ATE330011T1 - Bevorzugte segmente des ntp-proteins (neural thread protein) und verfahren zu deren verwendung - Google Patents

Bevorzugte segmente des ntp-proteins (neural thread protein) und verfahren zu deren verwendung

Info

Publication number
ATE330011T1
ATE330011T1 AT01988772T AT01988772T ATE330011T1 AT E330011 T1 ATE330011 T1 AT E330011T1 AT 01988772 T AT01988772 T AT 01988772T AT 01988772 T AT01988772 T AT 01988772T AT E330011 T1 ATE330011 T1 AT E330011T1
Authority
AT
Austria
Prior art keywords
protein
preferred
segments
neural thread
ntp
Prior art date
Application number
AT01988772T
Other languages
English (en)
Inventor
Judith Fitzpatrick
Paul Averback
Ma Soledad S Focht
Riza Bibiano
Original Assignee
Nymox Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nymox Pharmaceutical Corp filed Critical Nymox Pharmaceutical Corp
Application granted granted Critical
Publication of ATE330011T1 publication Critical patent/ATE330011T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT01988772T 2000-10-27 2001-10-25 Bevorzugte segmente des ntp-proteins (neural thread protein) und verfahren zu deren verwendung ATE330011T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/697,590 US7259232B1 (en) 2000-10-27 2000-10-27 Preferred segments of neural thread protein

Publications (1)

Publication Number Publication Date
ATE330011T1 true ATE330011T1 (de) 2006-07-15

Family

ID=24801714

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01988772T ATE330011T1 (de) 2000-10-27 2001-10-25 Bevorzugte segmente des ntp-proteins (neural thread protein) und verfahren zu deren verwendung

Country Status (15)

Country Link
US (2) US7259232B1 (de)
EP (2) EP1379650B1 (de)
JP (1) JP2005512500A (de)
KR (1) KR100843792B1 (de)
CN (1) CN1492926A (de)
AT (1) ATE330011T1 (de)
AU (1) AU2002232392A1 (de)
BR (1) BR0114977A (de)
CA (1) CA2427070A1 (de)
CY (1) CY1105380T1 (de)
DE (1) DE60120782T2 (de)
DK (1) DK1379650T3 (de)
ES (1) ES2266296T3 (de)
PT (1) PT1379650E (de)
WO (1) WO2002034915A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002302239B2 (en) * 2000-10-27 2006-12-14 Nymox Corporation Method of preventing cell death using segments of neural thread proteins
EP1541166B1 (de) * 2001-05-16 2007-12-19 Nymox Corporation Prävention des Zelltodes durch Verwendung von Segmenten der Neurofilamentproteinen
JP2004529179A (ja) 2001-05-16 2004-09-24 ナイモックス コーポレーション 神経線維タンパク質のセグメントを使用する細胞死の予防法
BR0209990A (pt) * 2001-05-25 2004-06-29 Nymox Corp Peptìdeos efetivos no tratamento de tumores e outras condições que requerem a remoção ou destruição de células
US7544771B2 (en) * 2005-02-23 2009-06-09 Nymox Corporation Protein and its use in diagnosing Alzheimer's disease
US11628202B2 (en) 2015-07-24 2023-04-18 Nymox Corporation Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia
US10183058B2 (en) 2016-06-17 2019-01-22 Nymox Corporation Method of preventing or reducing the progression of prostate cancer
US10172910B2 (en) 2016-07-28 2019-01-08 Nymox Corporation Method of preventing or reducing the incidence of acute urinary retention
US10532081B2 (en) 2016-09-07 2020-01-14 Nymox Corporation Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
US10335453B2 (en) 2017-03-01 2019-07-02 Nymox Corporation Compositions and methods for improving sexual function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068375A3 (de) 1981-06-22 1983-04-13 G.D. Searle & Co. Rekombinante DNS Technik zur Herstellung von Relaxin
SE8300693L (sv) 1983-02-09 1984-08-10 Sven Lofdahl Sett att framstella och isolera proteiner och polypeptider samt en hybridvektor for detta
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5084559A (en) 1987-03-27 1992-01-28 Repligen Corporation Protein a domain mutants
EP0378924B1 (de) 1988-12-21 1996-11-13 The General Hospital Corporation Nachweis einer neurologischen Krankheit oder einer Funktionsstörung
US5948634A (en) 1988-12-21 1999-09-07 The General Hospital Coporation Neural thread protein gene expression and detection of alzheimer's disease
EP0671470B9 (de) * 1994-03-07 2004-11-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung
GB9422175D0 (en) 1994-11-03 1994-12-21 Univ Dundee Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof
US5958416A (en) 1994-12-16 1999-09-28 Regents Of The University Of Minnesota Heat shock protein peptides and methods for modulating autoimmune central nervous system disease
US6610506B1 (en) * 1995-12-01 2003-08-26 University Technologies International, Inc. Transferrin binding proteins of Pasteurella haemolytica and vaccines containing same
US6013763A (en) 1996-06-04 2000-01-11 Genentech, Inc. Peptide variants of protein A
EP1030819A4 (de) 1997-09-30 2001-11-21 Cel Sci Corp Immunogene konjugierte polypeptide für die behandlung von herpes-simplex virus
WO2000001720A2 (en) 1998-07-02 2000-01-13 President And Fellows Of Harvard College Compositions and methods for treating papillomavirus-infected cells
AU3517000A (en) 1999-03-12 2000-10-04 Human Genome Sciences, Inc. 50 human secreted proteins
JP2002539842A (ja) 1999-03-26 2002-11-26 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ４５個のヒト分泌タンパク質
JP2004529179A (ja) 2001-05-16 2004-09-24 ナイモックス コーポレーション 神経線維タンパク質のセグメントを使用する細胞死の予防法

Also Published As

Publication number Publication date
AU2002232392A1 (en) 2002-05-06
DK1379650T3 (da) 2006-10-23
CA2427070A1 (en) 2002-05-02
US7259232B1 (en) 2007-08-21
EP1379650A2 (de) 2004-01-14
CY1105380T1 (el) 2010-04-28
EP1702985A2 (de) 2006-09-20
ES2266296T3 (es) 2007-03-01
EP1702985A3 (de) 2007-03-07
BR0114977A (pt) 2006-05-09
US20090258426A1 (en) 2009-10-15
WO2002034915A2 (en) 2002-05-02
DE60120782D1 (de) 2006-07-27
EP1379650B1 (de) 2006-06-14
WO2002034915A3 (en) 2003-11-20
KR20030067681A (ko) 2003-08-14
KR100843792B1 (ko) 2008-07-03
JP2005512500A (ja) 2005-05-12
CN1492926A (zh) 2004-04-28
PT1379650E (pt) 2006-10-31
DE60120782T2 (de) 2007-05-24

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