ATE333868T1 - Verwendung von pyridoxamin für die behandlung und unterdrückung von komplikationen im zusammenhang mit adipositas - Google Patents
Verwendung von pyridoxamin für die behandlung und unterdrückung von komplikationen im zusammenhang mit adipositasInfo
- Publication number
- ATE333868T1 ATE333868T1 AT01992569T AT01992569T ATE333868T1 AT E333868 T1 ATE333868 T1 AT E333868T1 AT 01992569 T AT01992569 T AT 01992569T AT 01992569 T AT01992569 T AT 01992569T AT E333868 T1 ATE333868 T1 AT E333868T1
- Authority
- AT
- Austria
- Prior art keywords
- obesity
- pyridoxamine
- suppression
- treatment
- product formation
- Prior art date
Links
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 title abstract 4
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 235000008151 pyridoxamine Nutrition 0.000 title abstract 2
- 239000011699 pyridoxamine Substances 0.000 title abstract 2
- 230000001629 suppression Effects 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 108010005094 Advanced Glycation End Products Proteins 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 206010011086 Coronary artery occlusion Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 210000000709 aorta Anatomy 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 210000000329 smooth muscle myocyte Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24563000P | 2000-11-02 | 2000-11-02 | |
| US31578901P | 2001-08-29 | 2001-08-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE333868T1 true ATE333868T1 (de) | 2006-08-15 |
Family
ID=26937355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01992569T ATE333868T1 (de) | 2000-11-02 | 2001-11-02 | Verwendung von pyridoxamin für die behandlung und unterdrückung von komplikationen im zusammenhang mit adipositas |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20020128295A1 (de) |
| EP (1) | EP1341532B1 (de) |
| AT (1) | ATE333868T1 (de) |
| AU (1) | AU2002218002A1 (de) |
| DE (1) | DE60121794D1 (de) |
| WO (1) | WO2002036109A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7030146B2 (en) * | 1996-09-10 | 2006-04-18 | University Of South Carolina | Methods for treating diabetic neuropathy |
| WO2001013900A2 (en) | 1999-08-24 | 2001-03-01 | Medicure International Inc. | Compositions for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds |
| US7442689B2 (en) | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| US20090082407A1 (en) * | 2004-06-18 | 2009-03-26 | Biostratum, Inc. | Pyridoxamine for the Treatment of Diabetic Kidney Disease |
| PL1643999T3 (pl) * | 2003-06-20 | 2012-02-29 | Nephrogenex Inc | Pirydoksamina do zastosowania w leczeniu nefropatii cukrzycowej w cukrzycy typu II |
| WO2005077902A2 (en) * | 2004-02-09 | 2005-08-25 | Biostratum, Inc. | Methods for the synthesis of pyridoxamine |
| JPWO2006028007A1 (ja) * | 2004-09-06 | 2008-05-08 | 興和株式会社 | 糸球体疾患治療剤 |
| DE102004050353A1 (de) * | 2004-10-15 | 2006-04-20 | Basf Ag | Verwendung stabiler Ammoniumsalze der Liponsäure zur Behandlung diabetischer und weiterer Störungen |
| US10975033B2 (en) * | 2011-07-12 | 2021-04-13 | Vanderbilt University | Methods for treating inflammation and hypertension with γ-ketoaldehyde skavengers |
| HUE066390T2 (hu) | 2017-04-27 | 2024-07-28 | Univ Vanderbilt | Eljárások ateroszklerózis kezelésére gamma-ketoaldehid-szkevendzserekkel |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5288716A (en) * | 1987-02-18 | 1994-02-22 | Ulrich Speck | Use of pyridoxine derivatives in the prevention and treatment of hyperlipidaemia and atherosclerosis |
| US6228858B1 (en) * | 1995-09-12 | 2001-05-08 | University Of Kansas Medical Center | Advanced glycation end-product intermediaries and post-amadori inhibition |
| AU1112500A (en) * | 1998-10-14 | 2000-05-01 | Kansas University Medical Center Research Institute, Inc. | Methods for inhibiting diabetic complications |
| ATE241982T1 (de) * | 1998-10-22 | 2003-06-15 | Univ South Carolina | Verfahren zur hemmung von diabetischen komplikationen |
-
2001
- 2001-11-02 AT AT01992569T patent/ATE333868T1/de not_active IP Right Cessation
- 2001-11-02 EP EP01992569A patent/EP1341532B1/de not_active Expired - Lifetime
- 2001-11-02 DE DE60121794T patent/DE60121794D1/de not_active Expired - Lifetime
- 2001-11-02 US US10/000,752 patent/US20020128295A1/en not_active Abandoned
- 2001-11-02 AU AU2002218002A patent/AU2002218002A1/en not_active Abandoned
- 2001-11-02 WO PCT/US2001/045415 patent/WO2002036109A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1341532B1 (de) | 2006-07-26 |
| EP1341532A2 (de) | 2003-09-10 |
| US20020128295A1 (en) | 2002-09-12 |
| WO2002036109A2 (en) | 2002-05-10 |
| AU2002218002A1 (en) | 2002-05-15 |
| WO2002036109A3 (en) | 2003-05-30 |
| DE60121794D1 (de) | 2006-09-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |