ATE342723T1 - Behandlung von neurodegenerativen gastrointestinalen krankheiten durch implantation von neuralen stammzellen und/oder deren nachkommen in gastrointestinalorgane - Google Patents

Behandlung von neurodegenerativen gastrointestinalen krankheiten durch implantation von neuralen stammzellen und/oder deren nachkommen in gastrointestinalorgane

Info

Publication number: ATE342723T1
Authority: AT; Austria
Prior art keywords: gastrointestinal; stem cells; progents; neurodegenerative; implantation
Prior art date: 2000-04-13

Application number

AT01926922T

Other languages

English (en)

Inventor

Pankaj Jay Pasricha

Maria A Micci

Original Assignee

Univ Texas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-04-13

Filing date

2001-04-12

Publication date

2006-11-15

2001-04-12 Application filed by Univ Texas filed Critical Univ Texas

2006-11-15 Application granted granted Critical

2006-11-15 Publication of ATE342723T1 publication Critical patent/ATE342723T1/de

Links

208000018522 Gastrointestinal disease Diseases 0.000 title abstract 2
230000002496 gastric effect Effects 0.000 title abstract 2
210000000056 organ Anatomy 0.000 title abstract 2
238000002513 implantation Methods 0.000 title 1
210000001178 neural stem cell Anatomy 0.000 title 1
230000000626 neurodegenerative effect Effects 0.000 title 1
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
210000000130 stem cell Anatomy 0.000 abstract 2
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
208000010643 digestive system disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000018685 gastrointestinal system disease Diseases 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
210000000496 pancreas Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Cell Biology (AREA)
Microbiology (AREA)
Neurosurgery (AREA)
Developmental Biology & Embryology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

AT01926922T 2000-04-13 2001-04-12 Behandlung von neurodegenerativen gastrointestinalen krankheiten durch implantation von neuralen stammzellen und/oder deren nachkommen in gastrointestinalorgane ATE342723T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19680600P	2000-04-13	2000-04-13
US23230100P	2000-09-12	2000-09-12

Publications (1)

Publication Number	Publication Date
ATE342723T1 true ATE342723T1 (de)	2006-11-15

Family

ID=26892243

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01926922T ATE342723T1 (de)	2000-04-13	2001-04-12	Behandlung von neurodegenerativen gastrointestinalen krankheiten durch implantation von neuralen stammzellen und/oder deren nachkommen in gastrointestinalorgane

Country Status (7)

Country	Link
US (1)	US6808702B2 (de)
EP (1)	EP1272203B1 (de)
JP (1)	JP2003531124A (de)
AT (1)	ATE342723T1 (de)
AU (1)	AU2001253425A1 (de)
DE (1)	DE60123937T2 (de)
WO (1)	WO2001078752A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0102717D0 (en) *	2001-02-02	2001-03-21	Medical Res Council	Cells and uses therefor
AU2003202988A1 (en) *	2002-01-14	2003-07-30	The Board Of Trustees Of The University Of Illinois	Use of modified pyrimidine compounds to promote stem cell migration and proliferation
US20040071674A1 (en) *	2002-03-19	2004-04-15	Hiroshi Mashimo	Therapeutic treatment of digestive organs with engineered stem cells
KR100558811B1 (ko) *	2003-12-16	2006-03-10	엘지전자 주식회사	스크롤 압축기의 밀봉력 조절장치
WO2007016099A2 (en) *	2005-07-29	2007-02-08	Musc Foundation For Research Development	Protection of transplanted stem cells with hmg-coa reductase inhibitors
US8021355B2 (en)	2005-08-12	2011-09-20	Board Of Regents The University Of Texas System	System, kit, and method of transgastric removal of visceral fat and other related methods
WO2009018626A1 (en) *	2007-08-09	2009-02-12	Murdoch Childrens Research Institute	A therapeutic protocol using stem cells in tissue and neuronal repair, maintenance, regeneration and augmentation
JP5294041B2 (ja) *	2008-06-27	2013-09-18	独立行政法人産業技術総合研究所	膵臓疾患又は糖尿病のための膵臓細胞再生移植用キット
US9101570B1 (en) *	2009-02-13	2015-08-11	Endocellutions, Inc.	Adult and neonatal stem cell therapy to treat diabetes through the repair of the gastrointestinal tract
US9352000B2 (en)	2010-05-05	2016-05-31	Rappaport Family Institute For Research In The Medical Sciences	Use of CCL1 in therapy
US20170077320A1 (en) *	2015-09-11	2017-03-16	Solarcity Corporation	Anti-corrosion protection of photovoltaic structures

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5851832A (en)	1991-07-08	1998-12-22	Neurospheres, Ltd.	In vitro growth and proliferation of multipotent neural stem cells and their progeny
US6497872B1 (en) *	1991-07-08	2002-12-24	Neurospheres Holdings Ltd.	Neural transplantation using proliferated multipotent neural stem cells and their progeny
US5981165A (en)	1991-07-08	1999-11-09	Neurospheres Holdings Ltd.	In vitro induction of dopaminergic cells
US5980885A (en)	1991-07-08	1999-11-09	Neurospheres Holdings Ltd.	Growth factor-induced proliferation of neural precursor cells in vivo
US5175103A (en)	1991-10-21	1992-12-29	Trustees Of University Of Pennsylvania	Preparation of pure cultures of post-mitotic human neurons
US5753491A (en)	1993-04-13	1998-05-19	Us Health	Use of neuro-derived fetal cell lines for transplantation therapy
PT696205E (pt)	1993-04-13	2002-07-31	Us Gov Health & Human Serv	Utilizacao de linhas celulares fetais nauro-derivadas para terapia de transplantacao
US5753505A (en)	1995-07-06	1998-05-19	Emory University	Neuronal progenitor cells and uses thereof
CA2262817A1 (en)	1996-08-19	1998-02-26	James Robl	Embryonic or stem-like cell lines produced by cross species nuclear transplantation
US6025157A (en)	1997-02-18	2000-02-15	Genentech, Inc.	Neurturin receptor
US5968829A (en)	1997-09-05	1999-10-19	Cytotherapeutics, Inc.	Human CNS neural stem cells
SE9802264D0 (sv) *	1998-06-25	1998-06-25	Neuronova Ab	A method of isolating cells
US6129911A (en)	1998-07-10	2000-10-10	Rhode Island Hospital, A Lifespan Partner	Liver stem cell

2001
- 2001-04-12 AT AT01926922T patent/ATE342723T1/de not_active IP Right Cessation
- 2001-04-12 AU AU2001253425A patent/AU2001253425A1/en not_active Abandoned
- 2001-04-12 US US09/834,110 patent/US6808702B2/en not_active Expired - Fee Related
- 2001-04-12 EP EP01926922A patent/EP1272203B1/de not_active Expired - Lifetime
- 2001-04-12 WO PCT/US2001/011999 patent/WO2001078752A2/en not_active Ceased
- 2001-04-12 JP JP2001576052A patent/JP2003531124A/ja active Pending
- 2001-04-12 DE DE60123937T patent/DE60123937T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US6808702B2 (en)	2004-10-26
EP1272203B1 (de)	2006-10-18
EP1272203A2 (de)	2003-01-08
DE60123937T2 (de)	2007-06-14
US20020001578A1 (en)	2002-01-03
WO2001078752A2 (en)	2001-10-25
JP2003531124A (ja)	2003-10-21
DE60123937D1 (de)	2006-11-30
AU2001253425A1 (en)	2001-10-30
WO2001078752A3 (en)	2002-05-23

Legal Events

Date	Code	Title	Description
2007-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE342723T1 (de)	2006-11-15	Behandlung von neurodegenerativen gastrointestinalen krankheiten durch implantation von neuralen stammzellen und/oder deren nachkommen in gastrointestinalorgane
Lohfink	2014	Does God Need the Church?: Toward a Theology of the People of God
Middleton	1982	Lugbara death
Jenner	1995	The politics of London air John Evelyn's Fumifugium and the Restoration
TW200603838A (en)	2006-02-01	Extended release biodegradable ocular implants
DK1005358T3 (da)	2003-02-24	Anvendelse af et neurturinprotein-produkt til forebyggelse og behandling af hørenedsættelse
ATE266417T1 (de)	2004-05-15	Medikamente zur vorbeugung oder behandlung von vaskulären hämorrhagien
BR0112361A (pt)	2003-05-20	Métodos para tratamento de condições oculares mediadas por inflamação
DE69626205D1 (de)	2003-03-20	Terminal-sterilisierte osteogene vorrichtungen und ihre herstellung
WO2008013737A3 (en)	2008-11-06	Compositions for reprogramming a cell and uses therefor
DK0756498T3 (da)	2002-11-11	Behandling af biologisk materiale før fiksering
May	1985	The virtues and vices of the elderly
DE69525151D1 (de)	2002-03-14	Methoden zur krankheitsbehandlung unter verwendung von sertoli-zellen und allotransplantat oder xenotransplantat
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DE69429299D1 (de)	2002-01-17	Verwendung von Tachykinin-Antagonisten zur Behandlung von Erbrechen
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DK1274464T3 (da)	2012-01-23	Sammensætninger og fremgangsmåder til regulering af proteinekspression i tarm
DE602004024221D1 (de)	2009-12-31	Behandlung von entzündlichen darmerkrankungen mit 2-methylen-19-nor-vitamin d verbindungen
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DE50100833D1 (de)	2003-11-27	Verwendung von 2-methyl-thiazolidin-2,4-dicarbonsäure und / oder ihrer physiologisch verträglichen salze zur herstellung eines medikaments zur behandlung von krebserkrankungen
Betz	1992	An introduction to the thought of Hannah Arendt
ATE268170T1 (de)	2004-06-15	Verwendung von bernsteisäure oder deren salze zur behandlung von insulinresistenz
Rasolondraibe	1989	Healing ministry in Madagascar