ATE330002T1 - Verfahren zur herstellung von membranvesikeln - Google Patents
Verfahren zur herstellung von membranvesikelnInfo
- Publication number
- ATE330002T1 ATE330002T1 AT01943246T AT01943246T ATE330002T1 AT E330002 T1 ATE330002 T1 AT E330002T1 AT 01943246 T AT01943246 T AT 01943246T AT 01943246 T AT01943246 T AT 01943246T AT E330002 T1 ATE330002 T1 AT E330002T1
- Authority
- AT
- Austria
- Prior art keywords
- membrane vesicles
- preparations
- methods
- relates
- present
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 3
- 210000001808 exosome Anatomy 0.000 abstract 2
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000012620 biological material Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 238000011026 diafiltration Methods 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 238000003908 quality control method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
- C23C16/4401—Means for minimising impurities, e.g. dust, moisture or residual gas, in the reaction chamber
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
- C23C16/50—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
- C23C16/505—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges
- C23C16/509—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges using internal electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J37/00—Discharge tubes with provision for introducing objects or material to be exposed to the discharge, e.g. for the purpose of examination or processing thereof
- H01J37/32—Gas-filled discharge tubes
- H01J37/32431—Constructional details of the reactor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Metallurgy (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Plasma & Fusion (AREA)
- Cell Biology (AREA)
- Materials Engineering (AREA)
- Mechanical Engineering (AREA)
- Pulmonology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/561,205 US6812023B1 (en) | 2000-04-27 | 2000-04-27 | Methods of producing membrane vesicles |
| US09/780,748 US20040241176A1 (en) | 2000-04-27 | 2001-02-09 | Method of producing membrane vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE330002T1 true ATE330002T1 (de) | 2006-07-15 |
Family
ID=27072576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01943246T ATE330002T1 (de) | 2000-04-27 | 2001-04-11 | Verfahren zur herstellung von membranvesikeln |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040241176A1 (de) |
| EP (1) | EP1278825B1 (de) |
| JP (1) | JP2003531864A (de) |
| CN (1) | CN1426461A (de) |
| AT (1) | ATE330002T1 (de) |
| AU (1) | AU6587301A (de) |
| CA (1) | CA2407225A1 (de) |
| DE (1) | DE60120683D1 (de) |
| EA (1) | EA005425B1 (de) |
| IL (1) | IL152472A0 (de) |
| WO (1) | WO2001082958A2 (de) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE508363T1 (de) | 2000-12-06 | 2011-05-15 | Ecole Polytech | Verfahren zur herstellung eines bioanalytischen reagenzes, nachweisverfahren beruhend auf der verwendung des bioanalytischen reagenz, sowie dessen verwendung |
| IL160142A0 (en) | 2001-08-17 | 2004-06-20 | Anosys Inc | Methods and compounds for the targeting of protein to exosomes |
| US7771998B2 (en) | 2001-11-29 | 2010-08-10 | Dandrit Biotech A/S | Pharmaceutical composition for inducing an immune response in a human or animal |
| EP1483372A2 (de) * | 2002-03-14 | 2004-12-08 | Anosys, Inc. | Funktionalisierung von vesikeln, die von t zellen produziert wurden, und deren verwendung zur herstellung immunogener pharmazeutischer zusammensetzungen |
| KR20030085659A (ko) * | 2002-04-30 | 2003-11-07 | 동부한농화학 주식회사 | 암 치료용 엑소좀 및 그를 이용한 암 백신 |
| KR100519384B1 (ko) * | 2002-08-13 | 2005-10-06 | (주)누백스 | 유전자 이입을 이용한 엑소좀의 제조방법 및 상기 엑소좀의 용도 |
| JP4939926B2 (ja) * | 2003-02-14 | 2012-05-30 | アノシス・インコーポレーテッド | 抗体を生成し抗体レパートリーをスクリーニングするための方法とコンパウンド |
| FR2852393B1 (fr) * | 2003-03-14 | 2007-04-13 | Univ Aix Marseille Ii | Methode de detection et d'analyse d'organelle immobilises sur biopuce et leurs applications |
| GB0316560D0 (en) * | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| JP2008501336A (ja) * | 2004-06-02 | 2008-01-24 | ソースフアーム・インコーポレイテツド | Rnaを含有する微小胞およびそのための方法 |
| US7901921B2 (en) * | 2004-10-22 | 2011-03-08 | Oncolytics Biotech Inc. | Viral purification methods |
| CA2504279A1 (en) * | 2005-04-15 | 2006-10-15 | University Of Saskatchewan | Materials and method of modulating the immune response using t helper-antigen presenting cells |
| WO2006116362A2 (en) | 2005-04-25 | 2006-11-02 | The Trustees Of Boston University | Structured substrates for optical surface profiling |
| CN101641010A (zh) * | 2007-01-26 | 2010-02-03 | 路易斯维尔大学研究基金会公司 | 用作疫苗的外来体组分的修饰 |
| US20100255514A1 (en) | 2007-08-16 | 2010-10-07 | The Royal Institution For The Advancement Of Learning/Mcgill University | Tumor cell-derived microvesicles |
| CA2733672C (en) | 2007-08-16 | 2018-09-11 | The Royal Institution For The Advancement Of Learning/Mcgill University | Tumor cell-derived microvesicles |
| US8617806B2 (en) * | 2008-01-25 | 2013-12-31 | Hansabiomed Ou | Method to measure and characterize microvesicles in the human body fluids |
| WO2011009104A1 (en) * | 2009-07-16 | 2011-01-20 | The General Hospital Corporation | Nucleic acid analysis |
| US9487837B2 (en) | 2008-10-06 | 2016-11-08 | Morehouse School Of Medicine | Exosome-mediated diagnosis of hepatitis virus infections and diseases |
| US10545149B2 (en) * | 2008-10-06 | 2020-01-28 | Morehouse School Of Medicine | Detection of HIV-related proteins in urine |
| US7888035B2 (en) | 2008-10-30 | 2011-02-15 | Caris Mpi, Inc. | Methods for assessing RNA patterns |
| WO2010056337A2 (en) | 2008-11-12 | 2010-05-20 | Caris Mpi, Inc. | Methods and systems of using exosomes for determining phenotypes |
| WO2010065968A1 (en) * | 2008-12-05 | 2010-06-10 | Myriad Genetics, Inc. | Cancer detection markers |
| US9835618B1 (en) * | 2009-02-06 | 2017-12-05 | Los Alamos National Security, Llc | Discovery, detection and use of biomarkers |
| US20130053426A1 (en) | 2009-04-17 | 2013-02-28 | Yiqi Seow | Composition For Delivery Of Genetic Material |
| CN102596177B (zh) | 2009-07-01 | 2014-05-28 | 阿昂梅迪克斯公司 | 来源于有核哺乳动物细胞的微囊泡及其应用 |
| KR20120081972A (ko) | 2009-07-02 | 2012-07-20 | 아이티에이치 임뮨 세라피 홀딩스 에이비 | 엑소좀에 기초한 암의 치료 |
| EP2475988B1 (de) | 2009-09-09 | 2018-11-14 | The General Hospital Corporation | Verwendung von mikrovesikeln bei der analyse von nukleinsäureprofilen |
| US20130029339A1 (en) | 2009-09-09 | 2013-01-31 | The General Hospital Corporation | Use of microvesicles in analyzing kras mutations |
| EP2542696B1 (de) | 2010-03-01 | 2016-09-28 | Caris Life Sciences Switzerland Holdings GmbH | Theranostik-biomarker |
| JP2013526852A (ja) | 2010-04-06 | 2013-06-27 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | 疾患に対する循環バイオマーカー |
| EP2578236B1 (de) | 2010-05-26 | 2016-03-30 | Micromedmark Biotech Co., Ltd | Herstellung von mikrovesikel-si-rna-komplexen und ihre verwendung bei der behandlung von aids |
| US9376679B2 (en) | 2010-05-26 | 2016-06-28 | Micromedmark Biotech Co. Ltd. | Microvesicles carrying small interfering RNAs, preparation methods and uses thereof |
| WO2012031008A2 (en) | 2010-08-31 | 2012-03-08 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| CA2817111C (en) | 2010-11-10 | 2019-03-05 | Exosome Diagnostics, Inc. | Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom |
| SG183579A1 (en) * | 2011-02-11 | 2012-09-27 | Agency Science Tech & Res | Methods of detecting therapeutic exosomes |
| ITNA20110012A1 (it) * | 2011-03-14 | 2012-09-15 | Amal Raj Delfin Albert | Procedura di isolamento e di purificazione degli esosomi urinari per la ricerca di biomarcatori proteici |
| RU2014115999A (ru) * | 2011-09-22 | 2015-10-27 | Универсидад Де Лос Андес | Способ мониторинга, диагностики и/или прогнозирования острого повреждения почек на ранней стадии |
| GB201121070D0 (en) * | 2011-12-07 | 2012-01-18 | Isis Innovation | composition for delivery of biotherapeutics |
| WO2013109713A1 (en) | 2012-01-18 | 2013-07-25 | The General Hospital Corporation | Targeting rnas to microvesicles |
| CN103479682B (zh) * | 2012-06-14 | 2015-03-11 | 苏州恒宇生物科技有限公司 | 一种植物来源活性成分-纳米级膜性囊泡的制备方法 |
| JP2015524849A (ja) | 2012-08-15 | 2015-08-27 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | 神経変性疾患に対するエキソソームに基づく治療法 |
| US20140186293A1 (en) * | 2012-12-31 | 2014-07-03 | University Of Louisville Research Foundation, Inc. | Immunoglobulin-bound extracellular vesicles and uses thereof |
| CA2910802A1 (en) | 2013-04-12 | 2014-10-16 | Samir El Andaloussi | Therapeutic delivery vesicles |
| CN104274828B (zh) * | 2013-07-04 | 2017-11-17 | 复旦大学 | IFN‑α处理细胞所分泌外体在制备抑制肝炎病毒的药物中的应用 |
| JP6547625B2 (ja) | 2013-10-25 | 2019-07-24 | 凸版印刷株式会社 | 膜小胞回収デバイス、膜小胞回収方法、及び膜小胞分析方法 |
| CN106573220B (zh) | 2014-07-24 | 2019-08-16 | 凸版印刷株式会社 | 脂质膜结构体、脂质膜结构体固定化载体、及胞体的融合方法 |
| US10329323B2 (en) | 2014-07-25 | 2019-06-25 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Method for purifying antibodies using PBS |
| AU2016327573B2 (en) | 2015-09-22 | 2022-07-14 | Trustees Of Boston University | Multiplexed phenotyping of nanovesicles |
| CA3001065A1 (en) * | 2015-10-14 | 2017-04-20 | Xiaoxi WEI | Compositions and methods for reducing ice crystal formation |
| WO2017136676A1 (en) | 2016-02-05 | 2017-08-10 | Nanoview Diagnostics Inc. | Detection of exosomes having surface markers |
| EP3467059B1 (de) | 2016-05-24 | 2022-02-23 | Japanese Foundation For Cancer Research | Verfahren zur rückgewinnung von extrazellulären vesikeln und behälter für extrazelluläre vesikel |
| GB2552473A (en) * | 2016-07-21 | 2018-01-31 | Evox Therapeutics Ltd | Surface decoration of extracellular vesicles |
| WO2018071681A1 (en) * | 2016-10-13 | 2018-04-19 | Vbc Holdings Llc | Cancer stem cell exosomes |
| US11493412B2 (en) | 2016-11-23 | 2022-11-08 | Aman Sharma | Method and kit for exosomes and associated biomacromolecules capture |
| CN107907689A (zh) * | 2017-10-10 | 2018-04-13 | 北京大学 | 外泌体蛋白cd5l的检测方法 |
| NL2019814B1 (en) * | 2017-10-26 | 2019-05-06 | Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis | Methods for producing a MHC multimer. |
| JP7337438B2 (ja) | 2018-03-30 | 2023-09-04 | エクソソミクス・ソシエタ・ペル・アチオニ | 血球および血小板由来の細胞外小胞を困窮化させた血液または血液誘導体を得るための中空糸の使用 |
| WO2019232321A1 (en) | 2018-06-01 | 2019-12-05 | NanoView Biosciences, Inc. | Compositions, systems, and methods for enhanced label-free and fluorescence - based detection of nanoparticles |
| JP7376887B2 (ja) * | 2019-08-20 | 2023-11-09 | Jfeエンジニアリング株式会社 | 動物細胞の増殖促進方法、連続培養方法及び連続培養装置 |
| JP7513869B2 (ja) * | 2020-03-23 | 2024-07-10 | 澁谷工業株式会社 | エクソソーム抽出装置およびエクソソームの抽出方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2766205B1 (fr) * | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| FR2785543B1 (fr) * | 1998-11-05 | 2003-02-28 | Inst Nat Sante Rech Med | Exosomes modifies et utilisations |
-
2001
- 2001-02-09 US US09/780,748 patent/US20040241176A1/en not_active Abandoned
- 2001-04-11 WO PCT/EP2001/004173 patent/WO2001082958A2/en not_active Ceased
- 2001-04-11 CA CA002407225A patent/CA2407225A1/en not_active Abandoned
- 2001-04-11 EP EP01943246A patent/EP1278825B1/de not_active Expired - Lifetime
- 2001-04-11 DE DE60120683T patent/DE60120683D1/de not_active Expired - Lifetime
- 2001-04-11 JP JP2001579831A patent/JP2003531864A/ja active Pending
- 2001-04-11 CN CN01808615A patent/CN1426461A/zh active Pending
- 2001-04-11 AU AU65873/01A patent/AU6587301A/en not_active Abandoned
- 2001-04-11 AT AT01943246T patent/ATE330002T1/de not_active IP Right Cessation
- 2001-04-11 EA EA200201150A patent/EA005425B1/ru not_active IP Right Cessation
- 2001-04-11 IL IL15247201A patent/IL152472A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60120683D1 (de) | 2006-07-27 |
| EP1278825A2 (de) | 2003-01-29 |
| JP2003531864A (ja) | 2003-10-28 |
| EA005425B1 (ru) | 2005-02-24 |
| WO2001082958A2 (en) | 2001-11-08 |
| CN1426461A (zh) | 2003-06-25 |
| US20040241176A1 (en) | 2004-12-02 |
| WO2001082958A3 (en) | 2002-04-18 |
| AU6587301A (en) | 2001-11-12 |
| EP1278825B1 (de) | 2006-06-14 |
| CA2407225A1 (en) | 2001-11-08 |
| IL152472A0 (en) | 2003-05-29 |
| EA200201150A1 (ru) | 2003-04-24 |
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