1 (de) 2003-07-09
CY1105129T1 (el) 2010-03-03
GB0025147D0 (en) 2000-11-29
US20020058863A1 (en) 2002-05-16
NO20031685L (no) 2003-05-28
ES2263671T3 (es) 2006-12-16
NZ525567A (en) 2004-05-28
PT1324691E (pt) 2006-08-31
NO334509B1 (no) 2014-03-24
EP1324691B1 (de) 2006-05-10
AU2002214016B2 (en) 2005-06-16
US6671527B2 (en) 2003-12-30

Similar Documents

Publication Publication Date Title
ATE325575T1 (de) Optischer sensor zur in-situ messung von analyten
DE50013029D1 (de) Probenkammer zur Flüssigkeitsbehandlung biologischer Proben
GB2350421B (en) Apparatus and method of testing a biological fluid
GB9914238D0 (en) Electrochemical sensor for analysis of liquid samples
DE60026688D1 (de) Vorrichtung zur fokussierter probennahme von formations flüssigkeit.
DE60020565D1 (de) Leuchtende glukoseüberwachungsvorrichtung
DE69731000D1 (de) Vorrichtung zur messung von blut-parametern
AR012351A1 (es) Un metodo y dispositivos para dividir muestras biologicas liquidas en microvolumenes
ATE442579T1 (de) Verfahren und vorrichtung zur lumineszenzmessung
DE69927157D1 (de) Biologisch abbaubarer optischer Sensor zur in situ Messung von Analyten
WO2003100469A3 (en) Internal biochemical sensing device
DE69934219D1 (de) Vorrichtung zur blutanalyse
BR9814386B1 (pt) aparelhos e métodos para determinar a concentração de um componente medicamente significante de um fluido biológico.
EP1269917A4 (de) Gerät und verfahren zur messung von biologischen informationen
DE69808071D1 (de) Nachweistest unter benutzung von magnetteilchen
ATE373829T1 (de) Lipidassay-verfahren und reagenz zur verwendung darin
EA200100544A1 (ru) Способ экспресс-диагностики физиологического состояния биологического объекта и устройство для его осуществления
ATA5052000A (de) Vorrichtung zur aeroben fermentation von biologischen substanzen
AU2001276346A1 (en) Refractometric method for carrying out long-term stable accurate measurement of the concentrations of dissolved substances and miniaturizable device for carrying out said method
MX2007003245A (es) Tira de prueba biologica.
RU97100364A (ru) Способ для обнаружения и оценки концентрации анаэробных бактерий в биологическом субстрате
ATE483734T1 (de) Vorrichtung und verfahren zur bestimmung des eintretens und vorhandenseins septischer bedingungen
PT1043582E (pt) Camada sensora para controlo de difusao
WO2021124605A1 (ja) 生体試料保持容器及び生体試料保持方法

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1324691

Country of ref document: EP

REN Ceased due to non-payment of the annual fee