ATE340184T1 - Makrolidantibiotika - Google Patents

Makrolidantibiotika

Info

Publication number
ATE340184T1
ATE340184T1 AT01271381T AT01271381T ATE340184T1 AT E340184 T1 ATE340184 T1 AT E340184T1 AT 01271381 T AT01271381 T AT 01271381T AT 01271381 T AT01271381 T AT 01271381T AT E340184 T1 ATE340184 T1 AT E340184T1
Authority
AT
Austria
Prior art keywords
sub
macrolide antibiotic
solvates
prophylaxis
systemic
Prior art date
Application number
AT01271381T
Other languages
English (en)
Inventor
Daniele Andreotti
Stefano Biondi
Sergio Lociuro
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE340184T1 publication Critical patent/ATE340184T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
AT01271381T 2000-12-21 2001-12-20 Makrolidantibiotika ATE340184T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0031312.2A GB0031312D0 (en) 2000-12-21 2000-12-21 Macrolides

Publications (1)

Publication Number Publication Date
ATE340184T1 true ATE340184T1 (de) 2006-10-15

Family

ID=9905640

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01271381T ATE340184T1 (de) 2000-12-21 2001-12-20 Makrolidantibiotika

Country Status (9)

Country Link
US (1) US6900183B2 (de)
EP (1) EP1343797B1 (de)
JP (1) JP2004520314A (de)
AT (1) ATE340184T1 (de)
AU (1) AU2002222296A1 (de)
DE (1) DE60123277T2 (de)
ES (1) ES2272410T3 (de)
GB (1) GB0031312D0 (de)
WO (1) WO2002050092A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003024986A1 (en) * 2001-09-17 2003-03-27 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
US6995143B2 (en) 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US6727229B2 (en) 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
US6720308B1 (en) 2002-11-07 2004-04-13 Enanta Pharmaceuticals, Inc. Anhydrolide derivatives having antibacterial activity
EP1638549A4 (de) 2003-03-10 2011-06-15 Optimer Pharmaceuticals Inc Neue antibakterielle mittel
US6716820B1 (en) 2003-06-05 2004-04-06 Enanta Pharmaceuticals, Inc. 6-O-substituted bicyclic macrolides
US6790835B1 (en) 2003-06-05 2004-09-14 Enanta Pharmaceuticals, Inc. Bicyclic macrolide derivatives
US6765016B1 (en) 2003-06-05 2004-07-20 Enanta Pharmaceuticals, Inc. Bicyclic ketolide derivatives
WO2004108745A2 (en) * 2003-06-05 2004-12-16 Enanta Pharmaceuticals, Inc. 11-12 bicyclic erythromycin derivatives
US20040254126A1 (en) * 2003-06-05 2004-12-16 Yao-Ling Qiu 11-12 Bicyclic erythromycin derivatives
US6774115B1 (en) 2003-06-05 2004-08-10 Enanta Pharmaceuticals, Inc. 6-O-substituted bicyclic ketolides
WO2006120541A1 (en) 2005-05-10 2006-11-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ether linked macrolides useful for the treatment of microbial infections
RU2455308C2 (ru) * 2006-05-01 2012-07-10 Тайсо Фармасьютикал Ко., Лтд. Макролидные производные
CA2661538A1 (en) * 2006-08-24 2008-02-28 Wockhardt Research Centre Novel macrolides and ketolides having antimicrobial activity
EP2214484A4 (de) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc Verfahren zur herstellung von antibakteriellen makrolid-wirkstoffen
JP5711135B2 (ja) 2008-10-24 2015-04-30 センプラ ファーマシューティカルズ，インコーポレイテッド 胃腸疾患を治療するための方法
ES2561332T3 (es) 2009-05-27 2016-02-25 Wockhardt Limited Compuestos cetólidos que tienen actividad antimicrobiana
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
ES2608285T3 (es) 2009-09-10 2017-04-07 Cempra Pharmaceuticals, Inc. Procedimientos para el tratamiento de paludismo, tuberculosis y enfermedades por MAC
MX361413B (es) 2010-03-22 2018-12-05 Cempra Pharmaceuticals Inc Star Formas cristalinas de un macrólido y usos para las mismas.
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
EP2613630A4 (de) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc Wasserstoffbindung zur formung von fluorketoliden zur behandlung von krankheiten
PT2673285T (pt) 2010-12-09 2017-10-19 Wockhardt Ltd Resumo
JP5718488B2 (ja) 2011-03-01 2015-05-13 ウォックハート リミテッド ケトライド中間体の調製方法
NZ700182A (en) 2012-03-27 2017-02-24 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法
AU2017206672A1 (en) 2016-01-12 2018-08-23 Wockhardt Limited Pharmaceutical compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2739620B1 (fr) 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
KR20020008127A (ko) * 1999-03-15 2002-01-29 스티븐 에프. 웨인스톡 항균 활성을 갖는 6-ｏ-치환된 매크롤라이드
EP1114826A3 (de) 1999-12-29 2001-10-31 Pfizer Products Inc. Antibakterielle und prokinetische Makroliden

Also Published As

Publication number Publication date
AU2002222296A1 (en) 2002-07-01
JP2004520314A (ja) 2004-07-08
EP1343797A1 (de) 2003-09-17
US20040082526A1 (en) 2004-04-29
WO2002050092A1 (en) 2002-06-27
DE60123277D1 (de) 2006-11-02
DE60123277T2 (de) 2007-09-13
EP1343797B1 (de) 2006-09-20
GB0031312D0 (en) 2001-02-07
ES2272410T3 (es) 2007-05-01
US6900183B2 (en) 2005-05-31

Similar Documents

Publication Publication Date Title
ATE340184T1 (de) Makrolidantibiotika
AP9801253A0 (en) 9-Oxime erythromycin derivatives.
CA2316919A1 (en) Novel macrolides
BG103945A (bg) Производни на 4"-заместен-9-деоксо-9а-аза-9а- хомоеритромицин а
MXPA03005464A (es) Agentes antivirales.
TR199901127T2 (xx) Antibakteriyel etkili 6-O-ikameli ketolitler.
CA2293397A1 (en) C-4''-substituted macrolide derivatives
AP9801378A0 (en) 9-amino-3- keto erythromycin derivatives.
EA200400536A1 (ru) Макролиды
CA2351429A1 (en) 13-membered azalides and their use as antibiotic agents
PT806941E (pt) Composicoes anti-bacterianas liposomicas de rigidez baixa
CA2359708A1 (en) Ketolide antibiotics
DK0623021T3 (da) 4"-deoxyerythromycinderivater
AU6484199A (en) Carbamate and carbazate ketolide antibiotics
DK0992509T3 (da) Nye makrolid-derivater
AP9801377A0 (en) Tricyclic erythromycin derivatives.
BR9708929A (pt) Composto composição farmacêutica e processos para controlar uma infecção bacteriana em um mamífero e para preparar compostos de macrólidos
WO2004039822A3 (en) 4’’ - modified erythromycin derivatives
MY133397A (en) Novel crystalline forms of a macrolide antibiotic
AP9801235A0 (en) Erythromycin derivatives.
WO2002018353A3 (en) Oxazolidinone chemotherapeutic agents
WO2002057286A3 (en) 9-amino erythromycin derivatives with antibacterial activity
PT952157E (pt) Derivados 9a, 11b-desidro de 9-oxima-3-ceto-6-o-metileritromicina

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties