ATE342065T1 - Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvant - Google Patents

Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvant

Info

Publication number: ATE342065T1
Authority: AT; Austria
Prior art keywords: sub; adjuvant; fatty acids; monoglycerides; vaccine formulation
Prior art date: 1999-02-12

Application number

AT00906305T

Other languages

English (en)

Inventor

Ulf Schroeder

Stefan Svenson

Original Assignee

Eurocine Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-12

Filing date

2000-02-09

Publication date

2006-11-15

2000-02-09 Application filed by Eurocine Ab filed Critical Eurocine Ab

2006-11-15 Application granted granted Critical

2006-11-15 Publication of ATE342065T1 publication Critical patent/ATE342065T1/de

Links

239000000203 mixture Substances 0.000 title abstract 3
201000008827 tuberculosis Diseases 0.000 title abstract 3
239000002671 adjuvant Substances 0.000 title abstract 2
235000014113 dietary fatty acids Nutrition 0.000 title abstract 2
229930195729 fatty acid Natural products 0.000 title abstract 2
239000000194 fatty acid Substances 0.000 title abstract 2
150000004665 fatty acids Chemical class 0.000 title abstract 2
229960005486 vaccine Drugs 0.000 title abstract 2
OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical compound CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 title 1
238000009472 formulation Methods 0.000 title 1
LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 2
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 2
241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
230000003053 immunization Effects 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Mycology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT00906305T 1999-02-12 2000-02-09 Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvant ATE342065T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9900495A SE9900495D0 (sv)	1999-02-12	1999-02-12	Vaccine composition

Publications (1)

Publication Number	Publication Date
ATE342065T1 true ATE342065T1 (de)	2006-11-15

Family

ID=20414469

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00906305T ATE342065T1 (de)	1999-02-12	2000-02-09	Impfstofformulierung gegen tuberkulose mit monoglyceriden oder fettsäuren als adjuvant

Country Status (10)

Country	Link
US (1)	US6936260B1 (de)
EP (1)	EP1154792B1 (de)
AT (1)	ATE342065T1 (de)
AU (1)	AU769390B2 (de)
DE (1)	DE60031243T2 (de)
DK (1)	DK1154792T3 (de)
ES (1)	ES2275495T3 (de)
NZ (1)	NZ513130A (de)
SE (1)	SE9900495D0 (de)
WO (1)	WO2000047225A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AUPR030800A0 (en) *	2000-09-22	2000-10-12	Pharmalink International Limited	Immunomodulatory preparation
AU2002364952B2 (en) *	2001-11-14	2008-04-10	Novavax, Inc.	Mycobacterial vaccine
ATE466585T1 (de) *	2001-12-11	2010-05-15	Pasteur Institut	Präparationen grampositiver bakterien zur behandlung von krankheiten mit immunfehlregulation
CU23476A1 (es) *	2004-01-29	2009-12-17	Ct Ingenieria Genetica Biotech	Formulación adyuvante conteniendo una emulsión oleosa con aceite de jojoba
WO2006079989A2 (en) *	2005-01-28	2006-08-03	North-West University	Lipid and nitrous oxide combination as adjuvant for the enhancement of the efficacy of vaccines
JP5713672B2 (ja) *	2007-04-12	2015-05-07	ジェニファーライター，	結核のワクチンおよびその使用方法
CN102441162B (zh) *	2010-10-04	2018-07-24	免疫产品美国股份有限公司	结核病的治疗和预防
CA2833633A1 (en) *	2011-04-20	2012-10-26	Jason Fisher	Composition and method for enhancing an immune response
EP2620159A1 (de) *	2012-01-24	2013-07-31	Institut Pasteur	Verbesserte Krebsbehandlung durch Immuntherapie mit BCG- oder antigenetisch ähnlichen nicht-pathogenen Mykobakterien
WO2018006939A1 (en)	2016-07-05	2018-01-11	Universidad De Zaragoza	Inactivated tuberculosis vaccine
WO2020115161A1 (en)	2018-12-04	2020-06-11	Sabiotec Spin-Off Sl	Immunostimulant for use against pathogens

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990014837A1 (en) *	1989-05-25	1990-12-13	Chiron Corporation	Adjuvant formulation comprising a submicron oil droplet emulsion
WO1993006921A1 (en)	1991-10-04	1993-04-15	Gs Biochem Ab	Particles, method of preparing said particles and uses thereof
DK17093D0 (da) *	1993-02-15	1993-02-15	Lyfjathroun H F	Farmaceutisk praeparat til topisk administrering af antigener og/eller vacciner til pattedyr via slimhinder
DE69735294T2 (de) *	1996-03-25	2006-09-21	Medarex Inc.	Spezifische monoklonale antikörper für die extrazelluläre domäne von protasta-spezifischem membranantigen
SE9602280D0 (sv) *	1996-06-10	1996-06-10	Pharmatrix Ab	Immunstimulerande lipidformulering

1999
- 1999-02-12 SE SE9900495A patent/SE9900495D0/xx unknown
2000
- 2000-02-09 WO PCT/EP2000/001046 patent/WO2000047225A2/en not_active Ceased
- 2000-02-09 DK DK00906305T patent/DK1154792T3/da active
- 2000-02-09 EP EP00906305A patent/EP1154792B1/de not_active Expired - Lifetime
- 2000-02-09 DE DE60031243T patent/DE60031243T2/de not_active Expired - Lifetime
- 2000-02-09 AT AT00906305T patent/ATE342065T1/de not_active IP Right Cessation
- 2000-02-09 US US09/926,001 patent/US6936260B1/en not_active Expired - Fee Related
- 2000-02-09 NZ NZ513130A patent/NZ513130A/xx not_active IP Right Cessation
- 2000-02-09 AU AU28035/00A patent/AU769390B2/en not_active Ceased
- 2000-02-09 ES ES00906305T patent/ES2275495T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK1154792T3 (da)	2007-02-12
WO2000047225A3 (en)	2000-12-14
DE60031243T2 (de)	2007-05-24
US6936260B1 (en)	2005-08-30
SE9900495D0 (sv)	1999-02-12
WO2000047225A2 (en)	2000-08-17
ES2275495T3 (es)	2007-06-16
AU769390B2 (en)	2004-01-22
EP1154792A2 (de)	2001-11-21
EP1154792B1 (de)	2006-10-11
DE60031243D1 (de)	2006-11-23
AU2803500A (en)	2000-08-29
NZ513130A (en)	2003-01-31

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Legal Events

Date	Code	Title	Description
2007-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties