ATE340184T1 - Makrolidantibiotika - Google Patents

Makrolidantibiotika

Info

Publication number
ATE340184T1
ATE340184T1 AT01271381T AT01271381T ATE340184T1 AT E340184 T1 ATE340184 T1 AT E340184T1 AT 01271381 T AT01271381 T AT 01271381T AT 01271381 T AT01271381 T AT 01271381T AT E340184 T1 ATE340184 T1 AT E340184T1
Authority
AT
Austria
Prior art keywords
sub
macrolide antibiotic
solvates
prophylaxis
systemic
Prior art date
Application number
AT01271381T
Other languages
English (en)
Inventor
Daniele Andreotti
Stefano Biondi
Sergio Lociuro
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE340184T1 publication Critical patent/ATE340184T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
AT01271381T 2000-12-21 2001-12-20 Makrolidantibiotika ATE340184T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0031312.2A GB0031312D0 (en) 2000-12-21 2000-12-21 Macrolides

Publications (1)

Publication Number Publication Date
ATE340184T1 true ATE340184T1 (de) 2006-10-15

Family

ID=9905640

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01271381T ATE340184T1 (de) 2000-12-21 2001-12-20 Makrolidantibiotika

Country Status (9)

Country Link
US (1) US6900183B2 (de)
EP (1) EP1343797B1 (de)
JP (1) JP2004520314A (de)
AT (1) ATE340184T1 (de)
AU (1) AU2002222296A1 (de)
DE (1) DE60123277T2 (de)
ES (1) ES2272410T3 (de)
GB (1) GB0031312D0 (de)
WO (1) WO2002050092A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2460947A1 (en) * 2001-09-17 2003-03-27 Ortho-Mcneil Pharmaceutical, Inc. 6-o-carbamate-11,12-lacto-ketolide antimicrobials
US6995143B2 (en) 2002-02-28 2006-02-07 Basilea Pharmaceutica Ag Macrolides with antibacterial activity
US6727229B2 (en) 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
US6720308B1 (en) 2002-11-07 2004-04-13 Enanta Pharmaceuticals, Inc. Anhydrolide derivatives having antibacterial activity
US7601695B2 (en) 2003-03-10 2009-10-13 Optimer Pharmaceuticals, Inc. Antibacterial agents
US6765016B1 (en) 2003-06-05 2004-07-20 Enanta Pharmaceuticals, Inc. Bicyclic ketolide derivatives
US20040254126A1 (en) * 2003-06-05 2004-12-16 Yao-Ling Qiu 11-12 Bicyclic erythromycin derivatives
US6716820B1 (en) 2003-06-05 2004-04-06 Enanta Pharmaceuticals, Inc. 6-O-substituted bicyclic macrolides
WO2004108745A2 (en) * 2003-06-05 2004-12-16 Enanta Pharmaceuticals, Inc. 11-12 bicyclic erythromycin derivatives
US6790835B1 (en) 2003-06-05 2004-09-14 Enanta Pharmaceuticals, Inc. Bicyclic macrolide derivatives
US6774115B1 (en) 2003-06-05 2004-08-10 Enanta Pharmaceuticals, Inc. 6-O-substituted bicyclic ketolides
JP2008540503A (ja) 2005-05-10 2008-11-20 グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ 細菌感染症の処置に有用なエーテル結合マクロライド
JP5126685B2 (ja) * 2006-05-01 2013-01-23 大正製薬株式会社 マクロライド誘導体
CN101541331A (zh) 2006-08-24 2009-09-23 沃克哈特研究中心 具有抗微生物活性的新颖大环内酯和酮内酯
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
CN107854477A (zh) 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
EP2435460B1 (de) 2009-05-27 2015-01-07 Wockhardt Limited Ketolid-verbindungen mit antimikrobieller wirkung
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
HRP20160168T1 (hr) 2010-03-22 2016-03-25 Cempra Pharmaceuticals Inc Kristalne forme makrolida i njihova uporaba
BR112012029586A2 (pt) 2010-05-20 2016-08-02 Cempra Pharmaceuticals Inc processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
RU2601550C2 (ru) 2010-12-09 2016-11-10 Вокхардт Лимитед Кетолидные соединения
CN103619849B (zh) 2011-03-01 2016-05-25 沃克哈特有限公司 酮内酯中间体的制备方法
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
KR20180101509A (ko) 2016-01-12 2018-09-12 욱크하르트 리미티드 약학 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2739620B1 (fr) * 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
DK1161438T3 (da) * 1999-03-15 2004-08-30 Abbott Lab 6-O-substituerede makrolider, som har antibakteriel aktivitet
EP1114826A3 (de) * 1999-12-29 2001-10-31 Pfizer Products Inc. Antibakterielle und prokinetische Makroliden

Also Published As

Publication number Publication date
GB0031312D0 (en) 2001-02-07
ES2272410T3 (es) 2007-05-01
EP1343797B1 (de) 2006-09-20
DE60123277D1 (de) 2006-11-02
US6900183B2 (en) 2005-05-31
EP1343797A1 (de) 2003-09-17
WO2002050092A1 (en) 2002-06-27
AU2002222296A1 (en) 2002-07-01
JP2004520314A (ja) 2004-07-08
US20040082526A1 (en) 2004-04-29
DE60123277T2 (de) 2007-09-13

Similar Documents

Publication Publication Date Title
DE60123277D1 (de) Makrolidantibiotika
AP9801253A0 (en) 9-Oxime erythromycin derivatives.
CA2316919A1 (en) Novel macrolides
BG103969A (en) C-4"-substituted macrolide derivatives
BG103945A (bg) Производни на 4"-заместен-9-деоксо-9а-аза-9а- хомоеритромицин а
MXPA03005464A (es) Agentes antivirales.
TR199901127T2 (xx) Antibakteriyel etkili 6-O-ikameli ketolitler.
AP9801378A0 (en) 9-amino-3- keto erythromycin derivatives.
CA2292359A1 (en) Novel azalides and methods of making same
EA200400536A1 (ru) Макролиды
CA2351429A1 (en) 13-membered azalides and their use as antibiotic agents
PT806941E (pt) Composicoes anti-bacterianas liposomicas de rigidez baixa
CA2359708A1 (en) Ketolide antibiotics
DK0623021T3 (da) 4"-deoxyerythromycinderivater
AU6484199A (en) Carbamate and carbazate ketolide antibiotics
DK0992509T3 (da) Nye makrolid-derivater
CA2280328A1 (en) C11 carbamates of macrolide antibacterials
BR9708929A (pt) Composto composição farmacêutica e processos para controlar uma infecção bacteriana em um mamífero e para preparar compostos de macrólidos
AP2001002325A0 (en) Novel crystalline forms of a macrolide antibiotic
AP9801235A0 (en) Erythromycin derivatives.
WO2002018353A3 (en) Oxazolidinone chemotherapeutic agents
WO2002018354A8 (en) Oxazolidinones and their use as antibacterial agents

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties