ATE327258T1 - Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung - Google Patents

Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung

Info

Publication number
ATE327258T1
ATE327258T1 AT96906907T AT96906907T ATE327258T1 AT E327258 T1 ATE327258 T1 AT E327258T1 AT 96906907 T AT96906907 T AT 96906907T AT 96906907 T AT96906907 T AT 96906907T AT E327258 T1 ATE327258 T1 AT E327258T1
Authority
AT
Austria
Prior art keywords
monoclonal antibody
producing
reacting specifically
antibody reacting
fas ligand
Prior art date
Application number
AT96906907T
Other languages
English (en)
Inventor
Nobuhiko Kayagaki
Hideo Yagita
Ko Okumura
Motomi Nakata
Original Assignee
Ko Okumura
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ko Okumura filed Critical Ko Okumura
Application granted granted Critical
Publication of ATE327258T1 publication Critical patent/ATE327258T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT96906907T 1995-03-20 1996-03-21 Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung ATE327258T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8742095 1995-03-20
JP30349295 1995-10-27

Publications (1)

Publication Number Publication Date
ATE327258T1 true ATE327258T1 (de) 2006-06-15

Family

ID=26428696

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96906907T ATE327258T1 (de) 1995-03-20 1996-03-21 Monoklonaler antikörper, der spezifisch mit dem fas-liganden reagiert, und verfahren zu seiner herstellung

Country Status (8)

Country Link
US (1) US6946255B1 (de)
EP (1) EP0872488B1 (de)
JP (1) JP3451092B2 (de)
AT (1) ATE327258T1 (de)
AU (1) AU716731B2 (de)
CA (1) CA2215905A1 (de)
DE (1) DE69636170T2 (de)
WO (1) WO1996029350A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096312A (en) * 1995-06-30 2000-08-01 Mochida Pharmaceutical Co., Ltd. Agent for suppressing a reduction of CD4+ lymphocytes
CN1196733A (zh) * 1995-06-30 1998-10-21 持田制药株式会社 抗Fas配体抗体和利用抗Fas配体抗体的测定方法
US6114507A (en) * 1995-06-30 2000-09-05 Mochida Pharmaceutical Co., Ltd. Anti-Fas ligand antibody and assay method using the anti-Fas ligand antibody
JPH09124509A (ja) * 1995-10-27 1997-05-13 Sumitomo Electric Ind Ltd 肝炎治療剤
AU725329B2 (en) * 1996-09-02 2000-10-12 Ko Okumura Humanized immunoglobulin reacting specifically with Fas ligand or active fragments thereof and region inducing apoptosis originating in Fas ligand
WO2000029447A1 (en) * 1998-11-19 2000-05-25 Smithkline Beecham Corporation Rhamm antagonist antibodies
JP5253325B2 (ja) * 2002-09-04 2013-07-31 中外製薬株式会社 ＭＲＬ／ｌｐｒマウスを用いた抗体の作製
WO2004022595A1 (ja) * 2002-09-04 2004-03-18 Chugai Seiyaku Kabushiki Kaisha MRL/lprマウスを用いた抗体の作製
DK3517151T3 (da) 2006-03-09 2021-07-12 Aethlon Medical Inc Ekstrakorporal fjernelse af mikrovesikulære partikler
SI2428252T1 (sl) 2006-12-28 2015-01-30 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Nevtralizacija invazije aktivnostnih blokov cd95 v celicah glioblastoma in vivo
JP2011506371A (ja) * 2007-12-12 2011-03-03 ピンチェル ソチエタ・レスポンサビリタ・リミタータ 抗Ｆａｓリガンド抗体を含有する天疱瘡の治療薬
WO2010006772A2 (en) * 2008-07-14 2010-01-21 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Use of cd95 inhibitors for the treatment of inflammatory disorders
EP2166358A1 (de) * 2008-09-17 2010-03-24 Fundacio Institut de Recerca de l'Hospital Universitari Vall d'Hebron Differentialdiagnostisches Biomarker von einen Schlaganfall imitierenden Bedingungen und Verfahren zur Verwendung dieser
RU2556818C2 (ru) 2008-12-12 2015-07-20 Пинчел Срл СРЕДСТВА ДЛЯ ЛЕЧЕНИЯ ПУЗЫРЧАТКИ, СОДЕРЖАЩИЕ АНТИТЕЛА ПРОТИВ ЛИГАНДА Fas
EP3076179A1 (de) 2015-03-30 2016-10-05 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Diagnose und behandlung von minderwertigen glioma
CN108290950B (zh) * 2015-09-23 2022-01-28 阿珀吉科吉尼科斯股份公司 抗cd95l抗体
CN113402601A (zh) * 2021-06-09 2021-09-17 河南中泽生物工程有限公司 一种抗非洲猪瘟病毒p54蛋白单克隆抗体的制备方法及应用
US20250002596A1 (en) 2021-12-01 2025-01-02 Institut National de la Santé et de la Recherche Médicale Neutralizing anti-cd95l monoclonal antibodies
EP4514388A1 (de) 2022-04-26 2025-03-05 F. Hoffmann-La Roche AG Kombinationstherapie zur behandlung von krebs mit einem fas-achsen-antagonisten und einem t-reg-zelldepletionsmittel-antagonisten

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950588A (en) * 1985-07-10 1990-08-21 Molecular Diagnostics, Inc. Prolonged enhanced chemiluminescence
JPH08127594A (ja) * 1993-11-10 1996-05-21 Mochida Pharmaceut Co Ltd Ｆａｓ抗原に結合する新規蛋白質およびそれをコードするＤＮＡ
ATE387458T1 (de) * 1994-01-07 2008-03-15 Mochida Pharm Co Ltd Fas-antigenbindender ligand
DE4447484C2 (de) 1994-04-08 1997-07-17 Deutsches Krebsforsch Mittel zur Hemmung von Apoptose

Also Published As

Publication number Publication date
DE69636170D1 (de) 2006-06-29
WO1996029350A1 (en) 1996-09-26
AU716731B2 (en) 2000-03-02
EP0872488B1 (de) 2006-05-24
AU5014196A (en) 1996-10-08
EP0872488A1 (de) 1998-10-21
CA2215905A1 (en) 1996-09-26
JP3451092B2 (ja) 2003-09-29
EP0872488A4 (de) 1999-05-19
DE69636170T2 (de) 2006-11-02
US6946255B1 (en) 2005-09-20

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