ATE331730T1 - Neue depsipeptid-verbindung - Google Patents

Neue depsipeptid-verbindung

Info

Publication number: ATE331730T1
Authority: AT; Austria
Prior art keywords: depsipeptide compound; new depsipeptide; new; activity; compound
Prior art date: 1999-01-13

Application number

AT00900351T

Other languages

English (en)

Inventor

Koji Nagai

Nakako Arao

Kinya Sohda

Kazuma Kamigiri

Masamichi Mori

Nobuaki Shindo

Haruo Seto

Kazuo Shin-Ya

Original Assignee

Astellas Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-13

Filing date

2000-01-12

Publication date

2006-07-15

2000-01-12 Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc

2006-07-15 Application granted granted Critical

2006-07-15 Publication of ATE331730T1 publication Critical patent/ATE331730T1/de

Links

-1 DEPSIPEPTIDE COMPOUND Chemical class 0.000 title 1
108010002156 Depsipeptides Proteins 0.000 title 1
206010028980 Neoplasm Diseases 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000001472 cytotoxic effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Crystallography & Structural Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT00900351T 1999-01-13 2000-01-12 Neue depsipeptid-verbindung ATE331730T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP704099		1999-01-13

Publications (1)

Publication Number	Publication Date
ATE331730T1 true ATE331730T1 (de)	2006-07-15

Family

ID=11654946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00900351T ATE331730T1 (de)	1999-01-13	2000-01-12	Neue depsipeptid-verbindung

Country Status (13)

Country	Link
US (2)	US6670326B1 (de)
EP (1)	EP1142905B1 (de)
JP (1)	JP3554707B2 (de)
KR (1)	KR100611265B1 (de)
CN (1)	CN1173990C (de)
AT (1)	ATE331730T1 (de)
AU (1)	AU2002700A (de)
CA (1)	CA2356845C (de)
DE (1)	DE60029084T2 (de)
DK (1)	DK1142905T3 (de)
ES (1)	ES2265906T3 (de)
PT (1)	PT1142905E (de)
WO (1)	WO2000042062A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1414971A (zh) *	1999-12-08	2003-04-30	埃克斯西特治疗公司	用作免疫抑制剂的缩肽及其同类物
US7098186B2 (en) *	2002-08-30	2006-08-29	Astellas Pharma Inc	Depsipeptide compound
EP1920779A4 (de) *	2005-08-12	2010-03-10	Astellas Pharma Inc	Technik zur stabilisierung der yw753-reparatur
US7943568B2 (en) *	2005-09-30	2011-05-17	The Ohio State University Research Foundation	Antitumor agents
CA2670223A1 (en) *	2006-11-22	2008-05-29	Karus Therapeutics Limited	Depsipeptides and their therapeutic use
GB0623357D0 (en) *	2006-11-22	2007-01-03	Karus Therapeutics Ltd	Chemical compounds
GB0623388D0 (en) *	2006-11-23	2007-01-03	Univ Southampton	Chemical compounds
GB0715750D0 (en) *	2007-08-13	2007-09-19	Karus Therapeutics Ltd	Chemical compounds
WO2014115859A2 (ja)	2013-01-25	2014-07-31	オンコリスバイオファーマ株式会社	分子標的併用腫瘍治療・予防薬
WO2018119142A1 (en)	2016-12-21	2018-06-28	Amgen Inc.	Anti-tnf alpha antibody formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61101501A (ja)	1984-10-24	1986-05-20	Yamanouchi Pharmaceut Co Ltd	制癌作用を有する多糖及びその製法
GB8817743D0 (en)	1988-07-26	1988-09-01	Fujisawa Pharmaceutical Co	Fr901228 substance & preparation thereof
US5681813A (en) *	1994-04-06	1997-10-28	Pharma Mar, S.A.	Thiodepsipeptide isolated from a marine actinomycete

2000
- 2000-01-12 DK DK00900351T patent/DK1142905T3/da active
- 2000-01-12 JP JP2000593629A patent/JP3554707B2/ja not_active Expired - Lifetime
- 2000-01-12 CA CA2356845A patent/CA2356845C/en not_active Expired - Lifetime
- 2000-01-12 US US09/889,303 patent/US6670326B1/en not_active Expired - Lifetime
- 2000-01-12 ES ES00900351T patent/ES2265906T3/es not_active Expired - Lifetime
- 2000-01-12 AT AT00900351T patent/ATE331730T1/de active
- 2000-01-12 PT PT00900351T patent/PT1142905E/pt unknown
- 2000-01-12 DE DE60029084T patent/DE60029084T2/de not_active Expired - Lifetime
- 2000-01-12 AU AU20027/00A patent/AU2002700A/en not_active Abandoned
- 2000-01-12 CN CNB00802510XA patent/CN1173990C/zh not_active Expired - Lifetime
- 2000-01-12 KR KR1020017008693A patent/KR100611265B1/ko not_active Expired - Lifetime
- 2000-01-12 EP EP00900351A patent/EP1142905B1/de not_active Expired - Lifetime
- 2000-01-12 WO PCT/JP2000/000110 patent/WO2000042062A1/ja not_active Ceased
2003
- 2003-10-15 US US10/684,656 patent/US7098024B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU2002700A (en)	2000-08-01
CN1173990C (zh)	2004-11-03
KR100611265B1 (ko)	2006-08-10
DE60029084T2 (de)	2007-02-01
CN1335852A (zh)	2002-02-13
PT1142905E (pt)	2006-10-31
US6670326B1 (en)	2003-12-30
EP1142905A4 (de)	2004-05-19
US20040082054A1 (en)	2004-04-29
CA2356845A1 (en)	2000-07-20
EP1142905B1 (de)	2006-06-28
KR20010101443A (ko)	2001-11-14
ES2265906T3 (es)	2007-03-01
DK1142905T3 (da)	2006-09-18
EP1142905A1 (de)	2001-10-10
WO2000042062A1 (en)	2000-07-20
US7098024B2 (en)	2006-08-29
JP3554707B2 (ja)	2004-08-18
CA2356845C (en)	2010-10-19
DE60029084D1 (de)	2006-08-10

Legal Events

Date

Code

Title

Description

2007-04-15

UEP

Publication of translation of european patent specification

Ref document number: 1142905

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