ATE340254T1 - Verfahren zur freisetzung von magnetischen teilchen, die an zelloberflächen gebunden sind - Google Patents

Verfahren zur freisetzung von magnetischen teilchen, die an zelloberflächen gebunden sind

Info

Publication number
ATE340254T1
ATE340254T1 AT96910404T AT96910404T ATE340254T1 AT E340254 T1 ATE340254 T1 AT E340254T1 AT 96910404 T AT96910404 T AT 96910404T AT 96910404 T AT96910404 T AT 96910404T AT E340254 T1 ATE340254 T1 AT E340254T1
Authority
AT
Austria
Prior art keywords
magnetic particles
cell surfaces
particles bonded
releasing magnetic
coating
Prior art date
Application number
AT96910404T
Other languages
English (en)
Inventor
Stephan Miltenti
Original Assignee
Miltenyi Biotec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miltenyi Biotec Inc filed Critical Miltenyi Biotec Inc
Application granted granted Critical
Publication of ATE340254T1 publication Critical patent/ATE340254T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/002—High gradient magnetic separation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Soft Magnetic Materials (AREA)
  • Hard Magnetic Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT96910404T 1995-04-06 1996-03-11 Verfahren zur freisetzung von magnetischen teilchen, die an zelloberflächen gebunden sind ATE340254T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41863995A 1995-04-06 1995-04-06

Publications (1)

Publication Number Publication Date
ATE340254T1 true ATE340254T1 (de) 2006-10-15

Family

ID=23658956

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96910404T ATE340254T1 (de) 1995-04-06 1996-03-11 Verfahren zur freisetzung von magnetischen teilchen, die an zelloberflächen gebunden sind

Country Status (5)

Country Link
EP (1) EP0819250B1 (de)
AT (1) ATE340254T1 (de)
AU (1) AU5360596A (de)
DE (1) DE69636564T2 (de)
WO (1) WO1996031776A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770029A (en) * 1996-07-30 1998-06-23 Soane Biosciences Integrated electrophoretic microdevices
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US6241894B1 (en) * 1997-10-10 2001-06-05 Systemix High gradient magnetic device and method for cell separation or purification
US20040132044A1 (en) * 2001-05-07 2004-07-08 Menachem Ritterband Magnetic beads and uses thereof
US20120156779A1 (en) * 2009-08-27 2012-06-21 Ge Healthcare Bio-Sciences Ab Method for cell expansion
EP2700713B1 (de) 2012-08-21 2016-07-13 Miltenyi Biotec GmbH Untersuchungs- und Anreicherungssystem für die Proteinexpression in eukaryotischen Zellen unter Verwendung einer trizistronischen Expressionskassette
US20190178879A1 (en) * 2012-08-23 2019-06-13 Stemcell Technologies Canada Inc. Compositions and methods for rapid and reversible biomolecular labeling
EP3037170A1 (de) * 2014-12-27 2016-06-29 Miltenyi Biotec GmbH Multisort-Zelltrennverfahren
EP3037820A1 (de) * 2014-12-27 2016-06-29 Miltenyi Biotec GmbH Zellerkennungsverfahren und Reagenzien mit lösbarem Etikettierungsteil
US10871490B2 (en) * 2016-02-29 2020-12-22 Multenyi Biotec, gmbH Assay for detection of chimeric antigen receptor T cells
EP3336546B1 (de) 2016-12-13 2020-07-01 Miltenyi Biotec B.V. & Co. KG Umkehrbare zellmarkierung mit konjugaten mit zwei lösbaren bindungsstellen
CN113677995A (zh) 2019-04-23 2021-11-19 美天施生物科技有限两合公司 使用具有用于增加荧光亮度的接头和酶促可释放荧光部分的缀合物的可逆细胞检测
CA3142108A1 (en) 2019-05-28 2020-12-03 Miltenyi Biotec B.V. & Co. KG Method for generation of genetically modified t cells
WO2021047804A1 (en) 2019-09-11 2021-03-18 Miltenyi Biotec B.V. & Co. KG In vitro method for transduction of t cells in the presence of malignant cells
EP4078178B1 (de) 2019-12-20 2024-10-23 Miltenyi Biotec B.V. & Co. KG Reversible zelldetektion über mhc mit konjugaten mit einer enzymatisch spaltbaren detektionseinheit
KR20220128367A (ko) * 2019-12-31 2022-09-20 엘릭서젠 쎄라퓨틱스, 인크. Zscan4 핵산 및 단백질의 세포 및 조직으로의 온도-기반 일시적 전달
MX2022007905A (es) 2019-12-31 2022-08-25 Elixirgen Therapeutics Inc Administracion transitoria basada en temperatura de acidos nucleicos y proteinas a celulas y tejidos.
EP4204809A1 (de) 2020-08-27 2023-07-05 Miltenyi Biotec B.V. & Co. KG Freisetzbare reagenzien zur zelltrennung
WO2023143179A1 (zh) * 2022-01-28 2023-08-03 南京大学 一种对抗原样本的处理方法和应用
CN119095950A (zh) 2022-04-28 2024-12-06 生物细胞再生有限公司 用于分离靶细胞的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US4714680B1 (en) * 1984-02-06 1995-06-27 Univ Johns Hopkins Human stem cells
JPH0825888B2 (ja) * 1986-01-30 1996-03-13 フレッド ハッチンソン キャンサ− リサ−チ センタ− 免疫選択法
CA1335181C (en) * 1988-10-11 1995-04-11 R. Alan Hardwick System for selective cell separation from cell concentrate
US5385707A (en) * 1988-12-28 1995-01-31 Stefan Miltenyi Metal matrices for use in high gradient magnetic separation of biological materials and method for coating the same
US5081030A (en) * 1989-04-25 1992-01-14 The Johns Hopkins University Release of cells from affinity matrices
GB8929297D0 (en) * 1989-12-29 1990-02-28 Dynal As Method of separation
GB9108047D0 (en) * 1991-04-16 1991-06-05 Mellors Alan The use of pasteurella haemolytica clycoproteinase for human bone marrow haematopoietic primitive stem-cell isolation
WO1994002016A1 (en) * 1992-07-28 1994-02-03 Steven Kessler Methods for positive immunoselection of stem cells

Also Published As

Publication number Publication date
DE69636564D1 (de) 2006-11-02
EP0819250A4 (de) 1998-05-06
EP0819250B1 (de) 2006-09-20
AU5360596A (en) 1996-10-23
WO1996031776A1 (en) 1996-10-10
EP0819250A1 (de) 1998-01-21
DE69636564T2 (de) 2007-06-06

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Legal Events

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