ATE326467T1 - Imidazo 1,2-aöpyridine - Google Patents

Imidazo 1,2-aöpyridine

Info

Publication number: ATE326467T1
Authority: AT; Austria
Prior art keywords: aöpyridine; imidazo
Prior art date: 2002-07-31

Application number

AT03766355T

Other languages

English (en)

Inventor

Nerina Dodic

Francoise J Gellibert

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-31

Filing date

2003-07-29

Publication date

2006-06-15

2003-07-29 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2006-06-15 Application granted granted Critical

2006-06-15 Publication of ATE326467T1 publication Critical patent/ATE326467T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Physical Education & Sports Medicine (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Addiction (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Surgery (AREA)
Immunology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT03766355T 2002-07-31 2003-07-29 Imidazo 1,2-aöpyridine ATE326467T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0217783.0A GB0217783D0 (en)	2002-07-31	2002-07-31	Compounds

Publications (1)

Publication Number	Publication Date
ATE326467T1 true ATE326467T1 (de)	2006-06-15

Family

ID=9941484

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03766355T ATE326467T1 (de)	2002-07-31	2003-07-29	Imidazo 1,2-aöpyridine

Country Status (11)

Country	Link
US (1)	US20050234029A1 (de)
EP (1)	EP1543003B1 (de)
JP (1)	JP2005537291A (de)
AR (1)	AR040724A1 (de)
AT (1)	ATE326467T1 (de)
AU (1)	AU2003255323A1 (de)
DE (1)	DE60305332T2 (de)
ES (1)	ES2259419T3 (de)
GB (1)	GB0217783D0 (de)
TW (1)	TW200413366A (de)
WO (1)	WO2004013138A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR039241A1 (es)	2002-04-04	2005-02-16	Biogen Inc	Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos
AU2003260345A1 (en) *	2002-07-31	2004-02-23	Smithkline Beecham Corporation	2-phenylpyridin-4-yl derivatives as alk5 inhibitors
UA80296C2 (en) *	2002-09-06	2007-09-10	Biogen Inc	Imidazolopyridines and methods of making and using the same
PA8595001A1 (es) *	2003-03-04	2004-09-28	Pfizer Prod Inc	Nuevos compuestos heteroaromaticos condensados que son inhibidores del factor de crecimiento transforante (tgf)
CN101277949A (zh)	2005-04-22	2008-10-01	阿兰托斯制药控股公司	二肽基肽酶-ⅳ抑制剂
WO2007028051A2 (en) *	2005-09-02	2007-03-08	Abbott Laboratories	Novel imidazo based heterocycles
WO2008082490A2 (en) *	2006-12-20	2008-07-10	Schering Corporation	Novel jnk inhibitors
CA2672940A1 (en)	2006-12-20	2008-07-10	Schering Corporation	Novel jnk inhibitors
MX2010004244A (es)	2007-10-17	2010-04-30	Novartis Ag	Derivados de imidazo [i,2-a]-piridina utiles como inhibidores de cinasa tipo activina (alk).
BRPI0822237A2 (pt) *	2007-12-21	2015-06-30	Wyeth Llc	Compostos de imidazo [1,2-a] piridina
CN102015691B (zh) *	2008-04-29	2014-01-08	诺华股份有限公司	作为活化素样受体激酶(alk4或alk5)抑制剂的咪唑并吡啶衍生物
CA2778949C (en)	2009-10-30	2018-02-27	Janssen Pharmaceutica Nv	Imidazo[1,2-b]pyridazine derivatives and their use as pde10 inhibitors
ES2574253T3 (es) *	2009-12-18	2016-06-16	Mitsubishi Tanabe Pharma Corporation	Nuevo agente antiplaquetario
AR080754A1 (es)	2010-03-09	2012-05-09	Janssen Pharmaceutica Nv	Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
WO2011146287A1 (en)	2010-05-20	2011-11-24	Takeda Pharmaceutical Company Limited	Pyrazolo[4,3-b]pyridine-7-amine inhibitors of alk5
US20120309796A1 (en)	2011-06-06	2012-12-06	Fariborz Firooznia	Benzocycloheptene acetic acids
BR112013033375B1 (pt)	2011-06-27	2022-05-10	Janssen Pharmaceutica N.V	Derivados de 1-aril-4-metil-[1,2,4]triazolo[4,3-a]quinoxa-lina, seu uso, composição farmacêutica que os compreende, processo de preparação dos mesmos, solução estéril e composto intermediário
RU2657540C2 (ru)	2012-06-26	2018-06-14	Янссен Фармацевтика Нв	Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств
EP2869822B1 (de)	2012-07-09	2016-09-14	Janssen Pharmaceutica, N.V.	Hemmer des phosphodiesterase-10-enzyms
CN108341769A (zh) *	2018-05-13	2018-07-31	浙江凯普化工有限公司	多取代的6-氟皮考啉酸的制备方法
CN115975224B (zh) *	2023-03-16	2023-08-08	四川大学	一种pH/ROS双响应的组织粘附载药水凝胶及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH11302177A (ja) *	1998-04-27	1999-11-02	Otsuka Pharmaceut Factory Inc	腎炎治療剤
GB0007405D0 (en) *	2000-03-27	2000-05-17	Smithkline Beecham Corp	Compounds
PE20020506A1 (es) *	2000-08-22	2002-07-09	Glaxo Group Ltd	Derivados de pirazol fusionados como inhibidores de la proteina cinasa
GB0027987D0 (en) *	2000-11-16	2001-01-03	Smithkline Beecham Plc	Compounds
US20040039198A1 (en) *	2000-11-16	2004-02-26	Bender Paul E.	Compounds
GB0100762D0 (en) *	2001-01-11	2001-02-21	Smithkline Beecham Plc	Novel use
AU2003260345A1 (en) *	2002-07-31	2004-02-23	Smithkline Beecham Corporation	2-phenylpyridin-4-yl derivatives as alk5 inhibitors

2002
- 2002-07-31 GB GBGB0217783.0A patent/GB0217783D0/en not_active Ceased
2003
- 2003-07-29 AT AT03766355T patent/ATE326467T1/de not_active IP Right Cessation
- 2003-07-29 DE DE60305332T patent/DE60305332T2/de not_active Expired - Fee Related
- 2003-07-29 ES ES03766355T patent/ES2259419T3/es not_active Expired - Lifetime
- 2003-07-29 EP EP03766355A patent/EP1543003B1/de not_active Expired - Lifetime
- 2003-07-29 TW TW092120589A patent/TW200413366A/zh unknown
- 2003-07-29 WO PCT/EP2003/008390 patent/WO2004013138A2/en not_active Ceased
- 2003-07-29 US US10/522,967 patent/US20050234029A1/en not_active Abandoned
- 2003-07-29 JP JP2004525375A patent/JP2005537291A/ja active Pending
- 2003-07-29 AR AR20030102720A patent/AR040724A1/es not_active Application Discontinuation
- 2003-07-29 AU AU2003255323A patent/AU2003255323A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2259419T3 (es)	2006-10-01
US20050234029A1 (en)	2005-10-20
AU2003255323A8 (en)	2004-02-23
JP2005537291A (ja)	2005-12-08
DE60305332D1 (de)	2006-06-22
EP1543003A2 (de)	2005-06-22
AR040724A1 (es)	2005-04-20
DE60305332T2 (de)	2007-04-19
TW200413366A (en)	2004-08-01
WO2004013138A3 (en)	2004-03-25
WO2004013138A2 (en)	2004-02-12
EP1543003B1 (de)	2006-05-17
GB0217783D0 (en)	2002-09-11
AU2003255323A1 (en)	2004-02-23

Legal Events

Date	Code	Title	Description
2006-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
CY2014041I1 (el)	2016-07-27	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
DE60216115D1 (de)	2006-12-28	BENZIMIDAZO 4,5-föISOCHINOLINON-DERIVATE
DK2308855T3 (da)	2013-01-28	2,4-Diaminopyrimidinderivater
BR0313875B1 (pt)	2013-01-22	escova de dentes.
BR0313318B1 (pt)	2013-02-19	escova de dentes.
NO20053248D0 (no)	2005-07-01	Kerosenblanding.
DE602004021572D1 (de)	2009-07-30	SUBSTITUIERTE 8-PERFLUORO-6,7,8,9-TETRAHYDROPYRIMIDOi1,2-A PYRIMIDIN-4-ON-DERIVATE
DE60305332D1 (de)	2006-06-22	IMIDAZOi1,2-AöPYRIDINE
NO20052248D0 (no)	2005-05-09	Svivelstykkesystem.
DK1487778T3 (da)	2012-08-06	Substituerede 4 aminocyclohexanoler
NO20051500D0 (no)	2005-03-21	Substituerte heterocyklylpyrimidiner.
ITMI20032170A1 (it)	2004-06-22	Tagliacimosse.
ITMI20022179A1 (it)	2004-04-16	Il manopoliero
NO20051497D0 (no)	2005-03-21	Beta-laktamaseinhibitorprodrug.
NO20044405L (no)	2004-10-15	Neurotensinaktive 2,3-diaryl-pyrazolidin derivater
ITMI20030916A1 (it)	2003-11-23	Lancetta.
ES1051942Y (es)	2003-02-16	Canape modular.
ES1052590Y (es)	2003-05-01	Quiosco-consigna.
ITRA20020023A1 (it)	2004-05-30	Il mollino.
FI20020644A0 (fi)	2002-04-04	Kompleksiliuos
DOP2002000452A (es)	2002-10-30	Pct 2002
ES1050939Y (es)	2002-10-01	Celosia antivandalica.
ES1051110Y (es)	2002-10-16	Caja-palet.
ES1052654Y (es)	2003-05-01	Cubitera.
ES1052011Y (es)	2003-03-01	Espetero.