ATE336266T1 - Anwendung von metalloporphyrinen zur behandlung von arteriosklerose - Google Patents

Anwendung von metalloporphyrinen zur behandlung von arteriosklerose

Info

Publication number
ATE336266T1
ATE336266T1 AT03253898T AT03253898T ATE336266T1 AT E336266 T1 ATE336266 T1 AT E336266T1 AT 03253898 T AT03253898 T AT 03253898T AT 03253898 T AT03253898 T AT 03253898T AT E336266 T1 ATE336266 T1 AT E336266T1
Authority
AT
Austria
Prior art keywords
treatment
metalloporphyrins
arteriosclerosis
application
radiation treatment
Prior art date
Application number
AT03253898T
Other languages
English (en)
Inventor
Edwin L Adair
Original Assignee
Adair Edwin Lloyd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/176,558 external-priority patent/US6750037B2/en
Application filed by Adair Edwin Lloyd filed Critical Adair Edwin Lloyd
Application granted granted Critical
Publication of ATE336266T1 publication Critical patent/ATE336266T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
AT03253898T 2002-06-21 2003-06-19 Anwendung von metalloporphyrinen zur behandlung von arteriosklerose ATE336266T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/176,558 US6750037B2 (en) 1999-12-27 2002-06-21 Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US10/215,881 US6753160B2 (en) 2002-06-21 2002-08-08 Method of using metaloporphyrins for treatment of arteriosclerotic lesions

Publications (1)

Publication Number Publication Date
ATE336266T1 true ATE336266T1 (de) 2006-09-15

Family

ID=29718497

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03253898T ATE336266T1 (de) 2002-06-21 2003-06-19 Anwendung von metalloporphyrinen zur behandlung von arteriosklerose

Country Status (5)

Country Link
US (1) US7067276B2 (de)
EP (2) EP1679083A3 (de)
JP (1) JP2004131467A (de)
AT (1) ATE336266T1 (de)
DE (1) DE60307545T2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110034769A1 (en) 1997-10-06 2011-02-10 Micro-Imaging Solutions Llc Reduced area imaging device incorporated within wireless endoscopic devices
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
GB0424294D0 (en) * 2004-11-03 2004-12-01 Elam T Ltd Buffer layer
US8447387B2 (en) * 2006-04-10 2013-05-21 Tong Xu Method and apparatus for real-time tumor tracking by detecting annihilation gamma rays from low activity position isotope fiducial markers
US9733187B2 (en) * 2015-03-06 2017-08-15 King Saud University Method of detecting bladder cancer by optical analysis of bodily fluids
JP7865983B2 (ja) 2021-03-12 2026-05-26 ストライカー・ユーロピアン・オペレーションズ・リミテッド 腫瘍組織を検出および除去するための神経外科的方法およびシステム

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3394369A (en) 1965-08-11 1968-07-23 Itt Display device having light spot projected on screen illuminated by plural colored beams
US3846490A (en) 1972-02-24 1974-11-05 N Aronova Method of producing zeta-aminolevulinic acid hydrochloride
US3973129A (en) 1975-01-10 1976-08-03 Bell Telephone Laboratories, Incorporated Fluorimetric apparatus and method for analysis of body fluid
US4937187A (en) 1983-02-04 1990-06-26 Brown University Research Foundation Methods for separating malignant cells from clinical specimens
EP0330801A1 (de) 1983-02-08 1989-09-06 Schering Aktiengesellschaft Ferromagnetische, diamagnetische oder paramagnetische Partikel, die in der Diagnose und Behandlung von Krankheiten nützlich sind
US4939240A (en) 1983-03-04 1990-07-03 Health Research, Inc. Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy
US5122453A (en) 1984-03-28 1992-06-16 Technicon Instruments Corporation Method for discriminating surface stained lymphocytes
US4977177A (en) 1985-04-30 1990-12-11 Nippon Petrochemicals Company, Ltd. Tetrapyrrole polyaminomonocarboxylic acid therapeutic agents
US4897444A (en) 1985-05-31 1990-01-30 The Research Foundation Of The State University Of New York Immobilized fluorogenic substrates for enzymes; and processes for their preparation
US4772691A (en) 1985-06-05 1988-09-20 The Medical College Of Wisconsin, Inc. Chemically cleavable nucleotides
US5162231A (en) * 1989-10-25 1992-11-10 Cole Dean A Method of using 5,10,15,20-tetrakis(carboxyphenyl)porphine for detecting cancers of the lung
US4920143A (en) 1987-04-23 1990-04-24 University Of British Columbia Hydro-monobenzoporphyrin wavelength-specific cytotoxic agents
US5283255A (en) 1987-01-20 1994-02-01 The University Of British Columbia Wavelength-specific cytotoxic agents
US5270171A (en) 1987-03-06 1993-12-14 Boris Cercek Cancer-associated SCM-recognition factor, preparation and method of use
US4886831A (en) 1987-03-16 1989-12-12 The Regents Of The University Of California Medical uses for phycocyanin
US4905670A (en) 1988-12-28 1990-03-06 Adair Edwin Lloyd Apparatus for cervical videoscopy
US5143054A (en) 1988-12-28 1992-09-01 Adair Edwin Lloyd Cervical videoscope with detachable camera unit
US5026368A (en) 1988-12-28 1991-06-25 Adair Edwin Lloyd Method for cervical videoscopy
US5149708A (en) 1989-06-07 1992-09-22 University Of British Columbia Photosensitizing Diels-Alder porphyrin derivatives
US5308608A (en) 1989-06-07 1994-05-03 University Of British Columbia Photosensitizing Diels-Alder porphyrin derivatives
US5422093A (en) 1989-07-28 1995-06-06 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5079262A (en) 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
US5234940A (en) 1989-07-28 1993-08-10 Queen's University Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof
US5955490A (en) 1989-07-28 1999-09-21 Queen's University At Kingston Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
US4997639A (en) 1989-11-27 1991-03-05 Nippon Petrochemicals Company, Limited Method for detecting cholesterol deposited in bodies of mammals
US5087636A (en) 1990-02-20 1992-02-11 University Of British Columbia Method to destroy malignant cells in mononuclear cell populations
WO1992009878A1 (en) 1990-11-23 1992-06-11 Coulter Corporation Method and apparatus for optically screening microscopic cells
US5117466A (en) 1991-04-30 1992-05-26 The United States Of America As Represented By The United States Department Of Energy Integrated fluorescence analysis system
JP3154742B2 (ja) 1991-04-30 2001-04-09 日本石油化学株式会社 哺乳類の動脈硬化症治療剤
US5251613A (en) 1991-05-06 1993-10-12 Adair Edwin Lloyd Method of cervical videoscope with detachable camera
US5627040A (en) 1991-08-28 1997-05-06 Becton Dickinson And Company Flow cytometric method for autoclustering cells
US6096289A (en) 1992-05-06 2000-08-01 Immunomedics, Inc. Intraoperative, intravascular, and endoscopic tumor and lesion detection, biopsy and therapy
EP0654993A1 (de) * 1992-08-17 1995-05-31 Quadra Logic Technologies Inc. Verfahren zur Zerstörung oder Hemmung unerwünschter Zellen oder Gewebe
EP0663900B1 (de) 1992-10-08 1999-09-22 Nycomed Amersham PLC Metall-oxim chelate zur verwendung als röntgenpharmazeutische wirkstoffe
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
EP0610774B1 (de) 1993-02-09 2001-03-28 Becton, Dickinson and Company Automatische Bestimmung der Zellinie schwerer Leukämien durch Flusszytometrie
US5556764A (en) 1993-02-17 1996-09-17 Biometric Imaging, Inc. Method and apparatus for cell counting and cell classification
EP0618191A1 (de) 1993-04-02 1994-10-05 AMERSHAM INTERNATIONAL plc Metall-chelatierende Verbindungen
US5441531A (en) 1993-10-18 1995-08-15 Dusa Pharmaceuticals Inc. Illuminator and methods for photodynamic therapy
US5418169A (en) 1994-03-25 1995-05-23 The Regents Of The University Of California, Office Of Technology Transfer Chromosome characterization using single fluorescent dye
US5616114A (en) 1994-12-08 1997-04-01 Neocardia, Llc. Intravascular radiotherapy employing a liquid-suspended source
US5616342A (en) 1995-04-11 1997-04-01 Pdt, Inc. Emulsioin suitable for administering a poorly water-soluble photosensitizing compound and use thereof
JPH08295639A (ja) 1995-04-27 1996-11-12 Nippon Oil Co Ltd 動脈硬化症診断剤
US5756726A (en) 1995-06-02 1998-05-26 Pharmacyclics, Inc. Methods of producing singlet oxygen using compounds having improved functionalization
US6008211A (en) 1995-07-27 1999-12-28 Pdt Pharmaceuticals, Inc. Photoactivatable compounds comprising benzochlorin and furocoumarin
US5834503A (en) 1996-06-14 1998-11-10 Qlt Phototherapeutics, Inc. Methods to treat arterial plaque
US6443974B1 (en) 1996-07-28 2002-09-03 Biosense, Inc. Electromagnetic cardiac biostimulation
DE69820867T2 (de) * 1997-04-29 2004-11-18 Amersham Health As Lichtbilderzeugungskontrastmitteln
US6019718A (en) 1997-05-30 2000-02-01 Scimed Life Systems, Inc. Apparatus for intravascular radioactive treatment
US6190877B1 (en) 1999-12-27 2001-02-20 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection and fluorescence detection techniques
US6984498B2 (en) 1999-12-27 2006-01-10 Adair Edwin L Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
US6750037B2 (en) * 1999-12-27 2004-06-15 Edwin L. Adair Method of cancer screening primarily utilizing non-invasive cell collection, fluorescence detection techniques, and radio tracing detection techniques
JP2004532251A (ja) * 2001-05-31 2004-10-21 ミラヴァント ファーマシューティカルズ インコーポレイテッド 光線力学療法で使用のメタロテトラピロール系光増感剤
US6566517B2 (en) 2001-06-06 2003-05-20 Brookhaven Science Associates, Llc Metalloporphyrins and their uses as imageable tumor-targeting agents for radiation therapy

Also Published As

Publication number Publication date
EP1374912A1 (de) 2004-01-02
DE60307545D1 (de) 2006-09-28
EP1374912B1 (de) 2006-08-16
JP2004131467A (ja) 2004-04-30
US7067276B2 (en) 2006-06-27
DE60307545T2 (de) 2007-10-04
EP1679083A2 (de) 2006-07-12
US20040202609A1 (en) 2004-10-14
EP1679083A3 (de) 2006-08-02

Similar Documents

Publication Publication Date Title
US20240293029A1 (en) Portable imaging devices and systems for real-time visualization of bacteria and related methods
ATE290690T1 (de) Radiomarkierte photosensitizer zum nachweis von krebs.
Wilder‐Smith et al. Optical diagnostics in the oral cavity: an overview
Yazici et al. In vitro comparison of the efficacy of CarisolvTM and conventional rotary instrument in caries removal
ATE291878T1 (de) Verfahren zur vermeidung von fluoreszenzlöschung
EA199900695A1 (ru) Проникновение анестезирующих средств для местного воздействия, осуществляемое с помощью лазера
WO2001059423A3 (en) Multiphoton excitation through optical fibers for fluorescence spectroscopy
JP2017019818A (ja) 皮膚および創傷における使用のための組成物
NZ334191A (en) Method for improved selectivity in photo-activation and detection of molecular diagnostic agents
EA200602077A1 (ru) Активируемые частицы, их получение и применение
DE60012849D1 (de) Gerät zur Behandlung von wachsenden, erweiterten oder missgebildeten Blutgefässen
WO2000021576A3 (en) Method for viewing tumor tissue located within a body cavity
ATE264862T1 (de) Chlorin- und bakteriochlorin-aminophenyldtpa konjugate als mr kontrastmittel und radiopharmazeutika
NO994932L (no) Blandinger og fremgangsmåter for behandling og diagnose av brystkreft
ATE298341T1 (de) Metallsubstituierte, nicht zentrosymmetrische phthalocyanin-analoga, deren herstellung und verwendung zur photodynamischen therapie, und als in-vivo-diagnostikum
EP1629281A4 (de) Diagnoseverfahren für atherosklerose
ATE291879T1 (de) Verfahren zur vermeidung von fluoreszenzlöschung
DE60307545D1 (de) Anwendung von Metalloporphyrinen zur Behandlung von Arteriosklerose
Pai et al. Chemical analysis of dentin surfaces after Carisolv treatment
DE60226324D1 (de) Glykopeptide, deren herstellung und verwendung in der diagnose oder behandlung von multipler sklerose
WO2022269877A1 (ja) 発光体または口腔内組織体の識別装置、及び口腔内組織体の検査装置
RU2003125544A (ru) Способ подготовки каналов зубов к пломбированию
Muruppel et al. Laser Assisted Diagnostics
RU97111617A (ru) Способ диагностики и лечения твердых тканей зуба и его отложений
Svanberg Medical diagnostics using laser-induced fluorescence

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties