ATE327749T1 - Hypoestoxide, derivate und agonisten davon zur verwendung bei der behandlung und prophylaxe von hyperlipidämie - Google Patents

Hypoestoxide, derivate und agonisten davon zur verwendung bei der behandlung und prophylaxe von hyperlipidämie

Info

Publication number: ATE327749T1
Authority: AT; Austria
Prior art keywords: prophylaxis; treatment; hypoestoxides; hyperlipidemia; agonists
Prior art date: 2002-10-28

Application number

AT03777932T

Other languages

English (en)

Inventor

Emeka J Nchekwube

Emmanuel A Ojo-Amaize

Howard B Cottam

Original Assignee

Paraquest Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-28

Filing date

2003-10-28

Publication date

2006-06-15

2003-10-28 Application filed by Paraquest Inc filed Critical Paraquest Inc

2006-06-15 Application granted granted Critical

2006-06-15 Publication of ATE327749T1 publication Critical patent/ATE327749T1/de

Links

208000031226 Hyperlipidaemia Diseases 0.000 title abstract 2
238000011321 prophylaxis Methods 0.000 title abstract 2
238000011282 treatment Methods 0.000 title abstract 2
239000000556 agonist Substances 0.000 title 1
238000000034 method Methods 0.000 abstract 2
208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
229930004069 diterpene Natural products 0.000 abstract 1
-1 diterpene compound Chemical class 0.000 abstract 1
208000006575 hypertriglyceridemia Diseases 0.000 abstract 1
HNPAHGHFONBTLV-KSJQNFQUSA-N hypoestoxide Chemical compound CC(=O)O[C@@H]1C[C@]2(C)O[C@H]2CC[C@]2(C)O[C@H]2C[C@@H]2CC(=O)C(=C)[C@@H]1C2(C)C HNPAHGHFONBTLV-KSJQNFQUSA-N 0.000 abstract 1
HNPAHGHFONBTLV-UHFFFAOYSA-N hypoestoxide Natural products CC(=O)OC1CC2(C)OC2CCC2(C)OC2CC2CC(=O)C(=C)C1C2(C)C HNPAHGHFONBTLV-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT03777932T 2002-10-28 2003-10-28 Hypoestoxide, derivate und agonisten davon zur verwendung bei der behandlung und prophylaxe von hyperlipidämie ATE327749T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US42153302P	2002-10-28	2002-10-28

Publications (1)

Publication Number	Publication Date
ATE327749T1 true ATE327749T1 (de)	2006-06-15

Family

ID=32230237

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03777932T ATE327749T1 (de)	2002-10-28	2003-10-28	Hypoestoxide, derivate und agonisten davon zur verwendung bei der behandlung und prophylaxe von hyperlipidämie

Country Status (9)

Country	Link
US (1)	US20040087553A1 (de)
EP (1)	EP1558240B1 (de)
CN (1)	CN1731992A (de)
AT (1)	ATE327749T1 (de)
AU (1)	AU2003286721A1 (de)
BR (1)	BR0306632A (de)
CA (1)	CA2509834A1 (de)
DE (1)	DE60305727T2 (de)
WO (1)	WO2004039362A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7229979B2 (en) *	2003-06-23	2007-06-12	Immune Modulation, Inc.	Hypoestoxides, derivatives and agonists thereof for use as stent-coating agents
US20060094695A1 (en) *	2004-11-02	2006-05-04	Paraquest, Inc.	Hypoestoxides, derivatives and agonists thereof for use in the prophylaxis and treatment of obesity
HK1249044A1 (zh) *	2015-03-09	2018-10-26	Immune Modulation, Inc.	用於治疗或预防神经退行性疾病的枪刀药素氧化物、其衍生物、相关化合物和激动剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4938949A (en) *	1988-09-12	1990-07-03	University Of New York	Treatment of damaged bone marrow and dosage units therefor
US5801193A (en) *	1997-04-15	1998-09-01	Immune Modulation, Inc.	Compositions and methods for immunosuppressing
US5994328A (en) *	1998-01-14	1999-11-30	Immune Modulation, Inc.	Hypoestoxides, derivatives and agonists thereof for use as anticancer agents
US6001871A (en) *	1998-01-15	1999-12-14	Immune Modulation, Inc.	Hypoestoxides, derivatives and agonists thereof for use as antiviral agents
US6242484B1 (en) *	1999-07-06	2001-06-05	Paraquest, Inc.	Hypoestoxides, derivatives and agonists thereof for use of antiparasitic agents

2003
- 2003-10-28 WO PCT/US2003/034157 patent/WO2004039362A2/en not_active Ceased
- 2003-10-28 BR BR0306632-0A patent/BR0306632A/pt not_active Application Discontinuation
- 2003-10-28 AU AU2003286721A patent/AU2003286721A1/en not_active Abandoned
- 2003-10-28 AT AT03777932T patent/ATE327749T1/de not_active IP Right Cessation
- 2003-10-28 CN CNA2003801078605A patent/CN1731992A/zh active Pending
- 2003-10-28 US US10/694,934 patent/US20040087553A1/en not_active Abandoned
- 2003-10-28 DE DE60305727T patent/DE60305727T2/de not_active Expired - Fee Related
- 2003-10-28 EP EP03777932A patent/EP1558240B1/de not_active Expired - Lifetime
- 2003-10-28 CA CA002509834A patent/CA2509834A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2003286721A1 (en)	2004-05-25
CN1731992A (zh)	2006-02-08
US20040087553A1 (en)	2004-05-06
WO2004039362A3 (en)	2004-07-08
EP1558240A2 (de)	2005-08-03
EP1558240B1 (de)	2006-05-31
DE60305727D1 (de)	2006-07-06
CA2509834A1 (en)	2004-05-13
DE60305727T2 (de)	2007-05-31
BR0306632A (pt)	2004-09-28
WO2004039362A2 (en)	2004-05-13

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Legal Events

Date	Code	Title	Description
2006-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties