ATE333461T1 - Neue 8a- und 9a-lactame mit 15 ringatomen - Google Patents

Neue 8a- und 9a-lactame mit 15 ringatomen

Info

Publication number
ATE333461T1
ATE333461T1 AT00920937T AT00920937T ATE333461T1 AT E333461 T1 ATE333461 T1 AT E333461T1 AT 00920937 T AT00920937 T AT 00920937T AT 00920937 T AT00920937 T AT 00920937T AT E333461 T1 ATE333461 T1 AT E333461T1
Authority
AT
Austria
Prior art keywords
lactames
new
ring atoms
atoms
ring
Prior art date
Application number
AT00920937T
Other languages
English (en)
Inventor
Gorjana Lazarevski
Sulejman Alihodzic
Gabrijela Kobrehel
Stjepan Mutak
Original Assignee
Pliva Istrazivacki Inst D O O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Istrazivacki Inst D O O filed Critical Pliva Istrazivacki Inst D O O
Application granted granted Critical
Publication of ATE333461T1 publication Critical patent/ATE333461T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
AT00920937T 1999-04-20 2000-04-19 Neue 8a- und 9a-lactame mit 15 ringatomen ATE333461T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HR990116A HRP990116B1 (en) 1999-04-20 1999-04-20 NOVEL 8a AND 9a- 15-MEMBERED LACTAMES

Publications (1)

Publication Number Publication Date
ATE333461T1 true ATE333461T1 (de) 2006-08-15

Family

ID=10946907

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00920937T ATE333461T1 (de) 1999-04-20 2000-04-19 Neue 8a- und 9a-lactame mit 15 ringatomen

Country Status (33)

Country Link
US (1) US6593360B1 (de)
EP (1) EP1181298B1 (de)
JP (1) JP2002542254A (de)
KR (1) KR20020007379A (de)
CN (1) CN1246327C (de)
AR (1) AR028823A1 (de)
AT (1) ATE333461T1 (de)
AU (1) AU772272B2 (de)
BG (1) BG65281B1 (de)
BR (1) BR0009943A (de)
CA (1) CA2370273A1 (de)
CZ (1) CZ20013730A3 (de)
DE (1) DE60029439T2 (de)
DK (1) DK1181298T3 (de)
EA (1) EA003928B1 (de)
EE (1) EE04553B1 (de)
ES (1) ES2267519T3 (de)
GE (1) GEP20032929B (de)
HK (1) HK1049842B (de)
HR (1) HRP990116B1 (de)
HU (1) HUP0200868A3 (de)
IL (1) IL145990A0 (de)
IS (1) IS6110A (de)
MX (1) MXPA01010627A (de)
NO (1) NO320704B1 (de)
NZ (1) NZ515279A (de)
PL (1) PL351523A1 (de)
PT (1) PT1181298E (de)
SK (1) SK14942001A3 (de)
TR (1) TR200103019T2 (de)
UA (1) UA72246C2 (de)
WO (1) WO2000063223A1 (de)
ZA (1) ZA200108481B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0025688D0 (en) * 2000-10-19 2000-12-06 Glaxo Group Ltd Macrolides
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
US7435805B2 (en) * 2003-05-30 2008-10-14 Glaxpsmithkline Istrazivacki O-alkyl macrolide and azalide derivatives and regioselective process for their preparation
WO2006120541A1 (en) 2005-05-10 2006-11-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ether linked macrolides useful for the treatment of microbial infections
BR112015025159A2 (pt) * 2013-04-04 2017-07-18 Harvard College macrolídeos e métodos de sua preparação e uso
HK1242920A1 (zh) 2014-10-08 2018-07-06 哈佛大学的校长及成员们 14-元酮内酯及其制备和使用方法
WO2016154591A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
SI9011409A (en) * 1990-07-18 1995-10-31 Pliva Pharm & Chem Works O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
CA2253338C (en) * 1996-05-07 2007-05-08 Abbott Laboratories 6-o-substituted erythromycins and method for making them
AU1082599A (en) * 1997-10-16 1999-05-03 Merck & Co., Inc. 8a-azalides, compositions containing such compounds and methods of treatment
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides

Also Published As

Publication number Publication date
DE60029439T2 (de) 2007-02-01
GEP20032929B (en) 2003-03-25
IS6110A (is) 2001-10-16
EA003928B1 (ru) 2003-10-30
BG106117A (en) 2002-07-31
EE200100544A (et) 2003-02-17
JP2002542254A (ja) 2002-12-10
BR0009943A (pt) 2002-01-08
AU4134700A (en) 2000-11-02
HUP0200868A2 (hu) 2002-07-29
MXPA01010627A (es) 2002-06-04
PT1181298E (pt) 2006-11-30
HK1049842A1 (en) 2003-05-30
SK14942001A3 (sk) 2002-08-06
HUP0200868A3 (en) 2003-03-28
EP1181298B1 (de) 2006-07-19
HRP990116B1 (en) 2007-10-31
PL351523A1 (en) 2003-05-05
AR028823A1 (es) 2003-05-28
ZA200108481B (en) 2003-03-26
IL145990A0 (en) 2002-07-25
CZ20013730A3 (cs) 2002-04-17
ES2267519T3 (es) 2007-03-16
HRP990116A2 (en) 2001-10-31
NO320704B1 (no) 2006-01-16
EE04553B1 (et) 2005-10-17
NO20015068D0 (no) 2001-10-18
CA2370273A1 (en) 2000-10-26
HK1049842B (zh) 2006-09-22
AU772272B2 (en) 2004-04-22
DK1181298T3 (da) 2006-11-13
KR20020007379A (ko) 2002-01-26
US6593360B1 (en) 2003-07-15
CN1362964A (zh) 2002-08-07
DE60029439D1 (de) 2006-08-31
EA200101103A1 (ru) 2002-04-25
CN1246327C (zh) 2006-03-22
UA72246C2 (uk) 2005-02-15
TR200103019T2 (tr) 2002-01-21
WO2000063223A1 (en) 2000-10-26
EP1181298A1 (de) 2002-02-27
NZ515279A (en) 2003-04-29
NO20015068L (no) 2001-12-13
BG65281B1 (bg) 2007-11-30

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