ATE338273T1 - Vorrichtung zur halterung und präsentation von mindestens einer mikrokugelmatrix zu lösungen und/oder zu optischen abbildungssystemen - Google Patents
Vorrichtung zur halterung und präsentation von mindestens einer mikrokugelmatrix zu lösungen und/oder zu optischen abbildungssystemenInfo
- Publication number
- ATE338273T1 ATE338273T1 AT00937613T AT00937613T ATE338273T1 AT E338273 T1 ATE338273 T1 AT E338273T1 AT 00937613 T AT00937613 T AT 00937613T AT 00937613 T AT00937613 T AT 00937613T AT E338273 T1 ATE338273 T1 AT E338273T1
- Authority
- AT
- Austria
- Prior art keywords
- holder
- bundles
- bundle
- openings
- presenting
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title 1
- 239000004005 microsphere Substances 0.000 title 1
- 238000012634 optical imaging Methods 0.000 title 1
- 239000000835 fiber Substances 0.000 abstract 1
- 238000003032 molecular docking Methods 0.000 abstract 1
- 239000012768 molten material Substances 0.000 abstract 1
- 230000000717 retained effect Effects 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00646—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports
- B01J2219/00648—Making arrays on substantially continuous surfaces the compounds being bound to beads immobilised on the solid supports by the use of solid beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00707—Processes involving means for analysing and characterising the products separated from the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Display Devices Of Pinball Game Machines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13508999P | 1999-05-20 | 1999-05-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE338273T1 true ATE338273T1 (de) | 2006-09-15 |
Family
ID=22466488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00937613T ATE338273T1 (de) | 1999-05-20 | 2000-05-19 | Vorrichtung zur halterung und präsentation von mindestens einer mikrokugelmatrix zu lösungen und/oder zu optischen abbildungssystemen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6396995B1 (de) |
| EP (1) | EP1190233B1 (de) |
| AT (1) | ATE338273T1 (de) |
| AU (1) | AU779835B2 (de) |
| CA (1) | CA2374596A1 (de) |
| DE (1) | DE60030436T2 (de) |
| WO (1) | WO2000071992A1 (de) |
Families Citing this family (111)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69527585T2 (de) * | 1994-06-08 | 2003-04-03 | Affymetrix, Inc. | Verfahren und Vorrichtung zum Verpacken von Chips |
| US6287850B1 (en) * | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
| USRE43097E1 (en) | 1994-10-13 | 2012-01-10 | Illumina, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
| US6720149B1 (en) * | 1995-06-07 | 2004-04-13 | Affymetrix, Inc. | Methods for concurrently processing multiple biological chip assays |
| US7622294B2 (en) | 1997-03-14 | 2009-11-24 | Trustees Of Tufts College | Methods for detecting target analytes and enzymatic reactions |
| US20030027126A1 (en) | 1997-03-14 | 2003-02-06 | Walt David R. | Methods for detecting target analytes and enzymatic reactions |
| US6327410B1 (en) | 1997-03-14 | 2001-12-04 | The Trustees Of Tufts College | Target analyte sensors utilizing Microspheres |
| JP4294740B2 (ja) | 1997-05-23 | 2009-07-15 | ソレクサ・インコーポレイテッド | 分析物の系列的プロセシングのためのシステムおよび装置 |
| EP1090293B2 (de) | 1998-06-24 | 2019-01-23 | Illumina, Inc. | Dekodierung von matrixartig-angeordneten Sensoren durch Mikropartikel |
| US7510841B2 (en) * | 1998-12-28 | 2009-03-31 | Illumina, Inc. | Methods of making and using composite arrays for the detection of a plurality of target analytes |
| US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| EP1190100B1 (de) | 1999-05-20 | 2012-07-25 | Illumina, Inc. | Kombinatorische entschlüsselung von zufallsnukleinsäurearrays |
| US8481268B2 (en) | 1999-05-21 | 2013-07-09 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| US8080380B2 (en) | 1999-05-21 | 2011-12-20 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
| CA2382157C (en) | 1999-08-18 | 2012-04-03 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
| US7244559B2 (en) * | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7211390B2 (en) | 1999-09-16 | 2007-05-01 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| GB9929668D0 (en) * | 1999-12-15 | 2000-02-09 | Moore David F | Microclamps |
| US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
| US6913884B2 (en) | 2001-08-16 | 2005-07-05 | Illumina, Inc. | Compositions and methods for repetitive use of genomic DNA |
| DK1259643T3 (da) | 2000-02-07 | 2009-02-23 | Illumina Inc | Fremgangsmåde til detektion af nukleinsyre ved anvendelse af universel priming |
| US7361488B2 (en) | 2000-02-07 | 2008-04-22 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
| WO2001057268A2 (en) | 2000-02-07 | 2001-08-09 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
| AU2001239760B2 (en) * | 2000-02-10 | 2005-11-24 | Illumina, Inc. | Array of individual arrays as substrate for bead-based simultaneous processing of samples and manufacturing method therefor |
| US6770441B2 (en) * | 2000-02-10 | 2004-08-03 | Illumina, Inc. | Array compositions and methods of making same |
| ATE412774T1 (de) | 2000-02-16 | 2008-11-15 | Illumina Inc | Parallele genotypisierung mehrerer patientenproben |
| CA2408094A1 (en) * | 2000-05-04 | 2001-11-08 | The Center For Blood Research, Inc. | Colloid compositions for solid phase biomolecular analytical, preparative and identification systems |
| US6595698B2 (en) * | 2000-06-13 | 2003-07-22 | Siwave, Inc. | High density fiber terminator/connector |
| DE10057127A1 (de) * | 2000-11-16 | 2002-06-06 | Schott Glas | Verfahren zum Verbringen einer Vielzahl von Faserenden in eine vorgegebene Position |
| US6633707B1 (en) * | 2000-12-29 | 2003-10-14 | Intel Corporation | Lithographically defined optic array |
| GB2390155B (en) * | 2001-01-03 | 2004-04-21 | Packard Instrument Co Inc | Luminescence imager |
| US7572642B2 (en) | 2001-04-18 | 2009-08-11 | Ambrigen, Llc | Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns |
| US6827500B2 (en) * | 2001-06-29 | 2004-12-07 | Lucent Technologies Inc. | Precision two dimensional optical fiber array |
| US20030015139A1 (en) * | 2001-07-17 | 2003-01-23 | 3M Innovative Properties Company | Protective packaging |
| US7332328B2 (en) | 2001-09-07 | 2008-02-19 | Corning Incorporated | Microcolumn-platform based array for high-throughput analysis |
| WO2003027734A1 (en) * | 2001-09-26 | 2003-04-03 | Shipley Company, Llc | Optical fiber array with variable fiber angle alignment and method for the fabrication thereof |
| US6956114B2 (en) | 2001-10-30 | 2005-10-18 | '454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US6902921B2 (en) | 2001-10-30 | 2005-06-07 | 454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US8765484B2 (en) * | 2002-02-07 | 2014-07-01 | The Regents Of The University Of California | Optically encoded particles |
| AU2003215240A1 (en) | 2002-02-14 | 2003-09-04 | Illumina, Inc. | Automated information processing in randomly ordered arrays |
| EP1535046A4 (de) * | 2002-08-28 | 2006-09-13 | Bionexus Ventures L L C | Screening von antikörpern unter verwendung einer faseroptischen arrayeinrichtung mit der fähigkeit zur gleichzeitigen durchführung mehrerer funktionaler assays |
| US7595883B1 (en) | 2002-09-16 | 2009-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Biological analysis arrangement and approach therefor |
| CA2513899C (en) | 2003-01-29 | 2013-03-26 | 454 Corporation | Methods of amplifying and sequencing nucleic acids |
| US7575865B2 (en) | 2003-01-29 | 2009-08-18 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| US8652774B2 (en) * | 2003-04-16 | 2014-02-18 | Affymetrix, Inc. | Automated method of manufacturing polyer arrays |
| US6816654B1 (en) * | 2003-06-27 | 2004-11-09 | Dimitry Grabbe | Fiber array ferrule and method of making |
| EP1702414A4 (de) * | 2003-12-22 | 2008-04-23 | Univ California Office Of The | Optisch codierte partikel mit graustufenspektren |
| AU2004308380A1 (en) * | 2003-12-22 | 2005-07-14 | The Regents Of The University Of California | Optically encoded particles, system and high-throughput screening |
| US7547424B2 (en) | 2004-09-21 | 2009-06-16 | Van Andel Research Institute | Method and apparatus for making partitioned slides |
| CN100562750C (zh) * | 2005-02-05 | 2009-11-25 | 北京源德生物医学工程有限公司 | 一种搭载试剂盒的传送机构 |
| US20070108465A1 (en) * | 2005-03-10 | 2007-05-17 | The Regents Of The University Of California | Porous microstructure multi layer spectroscopy and biosensing |
| US20060246576A1 (en) | 2005-04-06 | 2006-11-02 | Affymetrix, Inc. | Fluidic system and method for processing biological microarrays in personal instrumentation |
| EP3257949A1 (de) | 2005-06-15 | 2017-12-20 | Complete Genomics Inc. | Nukleinsäureanalyse durch zufällige mischungen von nichtüberlappenden fragmenten |
| US8492098B2 (en) | 2006-02-21 | 2013-07-23 | The Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of reaction components that affect a reaction |
| US11237171B2 (en) | 2006-02-21 | 2022-02-01 | Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of target analyte concentration in solution |
| US9528939B2 (en) | 2006-03-10 | 2016-12-27 | Indx Lifecare, Inc. | Waveguide-based optical scanning systems |
| US7951583B2 (en) * | 2006-03-10 | 2011-05-31 | Plc Diagnostics, Inc. | Optical scanning system |
| US8288157B2 (en) * | 2007-09-12 | 2012-10-16 | Plc Diagnostics, Inc. | Waveguide-based optical scanning systems |
| US9976192B2 (en) | 2006-03-10 | 2018-05-22 | Ldip, Llc | Waveguide-based detection system with scanning light source |
| US9423397B2 (en) | 2006-03-10 | 2016-08-23 | Indx Lifecare, Inc. | Waveguide-based detection system with scanning light source |
| US8675199B2 (en) * | 2006-03-10 | 2014-03-18 | Plc Diagnostics, Inc. | Waveguide-based detection system with scanning light source |
| US20080003667A1 (en) * | 2006-05-19 | 2008-01-03 | Affymetrix, Inc. | Consumable elements for use with fluid processing and detection systems |
| EP4170042A1 (de) | 2006-06-14 | 2023-04-26 | Verinata Health, Inc. | Verfahren zur diagnose fötaler anomalien |
| WO2007147079A2 (en) | 2006-06-14 | 2007-12-21 | Living Microsystems, Inc. | Rare cell analysis using sample splitting and dna tags |
| EP2589668A1 (de) | 2006-06-14 | 2013-05-08 | Verinata Health, Inc | Analyse seltener Zellen mittels Probentrennung und DNA-Etiketten |
| US9586346B2 (en) * | 2006-06-28 | 2017-03-07 | Swinburne University Of Technology | Bead immobilisation method and bead arrays made thereby |
| CA2669131A1 (en) | 2006-11-15 | 2008-05-22 | The University Of British Columbia | Polymorphisms predictive of anthracycline-induced cardiotoxicity |
| EP2171097A2 (de) | 2007-06-29 | 2010-04-07 | Population Genetics Technologies LTD. | Verfahren und zusammensetzungen zur isolierung der varianten von nukleinsäuresequenzen |
| JP5503540B2 (ja) | 2007-08-30 | 2014-05-28 | トラスティーズ・オブ・タフツ・カレッジ | 溶液中の分析物濃度を決定する方法 |
| CN101910399B (zh) * | 2007-10-30 | 2015-11-25 | 考利达基因组股份有限公司 | 用于核酸高通量测序的装置 |
| US9551026B2 (en) | 2007-12-03 | 2017-01-24 | Complete Genomincs, Inc. | Method for nucleic acid detection using voltage enhancement |
| EP2229600A1 (de) * | 2007-12-06 | 2010-09-22 | Koninklijke Philips Electronics N.V. | Optische frontplatte und verfahren zu ihrer herstellung |
| US20090181390A1 (en) * | 2008-01-11 | 2009-07-16 | Signosis, Inc. A California Corporation | High throughput detection of micrornas and use for disease diagnosis |
| US8778667B2 (en) * | 2008-05-29 | 2014-07-15 | Toyo Kohan Co., Ltd. | Method and unit for detection of interactions of biologically relevant molecules |
| GB2461026B (en) * | 2008-06-16 | 2011-03-09 | Plc Diagnostics Inc | System and method for nucleic acids sequencing by phased synthesis |
| US8568659B2 (en) * | 2008-09-11 | 2013-10-29 | Mabgen, Llc | Fiber optic device |
| US8222047B2 (en) * | 2008-09-23 | 2012-07-17 | Quanterix Corporation | Ultra-sensitive detection of molecules on single molecule arrays |
| JP2013509883A (ja) | 2009-11-06 | 2013-03-21 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 臓器移植患者における移植片拒絶反応の非侵襲的診断方法 |
| EP2539717B1 (de) * | 2010-02-22 | 2019-07-24 | PerkinElmer Health Sciences, Inc. | Mikroplattenhalterungssystem und messverfahren |
| CN103026232B (zh) | 2010-03-01 | 2015-02-04 | 匡特里克斯公司 | 扩大用于检测分子或颗粒的测定法中的动态范围的方法和系统 |
| US9678068B2 (en) * | 2010-03-01 | 2017-06-13 | Quanterix Corporation | Ultra-sensitive detection of molecules using dual detection methods |
| US8415171B2 (en) * | 2010-03-01 | 2013-04-09 | Quanterix Corporation | Methods and systems for extending dynamic range in assays for the detection of molecules or particles |
| US8236574B2 (en) | 2010-03-01 | 2012-08-07 | Quanterix Corporation | Ultra-sensitive detection of molecules or particles using beads or other capture objects |
| US8774494B2 (en) | 2010-04-30 | 2014-07-08 | Complete Genomics, Inc. | Method and system for accurate alignment and registration of array for DNA sequencing |
| US9671344B2 (en) | 2010-08-31 | 2017-06-06 | Complete Genomics, Inc. | High-density biochemical array chips with asynchronous tracks for alignment correction by moiré averaging |
| US9880089B2 (en) | 2010-08-31 | 2018-01-30 | Complete Genomics, Inc. | High-density devices with synchronous tracks for quad-cell based alignment correction |
| WO2012051476A1 (en) | 2010-10-15 | 2012-04-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mid-infrared imaging of microarrays |
| EP2463661B1 (de) | 2010-11-15 | 2014-01-08 | F. Hoffmann-La Roche AG | Instrument und Verfahren zur automatisierten Wärmebehandlung von Flüssigkeitsproben |
| US9952237B2 (en) | 2011-01-28 | 2018-04-24 | Quanterix Corporation | Systems, devices, and methods for ultra-sensitive detection of molecules or particles |
| WO2012142301A2 (en) | 2011-04-12 | 2012-10-18 | Quanterix Corporation | Methods of determining a treatment protocol for and/or a prognosis of a patients recovery from a brain injury |
| EP2525211B1 (de) | 2011-05-16 | 2018-01-03 | F. Hoffmann-La Roche AG | Instrument und verfahren zum detektieren von analyten |
| WO2013033073A1 (en) | 2011-08-31 | 2013-03-07 | Ventana Medical Systems, Inc. | Expression of ets related gene (erg) and phosphatase and tensin homolog (pten) correlates with prostate cancer capsular penetration |
| CA3069089A1 (en) | 2011-09-22 | 2013-03-28 | Lineage Biosciences, Inc. | Compositions and methods for analyzing heterogeneous samples |
| US10837879B2 (en) | 2011-11-02 | 2020-11-17 | Complete Genomics, Inc. | Treatment for stabilizing nucleic acid arrays |
| US9803239B2 (en) | 2012-03-29 | 2017-10-31 | Complete Genomics, Inc. | Flow cells for high density array chips |
| US9488823B2 (en) | 2012-06-07 | 2016-11-08 | Complete Genomics, Inc. | Techniques for scanned illumination |
| US9628676B2 (en) | 2012-06-07 | 2017-04-18 | Complete Genomics, Inc. | Imaging systems with movable scan mirrors |
| US9932626B2 (en) | 2013-01-15 | 2018-04-03 | Quanterix Corporation | Detection of DNA or RNA using single molecule arrays and other techniques |
| EP3611262B1 (de) | 2013-03-15 | 2020-11-11 | Lineage Biosciences, Inc. | Verfahren zur sequenzierung des immunrepertoirs |
| DE102013210204A1 (de) * | 2013-05-31 | 2014-12-18 | Gilupi Gmbh | Detektionsvorrichtung zur in vivo und/oder in vitro Anreicherung von Probenmaterial |
| CA2940322C (en) | 2014-02-21 | 2021-05-18 | President And Fellows Of Harvard College | De novo design of allosteric proteins |
| US10018566B2 (en) | 2014-02-28 | 2018-07-10 | Ldip, Llc | Partially encapsulated waveguide based sensing chips, systems and methods of use |
| US10119964B2 (en) * | 2014-12-22 | 2018-11-06 | Digital Biotech, LLC | Multiplex assay strip, beads, device and method |
| WO2016138427A1 (en) | 2015-02-27 | 2016-09-01 | Indx Lifecare, Inc. | Waveguide-based detection system with scanning light source |
| ES3026859T3 (en) | 2017-01-04 | 2025-06-12 | Mgi Tech Co Ltd | Stepwise sequencing by non-labeled reversible terminators or natural nucleotides |
| GB201700936D0 (en) * | 2017-01-19 | 2017-03-08 | Univ Bath | Optical fibre apparatus and method |
| US10379297B2 (en) * | 2017-04-21 | 2019-08-13 | Intuitive Surgical Operations, Inc. | Sealing a fiber bundle end with glass fritting |
| EP3775261B1 (de) | 2018-03-26 | 2025-09-17 | Guangzhou Chengyuan Bioimmunology Technology Co., Ltd. | Zusammensetzungen zielbindender einheiten und verwendungsverfahren |
| CN115427586B (zh) | 2020-03-18 | 2025-03-28 | 深圳华大智造科技股份有限公司 | 大规模平行测序中的恢复阶段 |
| WO2023212290A1 (en) * | 2022-04-29 | 2023-11-02 | Singular Genomics Systems, Inc. | Microplate carrier |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3853658A (en) * | 1971-07-12 | 1974-12-10 | R Ney | Fiber optical image magnifier panel and method of manufacture |
| US4046454A (en) * | 1976-05-18 | 1977-09-06 | Bell Telephone Laboratories, Incorporated | Optical fiber connector |
| DE2740376C3 (de) * | 1977-09-08 | 1980-06-04 | Fa. A. Raymond, 7850 Loerrach | Elastische Klemmhalterung für Rundstäbe mit variablen Durchmessern |
| US5206568A (en) * | 1986-03-26 | 1993-04-27 | Beckman Instruments, Inc. | Coordinated control of stepper motors |
| US4744627A (en) * | 1986-11-03 | 1988-05-17 | General Electric Company | Optical fiber holder |
| US4973128A (en) * | 1989-05-01 | 1990-11-27 | Hodges Marvin P | High gain optical fiber viewing device |
| JP3105624B2 (ja) * | 1992-03-30 | 2000-11-06 | 日本碍子株式会社 | 多心コネクタおよびその製造法 |
| US5589351A (en) | 1994-12-06 | 1996-12-31 | Nps Pharmaceuticals, Inc. | Fluorescence detection apparatus |
| GB2315130B (en) * | 1996-07-10 | 2001-05-09 | Cambridge Imaging Ltd | Improved imaging system for fluorescence assays |
| GB2315131B (en) | 1996-07-10 | 2000-11-29 | Cambridge Imaging Ltd | Improvements in and relating to imaging |
| US6043880A (en) * | 1997-09-15 | 2000-03-28 | Becton Dickinson And Company | Automated optical reader for nucleic acid assays |
| JP3813730B2 (ja) * | 1998-03-19 | 2006-08-23 | 浜松ホトニクス株式会社 | 蛍光測定装置 |
-
2000
- 2000-05-19 AU AU52759/00A patent/AU779835B2/en not_active Expired
- 2000-05-19 WO PCT/US2000/013772 patent/WO2000071992A1/en not_active Ceased
- 2000-05-19 EP EP00937613A patent/EP1190233B1/de not_active Expired - Lifetime
- 2000-05-19 CA CA002374596A patent/CA2374596A1/en not_active Abandoned
- 2000-05-19 US US09/574,962 patent/US6396995B1/en not_active Expired - Lifetime
- 2000-05-19 AT AT00937613T patent/ATE338273T1/de not_active IP Right Cessation
- 2000-05-19 DE DE60030436T patent/DE60030436T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1190233B1 (de) | 2006-08-30 |
| DE60030436D1 (de) | 2006-10-12 |
| CA2374596A1 (en) | 2000-11-30 |
| AU5275900A (en) | 2000-12-12 |
| AU779835B2 (en) | 2005-02-10 |
| EP1190233A1 (de) | 2002-03-27 |
| WO2000071992A1 (en) | 2000-11-30 |
| US6396995B1 (en) | 2002-05-28 |
| DE60030436T2 (de) | 2007-03-29 |
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