ATE338135T1 - Induziertes genexpressionssystem basierend auf ecdysonrezeptoren - Google Patents
Induziertes genexpressionssystem basierend auf ecdysonrezeptorenInfo
- Publication number
- ATE338135T1 ATE338135T1 AT01922524T AT01922524T ATE338135T1 AT E338135 T1 ATE338135 T1 AT E338135T1 AT 01922524 T AT01922524 T AT 01922524T AT 01922524 T AT01922524 T AT 01922524T AT E338135 T1 ATE338135 T1 AT E338135T1
- Authority
- AT
- Austria
- Prior art keywords
- ecdyson
- receptors
- gene expression
- system based
- expression system
- Prior art date
Links
- UPEZCKBFRMILAV-UHFFFAOYSA-N alpha-Ecdysone Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C(O)CCC(C)(C)O)C)CCC33O)C)C3=CC(=O)C21 UPEZCKBFRMILAV-UHFFFAOYSA-N 0.000 title 1
- 230000014509 gene expression Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- High Energy & Nuclear Physics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19135500P | 2000-03-22 | 2000-03-22 | |
| US26979901P | 2001-02-20 | 2001-02-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE338135T1 true ATE338135T1 (de) | 2006-09-15 |
Family
ID=26886975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01922524T ATE338135T1 (de) | 2000-03-22 | 2001-03-21 | Induziertes genexpressionssystem basierend auf ecdysonrezeptoren |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7091038B2 (de) |
| EP (1) | EP1266015B1 (de) |
| JP (1) | JP5031967B2 (de) |
| CN (1) | CN1304578C (de) |
| AR (1) | AR028276A1 (de) |
| AT (1) | ATE338135T1 (de) |
| AU (2) | AU2001249315A1 (de) |
| CA (1) | CA2404253C (de) |
| DE (1) | DE60122685T2 (de) |
| MX (1) | MXPA02009157A (de) |
| WO (1) | WO2001070816A2 (de) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040033600A1 (en) | 2001-03-21 | 2004-02-19 | Palli Subba Reddy | Ecdysone receptor-based inducible gene expression system |
| US8105825B2 (en) * | 2000-10-03 | 2012-01-31 | Intrexon Corporation | Multiple inducible gene regulation system |
| EP1356066A2 (de) * | 2000-10-24 | 2003-10-29 | Syngenta Participations AG | Kontrolle der pflanzengenexpression |
| EP1373470B1 (de) | 2001-02-20 | 2013-04-24 | Intrexon Corporation | Neue substitutionsmutantenrezeptoren und ihre verwendung in einem induzierbaren genexpressionssystem auf basis eines nukleären rezeptors |
| JP4955904B2 (ja) | 2001-02-20 | 2012-06-20 | イントレキソン コーポレーション | 新規エクジソン受容体/無脊椎動物レチノイドx受容体−ベースの誘導性遺伝子発現システム |
| WO2002066614A2 (en) * | 2001-02-20 | 2002-08-29 | Rheogene Holdings, Inc. | Chimeric retinoid x receptors and their use in a novel ecdysone receptor-based inducible gene expression system |
| EP1534738B1 (de) | 2001-02-20 | 2012-06-20 | Intrexon Corporation | Neue substitutionsmutantenrezeptoren und ihre verwendung in einem induzierbaren genexpressionsystem auf grundlage eines nukleären rezeptors |
| DE10244149A1 (de) * | 2001-09-25 | 2003-04-30 | Werner Keber | Verfahren und Einrichtung zum Verhindern einer unzulässigen Flugannäherung von Flugzeugen an zu schützende Bodenobjeke |
| MXPA04002810A (es) | 2001-09-26 | 2005-06-06 | Rheogene Holdings Inc | Acidos nucleicos receptores de ecdisona de saltarilla, polipeptidos, y sus usos. |
| US7919269B2 (en) | 2001-09-26 | 2011-04-05 | Intrexon Corporation | Whitefly ecdysone receptor nucleic acids, polypeptides, and uses thereof |
| WO2003066676A1 (en) * | 2002-02-05 | 2003-08-14 | Geymonat S.P.A. | Production process of recombinant placental growth factor |
| US9154906B2 (en) | 2002-03-28 | 2015-10-06 | Telecommunication Systems, Inc. | Area watcher for wireless network |
| US7375093B2 (en) * | 2002-07-05 | 2008-05-20 | Intrexon Corporation | Ketone ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
| US7422863B2 (en) | 2003-02-07 | 2008-09-09 | Kumiai Chemical Industry Co., Ltd. | Molting hormone receptor and method for screening ligand to the receptor |
| US7304161B2 (en) | 2003-02-10 | 2007-12-04 | Intrexon Corporation | Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
| AU2011202682B2 (en) * | 2003-02-10 | 2013-11-28 | Intrexon Corporation | Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex |
| US7456315B2 (en) | 2003-02-28 | 2008-11-25 | Intrexon Corporation | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
| US8637237B2 (en) | 2003-08-29 | 2014-01-28 | The University Of North Carolina At Greensboro | Methods, compositions, and systems for the identification of species-specific or developmental stage-specific insecticides |
| WO2005022167A2 (en) * | 2003-08-29 | 2005-03-10 | The University Of North Carolina At Greensboro | Compounds that act to modulate insect growth and methods and systems for identifying such compounds |
| US20050164210A1 (en) * | 2004-01-23 | 2005-07-28 | Vivek Mittal | Regulated polymerase III expression systems and related methods |
| US7935510B2 (en) * | 2004-04-30 | 2011-05-03 | Intrexon Corporation | Mutant receptors and their use in a nuclear receptor-based inducible gene expression system |
| JP4517347B2 (ja) * | 2004-07-02 | 2010-08-04 | 国立大学法人北海道大学 | 植物を用いたエストロゲン様物質の検出方法 |
| US8097431B2 (en) * | 2004-08-04 | 2012-01-17 | University Of Utah Research Foundation | Methods and compositions for detecting steroids |
| US8115059B1 (en) | 2005-07-22 | 2012-02-14 | University Of Kentucky Research Foundation | Gene expression modulation system for use in plants and method for modulating gene expression in plants |
| JP2009505955A (ja) | 2005-07-22 | 2009-02-12 | アムゲン インコーポレイティッド | アニリンスルホンアミド誘導体およびそれらの使用 |
| EP2043662B1 (de) | 2006-07-26 | 2015-09-09 | Intrexon Corporation | Verfahren und zusammensetzungen zur behandlung von krankheiten |
| CN101016518B (zh) * | 2006-09-12 | 2010-07-28 | 南方医科大学 | 一种生物杀虫剂筛选模型及其制备方法和应用 |
| WO2008137681A2 (en) * | 2007-05-02 | 2008-11-13 | Intrexon Corporation | Pp1 ligands |
| CA2689137C (en) | 2007-05-29 | 2017-05-02 | Intrexon Corporation | Chiral diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
| CA2698212A1 (en) | 2007-08-23 | 2009-02-26 | Intrexon Corporation | Methods and compositions for diagnosing disease |
| JP2010538647A (ja) * | 2007-09-17 | 2010-12-16 | ローム アンド ハース カンパニー | 植物における生理的応答を改変するための組成物および方法 |
| MX2010003371A (es) | 2007-09-28 | 2010-05-05 | Intrexon Corp | Constructos interruptores genicos terapeuticos y biorreactores para la expresion de moleculas bioterapeuticas y usos de los mismos. |
| BRPI0818287A2 (pt) | 2007-10-08 | 2015-11-03 | Intrexon Corp | células dendríticas manipuladas e usos para o tratamento do câncer. |
| EP2265116A4 (de) * | 2008-03-14 | 2013-02-06 | Intrexon Corp | Steroid-liganden und ihre verwendung bei der gene-switch-modulation |
| RU2573912C2 (ru) | 2008-10-08 | 2016-01-27 | Интрексон Корпорейшн | Сконструированные клетки, экспрессирующие множественные иммуномодуляторы, и их применения |
| CA2752697A1 (en) | 2009-03-05 | 2010-09-10 | Rohm And Haas Company | Control of targeted turnover of key ethylene hormone signaling pathway proteins to modulate ethylene sensitivity in plants |
| KR20130010121A (ko) | 2010-03-23 | 2013-01-25 | 인트렉손 코포레이션 | 치료적 단백질을 조건부로 발현하는 벡터,상기 벡터를 포함하는 숙주 세포 및 이의 용도 |
| CA2811297C (en) | 2010-09-26 | 2016-10-25 | Donald O'keefe | Method of recombinant macromolecular production |
| JP6189754B2 (ja) | 2011-03-04 | 2017-08-30 | イントレキソン コーポレーション | タンパク質を条件的に発現するベクター |
| WO2012145572A1 (en) | 2011-04-20 | 2012-10-26 | The Trustees Of The University Of Pennsylvania | Regimens and compositions for aav-mediated passive immunization of airborne pathogens |
| US9127024B2 (en) | 2013-03-15 | 2015-09-08 | Intrexon Corporation | Boron-containing diacylhydrazines |
| WO2015012924A2 (en) | 2013-04-29 | 2015-01-29 | The Trustees Of The University Of Pennsylvania | Tissue preferential codon modified expression cassettes, vectors containing same, and use thereof |
| WO2015009760A1 (en) | 2013-07-15 | 2015-01-22 | Donald Danforth Plant Science Center | Enhanced oil production and stress tolerance in plants |
| CN103555727B (zh) * | 2013-10-14 | 2015-06-10 | 中国水产科学研究院淡水渔业研究中心 | 一种中华绒螯蟹性早熟个体活体分子检测方法 |
| AU2015317862A1 (en) | 2014-09-17 | 2017-04-06 | Intrexon Corporation | Boron-containing diacylhydrazine compounds |
| WO2016160791A1 (en) * | 2015-03-30 | 2016-10-06 | Intrexon Corporation | Ligand inducible polypeptide coupler system |
| EA201792500A1 (ru) | 2015-05-13 | 2018-04-30 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Aav-опосредованная экспрессия антител против гриппа и способы их использования |
| WO2017062953A1 (en) | 2015-10-10 | 2017-04-13 | Intrexon Corporation | Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12 |
| SG11201803934YA (en) | 2015-11-11 | 2018-06-28 | Intrexon Corp | Compositions and methods for expression of multiple biologically active polypeptides from a single vector for treatment of cardiac conditions and other pathologies |
| ES2970865T3 (es) | 2015-12-16 | 2024-05-31 | Gritstone Bio Inc | Identificación, fabricación y uso de neoantígenos |
| CA3025667A1 (en) | 2016-06-08 | 2017-12-14 | Intrexon Corporation | Cd33 specific chimeric antigen receptors |
| UY37343A (es) | 2016-07-25 | 2018-02-28 | Intrexon Corp | Control del fenotipo en plantas |
| WO2018089527A1 (en) | 2016-11-09 | 2018-05-17 | Intrexon Corporation | Frataxin expression constructs |
| CN106589125B (zh) * | 2016-12-23 | 2020-04-14 | 江苏省农业科学院 | 抗绿盲蝽蜕皮激素受体蛋白的单克隆抗体及其用途 |
| EP3568474A1 (de) | 2017-01-10 | 2019-11-20 | Intrexon Corporation | Modulation der expression von polypeptiden über neue genschalterexpressionssysteme |
| JOP20190200A1 (ar) | 2017-02-28 | 2019-08-27 | Univ Pennsylvania | تركيبات نافعة في معالجة ضمور العضل النخاعي |
| PT3589730T (pt) | 2017-02-28 | 2024-02-28 | Univ Pennsylvania | Vetor de vírus adenoassociado (aav) de clado f e suas utilizações |
| UY37620A (es) | 2017-02-28 | 2018-08-31 | Univ Pennsylvania | Vacunas contra la gripe mediadas por aav novedosas |
| CA3065930A1 (en) | 2017-06-07 | 2018-12-13 | Intrexon Corporation | Expression of novel cell tags |
| EP4576103A3 (de) | 2017-10-10 | 2025-08-27 | Gritstone bio, Inc. | Neoantigenidentifizierung mit hotspots |
| CN111630602A (zh) | 2017-11-22 | 2020-09-04 | 磨石肿瘤生物技术公司 | 减少新抗原的接合表位呈递 |
| EP3759131A4 (de) | 2018-02-27 | 2021-12-01 | Gritstone bio, Inc. | Neoantigen-identifizierung mit pan-allelmodellen |
| KR20250136930A (ko) | 2018-03-06 | 2025-09-16 | 프레시전 인코포레이티드 | 사람 파필로마바이러스 백신 및 이의 용도 |
| IL277128B2 (en) | 2018-03-06 | 2025-11-01 | Precigen Inc | Hepatitis b vaccines and uses of the same |
| US12460226B2 (en) | 2018-04-16 | 2025-11-04 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treating duchenne muscular dystrophy |
| CN108913732B (zh) * | 2018-07-31 | 2022-02-08 | 华东理工大学 | 一种莫纳可林j异源生产的方法及应用 |
| CN109810993B (zh) * | 2019-03-25 | 2022-05-31 | 临沂大学 | 一种蝗虫β-D-葡萄糖苷水解酶基因及其应用 |
| WO2020206056A1 (en) | 2019-04-04 | 2020-10-08 | Greenvenus Llc | Peptides and methods of plant protection |
| CN110592095A (zh) * | 2019-09-26 | 2019-12-20 | 浙江海洋大学 | 曼氏无针乌贼维甲酸x受体基因的克隆和表达 |
| US20230111619A1 (en) * | 2019-11-19 | 2023-04-13 | Teknologian Tutkimuskeskus Vtt Oy | Non-viral transcription activation domains and methods and uses related thereto |
| TW202237850A (zh) | 2020-12-01 | 2022-10-01 | 賓州大學委員會 | 具有組織特異性靶向基序的新穎構成物及含有其之組成物 |
| CA3216004A1 (en) | 2021-04-23 | 2022-10-27 | The Trustees Of The University Of Pennsylvania | Novel compositions with brain-specific targeting motifs and compositions containing same |
| EP4409010A1 (de) | 2021-10-02 | 2024-08-07 | The Trustees of The University of Pennsylvania | Neue aav-kapside und diese enthaltende zusammensetzungen |
| CN119317718A (zh) | 2022-01-25 | 2025-01-14 | 宾夕法尼亚州大学信托人 | 用于改善心脏转导和肝脏去靶向的aav衣壳 |
| WO2024130070A2 (en) | 2022-12-17 | 2024-06-20 | The Trustees Of The University Of Pennsylvania | Recombinant aav capsids with cardiac- and skeletal muscle- specific targeting motifs and uses thereof |
| EP4634394A2 (de) | 2022-12-17 | 2025-10-22 | The Trustees of The University of Pennsylvania | Rekombinante aav-mutantenvektoren mit herz- und skelettmuskelspezifischen zielmotiven und zusammensetzungen damit |
| TW202516019A (zh) | 2023-06-29 | 2025-04-16 | 賓州大學委員會 | 具中樞神經系統靶向模體的突變aav及含有其之組成物 |
| WO2025102034A1 (en) | 2023-11-10 | 2025-05-15 | The Trustees Of The University Of Pennsylvania | Gene therapy for barth syndrome |
| WO2025106661A1 (en) | 2023-11-14 | 2025-05-22 | The Trustees Of The University Of Pennsylvania | Compositions with cardiac and skeletal musclespecific targeting motifs and uses thereof |
| CN119817530B (zh) * | 2025-02-25 | 2025-07-15 | 浙江省农业科学院 | 一种利用孤雌生殖辅助家蚕品种选育的方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| JPH11508121A (ja) | 1990-03-22 | 1999-07-21 | ザ ソーク インスティテュート フォア バイオロジカル スタディーズ | 昆虫レチノイドレセプター組成物および方法 |
| ATE293699T1 (de) * | 1995-03-03 | 2005-05-15 | Syngenta Participations Ag | Kontrolle der pflanzengenexpression durch rezeptor-vermittelte transaktivation in gegenwart von einem chemischen ligand |
| CA2200423C (en) * | 1996-03-26 | 2006-12-19 | Sietse Mosselman | Novel estrogen receptor |
| AU734051B2 (en) * | 1996-04-05 | 2001-05-31 | Salk Institute For Biological Studies, The | Hormone-mediated methods for modulating expression of exogenous genes in mammalian systems, and products related thereto |
| US5919667A (en) * | 1996-06-20 | 1999-07-06 | The Salk Institute For Biological Studies | Modular assembly retroviral vectors and uses thereof |
| EP0998560A1 (de) * | 1997-07-10 | 2000-05-10 | The Salk Institute For Biological Studies | Modifizierte lepidoptera-rezeptoren und hybride, multifunktionelle proteine zur regulation der expression von transgenen |
| US6300488B1 (en) | 1997-07-10 | 2001-10-09 | The Salk Institute For Biological Studies | Modified lepidopteran receptors and hybrid multifunctional proteins for use in transcription and regulation of transgene expression |
| JP2003524368A (ja) * | 1997-08-26 | 2003-08-19 | アリアド ジーン セラピューティクス インコーポレイテッド | ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、dna結合ドメインまたはリガンド結合ドメインを含む融合蛋白 |
| US6333318B1 (en) * | 1998-05-14 | 2001-12-25 | The Salk Institute For Biological Studies | Formulations useful for modulating expression of exogenous genes in mammalian systems, and products related thereto |
| US6258603B1 (en) * | 1998-06-17 | 2001-07-10 | Rohm And Haas Company | Ligands for modulating the expression of exogenous genes via an ecdysone receptor complex |
-
2001
- 2001-03-21 AU AU2001249315A patent/AU2001249315A1/en not_active Abandoned
- 2001-03-21 EP EP01922524A patent/EP1266015B1/de not_active Expired - Lifetime
- 2001-03-21 DE DE60122685T patent/DE60122685T2/de not_active Expired - Lifetime
- 2001-03-21 AT AT01922524T patent/ATE338135T1/de active
- 2001-03-21 JP JP2001569016A patent/JP5031967B2/ja not_active Expired - Fee Related
- 2001-03-21 MX MXPA02009157A patent/MXPA02009157A/es active IP Right Grant
- 2001-03-21 WO PCT/US2001/009050 patent/WO2001070816A2/en not_active Ceased
- 2001-03-21 CN CNB018078443A patent/CN1304578C/zh not_active Expired - Fee Related
- 2001-03-21 CA CA2404253A patent/CA2404253C/en not_active Expired - Lifetime
- 2001-03-22 AR ARP010101339A patent/AR028276A1/es active IP Right Grant
- 2001-09-26 US US09/965,703 patent/US7091038B2/en not_active Expired - Lifetime
-
2007
- 2007-02-28 AU AU2007200882A patent/AU2007200882B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003527852A (ja) | 2003-09-24 |
| WO2001070816A2 (en) | 2001-09-27 |
| US7091038B2 (en) | 2006-08-15 |
| CA2404253C (en) | 2014-05-13 |
| CN1422334A (zh) | 2003-06-04 |
| DE60122685D1 (de) | 2006-10-12 |
| CA2404253A1 (en) | 2001-09-27 |
| US20020119521A1 (en) | 2002-08-29 |
| MXPA02009157A (es) | 2004-04-05 |
| AU2007200882B2 (en) | 2011-05-19 |
| WO2001070816A3 (en) | 2002-08-29 |
| EP1266015B1 (de) | 2006-08-30 |
| DE60122685T2 (de) | 2007-08-23 |
| JP5031967B2 (ja) | 2012-09-26 |
| AU2007200882A1 (en) | 2007-03-22 |
| CN1304578C (zh) | 2007-03-14 |
| AU2001249315A1 (en) | 2001-10-03 |
| EP1266015A2 (de) | 2002-12-18 |
| AR028276A1 (es) | 2003-04-30 |
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