ATE333323T1 - Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung - Google Patents

Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung

Info

Publication number
ATE333323T1
ATE333323T1 AT04721159T AT04721159T ATE333323T1 AT E333323 T1 ATE333323 T1 AT E333323T1 AT 04721159 T AT04721159 T AT 04721159T AT 04721159 T AT04721159 T AT 04721159T AT E333323 T1 ATE333323 T1 AT E333323T1
Authority
AT
Austria
Prior art keywords
particles
liquid
liquid flow
compartment
deflection
Prior art date
Application number
AT04721159T
Other languages
English (en)
Inventor
Torsten Mueller
Thomas Schnelle
Rolf Hagedorn
Original Assignee
Evotec Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evotec Ag filed Critical Evotec Ag
Application granted granted Critical
Publication of ATE333323T1 publication Critical patent/ATE333323T1/de

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Electrostatic Separation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Cyclones (AREA)
AT04721159T 2003-03-17 2004-03-17 Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung ATE333323T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10311716A DE10311716A1 (de) 2003-03-17 2003-03-17 Verfahren und Vorrichtung zur Trennung von Partikeln in einer Flüssigkeitsströmung

Publications (1)

Publication Number Publication Date
ATE333323T1 true ATE333323T1 (de) 2006-08-15

Family

ID=32980607

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04721159T ATE333323T1 (de) 2003-03-17 2004-03-17 Verfahren und vorrichtung zur trennung von partikeln in einer flüssigkeitsströmung

Country Status (5)

Country Link
US (2) US8262883B2 (de)
EP (1) EP1603678B1 (de)
AT (1) ATE333323T1 (de)
DE (2) DE10311716A1 (de)
WO (1) WO2004082840A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9815058B2 (en) 2003-05-08 2017-11-14 The University Court Of The University Of St Andrews Fractionation of particles
US7704362B2 (en) * 2005-03-04 2010-04-27 Wisconsin Alumni Research Foundation Apparatus for transport and analysis of particles using dielectrophoresis
DE102005012128A1 (de) * 2005-03-16 2006-09-21 Evotec Technologies Gmbh Mikrofluidisches System und zugehöriges Ansteuerverfahren
DE102005046657B4 (de) * 2005-09-29 2008-10-09 Bruker Daltonik Gmbh Stationäres Trennsystem für Gemischkomponenten
US20070105206A1 (en) * 2005-10-19 2007-05-10 Chang Lu Fluidic device
CN100457239C (zh) * 2005-12-30 2009-02-04 财团法人工业技术研究院 多样品微流体介电泳分离装置
GB0618605D0 (en) * 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
GB0618606D0 (en) 2006-09-21 2006-11-01 Univ St Andrews Optical sorting
DE102006052925A1 (de) * 2006-11-09 2008-05-15 Evotec Technologies Gmbh Feldkäfig und zugehöriges Betriebsverfahren
US8698031B2 (en) * 2007-04-17 2014-04-15 Dynamic Connections, Llc Separation and manipulation of a chiral object
US7935906B2 (en) * 2007-04-17 2011-05-03 Dynamic Connections, Llc Separation and manipulation of a chiral object
US20090050482A1 (en) * 2007-08-20 2009-02-26 Olympus Corporation Cell separation device and cell separation method
US8740600B1 (en) * 2007-10-09 2014-06-03 Isopur Technologies, Inc. Apparatus for agglomerating particles in a non-conductive liquid
KR101338349B1 (ko) * 2007-11-30 2013-12-06 연세대학교 산학협력단 미세입자 분리 장치 및 이의 제작 방법
JP2011516867A (ja) * 2008-04-03 2011-05-26 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア 細胞、小胞、ナノ粒子およびバイオマーカーを分離および単離するためのエキソビボの多次元システム
KR101023040B1 (ko) * 2008-11-13 2011-03-24 한국항공대학교산학협력단 고속 입자분리 장치 및 그 방법
DE102011050254A1 (de) * 2011-05-10 2012-11-15 Technische Universität Dortmund Verfahren zur Separation polarisierbarer Biopartikel
CA2845713A1 (en) * 2011-08-19 2013-02-28 David Martin Morrow Gradient array dielectrophoresis separation (grads) with concomitant light therapy
SG11201400151RA (en) * 2011-09-07 2014-07-30 Panasonic Healthcare Co Ltd Microorganism quantity measurement cell and microorganism quantity measurement device comprising same
JP5924276B2 (ja) * 2012-04-03 2016-05-25 ソニー株式会社 流路デバイス、粒子分取装置及び粒子分取方法
US8932815B2 (en) 2012-04-16 2015-01-13 Biological Dynamics, Inc. Nucleic acid sample preparation
BR112014025695B1 (pt) 2012-04-16 2021-08-03 Biological Dynamics, Inc Preparação de amostra de ácido nucleico
US9192944B2 (en) * 2012-09-30 2015-11-24 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Methods, systems and apparatus for size-based particle separation
US9731293B2 (en) * 2012-10-03 2017-08-15 The United States Of America, As Represented By The Secretary Of The Navy Paired laser and electrokinetic separation, manipulation, and analysis device
JP6299749B2 (ja) * 2013-03-26 2018-03-28 ソニー株式会社 測定装置
KR101501983B1 (ko) * 2013-06-05 2015-03-13 한국항공대학교산학협력단 음의 유전 영동력 기반의 고효율 다단 세포 분리장치
EP3049531B8 (de) * 2013-09-24 2019-08-14 AIT Austrian Institute of Technology GmbH Verfahren zur pathogendiagnose mittels eines elektrischen feldes
EP4253937A3 (de) 2014-02-26 2023-11-08 Brigham and Women's Hospital, Inc. Verfahren zur zelllevetation und -überwachung
US20150273231A1 (en) * 2014-03-31 2015-10-01 Electronics And Telecommunications Research Institute Plasma system
JP2017512483A (ja) 2014-04-08 2017-05-25 バイオロジカル ダイナミクス，インク． 生体物質の単離のための改良された装置
US10657869B2 (en) 2014-09-10 2020-05-19 E Ink Corporation Methods for driving color electrophoretic displays
JP6272623B2 (ja) 2014-09-10 2018-01-31 イー インク コーポレイション 着色電気泳動ディスプレイ
US20160327549A1 (en) * 2015-05-04 2016-11-10 Biological Dynamics, Inc. Particle based immunoassay with alternating current electrokinetics
CN115487880A (zh) 2016-03-24 2022-12-20 生物动力学公司 一次性射流卡盘及组件
US10629833B2 (en) * 2016-11-21 2020-04-21 Northwestern University Flashing ratchets
CN106323727B (zh) * 2016-11-21 2023-07-14 大连海事大学 一种基于微通道内液体拉力效应的颗粒分离装置及方法
US10596567B2 (en) * 2017-03-27 2020-03-24 International Business Machines Corporation Microfluidic ratchets for displacing particles
EP3622084A4 (de) 2017-05-08 2021-02-17 Biological Dynamics, Inc. Verfahren und systeme zur verarbeitung von analytinformationen
CN107262288B (zh) * 2017-07-27 2023-03-21 重庆科技学院 带有金属颗粒的静电式净化装置
CN107442285B (zh) * 2017-07-27 2023-03-24 重庆科技学院 静电式滤清装置
US11731132B2 (en) 2017-12-19 2023-08-22 Biological Dynamics, Inc. Methods and devices for detection of multiple analytes from a biological sample
WO2019195196A1 (en) 2018-04-02 2019-10-10 Biological Dynamics, Inc. Dielectric materials
US12181448B2 (en) 2019-12-27 2024-12-31 Imec Vzw Method for continuously separating components from a sample
EP3842146B1 (de) * 2019-12-27 2025-01-29 Imec VZW Verfahren und vorrichtung zur kontinuierlichen trennung von komponenten aus einer probe
US11454583B2 (en) 2019-12-27 2022-09-27 Imec Vzw Field-array free flow fractionation
CN116157727B (zh) 2020-09-15 2026-07-31 伊英克公司 提供快速、高对比度的光学状态切换的四粒子电泳介质
US11846863B2 (en) 2020-09-15 2023-12-19 E Ink Corporation Coordinated top electrode—drive electrode voltages for switching optical state of electrophoretic displays using positive and negative voltages of different magnitudes
US12181767B2 (en) 2020-09-15 2024-12-31 E Ink Corporation Five-particle electrophoretic medium with improved black optical state
US11776496B2 (en) 2020-09-15 2023-10-03 E Ink Corporation Driving voltages for advanced color electrophoretic displays and displays with improved driving voltages
CN115400879B (zh) * 2022-08-26 2025-05-09 河南工业大学 一种微流控介电泳芯片及其制作方法和在液态金属微粒分选中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE339122B (de) * 1968-05-10 1971-09-27 Lkb Produkter Ab
DE4127405C2 (de) 1991-08-19 1996-02-29 Fraunhofer Ges Forschung Verfahren zur Trennung von Gemischen mikroskopisch kleiner, in einer Flüssigkeit oder einem Gel suspendierter dielektrischer Teilchen und Vorrichtung zur Durchführung des Verfahrens
DE19500683B4 (de) * 1994-12-10 2007-03-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Trapping von Molekülen und Mikropartikeln in Feldkäfigen
DE19540683A1 (de) 1995-11-01 1997-05-07 Behr Gmbh & Co Wärmeüberträger zum Kühlen von Abgas
US5993630A (en) * 1996-01-31 1999-11-30 Board Of Regents The University Of Texas System Method and apparatus for fractionation using conventional dielectrophoresis and field flow fractionation
EP0925494B1 (de) 1996-09-04 2001-12-19 Scandinavian Micro Biodevices A/S Mikrofliesssystem für die teilchenanalyse und trennung
WO2000000292A1 (de) 1998-06-26 2000-01-06 Evotec Biosystems Ag Elektrodenanordnung zur dielektrophoretischen partikelablenkung
JP2000061472A (ja) * 1998-08-18 2000-02-29 Kurita Water Ind Ltd 水中微粒子の除去方法および装置
DE19859459A1 (de) 1998-12-22 2000-06-29 Evotec Biosystems Ag Mikrosysteme zur Zellpermeation und Zellfusion
WO2000073780A1 (en) * 1999-05-28 2000-12-07 Proteologics, Inc. Methods and apparatus for nonlinear mobility electrophoresis separation
DE19952322C2 (de) 1999-10-29 2002-06-13 Evotec Ag Verfahren und Vorrichtung zur Partikeltrennung
DE60130052T2 (de) * 2000-04-13 2008-05-15 Wako Pure Chemical Industries, Ltd. Elektroden-Bau für dielektrophoretische Anordnung und dielektrophoretische Trennung
JP2004503775A (ja) * 2000-06-14 2004-02-05 ボード・オブ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム 検体混合物の組み合わせた磁気泳動および誘電泳動の操作のための方法および装置
US20020121443A1 (en) * 2000-11-13 2002-09-05 Genoptix Methods for the combined electrical and optical identification, characterization and/or sorting of particles
DE10136275C1 (de) 2001-07-25 2002-12-12 Fraunhofer Ges Forschung Verfahren und Vorrichtung zur Probentrennung
US6783647B2 (en) * 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
US7156970B2 (en) * 2003-06-12 2007-01-02 Palo Alto Research Center Incorporated Distributed multi-segmented reconfigurable traveling wave grids for separation of proteins in gel electrophoresis
EP1951742A4 (de) * 2005-10-27 2011-06-01 Life Technologies Corp Optoelektronische trennung von biomolekülen

Also Published As

Publication number Publication date
EP1603678A1 (de) 2005-12-14
US9149813B2 (en) 2015-10-06
DE10311716A1 (de) 2004-10-14
WO2004082840A1 (de) 2004-09-30
US20060289341A1 (en) 2006-12-28
US20120305398A1 (en) 2012-12-06
US8262883B2 (en) 2012-09-11
DE502004000991D1 (de) 2006-08-31
EP1603678B1 (de) 2006-07-19

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