ATE33496T1 - PROCESS FOR THE PRODUCTION OF ORGANIC OLIGOSACCHARIDS ACCORDING TO FRAGMENTS OF NATURAL MUCO-POLYSACCHARIDS, THE OBTAINED OLIGOSACCHARIDS AND THEIR BIOLOGICAL USE. - Google Patents
PROCESS FOR THE PRODUCTION OF ORGANIC OLIGOSACCHARIDS ACCORDING TO FRAGMENTS OF NATURAL MUCO-POLYSACCHARIDS, THE OBTAINED OLIGOSACCHARIDS AND THEIR BIOLOGICAL USE.Info
- Publication number
- ATE33496T1 ATE33496T1 AT83400110T AT83400110T ATE33496T1 AT E33496 T1 ATE33496 T1 AT E33496T1 AT 83400110 T AT83400110 T AT 83400110T AT 83400110 T AT83400110 T AT 83400110T AT E33496 T1 ATE33496 T1 AT E33496T1
- Authority
- AT
- Austria
- Prior art keywords
- oligosaccharids
- fragments
- organic
- polysaccharids
- muco
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000012634 fragment Substances 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229920001542 oligosaccharide Polymers 0.000 abstract 2
- 150000002482 oligosaccharides Chemical class 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 229920002683 Glycosaminoglycan Polymers 0.000 abstract 1
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- MSWZFWKMSRAUBD-IVMDWMLBSA-N glucosamine group Chemical group OC1[C@H](N)[C@@H](O)[C@H](O)[C@H](O1)CO MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 abstract 1
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Process for the organic synthesis of oligosaccharides and derivatives thereof. The invention relates to a process for the organic synthesis of oligosaccharides constituting or comprising fragments of acid mucopolysaccharides comprising the reaction of two compounds constituted or terminated by units of glucosamine structure and of uronic acid structure respectively, said units being specifically substituted. This process particularly enables valuable anticoagulant drugs to be obtained. (No figure)
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8200621A FR2519987A1 (en) | 1982-01-15 | 1982-01-15 | Uronic acid derivs. - useful as glycoside intermediates or hapten(s) |
| FR8201575A FR2520744A1 (en) | 1982-02-01 | 1982-02-01 | Uronic acid derivs. - useful as glycoside intermediates or hapten(s) |
| FR8202526A FR2521566A1 (en) | 1982-02-16 | 1982-02-16 | Antithrombotic oligosaccharide fragments of muco-polysaccharide prodn. - by reacting uronic acid and glucosamine units |
| FR8209392A FR2527614A1 (en) | 1982-05-28 | 1982-05-28 | Uronic acid derivs. - useful as glycoside intermediates or hapten(s) |
| FR8210892A FR2528854A1 (en) | 1982-06-22 | 1982-06-22 | Antithrombotic oligosaccharide fragments of muco-polysaccharide prodn. - by reacting uronic acid and glucosamine units |
| FR8210891A FR2528853A1 (en) | 1982-06-22 | 1982-06-22 | Antithrombotic oligosaccharide fragments of muco-polysaccharide prodn. - by reacting uronic acid and glucosamine units |
| FR8211679A FR2529557A1 (en) | 1982-07-02 | 1982-07-02 | New disaccharides containing an alpha -L-idopyranose unit, and their preparation |
| FR8213804A FR2531436A1 (en) | 1982-08-06 | 1982-08-06 | Substituted pentasaccharides possessing biological properties, their preparation and their uses as medicaments |
| FR8215803A FR2533219A1 (en) | 1982-09-20 | 1982-09-20 | New disaccharides composed of units having a D-glucosamine and L-iduronic acid structure and method for preparing them |
| FR8215804A FR2533220A1 (en) | 1982-09-20 | 1982-09-20 | New disaccharides composed of units having a D-glucuronic acid and D-glucosamine structure and method for preparing them |
| FR8218003A FR2535324A1 (en) | 1982-10-27 | 1982-10-27 | PERFECTED STATION FOR THE PURIFICATION OF WASTEWATER |
| EP83400110A EP0084999B1 (en) | 1982-01-15 | 1983-01-17 | Process for the preparation of organic oligosaccharides, corresponding to fragments of natural muco-polysaccharides, oligosaccharides obtained and their biological applications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE33496T1 true ATE33496T1 (en) | 1988-04-15 |
Family
ID=27581614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83400110T ATE33496T1 (en) | 1982-01-15 | 1983-01-17 | PROCESS FOR THE PRODUCTION OF ORGANIC OLIGOSACCHARIDS ACCORDING TO FRAGMENTS OF NATURAL MUCO-POLYSACCHARIDS, THE OBTAINED OLIGOSACCHARIDS AND THEIR BIOLOGICAL USE. |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP2510454B2 (en) |
| AT (1) | ATE33496T1 (en) |
| CA (1) | CA1265132A (en) |
| DE (2) | DE3376265D1 (en) |
| DK (1) | DK174348B1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10072039B2 (en) | 2013-07-25 | 2018-09-11 | Scinopharm Taiwan, Ltd. | Process for the production of Fondaparinux sodium |
| EP3024840B1 (en) * | 2013-07-25 | 2019-10-02 | ScinoPharm Taiwan, Ltd. | Process for the production of fondaparinux sodium |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
| AT377493B (en) * | 1979-09-19 | 1985-03-25 | Wiedmer Ernst | SCREW CAP WITH A GUARANTEE RING FOR A CONTAINER TO INDICATE THE FIRST OPENING OF THE CONTAINER |
| IL61201A (en) * | 1979-10-05 | 1984-09-30 | Choay Sa | Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them |
| FR2504535B1 (en) * | 1981-04-28 | 1987-08-14 | Choay Sa | DISACCHARIDES DERIVED FROM URONIC ACID AND GLUCOSAMINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR THE CONTROL OF BLOOD COAGULATION |
-
1983
- 1983-01-13 CA CA000419417A patent/CA1265132A/en not_active Expired
- 1983-01-14 DK DK14383A patent/DK174348B1/en not_active IP Right Cessation
- 1983-01-17 DE DE8383400110T patent/DE3376265D1/en not_active Expired
- 1983-01-17 DE DE2002199025 patent/DE10299025I2/en active Active
- 1983-01-17 AT AT83400110T patent/ATE33496T1/en active
-
1992
- 1992-04-08 JP JP4115407A patent/JP2510454B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05331182A (en) | 1993-12-14 |
| JP2510454B2 (en) | 1996-06-26 |
| CA1265132A (en) | 1990-01-30 |
| DK14383D0 (en) | 1983-01-14 |
| DE3376265D1 (en) | 1988-05-19 |
| DK14383A (en) | 1983-07-16 |
| DK174348B1 (en) | 2002-12-23 |
| DE10299025I2 (en) | 2002-11-07 |
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