ATE329910T1 - 5-trityloxymethyl-2-oxazolidinon und verfahren zu dessen herstellung - Google Patents
5-trityloxymethyl-2-oxazolidinon und verfahren zu dessen herstellungInfo
- Publication number
- ATE329910T1 ATE329910T1 AT01953494T AT01953494T ATE329910T1 AT E329910 T1 ATE329910 T1 AT E329910T1 AT 01953494 T AT01953494 T AT 01953494T AT 01953494 T AT01953494 T AT 01953494T AT E329910 T1 ATE329910 T1 AT E329910T1
- Authority
- AT
- Austria
- Prior art keywords
- trityloxymethyl
- oxazolidinone
- production
- trityloxy
- oxazolidinones
- Prior art date
Links
- NONOANCJDOAYFL-UHFFFAOYSA-N 5-(trityloxymethyl)-1,3-oxazolidin-2-one Chemical compound O1C(=O)NCC1COC(C=1C=CC=CC=1)(C=1C=CC=CC=1)C1=CC=CC=C1 NONOANCJDOAYFL-UHFFFAOYSA-N 0.000 title abstract 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical class O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 abstract 1
- TWONBQKNUBYLDQ-UHFFFAOYSA-N 3-hydroxy-4-trityloxybutanamide Chemical compound C=1C=CC=CC=1C(C=1C=CC=CC=1)(OCC(O)CC(=O)N)C1=CC=CC=C1 TWONBQKNUBYLDQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 230000003542 behavioural effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/665,508 US6288239B1 (en) | 2000-09-19 | 2000-09-19 | 5-trityloxymethyl-oxazolidinones and process for the preparation thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE329910T1 true ATE329910T1 (de) | 2006-07-15 |
Family
ID=24670388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01953494T ATE329910T1 (de) | 2000-09-19 | 2001-07-16 | 5-trityloxymethyl-2-oxazolidinon und verfahren zu dessen herstellung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6288239B1 (de) |
| EP (1) | EP1324989B1 (de) |
| JP (1) | JP3974035B2 (de) |
| KR (1) | KR100525882B1 (de) |
| AT (1) | ATE329910T1 (de) |
| AU (2) | AU2001275937B2 (de) |
| CA (1) | CA2418200C (de) |
| DE (1) | DE60120729D1 (de) |
| TW (1) | TWI237637B (de) |
| WO (1) | WO2002024670A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU230030B1 (hu) | 1999-10-08 | 2015-05-28 | Debiopharm International Sa | Fab I inhibitorok |
| EP1560584B1 (de) * | 2001-04-06 | 2009-01-14 | Affinium Pharmaceuticals, Inc. | Fab-i-inhibitoren |
| WO2003106413A2 (en) * | 2001-10-18 | 2003-12-24 | Michigan State University | Process for the preparation of oxazolidinones and method of use thereof |
| EP1575951B1 (de) * | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterozyclische verbindungen, verfahren zu deren herstellung und ihre verwendung als heilmittel |
| WO2004082586A2 (en) * | 2003-03-17 | 2004-09-30 | Affinium Pharmaceuticals, Inc. | Phamaceutical compositions comprising inhibitors of fab i and further antibiotics |
| DK1828167T3 (da) * | 2004-06-04 | 2014-10-20 | Debiopharm Int Sa | Acrylamidderivater som antibiotiske midler |
| KR20080075027A (ko) * | 2005-12-05 | 2008-08-13 | 아피늄 파마슈티컬스, 인크. | Fabi 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물 |
| JP5468899B2 (ja) | 2006-07-20 | 2014-04-09 | アフィニウム ファーマシューティカルズ, インク. | Fabiインヒビターとしてのアクリルアミド誘導体 |
| EP2125802A4 (de) | 2007-02-16 | 2014-08-20 | Debiopharm Int Sa | Salze, prodrugs und polymorphe von fab-i-inhibitoren |
| KR200453944Y1 (ko) * | 2011-03-08 | 2011-06-03 | 조명호 | 음식물 배달용기 |
| AU2013279021C1 (en) | 2012-06-19 | 2017-03-16 | Debiopharm International Sa | Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide |
| RS61312B1 (sr) | 2016-02-26 | 2021-02-26 | Debiopharm Int Sa | Lek za lečenje infekcija dijabetskog stopala |
| TN2021000159A1 (en) | 2019-02-14 | 2023-04-04 | Debiopharm Int Sa | Afabicin formulation, method for making the same and uses thereof |
| SG11202113174SA (en) | 2019-06-14 | 2021-12-30 | Debiopharm Int Sa | Medicament and use thereof for treating bacterial infections involving biofilm |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5122601A (en) * | 1990-12-07 | 1992-06-16 | Hawaiian Sugar Planters'association | Synthesis of 2,3,3',4,4'-penta-o-methylsucrose |
| CA2049536C (en) | 1991-05-13 | 1999-07-06 | Rawle I. Hollingsworth | Process for the preparation of 3,4-dihydroxybutanoic acid and salts thereof |
| DK1114819T3 (da) | 1996-04-11 | 2008-04-14 | Pharmacia & Upjohn Co Llc | Fremgangsmåde til fremstilling af oxazolidinoner |
| US5808107A (en) | 1997-10-31 | 1998-09-15 | Board Of Trustees Operating Michigan State University | Process for the preparation of hydroxy substituted gamma butyrolactones |
| IT1301977B1 (it) * | 1998-07-31 | 2000-07-20 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione di r-(-)-carnitina |
-
2000
- 2000-09-19 US US09/665,508 patent/US6288239B1/en not_active Expired - Fee Related
-
2001
- 2001-07-16 KR KR10-2003-7002770A patent/KR100525882B1/ko not_active Expired - Fee Related
- 2001-07-16 AU AU2001275937A patent/AU2001275937B2/en not_active Ceased
- 2001-07-16 DE DE60120729T patent/DE60120729D1/de not_active Expired - Fee Related
- 2001-07-16 CA CA002418200A patent/CA2418200C/en not_active Expired - Fee Related
- 2001-07-16 JP JP2002529080A patent/JP3974035B2/ja not_active Expired - Fee Related
- 2001-07-16 AT AT01953494T patent/ATE329910T1/de not_active IP Right Cessation
- 2001-07-16 EP EP01953494A patent/EP1324989B1/de not_active Expired - Lifetime
- 2001-07-16 AU AU7593701A patent/AU7593701A/xx active Pending
- 2001-07-16 WO PCT/US2001/022296 patent/WO2002024670A1/en not_active Ceased
- 2001-09-19 TW TW090122961A patent/TWI237637B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU7593701A (en) | 2002-04-02 |
| KR20030025301A (ko) | 2003-03-28 |
| EP1324989A1 (de) | 2003-07-09 |
| CA2418200C (en) | 2006-07-04 |
| KR100525882B1 (ko) | 2005-11-02 |
| EP1324989B1 (de) | 2006-06-14 |
| TWI237637B (en) | 2005-08-11 |
| JP3974035B2 (ja) | 2007-09-12 |
| AU2001275937B2 (en) | 2005-08-11 |
| DE60120729D1 (de) | 2006-07-27 |
| WO2002024670A1 (en) | 2002-03-28 |
| JP2004523473A (ja) | 2004-08-05 |
| CA2418200A1 (en) | 2002-03-28 |
| US6288239B1 (en) | 2001-09-11 |
| EP1324989A4 (de) | 2005-07-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |