ATE331791T1 - Phosphodiesterase 10 - Google Patents

Phosphodiesterase 10

Info

Publication number
ATE331791T1
ATE331791T1 AT99934307T AT99934307T ATE331791T1 AT E331791 T1 ATE331791 T1 AT E331791T1 AT 99934307 T AT99934307 T AT 99934307T AT 99934307 T AT99934307 T AT 99934307T AT E331791 T1 ATE331791 T1 AT E331791T1
Authority
AT
Austria
Prior art keywords
polypeptides
pde10
polynucleotides
binding partners
expression constructs
Prior art date
Application number
AT99934307T
Other languages
English (en)
Inventor
Kate Loughney
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE331791T1 publication Critical patent/ATE331791T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cereal-Derived Products (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99934307T 1998-02-23 1999-02-23 Phosphodiesterase 10 ATE331791T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7550898P 1998-02-23 1998-02-23

Publications (1)

Publication Number Publication Date
ATE331791T1 true ATE331791T1 (de) 2006-07-15

Family

ID=22126229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99934307T ATE331791T1 (de) 1998-02-23 1999-02-23 Phosphodiesterase 10

Country Status (8)

Country Link
US (4) US6350603B1 (de)
EP (1) EP1060251B1 (de)
JP (1) JP2002504341A (de)
AT (1) ATE331791T1 (de)
AU (1) AU3307999A (de)
CA (1) CA2321224A1 (de)
DE (1) DE69932153T2 (de)
WO (1) WO1999042596A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001025444A2 (en) * 1999-10-07 2001-04-12 Zymogenetics, Inc. Novel human phosphodiesterase zcytor13
US20040152106A1 (en) * 1999-10-07 2004-08-05 Robertson Harold A. Gene necessary for striatal function, uses thereof, and compounds for modulating same
AU7766300A (en) * 1999-10-07 2001-05-10 Novaneuron Inc. Gene necessary for striatal function, uses thereof, and compounds for modulatingsame
AU2002312801A1 (en) * 2001-04-11 2002-10-28 Altana Pharma Ag Human phosphodiesterase 9a isoform
EP1666886A3 (de) * 2001-04-20 2006-06-21 Pfizer Products Inc. Verfahren zur Identifizierung eines selektiven PDE10 Hemmers
IL149106A0 (en) * 2001-04-20 2002-11-10 Pfizer Prod Inc Therapeutic use of selective pde10 inhibitors
EP1321034A1 (de) * 2001-12-21 2003-06-25 Pfizer Products Inc. Unterbrechung des Phosphodiesterase 10 Gens
WO2004044235A1 (en) * 2002-11-13 2004-05-27 Bayer Healthcare Ag DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN PHOSPHODIESTERASE 7A1 (PDE7a1)
AU2003294728A1 (en) * 2002-12-09 2004-06-30 Bayer Healthcare Ag DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN PHOSPHODIESTERASE 9a2 (PDE9a2)
WO2004053492A1 (en) * 2002-12-09 2004-06-24 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human phosphodiesterase 9a3 (pde9a3)
EP1608743A2 (de) * 2003-04-03 2005-12-28 Memory Pharmaceutical Corporation Phosphodiesterase-10a7-isoformen und verwendungsverfahren
KR20070116015A (ko) * 2005-02-28 2007-12-06 니코메드 게엠베하 Ｐｄｅ10 조절자의 식별 방법
US7446345B2 (en) * 2005-04-29 2008-11-04 Cree, Inc. Light emitting devices with active layers that extend into opened pits
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
US20090176829A1 (en) 2006-05-02 2009-07-09 Pfizer Inc Bicyclic heteroaryl compounds as pde10 inhibitors
US7786139B2 (en) 2006-11-21 2010-08-31 Omeros Corporation PDE10 inhibitors and related compositions and methods
WO2008079111A1 (en) * 2006-12-20 2008-07-03 Carrier Corporation Method for determining refrigerant charge
JP5580192B2 (ja) * 2007-03-27 2014-08-27 オメロス コーポレーション 運動障害の処置のためのｐｄｅ７インヒビターの使用
US8637528B2 (en) * 2007-03-27 2014-01-28 Omeros Corporation Use of PDE7 inhibitors for the treatment of movement disorders
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3027279A1 (de) * 1980-07-18 1982-05-06 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Substituierte adenosin-3',5'-phosphorsaeurebenzyltriester, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ES2151463T5 (es) 1989-12-22 2012-10-29 Merck Serono Sa Constructos de ADN para la activación y la modificación de la expresión de genes endógenos
ATE250629T1 (de) 1991-04-19 2003-10-15 Univ Washington Für säugetierphosphodiesterasen kodierende dns
AU664847B2 (en) 1991-05-15 1995-12-07 Cell Genesys, Inc. Genomic modifications with homologous DNA targeting
TW402639B (en) 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
ATE199569T1 (de) * 1993-05-27 2001-03-15 Univ Washington Cyclisch gmp bindende cyclisch gmp spezifische phosphodiesterase materialien und verfahren.
GB9518220D0 (en) 1995-09-06 1995-11-08 Medical Res Council Checkpoint gene
US5798246A (en) * 1996-03-25 1998-08-25 Incyte Pharmaceuticals, Inc. Cyclic nucleotide phosphodiesterase
US5922595A (en) 1997-12-09 1999-07-13 Incyte Pharmaceuticals, Inc. Cyclic GMP phosphodiesterase

Also Published As

Publication number Publication date
US6350603B1 (en) 2002-02-26
US20030148378A1 (en) 2003-08-07
AU3307999A (en) 1999-09-06
US20050009062A1 (en) 2005-01-13
WO1999042596A3 (en) 2000-03-02
WO1999042596A2 (en) 1999-08-26
US20030044950A1 (en) 2003-03-06
EP1060251A2 (de) 2000-12-20
US6864070B2 (en) 2005-03-08
DE69932153T2 (de) 2007-05-31
JP2002504341A (ja) 2002-02-12
DE69932153D1 (en) 2006-08-10
US6734003B2 (en) 2004-05-11
CA2321224A1 (en) 1999-08-26
EP1060251B1 (de) 2006-06-28

Similar Documents

Publication Publication Date Title
ATE331791T1 (de) Phosphodiesterase 10
NO992916L (no) Fosfodiesterase 8A
WO2001007628A3 (en) Human synthetases
WO1996034107A3 (en) Antiviral proteins, dna coding sequences therefor, and uses thereof
ZA987491B (en) Naphthyridinones for inhibiting protein tyrosine kinase and cell cycle kinase mediated cellular proliferation
CA2315274A1 (en) Polypeptides having aminopeptidase activity and nucleic acids encoding same
WO1998050424A3 (en) Human serine protease precursor
WO1999058692A3 (en) Human apoptosis associated proteins
AU7489098A (en) Polypeptides having aminopeptidase activity and nucleic acids encoding same
WO2000052151A3 (en) Human secretory proteins
WO2001007471A3 (en) Cell cycle and proliferation proteins
IL149416A0 (en) Human enzymes of the metalloprotease family
DK0935652T3 (da) Keratinocyt vækstfaktor-2 produkter
WO1999031128A3 (en) Human tumor necrosis factor-r2-like proteins
IL129139A0 (en) Vertebrate smoothened proteins
WO1999009182A3 (en) Rab proteins
WO2000023589A3 (en) Proliferation and apoptosis related proteins
WO2003070878A3 (en) Antisense modulation of hematopoietic cell protein tyrosine kinase expression
WO1999031225A3 (en) Human phosphatases
WO1999049037A3 (en) Protein phosphatase-related molecules
WO2000077179A3 (en) Human poly(adp-ribose) polymerase 2 materials and methods
AU7139501A (en) Control of metabolism with compositions of the human 2-oxoglutarate carrier
WO1999043829A3 (en) Cell cycle related proteins
WO2000071679A3 (en) Human oxidoreductase proteins
WO2000052161A3 (en) Leukocyte- and blood-associated proteins

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties