ATE341310T1 - Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome - Google Patents

Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome

Info

Publication number: ATE341310T1
Authority: AT; Austria
Prior art keywords: sugar; dehydration; lipid; liposomes; rehydration
Prior art date: 2000-02-04

Application number

AT01948934T

Other languages

English (en)

Inventor

Brahim Zadi

Original Assignee

Lipoxen Technologies Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-04

Filing date

2001-01-31

Publication date

2006-10-15

2001-01-31 Application filed by Lipoxen Technologies Ltd filed Critical Lipoxen Technologies Ltd

2006-10-15 Application granted granted Critical

2006-10-15 Publication of ATE341310T1 publication Critical patent/ATE341310T1/de

Links

239000002502 liposome Substances 0.000 title abstract 4
230000018044 dehydration Effects 0.000 title 1
238000006297 dehydration reaction Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
239000004480 active ingredient Substances 0.000 abstract 2
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
229940079593 drug Drugs 0.000 abstract 2
239000003814 drug Substances 0.000 abstract 2
150000002632 lipids Chemical class 0.000 abstract 2
229930012538 Paclitaxel Natural products 0.000 abstract 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
-1 anionic lipid Chemical class 0.000 abstract 1
235000012000 cholesterol Nutrition 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229960001592 paclitaxel Drugs 0.000 abstract 1
WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1
RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Oncology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Manufacturing Of Micro-Capsules (AREA)

AT01948934T 2000-02-04 2001-01-31 Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome ATE341310T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP00300904		2000-02-04

Publications (1)

Publication Number	Publication Date
ATE341310T1 true ATE341310T1 (de)	2006-10-15

Family

ID=8172682

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01948934T ATE341310T1 (de)	2000-02-04	2001-01-31	Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome

Country Status (8)

Country	Link
US (1)	US7025988B2 (de)
EP (1)	EP1259225B1 (de)
JP (1)	JP4786105B2 (de)
AT (1)	ATE341310T1 (de)
AU (1)	AU2869901A (de)
DE (1)	DE60123583T2 (de)
ES (1)	ES2272496T3 (de)
WO (1)	WO2001056548A2 (de)

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US9114081B2 (en)	2007-05-07	2015-08-25	Insmed Incorporated	Methods of treating pulmonary disorders with liposomal amikacin formulations
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2001
- 2001-01-31 AT AT01948934T patent/ATE341310T1/de not_active IP Right Cessation
- 2001-01-31 WO PCT/GB2001/000391 patent/WO2001056548A2/en not_active Ceased
- 2001-01-31 JP JP2001556240A patent/JP4786105B2/ja not_active Expired - Fee Related
- 2001-01-31 EP EP01948934A patent/EP1259225B1/de not_active Expired - Lifetime
- 2001-01-31 DE DE60123583T patent/DE60123583T2/de not_active Expired - Lifetime
- 2001-01-31 ES ES01948934T patent/ES2272496T3/es not_active Expired - Lifetime
- 2001-01-31 AU AU28699/01A patent/AU2869901A/en not_active Abandoned
- 2001-01-31 US US10/182,921 patent/US7025988B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO2001056548A3 (en)	2002-03-21
AU2869901A (en)	2001-08-14
ES2272496T3 (es)	2007-05-01
JP4786105B2 (ja)	2011-10-05
EP1259225B1 (de)	2006-10-04
DE60123583D1 (de)	2006-11-16
US20030138481A1 (en)	2003-07-24
DE60123583T2 (de)	2007-08-09
EP1259225A2 (de)	2002-11-27
JP2003521508A (ja)	2003-07-15
US7025988B2 (en)	2006-04-11
WO2001056548A2 (en)	2001-08-09

Legal Events

Date	Code	Title	Description
2007-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE60123583D1 (de)	2006-11-16	Dehydratisierungs-/rehydratisierungsverfahren zur herstellung von liposome
EP0277776A3 (de)	1989-09-27	Liposome mit harten Kernen
US5262168A (en)	1993-11-16	Prostaglandin-lipid formulations
US5082664A (en)	1992-01-21	Prostaglandin-lipid formulations
TW359616B (en)	1999-06-01	A parenterally administered pharmaceutical composition for lipophilic, poorly soluble active compounds, in the form of liposomes with phospholipid membranes
NZ334561A (en)	2000-01-28	Preparation of multivesicular liposomes for controPreparation of multivesicular liposomes for controlled release of active agents lled release of active agents
DE69614385D1 (de)	2001-09-13	Verfahren zur herstellung einer liposomen-zubereitung
AU8141891A (en)	1991-10-10	Unilamellar vesicles
CA2138925A1 (en)	1995-07-01	Method of producing reconstituted lipoproteins
WO1999016426A3 (en)	1999-06-17	Multilamellar coalescence vesicles (mlcv) containing biologically active compounds
NZ538179A (en)	2008-09-26	Liposome or lipid complex with active platinum compound and process for producing the same
HK1007496B (en)	1999-04-16	Prostaglandin-lipid formulations
NZ508960A (en)	2002-11-26	Method of forming liposomes
CA2227761A1 (en)	1997-02-13	Methods of making liposomes containing hydro-monobenzoporphyrin photosensitizers
KR880001284A (ko)	1988-04-22	단일 이중층 리포좀의 제조방법
FR2634375B3 (fr)	1991-07-05	Procede de preparation de systemes colloidaux dispersibles de lipide amphiphiles sous forme de liposomes submicroniques
HUT62457A (en)	1993-05-28	Process for producing aqueous liposomal suspensions comprising an active ingredient
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DE59914774D1 (de)	2008-07-10	Verfahren zur herstellung von liposomalen wirkstoffformulierungen
KR19990021864A (ko)	1999-03-25	탈모증 치료 및 예방을 위한 국소 외용제
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ATE308975T1 (de)	2005-11-15	Dinitroanilin enthaltende liposomen und verfahren zur herstellung derselben