ATE341562T1 - Verfahren zur darstellung von lh-rh-derivaten - Google Patents
Verfahren zur darstellung von lh-rh-derivatenInfo
- Publication number
- ATE341562T1 ATE341562T1 AT00942386T AT00942386T ATE341562T1 AT E341562 T1 ATE341562 T1 AT E341562T1 AT 00942386 T AT00942386 T AT 00942386T AT 00942386 T AT00942386 T AT 00942386T AT E341562 T1 ATE341562 T1 AT E341562T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- resin adsorbent
- synthetic
- treatment
- impurities
- Prior art date
Links
- XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical class C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 239000003463 adsorbent Substances 0.000 abstract 2
- 239000012535 impurity Substances 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000113 methacrylic resin Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18630799 | 1999-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE341562T1 true ATE341562T1 (de) | 2006-10-15 |
Family
ID=16186046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00942386T ATE341562T1 (de) | 1999-06-30 | 2000-06-29 | Verfahren zur darstellung von lh-rh-derivaten |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050261195A1 (de) |
| EP (2) | EP1207167B1 (de) |
| AT (1) | ATE341562T1 (de) |
| AU (1) | AU5705500A (de) |
| CA (1) | CA2376763C (de) |
| DE (1) | DE60031133T2 (de) |
| WO (1) | WO2001002428A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2119724A1 (de) * | 2005-05-03 | 2009-11-18 | Novetide Ltd. | Festphaseverfahren zur Herstellung von Goserelin |
| KR100722607B1 (ko) | 2006-05-11 | 2007-05-28 | 주식회사 펩트론 | 분산성 및 주사 투여능이 향상된 서방성 미립구의 제조방법 |
| CN101195653B (zh) * | 2006-12-08 | 2010-05-12 | 吉尔生化（上海）有限公司 | 亮丙瑞林的固液合成法 |
| AU2008306190A1 (en) * | 2007-09-11 | 2009-04-09 | Mondobiotech Laboratories Ag | Use of bubuc and optionally EAA-MART1 (26-35) as a therapeutic agent for the treatment of HCMV infections |
| CN118047836A (zh) * | 2024-01-19 | 2024-05-17 | 中肽生化有限公司 | 一种戈舍瑞林杂质e的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3816386A (en) * | 1972-06-20 | 1974-06-11 | Abbott Lab | Purification process for gn-rh |
| CS180644B2 (en) * | 1973-09-29 | 1978-01-31 | Takeda Chemical Industries Ltd | Process for preparing nonapeptides |
| US3997516A (en) * | 1974-07-04 | 1976-12-14 | Takeda Chemical Industries, Ltd. | Method for protecting guanidino group and restoring the same |
| CA1283072C (en) * | 1986-12-01 | 1991-04-16 | Timothy Durance | Process for the isolation and separation of lysozyme and avidin from eggwhite |
| US6211333B1 (en) * | 1996-06-21 | 2001-04-03 | Takeda Chemical Industries, Ltd. | Method for producing peptides and their salts which have an agonist activity of luteinizing hormone releasing hormones secreted from the hypothalamus |
| JP3020141B2 (ja) * | 1996-10-07 | 2000-03-15 | 株式会社富士薬品 | 経鼻投与用製剤 |
-
2000
- 2000-06-29 CA CA002376763A patent/CA2376763C/en not_active Expired - Fee Related
- 2000-06-29 DE DE60031133T patent/DE60031133T2/de not_active Expired - Lifetime
- 2000-06-29 AU AU57055/00A patent/AU5705500A/en not_active Abandoned
- 2000-06-29 EP EP00942386A patent/EP1207167B1/de not_active Expired - Lifetime
- 2000-06-29 WO PCT/JP2000/004277 patent/WO2001002428A1/ja not_active Ceased
- 2000-06-29 AT AT00942386T patent/ATE341562T1/de not_active IP Right Cessation
- 2000-06-29 EP EP06002729A patent/EP1777232A1/de not_active Withdrawn
-
2005
- 2005-04-07 US US11/101,895 patent/US20050261195A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60031133T2 (de) | 2007-04-12 |
| CA2376763A1 (en) | 2001-01-11 |
| AU5705500A (en) | 2001-01-22 |
| EP1777232A1 (de) | 2007-04-25 |
| EP1207167B1 (de) | 2006-10-04 |
| US20050261195A1 (en) | 2005-11-24 |
| CA2376763C (en) | 2009-12-22 |
| EP1207167A1 (de) | 2002-05-22 |
| WO2001002428A1 (en) | 2001-01-11 |
| DE60031133D1 (de) | 2006-11-16 |
| EP1207167A4 (de) | 2003-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |